• The Korean Journal of Pharmacology
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• v.18 no.1
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• pp.55-63
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• 1982

Lipid peroxidation is the reaction of oxidative deterioration of polyunsaturated lipids and this peroxidation involves the direct reaction of oxygen and lipid to form free radical intermediates, which can lead to autocatalysis. As results of the extensive studies on the lipid peroxidation by many authors, the relationship between lipid peroxidation and the drug metabolizing system as well as the actions of free radicals on the peroxidation was reasonably well known. For a long time, the mechanism of hepatotoxicity of $CCl_4$ was not clearly understood. However, it is now quite well established that $CCl_4$ is activated in vivo to a free radical which is a highly reactive molecule. Therefore, lipid peroxidation which induces the reduction of cytochrome P-450 and aminopyrine demethylase activity is known as decisive event of $CCl_4$ hepatotoxicity. On the other hand, it was also reported that singlet molecular oxygen produces lipid peroxidation in liver microsomes. In this study the effects of benzoyl peroxide on the lipid peroxidation and drug-metabolizing enzyme were examined. Benzoyl peroxide mixed with starch and phosphates etc. is usually used as a food additive for flour bleaching and maturing purpose because of its oxidative property. Albino rats were used for the experimental animals. Benzoyl peroxide was suspended in soybean oil and sesame oil and administered intraperitoneally or orally. TBA value and aminopyrine demethylase activity were determined in liver microsomal fraction and serum. The results were summerized as following. 1) Body weights of animals administered benzoyl peroxide suspension were decreased while that of oil administered group were increased. 2) The activity of aminopyrine demethylase was generally decreased in animals administered oil suspension of benzoyl peroxide. Furthermore, the marked reduction of the enzyme activity was observed in animals administered benzoyl peroxide intraperitoneally. 3) Generally, microsomal TBA values as well as serum TBA were significantly elevated in benzoyl peroxide group in comparison with the control group. However, the more remarkable increase of serum TBA than microsomal TBA was observed in animals administered orally for 6 days. 4) Specifically, the changing pattern of TBA value was notable in serum rather than in liver microsome by intraperitoneal administration of benzoyl peroxide.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.511-520
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• 2020

Owing to global warming, heat waves have become stronger in the summer, and research on improving the thermal environment of green spaces, such as urban parks, is being conducted. On the other hand, studies on improving the urban thermal environment, which is changing due to the greening pattern and the intensity of the wind, are still insufficient. This study analyzed the temperature of the green spaces on campus to understand the factors affecting the temperature changes. After investigating the covering condition and planting form of the site, factors, such as temperature, humidity, wind direction, wind speed, and illuminance, were measured. The most influential factors on the temperature distribution are evapotranspiration and wind - induced heat transfer. The other major factors affecting the temperature change were the type of cover, wind velocity/wind direction, type of planting, shade / solar irradiance. In the type of cover, the plant was classified as low temperature, and the asphalt pavement was classified as high temperature. In wind speed, instantaneous temperature was reduced by 1.2 ℃ in southern wind, 0.7 ℃ in the westerly wind, 0.4 ℃ in the north wind and 0.5 ℃ in the east wind when a wind of 3.5m/s or more was blown.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7403-7415
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• 2014

This study points out a problem that the vehicle rotation area provided in a dead-end parking lot for apartment blocks is misused as unreasonable parking places but accordingly, the edge parking spaces are rarely used for parking. Therefore, this study aims to establish a parking design standard to improve the parking convenience and land-use efficiency by investigating the real parking behaviors and problems identified in the study area, multiple apartment blocks in Haeundae-gu, Busan. This study calculated two simple linear regression models for two mutually exclusive factors, such as the parking convenience and land-use efficiency, respectively, and specified a trade-off point that optimizes both factors. The study results found that parking convenience and land-use efficiency can be improved by not only changing the misused vehicle rotation area to normal parking spaces depending on the usage pattern, but also by increasing the width of the edge parking spaces from 2.3m to 2.6m. Finally, this study suggests two parking design cases for more realistic design applications by considering the parking environment in the dead-end parking lot for apartment blocks.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.682-692
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• 2007

