• YAKHAK HOEJI
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• v.44 no.2
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• pp.189-192
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• 2000

We examined a dermal pharmacokinetics for a new SYC-fentanyl patch in rabbits. Determination of fentanyl in the plasma was performed using a gas chromatography with nitrogen-phosphorus detection system and a capillary column. One patch per animal (fentanyl 2.5 mg) was applied to clipped back skin for 72 hours. The plasma fentanyl concentration profile of SYC-patch was similar to that of a conventional patch (Durogesi $c^{R}$, Janssen Co.). No significant difference was observed in the pharmacokinetic parameters, the area under the concentration-time curve (AU $C^{0-}$72hrs/) and the total area under the first moment-time curve (AUM $C^{0-}$7hrs/), between the two patch types. The AU $C^{0-}$7hrs/ and AUM $C^{0-}$72hrs/ of durogesi $c^{R}$ were 183.3$\pm$46.28 ng＊hr/ml and 6,450$\pm$1,939ng＊h$r^2$/ml, and those of SYC-fentany patch were 217.2$\pm$50.51$\pm$ng＊hr/ml and 8,022$\pm$2,245ng＊h$r^2$/ml, respectively (n=3). This result indicates that the new SYC patch has a similar bioavailability compared to durogesi $c^{R}$ patch. Therefore, the SYC-patch may be considered as a bioequivalent fentanyl patch.patch.tch.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.8 no.5
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• pp.56-67
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• 2005

Rapid and reckless economical development is causing nationwide deforestation; more and more forest is being developed to be used as a base for economic advancement. While benefiting the national economy, this destruction of forest is creating a serious problem in the National Land Plan. To solve this problem, it is imperative to understand the current condition of damaged forest and make an environment-friendly plan. This paper explains the principles of spatial plan and sets the criteria for the plan, such as patch size, connectivity, and edge of the Landscape Ecology. The paper assesses the conservational value of area that are currently being developed or planned to be developed to figure out the current environmental situation. This conservational value was verified by the field survey. The result of assessment appears that the patch size of the major mountains in site is over 1,000ha and edge is located widely beside roads. The area of the high connectivity is located agriculture area in valley or narrow roads. The research shows that the patch size is related to biodiversity the larger the patch size, the more populated the species are. The research also reveals the conservational value indicated by degree of connection to forest, difference in the structure of vegetation between core area and edge area, and effects of surrounding environment. In further study, we will assess other criteria of conservation value, such as patch shape and fragmentation to the Landscape Ecology, and apply those criteria in biological aspects of the spatial plan.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.12
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• pp.1233-1238
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• 2003

In this paper, radially corrugated circular-type microstrip patch antenna was devised and manufactured for GPS (center frequency: 1.575 GHz). Radially corrugated circular-type microstrip patch antenna having radiational corrugation-patch contributed to add size reduction ratio by lowering the resonant frequency because the edge current also has the extended and perpendicular path. As a result, radially corrugated circular-type microstrip patch antenna has 28 % area reduction than planer circular-type patch antenna for linear polarization and 27.7 % area reduction than planer circular-type patch antenna for circular polarization. Radially corrugated circular-type microstrip patch antenna is suitable for miniaturized receive antenna for GPS which has the characteristic of gain 2.1 dBd, axiai ratio 1.3 dB, 2 dB axial bandwidth 15 MHz(0.9 %).

• Journal of the Korean Society of Environmental Restoration Technology
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• v.16 no.4
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• pp.53-63
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• 2013

The purpose of this study is to analyze impacts of the forest fragmentation caused by development project. Furthermore, to investigate the applicability of landscape indicator when 'Feasibility of forest land conversion to other use' is conducted. The study site was consisted of golf course development and road construction. It is to compare before and after impacts of areal and linear development. As for the methods, selecting landscape indices, clustered into 3 Categories have been utilized. Category I was concerned with 'size of forest patches', II as 'shape of forest patches', and III as 'Core Area' These were calculated by FRAGSTATS, the program for analyzing fragmentation. The results showed that linear development caused more fragmented than areal development projects. Also, patch size, patch shape and core area are related to impacts of development, while Patch size decreased, patch shape and core area increased after development. Therefore, it is necessary to minimize the impacts of forest by considering fragmentation when development project is planned.

• Animal cells and systems
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• v.15 no.1
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• pp.73-78
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• 2011

Estimating the habitat potential of inland forest patches for birds requires the modeling of species-area relationships, or relationships between habitat size and numbers of bird species in each patch. The accurate estimation of speciesarea relationships significantly reduces the effort required to recognize the number of species living in each patch. The objective of this study was to estimate the relationship between forest patch size and bird species diversity in Dangjin County, in northwest South Korea, based on the sizes of inland forest patches. KOMPSAT-2 images were obtained and ortho-rectified to construct a map of the target forest patches. The numbers of birds per patch were surveyed four times: August 2008, September 2008, February 2009 and May 2009. Regression models were derived to explain the relationships between the numbers of bird species and patch size. A model that was derived using data from all four observation periods had the highest coefficient of determination ($R^2$). According to these models, the numbers of bird species at first increased linearly with increasing patch size; however, the curve then plateaued. Our model including observations from four seasons will be useful for estimating the numbers of bird species in other inland forest patches in South Korea.

