• PNF and Movement
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• 제18권3호
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• pp.305-313
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• 2020

Purpose: The aim of this study was to investigate the relationship between a functional evaluation model and the Fugl-Meyer assessment (FMA) scale in evaluating the upper extremities of stroke patients Methods: Thirty-eight stroke patients were evaluated using the FMA and performed reaching and grasping motions using a three-dimensional motion analysis (Qquas 1 series, Qualisys AB, Sweden). The participants sat on a chair with a backrest. The position of the cup was located at a distance of 80% to the front arm length. The markers were attached to the sternum, acromion, elbow lateral epicondyle, ulnar styloid process, three metacarpal heads, and the distal phalanges of the thumb and index finger. The variables of the correlation between the functional evaluation model and the FMA scale were analyzed. Multiple regression (stepwise) was used to investigate the effect of the kinematic variables. Results: A significant negative correlation was found between the movement time (p < 0.05), movement unit (p < 0.05), and trunk displacement values (p < 0.05) in the FMA total scores, while a positive correlation was found between the peak velocity (p < 0.05) and maximum grip aperture values (p < 0.05). As a result of the multiple regression analysis, the most significant factor was the movement unit, followed by the general movement assessment and trunk displacement. The explained FMA total score value was 62%. Conclusion: This study presents a new functional evaluation model for assessing the reaching and grasping ability of stroke patients. The factors of the proposed functional evaluation model showed significant correlations with the FMA scale scores and confirmed that the new functional evaluation model explained the FMA by 67%. This suggests a new functional evaluation model for reaching and grasping stroke patients.

• 대한토목학회논문집
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• 제41권6호
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• pp.707-714
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• 2021

회전교차로 주변 지체 유발의 중요한 원인 중 하나는 교통량 불균형 상태라 할 수 있다. 그러나 국내연구에서는 교통량 불균형을 규명하는 연구에 있어 상충교통량보다 진입교통량 비율에 집중하는 경향이 있다. 또한 회전교차로 건설 시 지체와 관련한 인접 교차로와의 적정거리에 관한 연구도 미흡하다고 할 수 있다. 따라서 본 연구에서는 실제 교통량 불균형이 발생하고 신호 교차로와 인접한 이천시 가좌로 회전교차로를 대상으로 교통량 불균형 및 적정거리 산정 연구를 SIDRA를 활용하여 분석하였다. 그 결과 가좌로 회전교차로는 상충교통량 측면에서 불균형 상태로 인해 회전교차로의 지체가 발생하였고 신호교차로와 거리가 850 m일 때부터 모든 접근로에서 대기행렬이 소멸하는 것으로 나타났다.

• Tuberculosis and Respiratory Diseases
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• 제85권2호
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• pp.175-184
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• 2022

Background: Post-tuberculosis (TB) sequelae is a commonly encountered clinical entity, especially in high TB burden countries. This may represent chronic anatomic sequelae of previously treated TB, with frequent symptomatic presentation. This pilot study was aimed to investigate the pulmonary functions and systemic inflammatory markers in patients with post-TB sequelae (PTBS) and to compare them with post-TB without sequelae (PTBWS) participants and healthy controls. Methods: A total of 30 participants were enrolled, PTBS (n=10), PTBWS (n=10), and healthy controls (n=10). Pulmonary function tests included spirometry and measurement of airway impedance by impulse oscillometry. Serum levels of matrix metalloproteinase (MMP)-1, transforming growth factor-β, and interferon-γ were estimated. Results: Slow vital capacity (SVC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV₁), FEV₁/FVC, and peak expiratory flow were significantly lower in PTBS as compared to controls. SVC and FEV₁ were significantly less in PTBS as compared to PTBWS. Total airway impedance (Z₅), total airway resistance (R₅), central airway resistance (R₂₀), area of reactance (Ax), and resonant frequency (Fres) were significantly higher and respiratory reactance at 5 and 20 Hz (X₅, X₂₀) were significantly lower in PTBS as compared to PTBWS. Spirometry parameters correlated with impulse oscillometry parameters in PTBS. Serum MMP-1 level was significantly higher in PTBS as compared to other groups. Conclusion: Significant pulmonary function impairment was observed in PTBS, and raised serum MMP-1 levels compared with PTBWS and healthy controls. Follow-up pulmonary function testing is recommended after treatment of TB for early diagnosis and treatment of PTBS.