This study presents an automatic system to predict parturition time in the crated sows. The system relies on ultrasonic transducers mounted from above along the length of the crate. Using a 40 kHz time of flight (TOF) single envelope wave, the momentary distances between the sensors are measured. Therefore, the local momentary height of the sow and the momentary posture, i.e. standing posture (SDP), kneeling posture (KP), sitting posture (STP) and lateral lying posture (LLP) are determined. Crated sows change their postures from standing to lying and vice versa which follows a characteristic pattern. As parturition approaches, sows exhibit uneasiness, restlessness and the stand up sequence (SUS, the posture transition from LLP to SDP) rate increases because of labor pains. In time series, the SUS rate demonstrates a peak and it happens approximately 0-12 h before parturition. In this paper, the basic parturition threshold value method (BPTVM) and the same hour method (SHM) are proposed for predicting parturition, both of which are based on the SUS rate. The BPTVM mainly detects the peak of the SUS rate. As the SUS rate exceeds the threshold value, the parturition becomes predictable. Moreover, the SHM calculates the difference in the SUS rates between a particular time of day and the corresponding time of the preceding day. Compared to the BPTVM, the SHM can eliminate the circadian rhythm of the SUS rate influenced by feeding behavior. Using the SHM the parturition can be approximately predicted within hours. In an attempt to define the threshold parameters of predicting parturition, a data set with 32 sows of the SUS rate are used to estimate assumable predicting probability. The results show the assumable probability of the parturition prediction within 9 h is 96.9% for the SHM and 84.4% for the BPTVM. Moreover, the SHM can even reach a 75% probability of prediction within three hours of parturition. We conclude that the SHM is more accurate and is more useful for parturition time prediction. When parturition is detected, the proposed algorithm generates a warning signal which can inform human personnel to protect the mother and newborn piglets.

• Journal of Veterinary Clinics
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• v.18 no.2
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• pp.124-132
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• 2001

The purpose of this study is to know whether single layer continuous connell suture is an acceptable alternative to simple interrupted approximating suture for end-to-end intestinal anastomosis in dogs. Fourteen mixed-breed dogs weighing 2 to 5 kg were allotted to group treated with simple interrupted approximating suture (Group I) and group treated with single layer continuous Connell suture (Group II), each of 7 dogs. All dogs in each suture pattern were compared with time for total operation ad suture elapsed for intestines to anastomose, clinical signs, changing of pre-and postoperative luminal size, status of feces, adhesion at anastomotic site for 14 days after operation. Time for total operation and suture time for intestinal anastomosis were none significant between Group I and Group II, although those in Group II was about 3 minutes shorter than those in Group I, respectively. Group I spent average 47.08${\pm}$11.10 minutes on total operation, 20.97${\pm}$5.54 minutes on suture time for intestinal anastomosis and Group II spent average 44.74${\pm}$7.77 minutes, 17.73${\pm}$3.05 minutes, respectively. All dogs were no special differences in vitality, vomiting, appetite between Group I and Group II for 14 days after operation. All dogs, except one dog in Group I, had showed normal vitality and appetite since 6~8 days after operation. Initial return of fecal passage showed in all dogs before 6 days after operation and thereafter most dogs showed normal feces. According to results, it was thought that all dogs with normal vitality and appetite before 8 days had showed good prognosis. There were no changes of intestinal luminal size in 2 dogs performed Group In and one dog performed Group II between at operation and 14 days after operation. Narrowing rate of intestinal lumen in Group I was average 9.3% of the normal diameter, whereas in Group II, 9.5% of normal diameter. In complications after operation, only one dog in Group I showed intestinal intussusception but the others didn't. Length of adhesion was measured between intestinal anastomotic site and omental graft. Length of adhesion in dogs performed Group II was mostly shorter than that of Group I. Adhesion with proximate intestines occurred in five dogs, which consisted of 3 dogs performed Group I and 2 dogs performed Group II. Concurrently, they had a great length of adhesion between anastomotic site and omental graft. There were no great differences between Group I and Group II about speed of operation, clinical signs, complications such as leakage and stricture. And all dogs performed intestinal anastomosis showed good clinical condition and prognosis. In conclusion, Single layer continuous Connell suture can safely perform an intestinal anastomosis and be an alternative of simple interrupted approximating suture in aspect of speed clinically.

