• Title/Summary/Keyword: Performance testing

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Preoperative Prediction for Early Recurrence Can Be as Accurate as Postoperative Assessment in Single Hepatocellular Carcinoma Patients

  • Dong Ik Cha;Kyung Mi Jang;Seong Hyun Kim;Young Kon Kim;Honsoul Kim;Soo Hyun Ahn
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.402-412
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    • 2020
  • Objective: To evaluate the performance of predicting early recurrence using preoperative factors only in comparison with using both pre-/postoperative factors. Materials and Methods: We retrospectively reviewed 549 patients who had undergone curative resection for single hepatcellular carcinoma (HCC) within Milan criteria. Multivariable analysis was performed to identify pre-/postoperative high-risk factors of early recurrence after hepatic resection for HCC. Two prediction models for early HCC recurrence determined by stepwise variable selection methods based on Akaike information criterion were built, either based on preoperative factors alone or both pre-/postoperative factors. Area under the curve (AUC) for each receiver operating characteristic curve of the two models was calculated, and the two curves were compared for non-inferiority testing. The predictive models of early HCC recurrence were internally validated by bootstrap resampling method. Results: Multivariable analysis on preoperative factors alone identified aspartate aminotransferase/platelet ratio index (OR, 1.632; 95% CI, 1.056-2.522; p = 0.027), tumor size (OR, 1.025; 95% CI, 0.002-1.049; p = 0.031), arterial rim enhancement of the tumor (OR, 2.350; 95% CI, 1.297-4.260; p = 0.005), and presence of nonhypervascular hepatobiliary hypointense nodules (OR, 1.983; 95% CI, 1.049-3.750; p = 0.035) on gadoxetic acid-enhanced magnetic resonance imaging as significant factors. After adding postoperative histopathologic factors, presence of microvascular invasion (OR, 1.868; 95% CI, 1.155-3.022; p = 0.011) became an additional significant factor, while tumor size became insignificant (p = 0.119). Comparison of the AUCs of the two models showed that the prediction model built on preoperative factors alone was not inferior to that including both pre-/postoperative factors {AUC for preoperative factors only, 0.673 (95% confidence interval [CI], 0.623-0.723) vs. AUC after adding postoperative factors, 0.691 (95% CI, 0.639-0.744); p = 0.0013}. Bootstrap resampling method showed that both the models were valid. Conclusion: Risk stratification solely based on preoperative imaging and laboratory factors was not inferior to that based on postoperative histopathologic risk factors in predicting early recurrence after curative resection in within Milan criteria single HCC patients.

Diagnostic value of serum procalcitonin and C-reactive protein in discriminating between bacterial and nonbacterial colitis: a retrospective study

  • Jae Yong Lee;So Yeon Lee;Yoo Jin Lee;Jin Wook Lee;Jeong Seok Kim;Ju Yup Lee;Byoung Kuk Jang;Woo Jin Chung;Kwang Bum Cho;Jae Seok Hwang
    • Journal of Yeungnam Medical Science
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    • v.40 no.4
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    • pp.388-393
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    • 2023
  • Background: Differentiating between bacterial and nonbacterial colitis remains a challenge. We aimed to evaluate the value of serum procalcitonin (PCT) and C-reactive protein (CRP) in differentiating between bacterial and nonbacterial colitis. Methods: Adult patients with three or more episodes of watery diarrhea and colitis symptoms within 14 days of a hospital visit were eligible for this study. The patients' stool pathogen polymerase chain reaction (PCR) testing results, serum PCT levels, and serum CRP levels were analyzed retrospectively. Patients were divided into bacterial and nonbacterial colitis groups according to their PCR. The laboratory data were compared between the two groups. The area under the receiver operating characteristic curve (AUC) was used to evaluate diagnostic accuracy. Results: In total, 636 patients were included; 186 in the bacterial colitis group and 450 in the nonbacterial colitis group. In the bacterial colitis group, Clostridium perfringens was the commonest pathogen (n=70), followed by Clostridium difficile toxin B (n=60). The AUC for PCT and CRP was 0.557 and 0.567, respectively, indicating poor discrimination. The sensitivity and specificity for diagnosing bacterial colitis were 54.8% and 52.6% for PCT, and 52.2% and 54.2% for CRP, respectively. Combining PCT and CRP measurements did not increase the discrimination performance (AUC, 0.522; 95% confidence interval, 0.474-0.571). Conclusion: Neither PCT nor CRP helped discriminate bacterial colitis from nonbacterial colitis.