• Animal Bioscience
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• 제35권11호
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• pp.1656-1665
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• 2022

Objective: Water buffalo, an important domestic animal in tropical and subtropical regions, play an important role in agricultural economy. It is an important source for milk, meat, horns, skin, and draft power, especially its rich milk that is the great source of cream, butter, yogurt, and many cheeses. In recent years, long noncoding RNAs (lncRNAs) have been reported to play pivotal roles in many biological processes. Previous studies for the mammary gland development of water buffalo mainly focus on protein coding genes. However, lncRNAs of water buffalo remain poorly understood, and the regulation relationship between mammary gland development/milk production traits and lncRNA expression is also unclear. Methods: Here, we sequenced 22 samples of the milk somatic cells from three lactation stages and integrated the current annotation and identified 7,962 lncRNA genes. Results: By comparing the lncRNA genes of the water buffalo in the early, peak, and late different lactation stages, we found that lncRNA gene lnc-bbug14207 displayed significantly different expression between early and late lactation stages. And lnc-bbug14207 may regulate neighboring milk fat globule-EGF factor 8 (MFG-E8) and hyaluronan and proteoglycan link protein 3 (HAPLN3) protein coding genes, which are vital for mammary gland development. Conclusion: This study provides the first genome-wide identification of water buffalo lncRNAs and unveils the potential lncRNAs that impact mammary gland development.

• 운동영양학회지
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• 제25권1호
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• pp.42-55
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• 2021

[Purpose] This study investigated the effects of marine phytoplankton supplementation (Oceanix®, Tetraselmis chuii) on 1) maximal isometric strength and immune function in healthy humans following a oneweek high-intensity resistance-training program and 2) the proinflammatory cytokine response to exercise in a rat model. [Methods] In the human trial, 22 healthy male and female participants were randomly divided into marine phytoplankton and placebo groups. Following baseline testing, participants underwent a 14-day supplement loading phase before completing five consecutive days of intense resistance training. In the rat model, rats were randomly divided into four groups (n=7 per condition): (i) control, (ii) exercise, (iii) exercise + marine phytoplankton (2.55 mg/kg/day), or (iv) exercise + marine phytoplankton (5.1 mg/kg/day). Rats in the exercising groups performed treadmill exercise 5 days per week for 6 weeks. [Results] In the human model, marine phytoplankton prevented significant declines in the isometric peak rate of force development compared to placebo. Additionally, salivary immunoglobulin A concentration was significantly lower following the resistance training protocol in the placebo group but not in the marine phytoplankton group. Marine phytoplankton in exercising rats decreased intramuscular levels and serum concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) and intramuscular concentrations of malondialdehyde. [Conclusion] Marine phytoplankton prevented decrements in indices of functional exercise recovery and immune function. Mechanistically, these outcomes could be prompted by modulating the oxidative stress and proinflammatory cytokine response to exercise.

• Design & Manufacturing
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• 제17권1호
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• pp.56-63
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• 2023

In this study, the vibration signal of the mold was measured and analyzed to monitor the process information and characteristics during the press molding process. A necklace-type picture frame mold was used for press molding, and the vibration signal was measured by GY-61 acceleration sensor module attached to the surface of the upper (movable) mold base. The change of the vibration signal of the mold according to press speed was analyzed. As a result, the vibration signal had a large change at five sections: "Holder contact", "Punch contact and start of pressing", "End of pressing", "Mold open", and "Demolding". The time difference between "Punch contact and start of pressing" and "End of pressing" means the pressing time which is the actual time the material is molded under pressing pressure. The time intervals for each section, represented by the time interval between "Holder contact" and "Punch contact and start of pressing", can be used to compare and evaluate the press speed applied to the process. By comparing the vibration signals at 60 rpm and 90 rpm, the amplitude at the section of "Punch contact and start of pressing" increased as the press speed increased. This result means that as the press speed increases, more force and pressure is applied to the material. Also, the peak values of the other sections were found to increase as the press speed increased. It was found that the pressing time, the time interval between "Punch contact and start of pressing" and "End of pressing", decreases as the pressing speed increases. Similarly, press speed factor, the time interval between "Holder contact", and "Punch contact and start of pressing", is found to be shorter. Therefore, based on the result of this study, the pressing time, press speed, pressing(punching) pressure of each cycle can be monitored by measuring the vibration signal of the mold. Also, it was confirmed that the level and trend of process information and characterization can be evaluated as the change of the mold vibration during press molding.

• 대한이식학회지
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• 제28권3호
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• pp.154-159
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• 2014

Background: Lung transplantation (LTx) is a life-saving treatment for patients with end-stage lung disease; however, the shortage of donor lungs has been a major limiting factor to increasing the number of LTx. Growing experience following LTx using donor lungs after cardiac death (DCD) has been promising, although concerns remain. The purpose of this study was to develop a DCD lung harvest model using an ex vivo lung perfusion (EVLP) system and to assess the function of presumably damaged lungs harvested from the DCD donor in pigs. Methods: The 40 kg pigs were randomly divided into the control group with no ischemic lung injury (n=5) and the study group (n=5), which had 1 hour of warm ischemic lung injury after cardiac arrest. Harvested lungs were placed in the EVLP circuit and oxygen capacities (OC), pulmonary vascular resistance (PVR), and peak airway pressure (PAP) were evaluated every hour for 4 hours. At the end of EVLP, specimens were excised for pathologic review and wet/dry ratio. Results: No statistically significant difference in OC (P=0.353), PVR (P=0.951), and PAP (P=0.651) was observed in both groups. Lung injury severity score (control group vs. study group: 0.700±0.303 vs. 0.870±0.130; P=0.230) and wet/dry ratio (control group vs. study group: 5.89±0.97 vs. 6.20±0.57; P=0.560) also showed no statistically significant difference between the groups. Conclusions: The function of DCD lungs assessed using EVLP showed no difference from that of control lungs without ischemic injury; therefore, utilization of DCD lungs can be a new option to decrease the number of deaths on the waiting list.

