• Acta Via Serica
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• v.3 no.2
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• pp.161-180
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• 2018

Pax Sinica is a historiographical term, modeled after the original phrase Pax Romana. It refers, in Latin, to a Chinese-provided peace which in turn is used to describe an era of peace in East Asia sustained by Chinese hegemony. In historical terms, both the Pax Sinica of the Eastern hemisphere through Han China and the Pax Romana of the Western hemisphere through Rome signified a trans-regional order based on rules and regulations. This orderly world of the Pax Sinica generated a number of positive results such as the intensification of travel, ever-expanding trade relations, an increase in the overall living standards of the populace, the proliferation of cities, and a demographic upsurge in Eurasia along the ancient Silk Road. During this period, China was the dominant civilization not only in the Eastern hemisphere but also in the Middle hemisphere due to its political, economic, military and cultural influence. This paper aims to reintroduce this historiographical term to elucidate the recent Chinese initiatives in Eurasia along the Silk Road to facilitate the integration and connectivity of the continent.

• The Korea Journal of Herbology
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• v.35 no.3
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• pp.9-16
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• 2020

Objectives : Sarcopenia is a disease that leads to a decrease in skeletal muscle, and the importance of prevention and treatment thereof is increasing in an aging society. However, there is a definite limitation of exercise therapy for sarcopenia, and thus, there is an urgent need for a pharmacologic research to the treatment of sarcopenia. Methods : 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay was performed to confirm the antioxidant efficacy of water extract of Lacca Sinica Exsiccata (WELSE). To determine the effect of WELSE on myoblast activity, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay was performed. To confirm the effect of WELSE on the differentiation of myoblast into myotubes, protein expression levels of myosin heavy chain 3 (Myh3) and paired box 3/7 (pax3/7) were confirmed by immunoblot analysis. In addition, immunofluorescence microscopy was performed to confirm the effect on myotube formation of WELSE. Results : It was confirmed that WELSE had high antioxidant activity and showed no cytotoxicity to myoblast up to 200 ㎍/㎖ concentration. Myoblast was treated with WELSE at a concentration of 100 ㎍/㎖ and differentiated for 5 days. The expression of Myh3, which forms myotubes, was promoted and the morphology of myotubes was changed and Increasing the thickness. Conclusions : In this paper, we confirmed the excellent antioxidant efficacy of WELSE and positive effects on muscle differentiation and myotube formation. These results suggest valuable as a material for pharmaceutical research on the prevention and treatment of sarcopenia.