• Journal of Cadastre & Land InformatiX
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• v.47 no.1
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• pp.127-142
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• 2017

The purpose of this study is to examine the status of urbanization of Namyangju-Si from 2001 till 2008, analyze the correlation of the change of surrounding land use according to the change of accessibility and analyze the correlation of the change of land use. Based on the result from correlation analysis, I simulated from the view point of interactions between agents of land use and transportation accessibility by using MAS. I tried to forecast, based on space, the change of surrounding land use caused by the change of accessibility. I conducted landscape analysis by using a land registration map. Also, I conducted GIS analysis statistical analysis simulation analysis of traffic data, land use data in order to analyze the correlation of the change of surrounding land use according to the change of accessibility. I could find out a certain pattern that new roads and railroads causes the within 500m adjacent land to change into urban land use, which led me to construct a system through which land use changing phenomenon can be expected according to the change of accessibility. It is expected that it can make the best use of selecting the location where new transportation facilities are constructed.

• Journal of the Korean Dietetic Association
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• v.6 no.2
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• pp.125-135
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• 2000

Hypertension is a well-known degenerative disease whose prevalence rate increases with age. Management of high blood pressure is a critical concern in preventive strategies to reduce the morbidity and mortality for cardiovascular disease. The purpose of this study was to examine the dietary characteristics of hypertensive program participants, and to establish strategies based on their nutritional needs. Hypertensive patients were enrolled in the program in a public health center or in a local elderly center, at Suwon, in 1999-2000. Trained dietitians interviewed 62 enrollees(24-hour recall) and related variables. Mean body mass index of the subjects was 25.0kg/m². 30.7% of the subjects had a family history of hypertension. The majority of them ate regularly and partook of all available side dishes. They consumed grains and vegetables regularly, but seldom ate dairy products or food prepared with oil. Male enrollees frequently consumed more processed food and animal fat than did female enrollees(p<0.05). An analysis of the percentage of RDA(Recommended Dietary Allowances of Korea 1995) showed that but for ascorbic acid, enrollees consumed nutrients below the RDA. The food group intake pattern was not diverse, thus only 8.1% of enrollees consumed all food groups in a day. An analysis of eating attitude showed that 64.5% of enrollees always added salt to beef soup. Male enrollees showed low food-related self-efficacy compared to female enrollees, especially with reference to reduction of instant food intake(p<0.01), increase in vegetable intake(p<0.01), reduction of monosodium glutamate(MSG) intake(p<0.01). and not overeating(p<0.05). Their perceived barriers for participating in hypertension nutrition programs included lack of time, program necessity non-recognition, and program comprehension difficulty. These results suggest that nutrition education program necessity non-recognition, and program comprehension difficulty. These results suggest that nutrition education programs for community hypertensive patients should focus on increasing participant consumption of foods, expecially dairy products, and desirable eating attitudes. It also suggests that the program should consider should consider encouraging self-efficacy in changing eating behavior.

