• Title/Summary/Keyword: Particle Acceleration

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Development of shock wave induced microparticle acceleration system based on laser ablation and its application on drug delivery (충격파를 이용한 레이저 어블레이션 기반의 마이크로 입자 가속 시스템 개발 및 약물전달 응용)

  • Choi, Ji-Hee;Gojani, Ardian B.;Lee, Hyun-Hee;Yoh, Jai-Ick
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.36 no.6
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    • pp.587-593
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    • 2008
  • Transdermal and topical drug delivery with minimal tissue damage has been an area of vigorous research for years. Our research team has initiated the development of an effective method for delivering drug particles across the skin (transdermal) for systemic circulation, and to localized (topical) areas. The device consists of a laser ablation based micro-particle acceleration system that can be integrated with endoscopic surgical techniques. We have successfully delivered 3μm size cobalt particles into gelatin models that represent soft tissue with remarkable penetration depth.

Position Based Triangulation for High Performance Particle Based Fluid Simulation (위치 기반 삼각화를 이용한 입자 기반 유체 시뮬레이션 가속화 기법)

  • Hong, Manki;Im, Jaeho;Kim, Chang-Hun;Byun, Hae Won
    • Journal of the Korea Computer Graphics Society
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    • v.23 no.1
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    • pp.25-32
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    • 2017
  • This paper proposes a novel acceleration method for particle based large scale fluid simulation. Traditional particle-based fluid simulation has been implemented by interacting with physical quantities of neighbor particles through the Smoothed Particle Hydrodynamics(SPH) technique[1]. SPH method has the characteristic that there is no visible change compared to the computation amount in a part where the particle movement is small, such as a calm surface or inter-fluid. This becomes more prominent as the number of particles increases. Previous work has attempted to reduce the amount of spare computation by adaptively dividing each part of the fluid. In this paper, we propose a technique to calculate the motion of the entire particles by using the physical quantities of the near sampled particles by sampling the particles inside the fluid at regular intervals and using them as reference points of the fluid motion. We propose a technique to adaptively generate a triangle map based on the position of the sampled particles in order to efficiently search for nearby particles, and we have been able to interpolate the physical quantities of particles using the barycentric coordinate system. The proposed acceleration technique does not perform any additional correction for two classes of fluid particles. Our technique shows a large improvement in speed as the number of particles increases. The proposed technique also does not interfere with the fine movement of the fluid surface particles.

Research on Acceleration Mechanism of Inflight Particle and Gas Flow Effect for the Velocity Control in Vacuum Kinetic Spray Process (진공상온분사(VKS) 공정에서의 비행입자 가속 기구 및 속도제어를 위한 가스 유량 효과에 관한 연구)

  • Park, Hyungkwon;Kwon, Juhyuk;Lee, Illjoo;Lee, Changhee
    • Korean Journal of Materials Research
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    • v.24 no.2
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    • pp.98-104
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    • 2014
  • Vacuum kinetic spray(VKS) is a relatively advanced process for fabricating thin/thick and dense ceramic coatings via submicron-sized particle impact at room temperature. However, unfortunately, the particle velocity, which is an important value for investigating the deposition mechanism, has not been clarified yet. Thus, in this research, VKS average particle velocities were derived by numerical analysis method(CFD: computational fluid dynamics) connected with an experimental approach(SCM: slit cell method). When the process gas or powder particles are accelerated by a compressive force generated by gas pressure in kinetic spraying, a tensile force generated by the vacuum in the VKS system accelerates the process gas. As a result, the gas is able to reach supersonic speed even though only 0.6MPa gas pressure is used in VKS. In addition, small size powders can be accelerated up to supersonic velocity by means of the drag-force of the low pressure process gas flow. Furthermore, in this process, the increase of gas flow makes the drag-force stronger and gas distribution more homogenized in the pipe, by which the total particle average velocity becomes higher and the difference between max. and min. particle velocity decreases. Consequently, the control of particle size and gas flow rate are important factors in making the velocity of particles high enough for successful deposition in the VKS system.