Experimental study on ultra-high strength concrete(130 MPa) (초고강도 콘크리트(130MPa)에 대한 실험적 연구)

  • Cho Choonhwan;Yang Dong-il
    • Journal of the Korea Institute of Construction Safety
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    • v.6 no.1
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    • pp.12-18
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    • 2024
  • High-rise, large-scale, and diversification of buildings are possible, and the reduction of concrete cross-sections reduces the weight of the structure, thereby increasing or decreasing the height of the floor, securing a large number of floors at the same height, securing a large effective space, and reducing the amount of materials, rebar, and concrete used for designating the foundation floor. In terms of site construction and quality, a low water binder ratio can reduce the occurrence of dry shrinkage and minimize bleeding on the concrete surface. It has the advantage of securing self-fulfilling properties by improving fluidity by using high-performance sensitizers, making it easier to construct the site, and shortening the mold removal period by expressing early strength of concrete. In particular, with the rapid development of concrete-related construction technology in recent years, the application of ultra-high-strength concrete with a design standard strength of 100 MPa or higher is expanding in high-rise buildings. However, although high-rise buildings with more than 120 stories have recently been ordered or scheduled in Korea, the research results of developing ultra-high-strength concrete with more than 130 MPa class considering field applicability and testing and evaluating the actual applicability in the field are insufficient. In this study, in order to confirm the applicability of ultra-high-strength concrete in the field, a preliminary experiment for the member of a reduced simulation was conducted to find the optimal mixing ratio studied through various indoor basic experiments. After that, 130 MPa-class ultra-high-strength concrete was produced in a ready-mixed concrete factory in a mock member similar to the life size, and the flow characteristics, strength characteristics, and hydration heat of concrete were experimentally studied through on-site pump pressing.

Evaluation of Hydrogeological Characteristics of Deep-Depth Rock Aquifer in Volcanic Rock Area (화산암 지역 고심도 암반대수층 수리지질특성 평가)

  • Hangbok Lee;Chan Park;Junhyung Choi;Dae-Sung Cheon;Eui-Seob Park
    • Tunnel and Underground Space
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    • v.34 no.3
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    • pp.231-247
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    • 2024
  • In the field of high-level radioactive waste disposal targeting deep rock environments, hydraulic characteristic information serves as the most important key factor in selecting relevant disposal sites, detailed design of disposal facilities, derivation of optimal construction plans, and safety evaluation during operation. Since various rock types are mixed and distributed in a small area in Korea, it is important to conduct preliminary work to analyze the hydrogeological characteristics of rock aquifers for various rock types and compile the resulting data into a database. In this paper, we obtained hydraulic conductivity data, which is the most representative field hydraulic characteristic of a high-depth volcanic bedrock aquifer, and also analyzed and evaluated the field data. To acquire field data, we used a high-performance hydraulic testing system developed in-house and applied standardized test methods and investigation procedures. In the process of hydraulic characteristic data analysis, hydraulic conductivity values were obtained for each depth, and the pattern of groundwater flow through permeable rock joints located in the test section was also evaluated. It is expected that the series of data acquisition methods, procedures, and analysis results proposed in this report can be used to build a database of hydraulic characteristics data for high-depth rock aquifers in Korea. In addition, it is expected that it will play a role in improving technical know-how to be applied to research on hydraulic characteristic according to various bedrock types in the future.

The Application of Entomopathogenic Fungi Metarhizium anisopliae, Beauveria bassiana, and Trichoderma harzianum for Coptotermes curvignathus and Cryptotermes cynocephalus Termite Control in Indonesia