• Journal of Chest Surgery
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• v.2 no.2
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• pp.167-167
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• 1969

Two groups of esophagus graft were done in canine esophagus in 34 adult mongrel dogs. For the first group segmental replacement graft was done with fresh autologous pericardium tube, and for the second, patch graft was done utilizing fresh autologous pericardium, fresh homologous pericardium,and dacron piece. All eight dogs in the first segmental replacement graft group died 2 to 5 days after operation with severe empyema caused by anastomosis disruption. Among 26 patch graft dogs 2 died during operation and 7 died 13 to 18 days after operation. For the 17 long-term patch grafted survivors esophagography and postoperative weight check were done. Postoperative stool was collected and examined for dacron patch excretion. One, two, three, and four months postoperative long-term survivors were sacrificed to obtain specimens in each group respectively and the following observations were made.I. Survival; Autologous pericardium patch group showed no mortality but in homologous pericardium and dacron patch group only two thirds were long-term survivors. II. Postoperative swallowing; There was no case which demonstrated postoperative dysphagia. About half of the cases showed postoperative weight increase and in only 3 cases weight decrease followed operation. III. Dacron patch was excreted in the stool 8 to 23 days after operation. Animals which excreted dacron patch up to 9 days after operation all died of empyema due to anastomosis disruption.IV. Postoperative esophagogram; All esophagograms in each group showed no leakage of barium, no passage disturbances and no remarkable stenotic signs.V. Morphological findings; [A] Macroscopical findings; In one month group specimens of each group dense adhesion with surrounding structures was noted and luminal surface was smooth with contraction of the patched area. In two month groups anastomosis sutures were still exposed but patched area showed lesser abnormality. In three to four months groups sutures were covered completely and patched area showed only very slight signs of contraction. [B] Microscopic findings; In one month group luminal surface of the replaced tissue [transplanted tissue] showed almost complete epithelial covering that is composed of several layers of squamous cells with no evidence of keratinization. Basement membrane was also well distinct throughout. Slight to minimal inflammatory cells comprising of large mononuclears, lymphocytes and plasma cells were observed in the subepithelial fibrous stroma consisted entirely of loose fibrous tissue containing many newly formed capillaries and fibroblastic proliferation. Scattered suture granulomas were found, few of which became acutely inflamed. In two months group repairing process progressed with lesser degree of inflammatory cell infiltration and young capillary proliferation. Fibrous tissue was more matured showing even focal collagenization.Suture granuloma persisted but with lesser reactive changes. Epithelial covering was that of a mature non-keratinizing stratified squamous epithelium. In three and four months groups the replaced area showed essentially similar histological findings. However, subepithelial stroma still consisted entirely of connective tissue without evidence of smooth muscle regeneration. In this group, inflammatory cell infiltration was minimal or negligible. Among these patch materials autologous pericardium group showed the most satisfactory repairing process.The above mentioned results may signify the feasibility of autogenous pericardium patch graft in clinical esophageal surgery.

• Journal of Chest Surgery
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• v.2 no.2
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• pp.168-186
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• 1969

Two groups of esophagus graft were done in canine esophagus in 34 adult mongrel dogs. For the first group segmental replacement graft was done with fresh autologous pericardium tube, and for the second, patch graft was done utilizing fresh autologous pericardium, fresh homologous pericardium,and dacron piece. All eight dogs in the first segmental replacement graft group died 2 to 5 days after operation with severe empyema caused by anastomosis disruption. Among 26 patch graft dogs 2 died during operation and 7 died 13 to 18 days after operation. For the 17 long-term patch grafted survivors esophagography and postoperative weight check were done. Postoperative stool was collected and examined for dacron patch excretion. One, two, three, and four months postoperative long-term survivors were sacrificed to obtain specimens in each group respectively and the following observations were made. I. Survival; Autologous pericardium patch group showed no mortality but in homologous pericardium and dacron patch group only two thirds were long-term survivors. II. Postoperative swallowing; There was no case which demonstrated postoperative dysphagia. About half of the cases showed postoperative weight increase and in only 3 cases weight decrease followed operation. III. Dacron patch was excreted in the stool 8 to 23 days after operation. Animals which excreted dacron patch up to 9 days after operation all died of empyema due to anastomosis disruption. IV. Postoperative esophagogram; All esophagograms in each group showed no leakage of barium, no passage disturbances and no remarkable stenotic signs. V. Morphological findings; [A] Macroscopical findings; In one month group specimens of each group dense adhesion with surrounding structures was noted and luminal surface was smooth with contraction of the patched area. In two month groups anastomosis sutures were still exposed but patched area showed lesser abnormality. In three to four months groups sutures were covered completely and patched area showed only very slight signs of contraction. [B] Microscopic findings; In one month group luminal surface of the replaced tissue [transplanted tissue] showed almost complete epithelial covering that is composed of several layers of squamous cells with no evidence of keratinization. Basement membrane was also well distinct throughout. Slight to minimal inflammatory cells comprising of large mononuclears, lymphocytes and plasma cells were observed in the subepithelial fibrous stroma consisted entirely of loose fibrous tissue containing many newly formed capillaries and fibroblastic proliferation. Scattered suture granulomas were found, few of which became acutely inflamed. In two months group repairing process progressed with lesser degree of inflammatory cell infiltration and young capillary proliferation. Fibrous tissue was more matured showing even focal collagenization. Suture granuloma persisted but with lesser reactive changes. Epithelial covering was that of a mature non-keratinizing stratified squamous epithelium. In three and four months groups the replaced area showed essentially similar histological findings. However, subepithelial stroma still consisted entirely of connective tissue without evidence of smooth muscle regeneration. In this group, inflammatory cell infiltration was minimal or negligible. Among these patch materials autologous pericardium group showed the most satisfactory repairing process. The above mentioned results may signify the feasibility of autogenous pericardium patch graft in clinical esophageal surgery.

