• Journal of Chest Surgery
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• 제25권2호
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• pp.194-199
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• 1992

Two patients with congenital bronchoesophageal fistula were treated with surgical division. The first case was a 56-year-old female patient complaining of aggravated coughing, fever and chest pain since 10 days before the visit. The above symptoms were mild and occurred intermittently since 17 years ago. After the fistula was confirmed on the eso-phagogram, it was treated with coil embolization. The coil had dislodged and couldn`t be found two months later on follow up chest film. The patient underwent a surgical division of the fistula and has been in good condition The bronchoesophageal fistula belongs to type II in Braimbridge`s classification. The second case was a 5 year-old-female patient who suffered with cough intermittently since 2 years old and had history of recurrent pneumonia in infancy. An esophagogram revealed a fistula between the esophagus and the right lower lobe of the lung. An aortogram showed an abnormal systemic arterial supply to the right lower lobe of the lung. The sequestrated rigth lower lobe was resected and the fistula was divided. This case may be the first case of type IV bronchoesophageal fistula in Korea. This case also had good operative result.

• Journal of Korean Neurosurgical Society
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• 제46권3호
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• pp.273-276
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• 2009

A 54-year-old man experienced injury to the second finger of his left hand due to damage from a paintball gun shot 8 years prior, and the metacarpo-phalangeal joint was amputated. He gradually developed mechanical allodynia and burning pain, and there were trophic changes of the thenar muscle and he reported coldness on his left hand and forearm. A neuroma was found on the left second common digital nerve and was removed, but his symptoms continued despite various conservative treatments including a morphine infusion pump on his left arm. We therefore attempted median nerve stimulation to treat the chronic pain. The procedure was performed in two stages. The first procedure involved exposure of the median nerve on the mid-humerus level and placing of the electrode. The trial stimulation lasted for 7 days and the patient's symptoms improved. The second procedure involved implantation of a pulse generator on the left subclavian area. The mechanical allodynia and pain relief score, based on the visual analogue scale, decreased from 9 before surgery to 4 after surgery. The patient's activity improved markedly, but trophic changes and vasomotor symptom recovered only moderately. In conclusion, median nerve stimulation can improve chronic pain from complex regional pain syndrome type II.

• KSBB Journal
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• 제20권1호
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• pp.1-11
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• 2005

Recently, there has been extremely active in the research of stem cell biology. Stem cells have excellent potential for being the ultimate source of transplantable cells for many different tissues. Researchers hope to use stem cells to repair or replace diseased or damaged organs, leading to new treatments for human disorders that are currently incurable, including diabetes, spinal cord injury and brain diseases. There are primary sources of stem cells like embryonic stem cells and adult stem cells. Stem cells from embryos were known to give rise to every type of cell. However, embryonic stem cells still have a lot of disadvantages. First, transplanted cells sometimes grow into tumors. Second, the human embryonic stem cells that are available for research would be rejected by a patient's immune system. Tissue-matched transplants could be made by either creating a bank of stem cells from more human embryos, or by cloning a patient's DNA into existing stem cells to customize them. However, this is laborious and ethically contentious. These problems could be overcome by using adult stem cells, taken from a patient, that are treated to remove problems and then put back. Nevertheless, some researchers do not convince that adult stem cells could, like embryonic ones, make every tissue type. Human stem cell research holds enormous potential for contributing to our understanding of fundamental human biology. In this review, we discuss the recent progress in stem cell research and the future therapeutic applications.

• Archives of Plastic Surgery
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• 제38권5호
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• pp.683-686
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• 2011

Purpose: Craniosynostosis of three or more cranial sutures was not common. "Mercedes Benz pattern," named by Moore1 was a rare form of craniosynostosis and had an atypical pattern of premature closure of cranial suture. It was not reported in Republic of Korea. We report this case with literature review. Methods: A 13-months-old male patient visited our clinic due to exophthalmos. He showed normal developmental course. Other neurological tests were normal but he was Crouzon syndrome patient. CT scans showed bilateral lambdoid and posterior sagittal sutures were fused and the length of the skull was extended. Cranioplasty with pi craniotomy & Barrel-Stave osteotomy and recombination of the bone flap was performed. Results: The patient was discharged after post operative 10 days without any complications. In follow up visit after 2.7 years, he was in good state without recurrence and functional abnormality of skull. Conclusion: This was the first case of Mercedes Benz pattern craniosynostosis with Crouzon syndrome in Korea. This type of craniosynostosis has to be considered differently from single type of craniosynostosis or typical syndromic craniosynostosis clinically and surgically.

