• 한국균학회지
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• 제46권3호
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• pp.235-239
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• 2018

Basil (Ocimum spp.) is a popular herb grown worldwide. During the past fifteen years, a downy mildew pathogen has caused considerable damage to basil cultivations. In August 2017, downy mildew disease symptoms were found on Basil Tree (or long foot Basil Tree), which was developed by the grafting of two basil varieties and is a continuous harvest plant with a woody trunk. The present study reports the occurrence of downy mildew disease in basil Tree and identifies the causal pathogen, as Peronospora belbahrii.

• Tuberculosis and Respiratory Diseases
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• 제70권5호
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• pp.371-383
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• 2011

The number of immunocompromised patients has increased over the past decades due to HIV infection, solid and stem cell transplantation, intensified chemotherapy and treatment of autoimmune disease. Pneumonia is a major cause of both morbidity and mortality in immunocompromised patients. Clinical management of pneumonia is difficult, since differential diagnosis in this setting is broad and includes both infectious and noninfectious processes. Because the development of pneumonia in immunocompromised patients is frequently life threatening, early therapeutic and diagnostic intervention is essential to obtain better outcomes.

• 대한의생명과학회지
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• 제21권3호
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• pp.131-134
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• 2015

High sodium diet has been touted to be a major risk factor of disease in developed countries. The disease most closely associated with a high sodium diet is cardiovascular diseases. Autoimmune diseases are another broad spectrum of diseases that is associated with developed countries. In the past few years, several key scientific findings have revealed that a high sodium diet could also impact the pathogenicity of autoimmune diseases. In this review, we will highlight key results from such investigations and put it in context of high sodium diet and autoimmunity.

• Journal of Dental Anesthesia and Pain Medicine
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• 제16권2호
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• pp.147-150
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• 2016

The prevalence of thyroid disease, particularly hyperthyroidism, has rapidly increased in Korea in the past 10 years. Therefore, it is important to consider the complete medical history including thyroid disease in patients under dental treatment. Both the drugs used for dental treatment and psychological symptoms associated with treatment can induce emergencies in hyperthyroid patients. This case report considers emergency situations during dental treatment for hyperthyroid patients, and discusses risk factors and related concerns.

• Archives of Pharmacal Research
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• 제26권6호
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• pp.433-440
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• 2003

Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology limited to the large intestine. The disease is prevalent in industrial societies and is associated with specific ethnic populations. A number of murine models, each focused on distinct aspects of the disease process, were developed over the past 20 years to further our understanding of the pathogenesis of UC. These models have been and remain our best resource for the study of the disorder as a result of their homology to human UC and the ease in which they can be manipulated and examined. This review examines and distills what has been learned from these models and how this information is related back to human UC.

• Biomolecules & Therapeutics
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• 제19권4호
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• pp.398-410
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• 2011

Over the past few decades, our understanding of the epidemiology and immunopathogenesis of Hodgkin lymphoma (HL) has made enormous advances. Consequently, the treatment of HL has changed significantly, rendering this disease of the most curable human cancers. To date, about 80% of patients achieve long-term disease-free survival. However, therapeutic challenges still remain, particularly regarding the salvage strategies for relapsed and refractory disease, which need further identification of better prognostic markers and novel therapeutic schemes. Although the precise molecular mechanism by which Epstein-Barr virus (EBV) contributes to the generation of malignant cells present in HL still remains unknown, current increasing data on the role of EBV in the pathobiology of HL have encouraged people to start developing novel and specific therapeutic strategies for EBV-associated HL. This review will provide an overview of therapeutic approaches for acute EBV infection and the classical form of HL (cHL), especially focusing on EBV-associated HL cases.

• 한국전자통신학회논문지
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• 제7권4호
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• pp.917-924
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• 2012

본 연구는 우리나라 19세 이상 성인의 흡연 상태와 치주질환 위험도와의 관련성을 분석하여 흡연이 치주질환에 미치는 영향을 파악하고자 시도되었다. 연구결과에서 전체 대상자의 CPI 평균은 1.92이었고, 전체 대상자 6989명 중 CPI가 0-2인 그룹은 4707명(67.3%), 3-4인 그룹은 2282명(32.7%)이었다. 혼란변수를 보정하지 않았을 때 CPI가 3 이상인 그룹에서는 전혀 흡연을 하지 않는 그룹에 비해 과거 흡연을 한 그룹에서의 치주질환의 유병율에 대한 위험도는 1.78배(95% CI:1.56-2.02), 현재 흡연을 하고 있는 그룹에서는 1.75배(95% CI:1.55-1.82)로 증가하였다. 성별, 연령, 교육수준과 당뇨병 유무를 보정하고도 치주질환의 유병율에 대한 위험도는 전혀 피우지 않는 그룹보다 과거 흡연한 그룹에서 1.28배 (95% CI:1.08-1.53), 현재 흡연하는 그룹에서는 1.82배(95% CI:1.54-2.16)로 높았다. 이에 흡연과 치주질환이 연관성이 있는 것으로 나타나 적극적인 홍보를 통한 환자 스스로의 확고한 인식확립과 더불어 치과위생사는 진료실 내 체계적인 금연교육지도를 함으로써 치주 건강향상에 주력할 필요가 있다고 사료된다.