• 한국지반공학회논문집
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• 제22권4호
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• pp.85-94
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• 2006

본 논문에서는 고결(Cementation)에 의한 모래의 비배수 거동변화를 파악하기 위하여 석고를 고결유발제로 사용한 시료를 조성한 후 등방삼축시험(CIU)을 실시하였으며, 상대밀도 및 고결정도에 따른 거동 양상을 분석하였다. 연구결과 모래의 고결은 항복강도$(q_y)$, 항복시 할선탄성계수$(E_y)$, 첨두마찰각$(\Phi_p)$의 상당한 증가를 유발시키고, 상대밀도보다 모래의 거동에 더 큰 영향을 끼치는 것으로 확인되었다. 그러나 고결결합이 파괴된 이후, 모래의 거동은 고결보다는 상대밀도의 영향을 더 크게 받는 것으로 나타났다. 또한 고결결합에 의한 압축성 감소는 간극수압 발생율을 감소시켜 고결모래의 유효응력 경로가 미고결 모래의 전응력 경로쪽으로 편향되어 발생하였다. 고결결합이 파괴되기 전에는 다일레이션 경향이 감소하지만, 결합이 파괴된 후에는 미고결 모래보다 더 큰 다일레이션 경향이 유발되었다.

• 한국지반공학회논문집
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• 제24권4호
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• pp.67-78
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• 2008

본 연구에서는 시멘트의 고결효과를 정량적으로 파악하기 위하여 낙동강하상모래와 소량의 포틀랜드시멘트를 혼합하여 고결된 모래에 대하여 일축압축시험 및 배수조건과 비배수 조건의 삼축압축시험을 수행하였다. 시멘트혼합율의 증가에 따라 첨두강도 및 탄성계수는 증가하였고 시멘트의 결합력에 의하여 다일레이션 및 과잉간극수압이 억제되었으나 시멘트 결합력의 파괴 후 증가된 모래입자크기에 의하여 증가하였다. 그리고 배수조건의 응력-변형률 곡선은 연화거동이 나타났지만 비배수조건에서는 증가된 부(-)의 과잉간극수압에 의한 유효응력의 증가로 경화거동을 나타냈다. 각 조건에 대한 강도증가량의 예측을 위하여 선형을 가정한 다중회귀분석을 실시한 결과 제시된 경험식의 결정계수는 $0.81{\sim}0.91$로 나타나 신뢰성이 높은 것으로 평가되었으며 건조밀도의 경우 고결된 모래의 입도조건을 동시에 고려할 수 있어 고결된 모래의 강도를 결정하는데 중요한 변수로 분석되었다.

• 한국컴퓨터정보학회논문지
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• 제14권2호
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• pp.37-44
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• 2009

본 논문에서는 실시간 지진감시 시스템의 필수 조건이 되는 PGA데이터의 실시간 전송성능을 향상시킬 수 있는 효과적인 방식을 제안한다. 현재 전국에 120개 이상의 지진 관측소가 설치되었으며, 지진 재해에 대한 사회적 관심이 높아짐에 따라 향후 더욱 많은 지진 관측소들이 설치될 예정이다. 실시간 지진감시 시스템은 각 지진 관측소의 가속도 데이터를 이용하여 만든 PGA데이터를 이용하여 지진감시를 수행한다. 실시간 지진감시 시스템 구축을 위해 효율적인 PGA데이터 송 수신이 필수적이다. 제안 데이터 전송 방식은 국내에 설치된 지진 관측소를 각각 유일한 ID로 관리하고 패킷 헤더에 각 ID별로 1 bit를 할당하여 데이터 포함여부를 표시한다. 기존의 전송 방식보다 많은 관측소의 데이터를 처리할 수 있고, 데이터 전송 시 발생하는 데이터 유실율도 최소화한다. 제안한 데이터 전송 방식의 성능을 검증하기 위하여 약 91,000개의 패킷에 대한 처리 시간 및 데이터 유실을 등을 분석하였다. 실험 결과로써 제안한 전송 방식은 기존 전송 방식에 비해 약 50%정도의 처리시간 증가를 보이고 있으나 데이터 유실율은 기존 전송 방식에 비하여 87.5%가 감소된 것으로 확인되었다.