• Title/Summary/Keyword: Performance testing

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Establishment of Quantitative Method for Generic Drugs in Korea Pharmaceutical Codex Monograph (공정서 수재 의약품의 정량법 개선에 관한 연구)

  • Song, JaeYong;Jang, JinSeob;Jang, SeungEun;Kim, SunHoi;Kim, InKyu;Lee, GilBong;Lee, JeaMan;Kim, YongHee
    • YAKHAK HOEJI
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    • v.56 no.5
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    • pp.288-292
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    • 2012
  • The aim of the paper is to ameliorate old research methods of Korean Pharmaceutical Codex to adjust the newest scientistic level which is necessary to maintain quality of medical supplies effectively. After reviewing result of Establishment of Dissolution Specifications for Generic Drugs in Korea Pharmaceutical Codex Monograph, there are two items chosen for the methods - Establishment of Dissolution Specifications for Generic Drugs in Korea Pharmaceutical Codex Monograph which KFDA researched in 2010, arranged new measuring standard by having an experiment to set measuring method after obtaining each item. According to the result, The experiment includes a measuring method of two items; Nafronyl Oxalate Capsules, and Ticlopidine Hydrochloride Tablets. The research is ameliorated by research methods through several experiments such as High Performance Liquid Chromatography validation, preparing items, implement of trial-experiment and authentic experiment, and experiment on measuring method of regulations of Korea Pharmaceutical Codex. The experiments are taken opinions of experts in KFDA into consideration and wrote out a report of the new measuring method on each last item. The report is combined as each two experiment sections of analyzing method to maintain the quality on the basis of the research in 2010 on setting of dissolution specifications for oral solid dosage forms. The result of measuring method of medical supplies through modernizing trial method of oral solid dosage forms is available to be accurate. In conclusion, this study could contribute to promotion of public health by organizing a basis for safe and high quality of medical supplies in domestic market.

Experimental Verification of a Liquid Damper with Changeable Natural Frequency for Building Response Control (고유진동수 조절이 가능한 액체댐퍼의 건물응답 제어실험)

  • Kim, Dong-Ik;Min, Kyung-Won;Park, Ji-Hun;Kim, Jae-Keon;Hwang, Kyu-Seok;Gil, Yong-Sik
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.25 no.4
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    • pp.323-330
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    • 2012
  • This study deals with the experiments of liquid dampers with multi cells whose vertical tubes are divided into several square columns for easily changing natural frequencies. Shaking table test is performed to verify control effectiveness of the dampers which are installed on a building structure. To design liquid dampers, a 64-story building structure is reduced to a SDOF structure with 1/20 of similitude laws based on acceleration. The structure model is made up to adjust its mass and stiffness easily, with separate mass and drive parts. Mass parts indicate real structure's weights and drive parts indicate real structure's stiffness with springs and LM guides. Manufactured liquid damper has 18 cells and its natural frequency ranges are 0.65Hz to 0.81Hz. Shaking table test is carried out with one way excitation to compare with only accelerations of a large-scale structure and a structure installed with liquid dampers. Control performance of the liquid damper is expressed by the transfer function from shaking table accelerations to the large-scale structure ones. Testing results show that the liquid damper reduced a large-scale structure's response by tuned natural frequencies.

Inspection on the acoustic output of the focused extracorporeal focused shock wave therapeutic devices approved by MFDS (식약처에서 허가된 집속형 ESWT 치료기의 음향 출력 분석)