• The Korean Journal of Ecology
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• v.17 no.2
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• pp.120-130
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• 1994

Stages of vegetation development on talus area were studied to examine temporal changes in species composition and vegetation structure, and to elucidate the mechanism of early patch formation. While ground coverage of lichens, which may form substrate for moss colonization and mitigate the heat-stress on rocks, decreased gradully, coverage of mosses increased slightly during primary succession. Ecological role of mossess related with water retention in community may be very important not only at pioneer stage but also at later stages because of little soil development on this talus area. Species diversity and species richness increased during the early stages of succession. Parthenocis년 tricuspidata and Sorbaria sorbifolia var. stellipa dominated in liana stage, Ulmus davidiana for. suberosa and Lindera obtusiloba in shrub stage, and Fraxinus rhynchophylla and Actinidia arguta in subtree stage, however, was composed of mixed forest of several tree species. U. davidiana for. suberosa, L. obtusiloba, Securinega suffruticosa and Rhus chinensis were relatively important woody species in early patch forming process. The results, however, suggested that early establishment on talus area might be strongly associated with chance for safe-site because both pioneer species and later species could take part in early patch forming process.

• The Journal of the Korea Contents Association
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• v.14 no.2
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• pp.1-9
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• 2014

Image inpainting is the widely used technique to restore a damaged region or to fill a hole in an image. The exemplar-based technique effectively generates new texture by copying colour values of the most correlated patch in the source into the empty region of the current patch. In traditional exemplar-based synthesis, the patch correlation is computed using only the already filled pixels of the current patch. Thus, by ignoring the correlation between the hole regions of the two patches, an undesirable patch which is highly correlated with the current patch in the already filled area but considerably dissimilar in the area to be filled can be selected, which results in bad texture propagation. To avoid such problems, a new exemplar-based inpainting method using patch extrapolation is proposed. The empty part of the current patch is extrapolated beforehand, and then the complete patch is used for finding its exemplar. Experimental results show that the proposed method provides more natural synthesis results than the conventional ones.

• Journal of Environmental Impact Assessment
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• v.22 no.3
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• pp.219-230
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• 2013

Species distribution modeling is one of the most effective habitat analysis methods for wildlife conservation. This study was for evaluating the suitability of species distribution to distance between forest patches in Seoul city using tits. We analyzed the distribution of the four species of tits: varied tit (Parus varius), marsh tit (P. palustris), great tit (P. major) and coal tit (P. ater), using the landscape indexes and connectivity indexes, and compared the resulting suitability indexes from 100m to 1,000m. As factors affecting to the distribution of tits, we calculated landscape indices by separating them into intra-patch indices (i.e. logged patch area (PA), area-weighted mean patch shape index (PSI), tree rate (TR)) and inter-patch indices (i.e. patch degree (PD), patch betweenness (PB), difference probability of connectivity (DPC)), to analyze the internal properties of the patches and their connectivity by tits occurrence data using logistic regression modeling. The models were evaluated by AICc (Akaike Information Criteria with a correction for finite sample sizes) and AUC (Area Under Curve of ROC). The results of AICc and AUC showed DPC, PA, PSI, and TR were important factors of the habitat models for great tit and marsh tit at the level of distance 500~800m. In contrast, habitat models for coal tit and varied tit, which are known as forest interior species, reflected PA, PSI, and TR as intra-patch indices rather than connectivity. These mean that coal tit and varied tit are more likely to find a large circular forest patch than a small and long-shaped forest patch, which are higher rate of forest. Therefore, different strategies are required in order to enhance the habitats of the forest birds, tits, in a region that has fragmented forest patches such as Seoul city. It is important to manage forest interior areas for coal tit and varied tit, which are known as forest interior species and to manage not only forest interior areas but also connectivity of the forest patches in the threshold distance for great tit and marsh tit as adapted species to the urban ecosystem for sustainable ecosystem management.