• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.3
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• pp.153-158
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• 2017

As social interest in acne treatment has grown, various external preparations have been developed and studied. So, we investigated the external prescription which can treat acne in medical classics, then reviewed and divided it by dynasty. The data for analysis of Herbal formula was taken from 'medicine Dictionary of traditional Chinese medicine prescriptions(中醫方劑大辭典)'. 31 external medicines were searched, 3 were before song(宋) dynasty, 11 were Song(宋) dynasty, 11 were Yuan(元) dynasty, 7 were Ming(明) dynasty and 7 were Qing(淸) dynasty. The recipe and usage were only making them pill(丸) and paste(膏) using grinded medicinal herbs, then rubbing to face. As the age developed, unique manufacturing process(i.e fermentation method), and usage(i.e time-based usage, herbal medicine extracts for wash) were proposed. The external application with oriental medicine for acne used with Angelicae Gahuricae Radix(n=12), Bletillae Rhizoma(n=8), Syzygii Flos, Saposhnikoviae Radix(n=7) and so on. In particular, Bletillae Rhizoma was searched with high frequency in this study, but it was not included or studied in patent composition. The results of this study will provide basic data for future experiments and clinical studies.

• Journal of Korean Medical classics
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• v.20 no.4
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• pp.171-186
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• 2007

The fusion research subjects of Oriental medicine and Bio-Technology are actively advanced. Development of information analysis algorithm for constitution diagnosis using clinical and biological information is started recently. In addition, the research for providing personal oriented treatment information with Diagnosis result is to in the process of advancing. This paper considers the inside and outside of the country technical development trend of research for using clinical and biological information by analyzing patents and papers. It executed information analysis about changes to number of research papers and patents, present state and star higher officer of research facility from the dissertation which it sees. It is known that our country research result is slight so far in quantity and quality as result of analysis. But hereafter it contains a many developmental possibility. Also it reflects the appearance and a growth of new field like bioinformatics from constitution and bio information application field. The combination of bio information similar to constitution and heredity and computing technology to control those information efficiently comes to think with core technique.

• Journal of the Korean Society for information Management
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• v.31 no.2
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• pp.143-171
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• 2014

This study proposes to analyze the concept and introduction of infinite creative space (makerspace) to redefine the roles of existing library spaces. This study also attempts to formulate a suitable program for public library makerspaces by analyzing case studies. Literature review and case study methods are used for deriving the makerspace concept, the evolution of makerspace, the implications posed by makerspace operation domestically and abroad, and the utilization of makerspace. Finally, we suggest story creation programs, topic-based programs reflecting the library characteristics, professional mentoring programs, expert consulting programs, various training programs, patent application support programs, incubator programs, and so on.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.638-645
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• 2014

This paper presents results of a study for development and application of container massive transportation system. The system is aimed to improve competing power of Korean container ports. This paper selects Double stack Multi-Trailer System (DMTS) under consideration of pros-con analysis between three systems alternatives as well as operation process of existing Korean container terminal companies. An analysis of turning radius is undertaken for applying the system. Key elementary technologies was derived by patent analysis. DMTS has no problems in utilization to existing Korean container ports. Further, the system is expected to highly potential to improve operational efficiency in the container ports thanks to its high unit transportation capacity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.1
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• pp.101-113
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• 2015

Application of herbal medicines as natural preservatives has been increased because of its low toxicity or side effect, compared to artificial preservatives. In this study, papers and patents researching anti-microbial activity of herbal medicine were collected and analyzed by the year of publishment, species of bacteria, fungi, or yeasts, and herbal medicines used. After early 2000's, the number of paper publishment has been decreased, while that of patent registration has been increased up to early 2010's. Most studied species were Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa, as gram-positive or gram-negative bacteria, and Candida albicans and Aspergillus niger as fungi. The bark of Cinnamomum cassia (L.) J. Presl was most frequently studies herbal medicine, followed by the roots of Scutellaria baicalensis Georgi and Sophora flavescens Ait. This study demonstrates that herbal medicines can be used as natural preservatives against diverse species of bacteria, fungi, or yeasts with their wide-ranged anti-microbial activities.

• Management & Information Systems Review
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• v.32 no.3
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• pp.263-283
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• 2013

Recently, social enterprises in the korean are gaining more interest but, it seems that many social enterprises are not successful in their sustainability. Therefore government implements various supporting policies for social enterprise. The purpose of this paper is to find new criteria of business development expense through the analysis of submitted application of business development expense. For this study, business development expense data of 126 social enterprises(applied to the Busan in 2013 year) for supporting money are analyzed. The result shows that (1) need to apply 1 or 2 business that is the most important in their business (2) concerns about the patent, engineering development, prototype model development, program development taken IT business are very desirable (3) need to feedback about last year result (4) need to make more elaborate guideline for application (5) none of social enterprise applied co-marketing (brand), therefore a strong inducement plan is need In conclusion, effective and strategic policy of business development expense will be a helpful for the sustainability of social enterprises. In this sense, the results of this study is meaningful to the social enterprise policy, especially business development expense, maker.

