• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.2
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• pp.27-40
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• 2008

Background : In spite of the predominant of the theory of Pathogenesis, the method of Pathogenesis classification is depending on the doctor's clinical trials because od the lack of the objective test criteria. Methods and Results : This study is trying to improve the objectiveness of classification using a new statistical method, decision tree. Decision tree method -a classification technique in the statistical analysis- was used to analyze the result of pathogenesis questionnaire instead of using discriminant analysis. As a result, 10 among 38 pathogenesis questionnaire was selected as important questions and 12 terminal nodes was built to classify the pathogenesis. Conclusions : Using only 10 questions shown in the result of decision tree, we can classify and interpret the pathogenesis easily and effectively.

• Journal of Digestive Cancer Reports
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• v.7 no.1
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• pp.8-12
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• 2019

Despite its declining incidence, gastric cancer is globally, still, the third most common cause of cancer-related mortality. Gastric cancer is a heterogeneous disease with diverse pathogenesis and molecular backgrounds. Therefore several systems have been proposed to aid in the classification of gastric adenocarcinoma based on the macroscopic, microscopic and anatomical features of the tumor. However, these classifications did not reflect the pathogenesis of the disease. Recently, genomic analysis has identified several subtypes of gastric adenocarcinoma and a detailed understanding of the molecular biology behind the neoplastic phenotype is possible to develop of more effective therapies. We will describe the existing various classification of gastric cancer and the recently introduced molecular biology and immunological classification.

• Journal of Yeungnam Medical Science
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• v.28 no.1
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• pp.1-12
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• 2011

Primary liver carcinomas have classified classified into hepatocellular carcinoma, cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma (CHC). CHC is a tumor containing unequivocal, intimately mixed elements of both hepatocellular carcinoma and cholangiocarcinoma. It forms a small but significant proportion of primary liver carcinomas. The origin and pathogenesis of CHC have not been well established. According to the 2010 WHO classification, CHCs are categorized into 2 groups: the classical type and a subtype with stem cell features. This review describes recent progress in pathology and classification of CHC.

• Hip & pelvis
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• v.35 no.3
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• pp.147-156
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• 2023

Osteonecrosis of the femoral head (ONFH), a condition characterized by the presence of a necrotic bone lesion in the femoral head, is caused by a disruption in the blood supply. Its occurrence is more common in young and middle-aged adults and it is the main reason for performance of total hip arthroplasty in this age group. Its incidence is increasing along with increased use of glucocorticoids for management of adjuvant therapy for treatment of leukemia as well as organ transplantation and other myelogenous diseases. Current information on etiology and pathogenesis, as well as natural history, stage system, and treatments is provided in this review. A description of the Association Research Circulation Osseous (ARCO) criteria for classification of glucocorticoids-and alcohol-associated ONFH, 2019 ARCO staging system, and 2021 ARCO classification using computed tomography for the early stages of ONFH is also provided.

• Advances in Traditional Medicine
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• v.7 no.5
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• pp.447-458
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• 2008

This paper reviews the historic origin and traits of the classification system used in current Korean herbology textbooks. By reassessing its value, it proposes the most relevant path for future revisions and supplementations. Through an evaluation of the history of the modern style of classification in terms of its efficacy and statistic analysis of the distribution of individual herbs in each category, this paper shows how the classification systems of Korean herbology textbooks were influenced by contemporary Chinese herbology, particularly that of the Cheong [淸] Dynasty. An examination of the academic background, strengths and weaknesses of each classification system demonstrates the need for future research on classification systems to concentrate on resolving the following issues: how well the setting and composition of each classification system reflects reality, and how closely it is connected to related sciences such as etiology and pathogenesis, prescriptionology, and diagnosis.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2009.04a
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• pp.127-133
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• 2009

Cardiomyopathies were previously defined as "an idiopathic myocardial disease that is not secondary to any other type of congenital/acquired heart disease or systemic diseases." With increasing understanding of etiology and pathogenesis in human medicine, the difference between cardiomyopathy and specific heart muscle disease has become indistinct. Cardiomyopathies are now classified by the dominant pathophysiology or, if possible, by etiological/pathogenetic factors. The American Heart Association recently advocated the following new definition of cardiomyopathy: Cardiomyopathies are a heterogeneous group of diseases of the myocardium associated with mechanical and/or electrical dysfunction that usually (but not invariably) exhibit inappropriate ventricular hypertrophy or dilatation and are due to a variety of causes that frequently are genetic. Cardiomyopathies either are confined to the heart or are part of generalized systemic disorders, often leading to cardiovascular death or progressive heart failure-related disability. Because the understanding of etiology or pathogenesis of cardiomyopathy has been limited in veterinary medicine, the previous classification is generally used. It is considered a dilated, hypertrophic and restrictive group on the basis of the predominant morphological and functional abnormalities. In addition, arrhythmogenic right ventricular cardiomyopathy and unclassified cardiomyopathy were also recognized in dogs and/or cats.