• 대한한방내과학회지
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• 제40권3호
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• pp.541-550
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• 2019

Objective: The aim of this clinical study was to describe the case of a patient who experienced chronic diarrhea related to seasonal changes that improved with herbal medicine treatment. Methods: A patient with diarrhea and globus hystericus was treated following treatment with Hoehyangbanchong-san-hap-Ukgan-san and Gamisachil-tang. A defecation and urination diary, the Bristol Stool Form Scale, and the Visual Analog Scale (VAS) were used to evaluate the effectiveness of this treatment. Results: During treatment, the patient's Bristol Stool Form Scale score changed from Type 7 to Type 4, and the VAS score was significantly decreased. The symptoms of diarrhea and globus hystericus almost subsided. Conclusion: In this case, Korean traditional herbal medicine reduced the clinical symptoms of diarrhea and globus hystericus.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권5호
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• pp.479-486
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• 2019

Progressive familial intrahepatic cholestasis (PFIC) is a group of severe genetic disorders, inherited in an autosomal recessive manner, causing cholestasis of hepatocellular origin, later progressing to biliary cirrhosis and liver failure. This is the first report of PFIC type 1 with novel compound heterozygous mutations in Korea. The patient was presented with intrahepatic cholestasis, a normal level of serum ${\gamma}-glutamyl$ transferase, steatorrhea, and growth failure. Genetic testing of this patient revealed novel compound heterozygous mutations (p.Glu585Ter and p.Leu749Pro) in the ATP8B1 gene. After a liver transplantation at age 19 months, the patient developed severe post-transplant steatohepatitis.

• 대한한방내과학회지
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• 제42권4호
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• pp.718-726
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• 2021

This study presents a case of add-on traditional Korean medical treatments in a 77-year-old male patient with uncontrolled type 2 diabetes mellitus with conventional oral hypoglycemic agents. Chief complaints were uncontrolled glucose level and weight loss. The patient was treated with electroacupuncture (on ST36, CV4, and CV12), herbal medication, and lifestyle advice. The conventional oral hypoglycemic medications were maintained. After 12 weeks, the glycated hemoglobin A1c (HbA1c) decreased from 11.0% to 8.4%. There were significant abnormalities in the liver function and renal function tests, but no adverse event was reported. Further studies are needed to confirm the findings of this case.

• 기본간호학회지
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• 제3권1호
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• pp.37-49
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• 1996

The Purposes of this study were to understand the types of appellations used by nurses and doctors for patients in a hospital and to analyze satisfaction and reason about appellation for patient. This would enable us to provide basic data on culturally suitable appellations for admitted patients. 454 patients at K University hospital in Seoul were subjects for this study. Subjects were interviewed individually using a questionnair and frequency $X^2-test$. Results are as follows. 1. The most frequently used type of appellations in hospitals was '-ssi ; -sir' used by 88.1% of the nurses and 83.9% of the doctors. About 3 quaters of the medical staff used '-ssi' while none used job position. 2. 93.2% of the patients were satisfied with the appellations used by nurses and 93.0% of the patients were satisfied with the appellations used by the doctors 43.7% didn't think appellations were important and 44.3% thought it natural to use the appellation. The most satisfactory form of appellation used by nurses was '-ssi' to 93.3% of patients. All were satisfied with '-nim ; -sir', '-teacher' and there was no statistically significance. On the other hand, the level of satisfaction and the appellation used by doctors showed a relationship($X^2=19.72$, p=.000). Every patient was satisfied with '-nim' and '-teacher' but 19.9% were dissatisfied with the others of appellations. 3. Most patients preferred to be called '-ssi' by nurses(77.3%) and doctors(78.7%) respectively. The dominant reason being accuracy(45.8%), naturalness(33.9%) for nurses and 43.8% and 45.4% respectively for doctors. 4. The relationship between the type of appellations requested of nurses and general characteristics showed that age($X^2=83.91%$ p=.000), level of education($X^2=33.35$ p=.000), and occupation($X^2=38.22$ p=.033) were related to the type of appellation. The type of appellation requested of doctors was related to the age($X^2=72.56$ p=.000), level of education($X^2=30.01$ p=.000), and occupation($X^2$=42.90 p=.010). Generally, '-ssi' was requested of doctors and nurses, but lower age group or higher age group(over 61), those in elementary schools or elementary school graduates snd students preferred being called by their first names or grandfather, grandmother. From the results above, we can see that the most general type of appellation used for patients by the medical staff is '-ssi' and most patients were satisfied with the appellation but, the reason being that such appellations were accepted without concern. This shows that most are not adequately satisfied with the appellation. Only a small number of people use '-nim' and '-teacher' but is the preferred and frequently used types of appellation. Therfore, a continuous research of appellations used for patients with patients using '-nim' and an investigation with nurses' opinions of appellations for patients as the subject are required.