• Journal of Intelligence and Information Systems
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• v.20 no.1
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• pp.15-34
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• 2014

Overall, accuracy as a performance measure does not fully consider modular accuracy: the accuracy of classifying 1 (or true) as 1 is not same as classifying 0 (or false) as 0. A smarter classification algorithm would optimize the classification rules to match the modular accuracies' goals according to the nature of problem. Correspondingly, smarter algorithms must be both more generalized with respect to the nature of problems, and free from decretization, which may cause distortion of the real performance. Hence, in this paper, we propose a novel vertical boosting algorithm that improves modular accuracies. Rather than decretizing items, we use simple classifiers such as a regression model that accepts continuous data types. To improve the generalization, and to select a classification model that is well-suited to the nature of the problem domain, we developed a model selection algorithm with smartness. To show the soundness of the proposed method, we performed an experiment with a real-world application: predicting the intellectual properties of e-transaction technology, which had a 47,000+ record data set.

• Food Science and Industry
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• v.50 no.1
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• pp.67-73
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• 2017

Control of food pathogens is critical in food safety field. Norovirus is one of the major causes of gastroenteritis and food poisoning worldwide, however, currently, there is not a vaccine or a specific drug available for its treatment. There are several methods to inactivate norovirus during food processing by chemical and physical treatments, however, the use of natural substance has been suggested as an optional strategy due to their safety and consumer preference. In this study supported by Ministry of Food and Drug Safety in Korea, we identified novel plant-derived substances with significant anti-norovirus activities. The aim of this project was to determine the antiviral activity of a wide range of natural substances, including plant-derived extracts and essential oils, using a norovirus surrogate system, human norovirus replicon-bearing cells, and mouse in vivo experiments. During the activity screening test, we identified novel anti-norovirus substances or oils using plaque assay with MNV-1. Six selected substances were formulated into an optimum mixture and used as an ingredient for salad sauce of which anti-novovirus activity was confirmed(pending for patent and paper submission). The potential application of selected natural substances as a metal surface sanitizer was also tested. Interestingly, the mixture of selected natural compounds showed a significant inhibitory effect against norovirus. These results suggest that these substances may be used as food ingredient with anti-norovirus antivity or components for surface sanitizers to prevent norovirus contamination.

• Journal of Environmental Impact Assessment
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• v.31 no.6
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• pp.465-474
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• 2022

In order to achieve carbon neutrality, it is necessary to commercialize and popularize carbon dioxide capture technology, so the purpose of this study is to put forward the design of public facilities suitable for public environment. In the design direction of public facilities for carbon capture and environmental purification, the application of carbon capture technology in air, the application of carbon capture and adsorption materials, and carbon reduction recycling are selected for development. In order to achieve carbon neutrality, this study develops a new concept of public facility design which is different from the existing public facilities in public space. From this point of view, it has great enlightenment significance. Public facilities adopting carbon-neutral technology are environmentally friendly public facilities that conform to the times, and can be installed in parks, roads and other spaces. With the rest of citizens and the role of communities, it is expected to contribute to popularization and activation.

• Journal of Veterinary Clinics
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• v.40 no.1
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• pp.8-15
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• 2023

Atopic dermatitis (AD) is a common skin disease in animals and several therapeutic trials with various drugs have been conducted for more effective management of AD. However, these trials have not been able to properly address all the aspects of AD management because of the lack of good efficacy or due to significant side effects of the drugs being tested. Synbio-glucan functional spray is a functional skin spray using Synbio-glucan composed of β-glucan and probiotics. We designed a functional spray composed of Synbio-glucan (patent application number:10-1805863), distilled water, glycerin, solubilizer, and 40% alcohol. We tested the efficacy and safety of the functional spray on six dogs with AD. The trial was conducted with the consent of the caregivers. The spray was applied to the skin lesions, including the trunk, axillae, inguinal region, or periocular areas, thrice a day for 30 days. To evaluate the efficacy of this functional spray, we assessed the pruritus visual analog scale (PVAS) and the canine atopic dermatitis extent and severity index (CADESI)-4. At the end of one month, the results clinical scores after functional spray treatment showed a significant decrease in the PVAS (p = 0.03) and CADESI-4 (p = 0.03) in all the subject dogs with AD. This study thus confirmed that the Synbio-glucan functional spray is efficacious and safe for the treatment of AD in dogs.