• Journal of Acupuncture Research
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• v.33 no.1
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• pp.69-77
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• 2016

Objectives : The objective of this study is to review external approaches using acupuncture and related treatments of hyperpigmentation disorders and their classification in traditional medicine. Methods and Results : Hyperpigmentation was recorded for the first time in Treatise on the Pathogenesis and Manifestations of All Diseases published in 610 A.D. This suggests that the symptom has already been recognized as an independent disease in East Asia for more than 1,400 years. Over the course of several centuries, there has been a significant evolution in the traditional treatments for hyperpigmentation. There are many different types of therapy, including body acupuncture, intradermal acupuncture, ear acupuncture, ear acupressure, blood-letting treatment, pharmacopuncture, plum-blossom needle therapy, burning acupuncture therapy, moxibustion, and guasha. In addition, the traditional classification of hyperpigmentation has been changing shape. However, no attempts have been made to establish the academic linkage between the modern classification of hyperpigmentation disorders and the traditional one, on account of different concepts and names of the ailment. This study was designed in an attempt to identify the linkage of the categorization of the Korean Standard Classification of Disease (KCD) and the traditional classification. Conclusions : Through this literature review, we found that there has been a significant evolution in the treatment of hyperpigmentation disorders in East Asia. Traditional medical treatment for skin disease, including hyperpigmentation, is expected to be further developed with the advancement of science and technology.

• The Journal of the Convergence on Culture Technology
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• v.6 no.4
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• pp.535-543
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• 2020

The KSA caused an error in deriving the statistical measurement items due to the misconfiguration of the safety variables and sub-modules that constitute the safety statistics framework for external causes of death, and pathogenesis, without considering the academic classification system of the field and area of the disaster/accident. By naming it as a mechanism, it was analyzed that the result of poor statistical validity has arrived. Therefore, in this study, by changing the safety parameters according to the WHO safety definition and setting the sub-modules appropriately, the categories of falls, drowning accidents, and accidents exposed to inanimate mechanical forces are classified as accidents at industrial sites and work in daily life. As a result, by systematically re-establishing the complex group of statistical items of the NSO by deriving the field of disasters/accidents according to the nature of the source of external causes of death and setting the relevant domains academically, statistical validity gets better and It is anticipated to play an important role in determining the direction of safe investment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.12 no.1
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• pp.313-337
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• 1999

In oriental medicine, 'chi(痔)' is 'the prolapsed nodule' in 'Ku-gyu(九竅)', but in this paper, I will write about prolapsed nodule only in anus or around it, chi-jil(痔疾), it called hemorrhoid in western medicine. So in the literatual studies on chi(痔) in anus or around it, the results are as follows. 1. The etiology and pathogenesis of ch.i-jil(痔疾) is wind, wetness, dryness, and heat caused by inrregular diet habit, severe drinking and sexual action, deficiency of ki(氣) and hyeol(血). 2. Characteristic symptoms of chi-jil(痔疾) is the prolapsed nodule in the anus or around it, and general symptoms are hematochezia, pain, hernia, swelling, abcess, and mucosal secretion. 3. Chi-jil(痔疾) is classified eight types by characteristic symptom, shape, etiology and pathogenesis. They are mac-chi(脈痔), jang-chi(腸痔), ki-chi(氣痔), hyeol-chi(血痔), joo-chi(酒痔), mo-chi(牡痔), bin-chi(牡痔), and loo-chi(屢痔)(or young-chi(영痔), choong-chi(蟲痔)). Additionally, they are divided into two parts, internal and external chi-jil(痔疾), as likely as classification of internal and external hemorrhoid in western medicine. 4. Treatment of chi-jil(痔疾) is two methods, internal treatment and external treatment. Internal treatment is per os herb-pharmacotheraphy, external treatment is surgical or the other external pharmacotheraphy. There are several external treatment, these are fumigation-theraphy(熏痔法). irrigation-theraphy(洗痔法), paint-theraphy(塗痔法). withering-theraphy(枯痔法), bending-therphy(結紮法) and incisal -theraphy(切開法).

• Applied Biological Chemistry
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• v.41 no.7
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• pp.505-509
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• 1998

Chitinase, which is one of the pathogenesis-related proteins, was examined from Rehmannia glutinosa. Rehmannia chitinases were classified into basic and acidic groups by chitin affinity column chromatography. According to the chitinase pattern by native PAGE, basic chitinases of low Rf values were extracted more under an acidic condition (pH 2.9) than a basic condition (pH 8.8), while acidic chitinases having high Rf values were mainly detected in basic extracts. There were in total seven chitinase isoforms of three basic and four acidic isoforms in Rehmannia. The range of molecular weight of Rehmannia chitinase was from 28 to 32 kD. It showed the possibility of tissue specific expression of acidic chitinases and basic chitinases were mainly detected in root.