  • Niken SUBEKTI;Ari SUSILOWATI;Elizabeth Novi KUSUMANINGRUM;Anita FADHILA;Sania SALSABILA;Citra Anisah ZAHRA;Nasiha Al SABRINA;Ikhsan GUSWENRIVO;Yayan SANJAYA;Cepi KURNIAWAN;Apri Heri ISWANTO;Mia MIRANTI
    • Journal of the Korean Wood Science and Technology
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    • v.52 no.3
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    • pp.262-275
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    • 2024
  • In Indonesia, Coptotermes curvignathus Holmgren and Cryptotermes cyanocephalus Light termite attacks can damage wood and causing losses of 8.7 trillion rupiah per year. Wood treatment and soil barrier are very important to protect structures and their components from termite infestation. The application of synthetic chemicals that pose risks to the environment and human health. The growing movement to replace these chemicals with new termiticides that are safe for the environment in place of persistent organic pollutants. Efficacy performance in entomopathogenic fungi spores such as that produce decanoic acid, hexadecanoic acid, palmitic acid, and octadecadienoic acid are potential compounds that provide for ecofriendly termite control. Entomopathogenic fungal spores from Metarhizium anisopliae, Trichoderma harzianum, and Beauveria bassiana, as the active ingredient were formulated with nanocellulose was added as an inert ingredient to which helped to deliver the active ingredients on controlling the target pest, and enhance the utility ability of the product fungi to control termites. The mortality of these termites successively entomopathogenic fungi was the main cause of death. The higher concentrations being associated with of nanocellulose used affect increased the number of termites mortality. M. anisopliae paired with 60% nanocellulose concentrate was the best percentage for yielded the greatest C. curvignathus and C. cynocephalus termite control. In the field testing, M. anisopliae provided better, it showed the finest result of termite control rather than B. bassiana and T. harzianum. The results of the research indicate that entomopathogenic fungi can be used for Pest Control Management as the subterranean termite and drywood termite control.

Investigation of Tensile Properties in Edge Modified Graphene Oxide(E-GO)/Epoxy Nano Composites (측면 치환 그래핀/에폭시 나노복합재료의 인장 특성 평가)

  • Donghyeon Lee;Ga In Cho;Hyung Mi Lim;Mantae Kim;Dong-Jun Kwon
    • Composites Research
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    • v.37 no.3
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    • pp.209-214
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    • 2024
  • Graphene oxide (GO), known for its high stiffness, thermal conductivity, and electrical conductivity, is being utilized as a reinforcement in nanocomposite materials. This study evaluates the mechanical properties of epoxy nanocomposites incorporating GO and edge modified GO (E-GO), which has hydroxyl groups substituted only on its edges. GO/E-GO was uniformly dispersed in epoxy resin using ultrasonic dispersion, and mechanical properties were assessed through tensile testing. The results showed that the addition of nanoparticles increased both tensile strength and toughness. The tensile strength of the epoxy without nanoparticles was 74.4 MPa, while the highest tensile strength of 90.7 MPa was observed with 0.3 wt% E-GO. Additionally, the modulus increased from 2.55 GPa to 3.53 GPa with the addition of nanoparticles. Field emission scanning electron microscopy of the fracture surface revealed that the growth of cracks was impeded by the nanoparticles, preventing complete fracture and causing the cracks to split in multiple directions. E-GO, with surface treatment only on the edges, exhibited higher mechanical properties than GO due to its superior dispersion and surface treatment effects. These results highlight the importance of nanoparticle surface treatment in developing high-performance nanocomposite materials.

Empirical Study on Survival Factors of Youth Start-Ups (청년창업기업의 생존요인에 관한 실증연구)

  • Choon Ju Park;Jae Bum Hong
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.18 no.6
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    • pp.27-40
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    • 2023
  • This study analyzes the factors affecting the survival of young start-up companies. A youth start-up company was defined as a company with a founder's age under 39. The study was based on evaluation data from 3,540 companies evaluated by the Technology Guarantee Fund to support youth start-up guarantees during the period from 2012 to 2015. In this study, independent variables were defined as founder characteristics, start-up environment, and start-up strategy, and entrepreneurship, knowledge level, and development capabilities were set as variables for start-up characteristics, competition conditions and comparative advantage with alternatives in the start-up environment, and item novelty, commercialization plan and financing plan were set as variables. For variable measurement, the evaluation index of the youth start-up evaluation model of the Technology Guarantee Fund was used. Management performance was defined as the survival of a company, and the survival of 12, 36, 60, and 84 months was measured based on the occurrence of insolvency registered by the Korea Technology Guarantee Fund. The Cox proportional risk model was used for hypothesis testing. As a result of the analysis, knowledge level and development capability were statistically significant in the characteristics of the founder, and the financing plan in the start-up strategy was statistically significant regardless of the survival period. Among the start-up strategies, the novelty of the item had a positive effect on survival after 36 months. Entrepreneurship was significant only in 12-month survival. The most important order for survival was identified in the order of financing plan, knowledge level, item novelty and development capability, of which the founder's knowledge level in the beginning and the funding plan in the second half had the greatest impact.