  • Choi, Min Joo;Jeon, Sung Joung;Kwon, Oh Bin;Lee, Min Young;Cho, Jin Sik;Kim, Han Soo;Maeng, Eun Ho
    • The Journal of the Acoustical Society of Korea
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    • v.39 no.4
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    • pp.303-317
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    • 2020
  • Extracorporeal Shock Wave Therapy (ESWT) is an innovative treatment in chronic musculoskeletal pain management and cardiovascular diseases. In this study, we surveyed the acoustic shock wave outputs from the domestically used focal type ESWT devices. The survey data were collected through 30 technical documents registered to the Ministry of Food and Drug Safety (MFDS), Rep. Korea. The results show that the focusing geometry varies largely, 5 mm to 65 mm in the focal length, 3 mm to 30 mm in focal width, and 4 mm to 108 mm in focal depth. The maximum positive pressure (P+) ranges from 7 MPa to 280 MPa, the focal Energy Flux Density (EFD) from 0.0035 mJ/㎟ to 35 mJ/㎟, and the energy per pulse (E) from 0.737 mJ to 80.86 mJ. All domestic PE-type (five) and one EM-type domestic devices included in the analysis of the correlation between P+ and EFD are shown to be far beyond the usual ranges and do not comply with expected correlation so that the reliability of their data was suspected. For the suspected, post-performance tests are required by a recognized testing agency. MFDS guidelines need to be revised so that the pass criteria for the shock wave acoustic outputs can be based on the clinical tests for indications.

Multi-copter Wind-tunnel Test (멀티콥터 풍동시험)

  • Hwang, SeungJae;Cho, TaeHwan;Kim, YangWon;Chung, JinDeog
    • Journal of Aerospace System Engineering
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    • v.11 no.6
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    • pp.10-16
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    • 2017
  • In order to improve the safety of the multi-copter, Korea Aerospace Research Institute (KARI) performed a wind-tunnel test using an octocopter with the maximum takeoff weight (MTOW) of 28 kg. The wind-tunnel test was performed with three different RPM ranges, 3,500, 4,500 and 5,500 rpm, and three different wind speeds, 3.5, 5 and 7 m/sec. The tested range of the angle of attacks was $-40^{\circ}$ to $20^{\circ}degree$ and ${\pm}90^{\circ}degree$. Vortex ring state (VRS) of the tested multi-copter was located around the vertical descending speed of 6 m/sec and the decrement of thrust was about 13 % at the time of testing. Compared with the single propeller wind-tunnel test result, the propeller efficiency of the octocopter dropped to 10 to 15% depending on the propeller RPM. It is hypothesized that the obtained aerodynamic characteristics by the wind-tunnel test will be used to improve the performance and wind resistance of the multi-copter.

An Importance Analysis of National Competency Standard for 4-year College Information Systems Development Curriculum (국가직무능력표준(NCS)의 4년제대학 정보시스템개발 교육과정을 위한 중요도분석연구)

  • Kim, Jae Kyung
    • Journal of Korea Society of Industrial Information Systems
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    • v.22 no.4
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    • pp.117-129
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    • 2017
  • The Purpose of this Study is to Identify the Learning Modules of the National Competency Standard (NCS) Related to the Information Systems Development Curriculum of 4-year Colleges, to Explore the Possibility of Applying NCS to the Curriculum, and to Examine Implications. The Importance of 26 Competency Units in the Applied SW Engineering of NCS was Compared by Area Experts Composed of 14 Information Systems Developers and Professors of 7 Universities who Teach Software Engineering Subjects Through the Hierarchical Analysis Process (AHP). The Results of the Study as Follows. First, the Relative Importance of the Competency Elements was in order of 'Confirming the Requirements', 'Checking the UI Requirements', 'Designing the Physical Data Repository', 'Testing Developer Integration', and 'Fixing Developer Defects'. Second, while the Entry and Intermediate Level Developer Group Determined that the Competency Elements Related to the IS Development Implementation Stage is more Important, the Advanced IS Developer Groups Consider the Competency Elements Related to the Theory-oriented Design Stage as Important Competency. In Addition, the Group of College Professors was Found to Choose all the Practical and Theoretical Competency Elements that Two Developers Groups Considered Important. Implications of the Study Suggested that the Job Performance Competence and Quality of Education Related to IS Development can be Enhanced.

