• 한국임상약학회지
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• 제27권2호
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• pp.113-118
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• 2017

Objective: International institutes such as Global institute for Asthma(GINA), KAAACI(Republic of Korea), NHLBI(USA), BTS(UK) and JSA(Japan) have published guidelines for asthma treatment. The aim of this study was to compare the representatives' international guidelines of pharmacotherapy for pediatric asthma. Methods: The recommendations related to pharmacotherapy for pediatric asthma were extracted from the latest representatives' international guidelines, and comprehensive comparisons were conducted. Results: Major comparison outcomes between international guidelines were evaluated as follows: classification system on severity and pediatric age group, recommendation for inhaled corticosteroid dose, recommendation for pediatric age group of theophylline in mild asthma, and recommendation for pediatric age group of tiotropium in severe asthma. Clinical trials emphasized the adverse effects of theophylline, whereas tiotropium demonstrated beneficial actions for pediatric asthma. Therefore, theophylline was recommended for older patients with persistent asthma, and tiotropium was considered to be suitable for younger patients with severe asthma according to GINA guidelines. Conclusion: These findings address the requirement to harmonize international guidelines of pharmacotherapy in pediatric asthma. In addition, the findings suggest that KAAACI needs to update its pharmacotherapy guidelines of theophylline, tiotropium and other medicines recently approved.

• 부모자녀건강학회지
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• 제5권2호
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• pp.191-205
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• 2002

This study was conducted to provide the baseline data for preparing an educational program for mothers of pediatric asthma patients by identifying the knowledge about asthma, mother's educational demand and the perceived educational performance. This study used survey design. The subjects were chosen from the mothers whose children have received pediatric asthma treatment or who have admitted in the pediatric unit of major hospitals using selection criteria. The total number of subjects were 63 mothers. The data collection period was from May 1st, 2001 to April 17th, 2001. Instruments used for this study were knowledge examination, educational demand evaluation, and educational performance. The data were analysed using t-test, ANOVA with SPSS PC(Version 10.0). The results of this study were as follows. 1. Mean score of knowledge about pediatric asthma was 17.95, which suggests the mothers of children with asthma have a medium knowledge level. The highest grade was knowledge about treatment and follow management and the lowest grade was knowledge about diet. 2. Demand for education showed 4.23, which suggests the mothers of children with asthma have high educational demand. The highest score was about exercise and activity in daily life and the lowest score was medication. 3. Perceived educational performance score of themselves showed 2.40, which suggests the mothers of children with asthma thought that health team do not give enough education to them. The highest score was knowledge about pediatric asthma itself and the lowest score was exercise and activity in daily life. 4. Demand for education and perceived educational performance about pediatric asthma showed significant difference in all areas. 5. There were no statistically significant difference noted between general characteristics and degree of knowledge, educational demand and perceived educational performance about pediatric asthma. In conclusion, there needed a systematic educational program development for the mothers of children with asthma. Especially, an education program for mothers in the beginning period of pediatric asthma should be emphasized.

• 대한한방소아과학회지
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• 제29권2호
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• pp.49-58
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• 2015

Objectives Asthma is an allergic disease that frequently occurs in children. This study aims to research acupuncture and acupoint-application treatment of pediatric asthma. Methods We got 53,653 search results with searching word 'child' 'children' 'pediatric' 'juvenile' 'adolescence' 'baby' 'infant' 'asthma' in Pubmed and got 147 results among them with searching word 'acupuncture' 'acupoint application'. We selected 13 articles among them which were seem to be related to this study. We classified these studies according to the type of study, the treatment methods and treatment outcomes. Results There were few studies about acupuncture and acupoint application on pediatric asthma. According to current research, conducting acupuncture and acupoint application treatment on pediatric asthma patient is recommended. Especially, acupoint application and laser acupuncture treatment were important to consider as treatment options on pediatric asthma patients for non-invasive way and less painful to children. Conclusions For the study on acupuncture and acupoint application treatment in pediatric asthma, it is necessary that we conduct research on various merit of acupuncture. More clinical data would be needed to prove the effects of acupuncture and acupoint application treatment in pediatric asthma.

• 한국간호교육학회지
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• 제11권2호
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• pp.252-259
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• 2005

Purpose: Asthma is the most common chronic disease of childhood. It's important mother's caring for management of children with asthma. This study was to provide the evidenced data for preparing an educational program by identifying the knowledge level and educational demand about pediatric asthma of mothers of children with asthma. Method: The subjects were 91 mothers of children with asthma who admitted at 3 hospital in Busan. The data were collected through a self-reporting questionnaire from Feburary to May, 2005. The data was analyzed by SPSS 10.0 program. Results: The total mean percentage of correct answer of knowledge about pediatric asthma was 55.6% and the total mean $score{\pm}SD$ of educational demand about pediatric asthma was $4.40{\pm}0.50$. The knowledge level was statistically different by recurrence number(F=3.08, p=.049). There was not correlation between knowledge level and eucational demand. Conclusions: The mothers of children with asthma had a medium knowledge level and a high educational demand. Based on the results, mothers' knowledge is an important part of children with asthma management. Therefore nursing intervention program for mothers of children with asthma should be developed and the mothers should cope with asthma effectively.

