• Archives of Pharmacal Research
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• v.17 no.6
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• pp.470-475
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• 1994

The butanol extract of paulownia tomentosa stem showed antibacterial activity against staphyl ococcus aureus (SG511, 285 and 503), Streptococcus pyogenes (A308 and A77) and Streptococcus farcium MD8b etc. The most active compound of the extractg was identified to be campneoside I, which had a minimal inhibitory concentration(MIC) of $150{\;}{\mu}g/ml$ against Strptococcus and Staphylococcus species. From such antibacterial activity, the methoxy group of campneoside I was posulated to be the essential element for the antibacterial activity.

• Microbiology and Biotechnology Letters
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• v.50 no.2
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• pp.310-318
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• 2022

The fruits of Paulownia tomentosa (Thunb.) (PT) Steud. have been reported to exert a variety of biological activities. A previous study confirmed that compounds isolated from PT fruits (PTF) exerted anti-inflammatory effects on TNF-α-stimulated airway epithelial cells. However, there is no report on the protective effects of PTF on acute lung injury (ALI). Here, we examined the ameliorative effects of PTF in an experimental animal model of lipopolysaccharide (LPS)-induced ALI. In ALI mice, increased levels of inflammatory cell influx were confirmed in the lungs of mice, and an increase of microphage numbers, TNF-α, IL-6 and MCP-1 production and protein content were detected in mouse bronchoalveolar lavage fluid. However, these increases were significantly reversed with PTF pretreatment. In addition, PTF inhibited the increased expression of iNOS and COX-2 in the lungs of ALI mice. Furthermore, the upregulation of MAPK and NF-κB activation was decreased in the lungs of ALI mice by PTF. In the in vitro experiment, PTF pretreatment exerted an anti-inflammatory effect by inhibiting the secretion of nitric oxide, TNF-α and IL-6 in LPS-stimulated RAW264.7 macrophages. Collectively, these results indicated that PTF has ameliorative effects on airway inflammation in an experimental animal model of ALI.

• Journal of the Korean Wood Science and Technology
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• v.46 no.5
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• pp.511-526
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• 2018

Effects of heat treatment on the characteristics of Royal paulownia (Paulownia tometosa) wood were investigated. The results were compared with those of Suwon silver poplar (Populus tementiglandulosa) and Korean red pine (Pinus densiflora) woods. The wood samples of the three species were treated at $160^{\circ}C$, $180^{\circ}C$, $200^{\circ}C$ and $220^{\circ}C$ in an electric furnace for 2 hours. The changes of color, density, mass loss, and relative crystallinity were investigated before and after heat treatment. The lightness ($L^*$) decreased rapidly from $200^{\circ}C$ in all species. There were no change in red-green chromaticity($a^*$) and yellow-blue chromaticity($b^*$) of Royal paulownia and poplar woods with increasing temperature. Whereas, yellow-blue chromaticity($b^*$) of Korean red pine wood decreased sharply from $200^{\circ}C$. Royal paulownia wood showed appreciable color change(${\Delta}E^*$) after heat treatment above $180^{\circ}C$. Poplar and pine woods, however, presented significant color change from $160^{\circ}C$. Color change of the three wood species increased rapidly with increasing temperature. Mass loss of the three wood species by heat treatment was the highest in the Royal paulownia wood and the lowest in the pine wood. Mass loss and relative crystallinity increased and density decreased slightly with increasing temperature. Consequently, it is revealed that Royal paulownia wood showed considerable differences in the temperature of color change, weight loss and change of relative crystallinity compared to the other wood species.

• Journal of Korean Society of Forest Science
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• v.49 no.1
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• pp.6-10
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• 1980

The witches' broom disease of Paulownia tomentosa (Thunb.) Steud with which mycoplasmalike organisms are associated is widespread throughout Korea and poses serious threat to the cultivation of paulownia. Attempt was made to investigate the feasibility of field control of the disease with oxytetracycline hydrochloride (OTC). A total of 84 paulownia trees (6 year-old, DBH: 10-15cm) exhibiting severe symptoms of witches' broom were selected and treated during March to September. Solution of 1-10g of OTC dissolved in 0.1­2.0 of water was transfused into infected trees with gravity flow method from a dark-brown colored plastic reservoir (11 volume) through plastic tubes (1.2m long) connected to 2-4 holes (5 mm in diameter and 4-5cm in depth) bored in the basal part of the tree trunks (Fig. 1 and 2). Of 60 diseased paulownia trees injected with 2g of OTC in 0.1-2.0l of water during May to September, 1979, 58 trees resulted in complete remission of symptom development and resumption of healthy new growth at least up to September, 1980 when the last observation of the effect of OTC treatment for this experiment was made. The rest of two trees were dead probably due to too severe infection. Of 24 paulownia trees treated in March and April, 1979 complete remission of symptom development was obtained with 8 trees, and nine trees were partially prevented from symptom development in the following season. The remaining 7 trees were dead due to failure in uptake of OTC and partly because the trees were in too far advanced stage of infection. Application of highly concentrated solution of 2g of OTC dissolved in 0.1-0.2l of water per tree was just as effective as the 2g/1-2l treatment. Injection of 2g/1-2l required 3-4 days while treatment of 2g/0.1-0.2l reduced the time for injecting one tree down to less than 24 hrs. The result of this experiment demonstrates that basal trunk injection of 2g OTC/0.1-0.2l/tree is feasible for field control of paulownia witches' broom, provided that tree injection is performed in actively growing season (May-September) and at the initial stage of disease development.