• Title/Summary/Keyword: Peptide vibration

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Performance Evaluation of Explosive Specific Bio-receptor Using QCM Sensing Platform for Resonance Frequency Shift Detection (공진점변화검출용 QCM 센싱플랫폼을 이용한 폭발물 특이적 바이오수용체 성능평가)

  • Lim, Si-Hyung;Jeong, Hyun-Jin
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.21 no.3
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    • pp.280-284
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    • 2011
  • The mass change during the molecular interaction between explosive specific bio-receptors and target molecules has been measured using quartz crystal microbalance(QCM), which has a mass change detection limit up to ~ng/$cm^2$. The environmental effect on the molecular interaction has been evaluated. In the liquid phase molecular interaction experiments, the high selectivity of the bio-receptor to DNT compared with toluene has been shown and the sensitivity for various concentrations of DNT has been demonstrated.

Interplay of the Intramolecular Water Vibrations and Hydrogen Bond in N-Methylacetamide-Water Complexes: Ab Initio Calculation Studies

  • Kim, Joo-Hee;Cho, Min-Haeng
    • Bulletin of the Korean Chemical Society
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    • v.24 no.8
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    • pp.1061-1068
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    • 2003
  • The correlation between the water and N-methylacetamide (NMA) intramolecular vibrational frequencies and the hydrogen-bond length in a variety of NMA-H₂O and NMA-D₂O complexes was investigated by carrying out ab initio calculations. As the hydrogen-bond length decreases, the frequencies of bending and stretching modes of the hydrogen-bonding water increases and decreases, respectively, and the amide I and II (III) mode frequencies of the NMA decreases and increases, respectively. In this paper, correlation maps among the amide (I, II, and III) modes of NMA and three intramolecular water modes are thus established, which in turn can be used as guidelines for interpreting two-dimensional vibrational spectra of aqueous NMA solutions.