• 한국미생물·생명공학회지
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• 제38권3호
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• pp.278-282
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• 2010

1) 며느리배꼽의 항균활성 측정결과, S. aureus, P. acnes, 에 대한 ethyl acetate 분획의 MIC는 각각 0.25%, 0.25%로 큰 항균활성을 나타내었으며, 천연 방부제, 항균제로서 역할이 충분히 기대된다. 2) 며느리배꼽 추출물의 ethyl acetate 분획의 TLC는 5개의 띠(PP1, PP2, PP3, PP4, PP5)로 분리가 되었고, 그 중에서 농도가 가장 진한 것은 $R_f$ 값이 0.32인 PP4로 나타났다. 3) 며느리배꼽 추출물 중 ethyl acetate 분획의 HPLC 크로마토그램은 검출파장 320nm에서 8개의 peak를 나타내었고, peak 1은 caffeic acid, peak 2는 quercetin-3-o-glucuronide, peak 3은 isoquercitrin, peak 5는 quercetin, peak 6는 apigenin으로, peak 7은 kaempferol 임을 확인하였다. 4) 며느리배꼽 추출물의 aglycone 분획의 TLC는 3개의 띠(PPA1, PPA2, PPA3)로 분리가 되었고, 그 중에서 농도가 가장 진한 것은 $R_f$ 값이 0.45인 PPA3로 나타났다. 5) 며느리배꼽 추출물 중 aglycone 분획의 HPLC 크로마토그램은 검출파장 260 nm에서 3개의 peak를 나타내었고, peak 1은 caffeic acid, 높이가 가장 높은 peak 2는 quercetin 그리고 peak 3은 kaempferol임을 확인하였다. 이상의 결과들로부터 며느리배꼽 추출물의 강력한 항산화 성분과 항균 활성으로부터 며느리배꼽 추출물의 항산화, 항균 화장품으로의 응용 가능성을 시사한다.

• 한국정보과학회논문지:정보통신
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• 제27권3호
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• pp.301-314
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• 2000

World Wide Web(이하 웹)은 저렴한 가격과 다양하고 흥미 있는 정보를 쉽고 간편하게 찾아볼 수 있다는 장점으로 웹의 사용자는 하루가 다르게 증가되고 있으며 웹의 사용자의 증가와 함께 웹을 통해 전달되는 데이터 즉, 웹 문서, 그림, 멀티미디어 데이터 등의 크기 또한 빠르게 증가되고 있다. 웹 트래픽을 위한 네트워크 대역폭의 사용량을 살펴보면 사용자들의 요청이 많은 peak periods에는 대부분의 대역폭을 사용하고 있고, off-peak periods에는 사용하지 않는 대역폭이 존재한다. 지금까지 네트워크의 대역폭 소비량을 감소시키고, 검색 지연시간을 줄이기 위해 많은 연구가 이루어졌고 그 해결방안 중 하나가 웹 캐싱이다. 그러나, 웹 캐싱을 사용하더라도 peak periods 동안에는 네트워크 대역폭의 사용량을 감소시키기에는 한계가 있으며 off-peak periods에 여유 있는 네트워크 대역폭을 효율적으로 사용할 수 업사. 본 논문에서는 네트워크 대역폭을 균형 있게 사용하기 위해 캐싱 서버(SQUID)를 기반으로 하는 웹 프리페칭(Web prefetching)기법을 제안한다. 24시간 동안의 웹 사용 상황을 분석하여, 가장 많이 사용되면서 다음 24시간 내에 유효기간을 초과하는 웹 객체를 프리페칭하는 방법을 사용한다. 제안된 웹 프리페칭 기법은 peak periods 동안 요청되리라 예상되는 웹 객체를 off-peak periods 동안 남는 대역폭을 이용하여 미리 캐싱 서버에 가져다 놓은 방법으로써 많은 디스크 용량을 요구하지 않으면서도 캐시 객체 히트율을 높일 수 있다. 또한 사용자들의 웹 접근 패턴을 기반으로 하기 때문에 프리페칭된 웹 객체에 대하여 높은 객체 히트율을 보인다. 본 논문에서 소개한 기법의 유효성 시뮬레이션을 통해서 증명하였다. 시뮬레이션 결과는 본 논문에서 제안된 프리페칭 기법이 효율적으로 peak bandwidth를 줄일 수 있다는 것을 나타낸다.