• Journal of Ecology and Environment
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• v.29 no.3
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• pp.219-225
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• 2006

To study song themes and variation of Yellow-throated Bunting, we obtained and analyzed recordings from 45 males breeding in 16 deciduous forests of 6 provinces. We classified the 3,245 songs into a total of 164 song themes and 1,024 song variants according to the identification on the base of difference(lexicon) in 640 syllable compositions. Males had one to six song themes and averaged 3.5 themes. No males shared an identical song theme. Males had $5{\sim}14$ syllables (ave. 9.4) in one song theme and males increased effectively their repertoire size by changing syllable composition (i.e. adding, deleting, or substituting one or more syllables) in a single song theme. The number of variants averaged 5.1 (range 1 to 31) per song theme. Individual variability was highest in the terminal elements of the song. In PCA, the 16 populations are clearly separated on Co. I based on shared syllable and on Co. II based on unique syllable. Similarity of songs based on shared syllables by distance coefficients, showed a pattern of concordance with geography. Pairwise similarity declined with increasing distance among recording sites. 16 different geographical regions by the syllable were divided in UPGMA tree.

• Strategy21
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• s.43
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• pp.5-28
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• 2018

The tensions between the U.S and China, which form the two pillars of the G2 era, seem to have persisted even after the Trump administration inaugurated. The strong confrontation between the two in recent foreign security issues may drive to develop an inadvertent military conflict, and it is high likely to occur in the maritime are. The purpose of this study is not only to analyze the balance of modernized naval forces in the PLAN through naval strategy changes and weapons system modernization trend, but also to predict the impact of the geographical proximity difference on the balance of naval forces in the disputed areas. It examined the impact of distance and geography on naval power by assessing the modernization pattern of the PLAN and capabilities in the context of two scenarios at different distances from China by 2020: one centered on Taiwan and the other on the Spratly Islands. The PLAN's strategy had impact on operational concept and forces construction. First, from the viewpoint of operation operational concept, it can be seen that the passive defense is changing into active defense. Second, in terms of power construction, it can threaten the surface and submarines of U.S power from a distance. And they generated follow three features; The ocean is not the focus of Chinese submarines, Horizontal and vertical expansion of Chinese naval vessels, The improvement of the suppression ability as the Chinese naval modernization ratio increases. The strength of the PLAN is dominant over the U.S in terms of reserves, and it can complement the qualitative deterioration by utilizing nearby bases in the vicinity of the mainland, such as the Taiwan Strait. However, due to the shortage of aircraft carriers, there is a possibility that it will take some time to secure the advantage of air and ocean in the amphibious operation. Therefore, as the dispute is prolonged, China may fail to achieve its original goal. In addition, the lack of cutting edge Commanding Ships may bring to weaken the C2 capabilities. At results, it is expected that PLAN will not be able to have a superiority in the short term due to lagging behind U.S advanced technology. Nevertheless, PLAN has strengthened its naval power through modernization sufficiently and it is highly likely to use force. Especially, it is more likely in the region where the naval power operation like the Taiwan Strait is possible with the almost equality to that of the United States. China will continue to use its naval forces to achieve a rapid and decisive victory over U.S in the close area from the land.

• Journal of the Korean Geographical Society
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• v.42 no.4
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• pp.506-525
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• 2007

Incision into bedrock channel is the primary control of landform evolution, but research into bedrock incision process stagnated for long time. Due to the scaling problem of the application of results from flume studies to bedrock channel, there is a strong need to simulate the bedrock incision process with more realistic models. As a part of investigation into controls of bedrock channel incision, three-dimensional changes of rock surface with abrasion was investigated with physical modelling. 18 rock plates were abraded with various sediment particle size and sediment load and abraded surfaces of the plates were scanned with high resolution 3-D scanner. To identify the spatial pattern of erosion of the rock plates, various methods were used. There was no synthetic or holistic method that showed all features of bedrock plate produced by abrasion, so each plate was analyzed using some available methods. Contour maps, shaded relief maps and profiles show that abrasion concentrated on the centre of plate (cross profile) and upstream and downstream edges (longitudinal profile) and eroded area extended inwards. It also found that the cracks and boundaries of forming materials easily eroded than other parts. Changing patterns of surface roughness were investigated with profiles, regression analysis and spectral analysis. Majority of plates showed decrease in small-scale roughness, but it depends on microstructures of the plates rather than general hardness or other factors. SEM inspection results supported this idea.