• 대한소아신경학회지
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• 제25권3호
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• pp.200-203
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• 2017

척수소뇌실조는 임상적으로 다양하게 나타나는 보통염색체 우성신경변성 (혹은 퇴행성) 질환군으로서, 소뇌의 들과 날의 경로를 분열시켜 소뇌 실조를 일으키는 것으로 알려져 있다. 전형적인 임상증상은 30에서 40대에 발현되기 시작하고, 보행실조, 불분명 발음, 시력 이상, 사지의 조화운동 불능, 안구 움직임 제한, 인지 장애 등 다양한 증상의 조합을 특징으로 한다. 본 증례의 환아에서는 exome sequencing을 통하여 SPTBN2 (p.Glu1251Gln)의 새로운 이형접합 돌연변이를 발견하였으며 이것이 SCA5의 원인으로 밝혀졌다. 증례의 환아는 3년 5개월 때 발달지연을 주소로 본원에 내원하였다. 발달지연을 평가하기 위해 베일리 발달 검사에서 모든 영역에서 현저한 지연이 확인되었다. 본원 내원 1년 전 시행한 뇌자기공명영상에서 백샐질형성장애와 약간의 소뇌 위축이 보였다. 잠재적인 유전질환을 의심하여 진단 목적으로 전체엑솜염기서열분석을 시행하였고 결과적으로 SPTBN2의 새로운 이형접합 돌연변이 (p.Glu1251Gln) 가 SCA5의 원인 돌연변이로 사료된다. 척수소뇌실조에서 유전자의 역할을 명확하게 규명하기 위해서는 전체엑솜염기서열 분석을 포함한 다양한 방법을 통한 유전자 연구가 필요할 것으로 사료된다.

• 한국보건간호학회지
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• 제34권3호
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• pp.473-489
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• 2020

Purpose: This study investigated the patient safety culture (PSC), the perception of importance on patient safety management (PIPSM) and the patient safety management activities (PSMA) of care workers in nursing homes. This was a descriptive study that attempted to provide basic data for the patient safety education program of care workers. Methods: Data were collected using questionnaires and interviews from July 1 to 31 in 2020. One hundred and seventy-four care workers participated in quantitative research. The collected data were analyzed by the SPSS/WIN 25.0 program using descriptive statistics, t-test, ANOVA, Bonferroni, and Pearson's correlation. The qualitative data were collected through semi-structured, audio-recorded interviews with six representatives and six care workers from six nursing homes. Content analysis was performed to analyze the data. Results: Positive correlations were observed between PSC and PIPSM, and between PIPSM and PIPSM. Care workers' experience in patient safety management was in the following six categories: "Safety accident risk factors", "Type of safety accidents", "How to prevent safety accidents", "Effective safety management education", "Emphasis on occupational ethics of care workers", and "Needs for standard protocol" Conclusion: These findings indicate that considering the care workers' age and facility size, nurses should enhance patient safety education for care workers and establish a management activity system.