• 분석과학
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• 제16권4호
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• pp.269-276
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• 2003

새로운 종류의 벗김전압전류법, 즉 전도된 촉매 벗김전압전류법 ($IC_tSV$)을 소개한다. 염산 용액에서 로듐-포름알데히드 착물은 역주사 동안에 환원전류 봉우리 즉 전도된 촉매수소 봉우리가 생긴다. 이 전도된 봉우리의 특징을 조사하고 이 봉우리를 분석 봉우리로 이용하여 결정한 검출한계는 $1.2{\times}10^{-10}M$ (축적시간 50초)이었다. 최적 실험 조건은 0.015% (W/V) HCHO-0.42 M HCl, 농축전위 -1.1 V, 주사속도 100 mV/s이다.

• Molecules and Cells
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• 제38권6호
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• pp.496-505
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• 2015

A variant peak was detected in the analysis of RP-HPLC of rHu-EPO, which has about 7% relative content. Fractions of the main and the variant peaks were pooled separately and further analyzed to identify the molecular structure of the variant peak. Total mass analysis for each peak fraction using ESI-TOF MS shows differences in molecular mass. The fraction of the main peak tends to result in higher molecular masses than the fraction of the variant. The detected masses for the variant are about 600-1000 Da smaller than those for the main peak. Peptide mapping analysis for each peak fraction using Asp-N and Glu-C shows differences in O-glycopeptide profiles at Ser126. The O-glycopeptides were not detected in the fraction of the variant. It is concluded that the variant peak is non-O-glycosylated rHu-EPO and the main peak is fully O-glycosylated rHu-EPO at Ser126.

• The Journal of Korean Physical Therapy
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• 제14권1호
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• pp.169-176
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• 2002

The purpose of this study were to measured peak torque of lumbar extensor at various degrees and to compare with the choronic low back pain patients and healthy subjects back extensor peak torque. Research subject are fifty choronic low back pain patients and fifty healthy subjects are Dong-a university hospital visited to 2000, January since 1999, august none lumbosacral traumal past history and neurologic disorder that is twenty generation, thirty generation, forty generation, fifty generation, sixty generation in healthy subjects and twenty generation, thirty generation, forty generation, fifty generation, sixty generation in cause choronic low back pain patients. The result were as follows. 1. There were each generation choronic low back pain patients and healthy subjects back extensor peak torque are consideration (p<.05). 2. Twenty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 3. Thirty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 4. Forty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<;.05). 5. Fifty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05). 6. Sixty generation was all degree of angle in lumbar extention peak torque in choronic low back pain patients back extensor are lower than healthy subjects(p<.05).

• Journal of Pharmaceutical Investigation
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• 제40권3호
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• pp.193-200
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• 2010

The objective of this study was to investigate the effects of sample preparation, HPLC conditions and peak measurement methods upon determining progesterone content of poly-d,l-lactide-co-glycolide microspheres. A series of the microspheres with different formulations was first prepared. To determine their actual drug contents, the microspheres were dissolved in tetrahydrofuran and diluted with various amounts of methanol to precipitate the polymer. After removal of polymeric precipitates, the filtrates were subject to HPLC analysis under versatile experimental conditions. Interestingly, the composition of a sample solution (e.g., the ratio of methanol to tetrahydrofuran) affected the magnitudes of both peak fronting and peak broadening of progesterone. Its peak became broader and more asymmetrical at lower methanol:tetrahydrofuran ratios. Furthermore, its peak height was influenced by the proportion of tetrahydrofuran in a sample solution. Such problems encountered with tetrahydrofuran were exacerbated when a larger volume of the sample solution was injected onto an analytical column. Under our experimental conditions a peak area measurement provided more accurate and reliable determination of progesterone content in various microspheres than a peak height determination. Optimizing the composition of a sample solution, HPLC chromatographic conditions and peak analysis methods was a prerequisite to an accurate determination of progesterone encapsulated within microspheres.