• 한국융합학회논문지
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• 제10권12호
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• pp.135-142
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• 2019

본 연구에서는 동거형태에 따른 노인의 심혈관질환과 치주질환의 분포정도 및 관계를 분석하여 각각 특성에 맞는 프로그램 개발을 위한 기초 자료를 제공하기 위해 국민건강영양조사 제6기의 자료를 분석하였다. 일반적 특성에 따른 심혈관질환자의 분포는 가족동거노인의 경우 성별, 교육수준, 독거노인의 경우에는 나이, 소득수준에 따라 차이가 있었다. 구강건강상태 및 구강보건형태와 심혈관질환자의 분포는 가족동거노인의 경우 최근 1년간 치통경험이 있는 군, 최근 1년간 구강검진을 하지 않은 군, 치주염군, 독거노인은 구강건강상태가 나쁘다고 인지한 군과 치주질환 정상 군에서 더 많았다. 심혈관질환과 치주질환의 관계에서는 가족동거노인은 고혈압이 관련이 있었고 독거노인의 경우에는 관련이 없었다. 심혈관질환과 치주질환은 노인에게 가장 많은 질환이며 두 질환의 발생 연관성이 전혀 없다고는 할 수 없기 때문에 두 질환을 같이 고려하여 추후 건강상태 확인 및 다양한 가족동거 형태에 따른 차이점에 대해서 반복연구를 통해 구체적인 건강관리 방법이 논의되어야 한다.

• 대한영상의학회지
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• 제79권5호
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• pp.276-281
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• 2018

면역글로불린 G4 (Immunoglobulin G4; 이하 IgG4) 관련 폐 질환은 지난 몇 년간 활발하게 기술되어 온 질환이다. IgG4 관련 폐 질환의 영상의학적 소견은 환자마다 다양하게 알려져 있으나, 질병의 진행에 따른 다양한 영상 소견들을 장기 추적한 연구는 보고되지 않았다. 본 증례 보고에서는 비교적 장기간의 추적을 시행한 2예를 통해, IgG4 관련 폐 질환의 다양한 초기 및 후기 컴퓨터단층촬영 소견들을 고찰하였다. 비교적 초기 CT에서 보였던 결절성 혹은 미만성 간유리음영과 달리, 벌집모양음영이나 견인성 기관지확장증은 후기 소견들로 생각되었다. 고형 결절들은 초기 및 후기에서 모두 보였으나, 새로운 결절의 발생 혹은 기존 결절들의 크기 증가가 질병이 진행함에 따라 나타났다. 소엽간 중격 비후와 종격동 및 폐문 림프절 비대는 질병의 후기에서도 지속적으로 관찰되었다. 이는 IgG4 관련 폐 질환의 정확하고 시기적절한 진단에 도움이 될 것으로 기대된다.

• 한국학교보건학회지
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• 제26권3호
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• pp.144-157
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• 2013

Purpose: Health management programs should provide comprehensive health services for students and staffs at schools. Health management programs are critical for helping students become adults with physically, mentally, and socially good health conditions. The aim of this study was to identify the past and present history of health management programs and health laws to help schools develop future health plans. Methods: This study was conducted by analyzing reference data collected using data from Ministry of Education and Science Technology, Korean Educational Development Institute, Korea Centers for Disease Control and Prevention, and National Statistical Office as well as legal documents from the Legislative Office related to school health from 2001 to 2010. Results: Health management programs in schools included three sections: disease prevention and control, physical examinations, and prevention of communicable diseases. Disease prevention and controls consisted of obesity control, drug abuse prevention and control,and management of students' mental health. Various strategies and services were developed to improve health status of students for 10 years from 2001 to 2010. School health laws and systems have been established for disease prevention, physical examinations and communicable disease control as well, to improve students' health as well. Conclusion: The history of health management programs has a number of implications to help design future plans for school health programs and services for students and staffs.