• Biotechnology and Bioprocess Engineering:BBE
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• 제6권1호
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• pp.42-50
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• 2001

The activity of immobilized cell-support particle aggregates is influenced by physical and biochemical elements, mass transfer, and physiology. Accordingly, the mathematical model discussed in this study is capable of predicting the steady state and transient concentration profiles of the cell mass and substrate, plus the effects of the substrate and product inhibition in an immobilized cell-support aggregate. The overall mathematical model is comprised of material balance equations for the cell mass, major carbon source, dissolved oxygen, and non-biomass products in a bulk suspension along with a single particle model. A smaller bead size and higher substrate concentration at the surface of the particle, resulted in a higher supply of the substrate into the aggregate and consequently a higher biocatalyst activity.

• 한국대기환경학회지
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• 제12권3호
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• pp.243-254
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• 1996

The main purpose of this study is to investigate the collection efficiency characteristics of a cylindrical ESP. To do that, it is necessary to analyze the electric field, gas flow field, and mechanism of particle movement by numerical simulation based on EHD model. For a gas flow field, Navier-Stokes equation involving the electric source term was solved by SIMPLE algorithm. In case of the electric field, the current continuity and electric field equations were solved by S.O.R. method. The analysis of particle movement was performed on the basis of PSI-CELL model from the Lagrangian viewpoint. The results showed that the influence on the gas flow field by the electric field is almost negligible in a cylindrical ESP. The particle drift velocity $V_P$ toward the collection surface is increased continuously by the electrostatic force due to the rise of particle charge as the particle is moving to the flow direction and the particle size becomes larger. The collection efficiency is to quitely higher with the increase of applied voltage for the same particle size, while becomes smaller as the inlet velocity is increased.

• 대한기계학회논문집B
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• 제23권6호
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• pp.778-787
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• 1999

In this study, the autoignition process of liquid fuel, injected into hot and stagnant air in a 2-D axisymmetric confined cylindrical combustor, has been investigated. Eulerian-Lagrangian scheme was adopted to analyze the two-phase flow and combustion. The unsteady conservation equations were used to solve the transition of the gas field. Interactions between two phases were accounted by using the particle source in cell (PSI-Cell) model, which was used for detailed consideration of the finite rates of transports between phases. And infinite conduction model was adopted for the vaporization of droplets. The results have shown that the process of the autoignition consists of heating up of droplets, vaporization, mixing and ignition. The ignition criteria could be determined by the temporal variations of temperature, reaction rate and species mass fraction. And the effects of various parameters on ignition phenomena are examined. These have shown that the increasing the reaction rate and/or the vaporization rate can reduce the ignition delay time.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2002년도 추계 학술대회논문집
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• pp.41-46
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• 2002

A numerical simulation was made to determine the motion of particles in the fluid. The simulation is based on the Eulerian-Lagrangian method. The fluid motion was solved using a PISO-based finite-element method and a $\kappa-\epsilon$ model of turbulence. In the Lagrangian method for the solid phase, the trajectories of particles are calculated by integrating the equations of motion of a single Particle, and the collision between particles are taken into account. The influence of particles on the fluid phase is taken into account by introducing source terms in the Eulerian equations govering the fluid flow. It is known as the particle-source-in-cell (PSIC) method. Also, the turbulent effect in the particles and fluid notion is considered. The numerical results were compared with the experiment for a two-phase flow in a vertical pipe.

• Environmental Analysis Health and Toxicology
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• 제19권4호
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• pp.335-344
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• 2004

Diesel exhaust particle (<2.5 ${\mu}{\textrm}{m}$, DEP$_{2.5}$) is known to be probarbly carcinogenic (IARC group 2A). DEP$_{2.5}$ contains organic compounds such as polycyclicaromatic hydrocarbon (PAH), heterocyclic compounds, phenols, and nitroarenes. Reactive oxygen species (ROS) are generated by DEP$_{2.5}$ without any biological activation system. Therefore, an alternative mechanism by which DEP$_{2.5}$ could be carcinogenic is known by the generation of oxidative DNA damage. The aim of this study was to investigate genotoxic effects of DEP$_{2.5}$ using single cell gel electrophoresis. In order to evaluate the mechanisms of DEP$_{2.5}$ genotoxicity, the rat micro-some mediated and DNA repair enzyme treated comet assays together with routine comet assay were performed. DEP$_{2.5}$ was collected from diesel engine bus and dichloromethane extract was obtained. The organic extract of DEP$_{2.5}$ revealed DNA damage itself in NIH/3T3 cells. And it showed both oxidative and microsome mediated DNA damages. Vitamin C as an model antioxidant reduced DNA damage in endonuclase III treated comet assay. One of flavonoid, galangin as a CYP1A1 inhibitor reduced DNA damage in the presence of S-9 mixture. Our results show that DEP$_{2.5}$ are genotoxic and a great source of oxidative stress, but antioxidants can significantly reduce oxidative DNA damages. And DEP$_{2.5}$ may contain indirect mutagens which can be inhibited by CYP inhibitors.d by CYP inhibitors.

• 대한기계학회논문집
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• 제15권6호
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• pp.2073-2082
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• 1991

본 연구에서는 선회유동과 재순환영역이 있는 제한된 동축 분류유동(confined coaxial jet flow)을 갖는 연소기에 대하여 노즐을 통하여 분사된 연료액적의 증발 및 연소, 그리고 주위기체유동에 관한 제반현상을 정상상태 하에서 모사하고자 하는데 그 목적이 있으며 수치계산에 의한 이론적 해석방법으로 기상은 오일러 방식, 액상은 라 그란지 방식을 채택하였고 후술될 증발 및 연소모델을 적용하였다.

• 대한기계학회논문집
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• 제14권3호
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• pp.702-715
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• 1990

본 연구에서는 개수로 후래시 증발기 내부를 단순화된 형태로 가정하여 앞서 언급된 운전조건 및 유입되는 기포의 갯수유량(혹은 기공률)에 따라 증발기 내부의 속 도 및 온도분포를 수치적으로 계산해 보고자 한다. 이를 위해 유동을 정상상태의 난 류유동으로 가정하였으며, 구형의 기포에 대해 평균적인 운동 및 성장을 지배하는 방 정식을 세우고 상변화에 의한 증발량을 구하였다. 즉 입구에서 유입된 기포들이 성 장하면서 자유표면을 통해서 빠져나가는 운동 궤적을 추적함으로써 증발기 내부 유동 의 속도 및 온도분포를 구하고 이를 바탕으로 총 증발량 및 증발성능을 예측해 보고자 하는 것이다. 그리고 이렇게 계산된 결과들을 기존의 실험값과 비교하였다.