• 전기학회논문지
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• 제67권1호
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• pp.96-102
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• 2018

For efficient operating strategy of electric power system, forecasting of daily peak electric load is an important but difficult problem. Therefore a daily peak electric load forecasting system using a neural network and fuzzy system is presented in this paper. First, original peak load data is interpolated in order to overcome the shortage of data for effective prediction. Next, the prediction of peak load using these interpolated data as input is performed in parallel by a neural network predictor and a fuzzy predictor. The neural network predictor shows better performance at drastic change of peak load, while the fuzzy predictor yields better prediction results in gradual changes. Finally, the superior one of two predictors is selected by the rules based on rough sets at every prediction time. To verify the effectiveness of the proposed method, the computer simulation is performed on peak load data in 2015 provided by KPX.

• 한국미생물·생명공학회지
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• 제14권6호
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• pp.467-471
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• 1986

Fusarium moniliforme으로부터 순모세포벽 분해효소를 생산하고 분리, 정제하여 효소특성 및 protoplast 제조실험을 하였다. Ammonium nitrate를 0.2％ 첨가한 Baker's yeast 배지에서 7일간 진탕배양으로 효소를 생산한 후 Ammonium sulfate로 분획하고 Sephadex(G-100) column chromatography하여 세개의 peak를 얻었다 첫 번째 peak는 proteolytic, lytic activity 및 laminarin 분해력가를 보였으며, 두 번째 Peak는 lytic activity와 laminarin 분해력가를 동시에 가지고 있었으며, 세 번째 peak는 lytic activity만을 가지고 있었다. 분리된 세개의 peak를 혼합하였을때 개개의 peak보다 훨씬 높은 역가을 나타내어 상승효과를 보였고 또한 환원제에 의한 효소력가의 상승효과도 있었다. protoplast 수율은 99.2％정도였다

• 천문학회보
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• 제42권2호
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• pp.82.3-83
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• 2017

We investigate the relationships between the peak fluxes of 18 solar energetic particle (SEP) events and associated coronal mass ejection (CME) 3D parameters (speed, angular width, and separation angle) obtained from SOHO, STEREO-A and/or B for the period from 2010 August to 2013 June. We apply the STEREO CME Analysis Tool (StereoCAT) to the SEP-associated CMEs to obtain 3D speeds and 3D angular widths. The separation angles are determined as the longitudinal angle between flaring regions and magnetic footpoints of the spacecraft, which are calculated by the assumption of Parker spiral field. The main results are as follows. 1) We find that the dependence of the SEP peak fluxes on CME 3D speed from multi-spacecraft is similar to that on 2D CME speed. 2) There is a positive correlation between SEP peak flux and 3D angular width from multi-spacecraft, which is much more evident than the relationship between SEP peak flux and 2D angular width. 3) There is a noticeable anti-correlation (r=-0.62) between SEP peak flux and separation angle. 4) The multiple regression method between SEP peak fluxes and CME parameters shows that the longitudinal separation angle is the most important parameter, and the CME 3D speed is secondary on SEP peak flux.

• Journal of Mechanical Science and Technology
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• 제15권7호
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• pp.1002-1012
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• 2001

The work reported here is an extensive study of tendon response to multiple cyclic tests including 3% constant peak strain level test (A-type test), 3% constant peak strain level test with two rest periods (B-type test), and 3∼4% different peak strain level test (C-type test). A sufficient number of specimens were tested at each type of the test to statistically evaluate many changes in response during testing and differences in response between each type of the test. In cyclic tests, there were decreses (relaxations) in the peak stresses and hysteresis, increases in the slack strains, and during lower peak strain level (3%) cyclic block after higher peak strain level (4%) cyclic block in the C-type tests. Considering the results of this study and those of the other study of multiple cyclic tests with rest periods by Hubbard and Chun, 1985, recovery phenomena during the rest periods occurred predominantly at the beginning of the rest periods. Consistently in both studies, the effects of rest periods were small and transient compared to the effects of the cyclic extensions. The recovery with cycles at lower peak strain level (3%) after higher peak strain level (4%) in the C-type test has not been previously documented. This recovery seems to be a natural phenomena in tissue behavior so that collagenous structures recover during periods of decreased demand.