• Tuberculosis and Respiratory Diseases
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• 제80권2호
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• pp.113-135
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• 2017

Asthma is traditionally regarded as a chronic airway disease, and recent literature proves its heterogeneity, based on distinctive clusters or phenotypes of asthma. In defining such asthma clusters, the nature of comorbidity among patients with asthma is poorly understood, by assuming no causal relationship between asthma and other comorbid conditions, including both communicable and noncommunicable diseases. However, emerging evidence suggests that the status of asthma significantly affects the increased susceptibility of the patient to both communicable and noncommunicable diseases. Specifically, the impact of asthma on susceptibility to noncommunicable diseases such as chronic systemic inflammatory diseases (e.g., rheumatoid arthritis), may provide an important insight into asthma as a disease with systemic inflammatory features, a conceptual understanding between asthma and asthma-related comorbidity, and the potential implications on the therapeutic and preventive interventions for patients with asthma. This review discusses the currently under-recognized clinical and immunological phenotypes of asthma; specifically, a higher risk of developing a systemic inflammatory disease such as rheumatoid arthritis and their implications, on the conceptual understanding and management of asthma. Our discussion is divided into three parts: literature summary on the relationship between asthma and the risk of rheumatoid arthritis; potential mechanisms underlying the association; and implications on asthma management and research.

• Clinical and Experimental Pediatrics
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• 제56권10호
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• pp.424-430
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• 2013

Exhaled nitric oxide (NO) has been extensively investigated as a noninvasive marker of airway inflammation in asthma. The increased NO expression induced by inflammatory mediators in airways can be monitored easily in exhaled air from asthmatic children. Based on the relationship between the increased NO expression and eosinophilic airway inflammation, fractional exhaled nitric oxide (FeNO) measurements become an important adjunct for the evaluation of asthma. In addition, the availability of portable devices makes it possible to measure FeNO more easily and frequently in the routine pediatric practice. Despite various confounding factors affecting its levels, FeNO can be applicable in diagnosing asthma, monitoring treatment response, evaluating asthma control, and predicting asthma exacerbations. Thus, although pulmonary function tests are the standard tools for objective measurements of asthmatic control, FeNO can broaden the way of asthma monitoring and supplement standard clinical asthma care guidelines.

• 대한한방소아과학회지
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• 제21권1호
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• pp.1-9
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• 2007

Objectives : The purpose of this study is to investigate oriental medical treatment of pediatric bronchial asthma. Method : Chinese medical journals which is about pediatric bronchial asthma were analyzed for a reference. Result : Oriental medical treatment can be classified into three ways; internal treatment, external treatment, and combination treatment which means combining with Chinese and Western ways of treatments. Conclusion : Oriental medical treatment of pediatric bronchial asthma is more effective therapy than Western's.

• 대한한방소아과학회지
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• 제29권3호
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• pp.1-11
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• 2015

Objectives : The purpose of this study is to analyze the trends in foreign clinical trials for pediatric asthma in complementary and alternative medicine (CAM). Methods : We reviewed 31 randomized controlled trials (RCT) for pediatric asthma treatment in CAM published from 2005 to 2015 in PubMed and analyzed their treatments, compounds of herbal medicines, acupoints, methods of assessment, and treatment results. Results : The treatments used in the studies were herbal medicines, acupuncture, acupoint application, breathing training, supplement, normocaloric diet, yoga, massage therapy, and art therapy. The frequently used herbs were Asari Herba Cum Radix (細辛). Ephedrae Herba (麻黃), Astragali Radix. The most common acupoints were Feishu (肺兪, BL13). The methods of assessment in pediatric asthma were symptom scale, questionnaire of Quality of Life, lung function test, laboratory studies, and medication usage. In 28 out of 31 studies, treatment group gets better than non-treated group. Conclusions : This study shows that CAM is effective in treating pediatric asthma. More clinical studies using objective outcome measures are needed to prove its efficacy clearly.

• 대한한방소아과학회지
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• 제37권4호
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• pp.70-90
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• 2023

Objective This study analyzed randomized clinical trials (RCTs) on pediatric asthma using traditional Chinese medicine (TCM) to determine its efficacy and safety. Methods We searched electronic databases in English, Chinese, Japanese, and Korean and evaluated 35 articles published up to December 28, 2022. Based on data from the literature, we analyzed treatments, results, composition of herbal medicine, frequency of medicinal herbs, and decoction. Results TCM for pediatric asthma was compared to supportive therapy, inhaled corticosteroids, and standardized treatments. Of the 35 studies, 32 showed that TCM treatments were effective in alleviating asthma symptoms. Furthermore, TCM treatment was considered safe compared to common asthma treatments. Among the TCM treatments for pediatric asthma, the most frequent decoctions were Gamisaganmahwangtang (加味射干麻黃湯) and Saganmahwangtang (射干麻黃湯). Ephedra Herba (麻黄), Armeniacae Semen (杏仁), Asiasari Radix et Rhizoma (細辛), Belamcandae Rhizoma (射干) were herbs that were frequently used for asthma in TCM decoctions. Conclusion This review showed that TCM is effective in treating pediatric asthma. More clinical RCTs are needed to confirm the efficacy and safety of TCM treatment.

• Clinical and Experimental Pediatrics
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• 제63권3호
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• pp.102-103
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• 2020