Strength Characteristics on Sulfuric Acid Corrosion of Recycled PET Polymer Concrete with Different Fillers (충전재 종류에 따른 PET재활용 폴리머콘크리트의 황산부식에 대한 강도 특성)

  • Jo Byung-Wan;Shin Kyung-Chul;Park Seung-Kook
    • Journal of the Korea Concrete Institute
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    • v.17 no.4 s.88
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    • pp.499-504
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    • 2005
  • Polymer concrete shows excellent mechanical properties and chemical resistance compared with conventional normal cement concrete. The polymer concrete Is drawing a strong interest as high-performance materials in the construction industry Resins using recycled PET offer the possibility of a lower source cost of materials for making useful polymer concrete products. Also the recycling of PET in polymer concrete would help solve some of the solid waste problems Posed by plastics and save energy. An objective of this paper is to estimate the damage of sulfuric acid, through investigating recycled PET polymer concrete, immersed at sulfuric acid solution for 84 days. As a result of testing, recycled PET PC, used $CaCO_3$ as filler, makes a problem of appearance and strength if they are exposed for long term at corrosion environment. On the other hand, recycled PET PC, used fly-ash as filler, had less effect on decrease in weight and strength. Recycled PET PC is excellent chemical resistance, resulting in the role of unsaturated polyester resin which consists of polymer chain structure accomplishes bond of aggregates and filler strongly. Also, recycled PET PC, used fly-ash as filler, is stronger resistance of sulfuric acid corrosion than $CaCO_3$, because it is composed of $SiO_2$ and very strong glassy crystal structure. Therefore, recycled PET PC, used fly-ash as filler, is available under corrosion circumstances like sewer pipe or waste disposal plant.

Combustion of Diesel Particulate Matters under Mixed Catalyst System of Fuel-Borne Catalyst and Perovskite: Influence of Composition of Perovskite (La1-x A'xBO3: A' = K, Sr; 0 ≤ x ≤ 1; B = Fe, Cr, Mn) on Combustion Activity (Fuel-Borne Catalyst와 Perovskite로 구성된 복합촉매 시스템에 의한 디젤 탄소입자상 물질의 연소반응: 반응성능과 Perovskite 촉매조성 (La1-x A'xBO3: A' = K, Sr; 0 ≤ x ≤ 1; B = Fe, Cr, Mn)의 상관관계)

  • Lee, Dae-Won;Sung, Ju Young;Lee, Kwan-Young
    • Korean Chemical Engineering Research
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    • v.56 no.2
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    • pp.281-290
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    • 2018
  • As the internal combustion engine vehicles of high fuel efficiency and low emission are demanded, it becomes important to procure technologies for improving low-temperature performance of automotive catalyst systems. In this study, we showed that the combustion rate of diesel particulate matter is greatly enhanced at low temperature by applying fuel-borne catalyst and perovskite catalyst concurrently. It was tried to examine the correlation between elemental composition of perovskite catalyst and combustion activity of mixed catalyst system. To achieve this goal, we applied temperature-programmed oxidation technique in testing the combustion behavior of perovskite-mixed particulate matter bed which contained the element of fuel-borne catalyst or not. We tried to explain the synergetic action of two catalyst components by comparing the trends of concentrations of carbon dioxide and nitrogen oxide in temperature-programmed oxidation results.