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Proposal for Research Model of High-Function Patrol Robot using Integrated Sensor System (통합 센서 시스템을 이용한 고기능 순찰 로봇의 연구모델 제안)

  • Byeong-Cheon Yoo;Seung-Jung Shin
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.24 no.3
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    • pp.77-85
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    • 2024
  • In this dissertation, a we designed and implemented a patrol robot that integrates a thermal imaging camera, speed dome camera, PTZ camera, radar, lidar sensor, and smartphone. This robot has the ability to monitor and respond efficiently even in complex environments, and is especially designed to demonstrate high performance even at night or in low visibility conditions. An orbital movement system was selected for the robot's mobility, and a smartphone-based control system was developed for real-time data processing and decision-making. The combination of various sensors allows the robot to comprehensively perceive the environment and quickly detect hazards. Thermal imaging cameras are used for night surveillance, speed domes and PTZ cameras are used for wide-area monitoring, and radar and LIDAR are used for obstacle detection and avoidance. The smartphone-based control system provides a user-friendly interface. The proposed robot system can be used in various fields such as security, surveillance, and disaster response. Future research should include improving the robot's autonomous patrol algorithm, developing a multi-robot collaboration system, and long-term testing in a real environment. This study is expected to contribute to the development of the field of intelligent surveillance robots.

Correlation Analysis of Rail Surface Defects and Rail Internal Cracks (레일표면결함과 레일내부균열의 상관관계 분석)

  • Jung-Youl Choi;Jae-Min Han;Young-Ki Kim
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.1
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    • pp.585-590
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    • 2024
  • In this study, rail surface defects are increasing due to the aging of urban railway rails, but in the detailed guidelines for track performance evaluation established by the country, rail surface damage is inspected with the naked eye of engineers and simple measuring tools. With the recent enactment of the Track Diagnosis Act, a large budget has been invested and the volume of rail diagnosis is rapidly increasing, but it is difficult to secure the reliability of diagnosis results using labor-intensive visual inspection techniques. It is very important to discover defects in the rail surface through periodic track tours and visual inspection. However, evaluating the severity of defects on the rail surface based on the subjective judgment of the inspector has significant limitations in predicting damage inside the rail. In this study, the rail internal crack characteristics due to rail surface damage were studied. In field measurements, rail surface damage locations were selected, samples of various damage types were collected, and the rail surface damage status was evaluated. In indoor testing, we intend to analyze the correlation between rail surface defects and internal defects using a electron scanning microscope (SEM). To determine the crack growth rate of urban railway rails currently in use, the Gaussian probability density function was applied and analyzed.

Natural Frequency Analysis of Sleeper Floating Track System using Modal Test Technique (모달시험기법을 이용한 침목플로팅궤도의 고유진동수 분석)

  • Jung-Youl Choi
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.3
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    • pp.833-838
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    • 2024
  • The urban railway sleeper floating track(STEDEF) is a structure that structurally separates the sleepers and the concrete bed using sleeper boots and resilience pads to reduce vibration transmitted to the concrete bed. Recently, the resilience pads of sleeper floating tracks that have been in use for more than 20 years are deteriorating. Accordingly, in order to evaluate the performance of the resilience pad, a static spring stiffness test is being performed after extracting the resilience pad. This evaluation technique is performed after replacing the resilience pad in use. However, the track natural frequency can change depending on the resilience pad spring stiffness and the uplift and subsidence of the concrete bed. In this study, modal testing technique was used to evaluate the track natural frequency. For this purpose, the sleeper boots material, resilience pad spring stiffness, and track natural frequency according to concrete bed uplift and subsidence were measured using modal tests at a laboratory scale. It was analyzed that the natural frequency of the sleeper floating track was directly affected by changes in the spring stiffness of the resilience pad. In addition, the change in natural frequency due to the uplift and subsidence of the concrete bed was also found to be large. Therefore, it is believed that the modal test technique presented in this study can be used to evaluate the resilience pad deterioration and voided sleepers.