English Vocabulary Learning Application Development Applying Forgetting Curve and Match Result Based Rating System (망각곡선과 대결 기반 순위 결정 시스템을 적용한 영어 단어 학습 어플리케이션 개발)

  • Youm, Kiho;Oh, Kyoungsu;Chun, Youngjae
    • Journal of Korea Game Society
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    • v.15 no.3
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    • pp.151-160
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    • 2015
  • This paper presents English vocabulary memorization system using forgetting curve to automatically adjust the vocabulary difficulty to match learner's level. Our system will decide the appropriate repetition cycle, depending on the number of memorizing words through the forgetting curve, then requires an iterative learning. No matter what learners know or do not know, words are reviewed. To save time by reviewing some words which have the highest probability that learners forget. And it provides vocabulary based on learner level, which makes learner maintain their interest and achievement. A general system provides vocabularies which difficulty matches with evaluated ones, or randomly provides some vocabularies without consideration of users' level. But we apply the "Glicko" system which is being used in the online chess game ranking system to adjust the vocabulary's difficulty. We utilize the system used in the one-by-one player system to our vocabulary-human system. As a result, learners's level and the vocabularies's difficulty is measured in the review process. Moreover it maximizes the performance of English vocabulary memorization by applying feedbacks from practice testing and distributed learning.

Improvement of Endoscopic Image using De-Interlacing Technique (De-Interlace 기법을 이용한 내시경 영상의 화질 개선)

  • 신동익;조민수;허수진
    • Journal of Biomedical Engineering Research
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    • v.19 no.5
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    • pp.469-476
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    • 1998
  • In the case of acquisition and displaying medical Images such as ultrasonography and endoscopy on VGA monitor of PC system, image degradation of tear-drop appears through scan conversion. In this study, we compare several methods which can solve this degradation and implement the hardware system that resolves this problem in real-time with PC. It is possible to represent high quality image display and real-time processing and acquisition with specific de-interlacing device and PCI bridge on our hardware system. Image quality is improved remarkably on our hardware system. It is implemented as PC-based system, so acquiring, saving images and describing text comment on those images and PACS networking can be easily implemented.metabolism. All images were spatially normalized to MNI standard PET template and smoothed with 16mm FWHM Gaussian kernel using SPM96. Mean count in cerebral region was normalized. The VOls for 34 cerebral regions were previously defined on the standard template and 17 different counts of mirrored regions to hemispheric midline were extracted from spatially normalized images. A three-layer feed-forward error back-propagation neural network classifier with 7 input nodes and 3 output nodes was used. The network was trained to interpret metabolic patterns and produce identical diagnoses with those of expert viewers. The performance of the neural network was optimized by testing with 5~40 nodes in hidden layer. Randomly selected 40 images from each group were used to train the network and the remainders were used to test the learned network. The optimized neural network gave a maximum agreement rate of 80.3% with expert viewers. It used 20 hidden nodes and was trained for 1508 epochs. Also, neural network gave agreement rates of 75~80% with 10 or 30 nodes in hidden layer. We conclude that artificial neural network performed as well as human experts and could be potentially useful as clinical decision support tool for the localization of epileptogenic zones.

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A Study of a Heat Flux Mapping Procedure to Overcome the Limitation of Heat Flux Gauges in Fire Tests (화재실험시 열유속 센서 사용의 단점을 보완한 Heat Flux Mapping Procedure에 관한 연구)

  • Choi, Keum-Ran
    • Journal of the Korean Society of Safety
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    • v.20 no.4 s.72
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    • pp.171-179
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    • 2005
  • It is essential to understand the role of wall lining materials when they are exposed to a fire from an ignition source. Full-scale test methods permit an assessment of the performance of a wall lining material. Fire growth models have been developed due to the costly expense associated with full-scale testing. The models require heat flux maps from the ignition burner flame as input data. Work to date was impeded by a lack of detailed spatial characterization of the heat flux maps due to the use of limited instrumentation. To increase the power of fire modeling, accurate and detailed heat flux maps from the ignition burner are essential. High level spatial resolution for surface temperature can be provided from an infrared camera. The objective of this study was to develop a heat flux mapping procedure for a room test burner flame to a wall configuration with surface temperature information taken from an infrared camera. A prototype experiment was performed using the ISO 9705 test burner to demonstrate the developed heat flux mapping procedure. The results of the experiment allow the heat flux and spatial resolutions of the method to be determined and compared to the methods currently available.