A Study of Collision Characteristics in differential sedimentation according to variation of Ionic Strength, Zeta Potential and Particle Size (이온화세기, 제타전위, 입자크기에 따른 속도차 침전에서의 입자간 충돌특성에 관한 연구)

  • Han, Moo Young;Dock Ko, Seok;Park, Chung Hyun
    • Journal of Korean Society of Water and Wastewater
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    • v.12 no.1
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    • pp.81-87
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    • 1998
  • The possibility of collision of two particles slowly settling one after another in water can be described using the collision efficiency factor in differential sedimentation (${\alpha}_{DS}$). ${\alpha}_{DS}$ was found to be a function of several parameters particle size, particle size ratio, Hamaker constant, density of liquid and particle, gravity acceleration. Previous researches were limited to the case when there is no electric repulsion assuming that the suspension is destabilized. In this paper, ${\alpha}_{DS}$ is calculated for the stabilized condition. The relative trajectory of two particles are calculated including hydrodynamics, attraction and repulsion forces. Ionic strength and surface potential significantly affect the collision possibility of two settling particles. Depending on the surface potential and ionic strength, ${\alpha}_{DS}$ value is divided into three regions; stable, unstable and transition zone. ${\alpha}_{DS}$ increases as the ionic strength increases, and as the surface charge decreases. This result can be used to model both destabilized and stabilized suspension incorporating the collision efficiency factors of the other coagulant mechanisms such as fluid shear and Browian motion.

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Stability Assessment of an Adjacent Ground Storage Tank by Blast-induced Vibration (발파진동에 대한 인접한 지상 저장탱크의 안정성 평가)

  • Jong, Yong-Hun;Lee, Chung-In;Choi, Yong-Kun
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.16 no.1 s.106
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    • pp.19-26
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    • 2006
  • The test blasts were carried out by detonating some single blastholes at two upper sites of the underground storage cavern for the crude oil. One was performed at the entrance site of the construction tunnel and the other at the middle area of the underground storage cavern. Based on the blast-induced nitration measured by the test blasts, we suggested the propagation equations of blasting vibration that were capable of estimating the peak particle velocity. In addition, in order to assess the stability of the adjacent ground storage tank, we did the frequency analysis and the response spectrum analysis with the particle velocity-time history and the particle acceleration-time history that were measured by the test blast carried out on the entrance site of the construction tunnel. In result, it was predicted that the displacement on the highest part of the tank shell was less than the allowable displacement.

Emission Characteristics of Ultrafine particles According to Fuel Injection Type in Gasoline and LPG Vehicle (휘발유와 LPG 자동차의 연료분사방식에 따른 극미세입자 배출 특성)

  • Park, Kyoung-Gyun;Kwon, Sang-Il;Lee, Woo-Suk;Hong, Ji-Hyung
    • Journal of ILASS-Korea
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    • v.14 no.4
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    • pp.184-189
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    • 2009
  • Recently, ultrafine particles emitted from internal combustion engine is main concern because of its well known adverse health effects. So Europe decided to start the regulation about diesel engine particle number emissions. The nanoparticles smaller than 50nm in diameter have the ability to penetrate deep into interstitial tissue of luge, where they may cause severe respiratory inflammation and acute pulmonary toxicity. Recent studies have showed that spark ignition engines emit particles number concentration comparable to those from diesel engines with DPF under high load and rich mixture conditions, including cold starts and acceleration. So this study investigated emission characteristics of ultrafine particles according to fuel injection type in gasoline vehicles and LPG vehicles. The test vehicles were tested on CVS-75 and NEDC vehicle test mode using the chassis dynamometer, CPC system applied as a particle measuring instrument at the end of dilution tunnel. As a result, the correlation between fuel injection type and particulate emission was determined. GDI vehicle emitted 10 times higher particles than PFI vehicles, and compared to Mixer and LPGI type LPG vehicle, LPLI vehicle emitted particles high.

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Effect of the Replacement of Fine Particle Cement on Mechanical Properties of the Concrete (미분 시멘트의 치환율 변화가 콘크리트의 역학적 특성에 미치는 영향)

  • Choi, Sung-Yong;No, Dong-Hyun;Kim, Kyung-Min;Park, Sang-Joon;Kwan, O-Bong;Han, Min-Cheol
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2007.11a
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    • pp.133-136
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    • 2007
  • This study investigates mechanical properties of the concrete using fine particle cement which is manufactured by the pulverizing process. The variable factors are 3 types of W/C such as 40, 50, and 60%, 3 types of curing temperature such as 5, 20, and $35^{\circ}C$, and 5types of the replacement of the fine particle cement such as 0, 25, 50, 75, and 100%. The unit water content, S/a and amount of the SP and AE agents to secure the slump and air content is gradually increased in accordance with amount of replacement. It can be confirmed that the delay of the setting time depending on FC content is decreased corresponding to FC content, so the effect of the acceleration to the setting time is expected. The compressive strength corresponding to FC content is proportionally increased, and the growth is confirmed about $30{\sim}40%$ at a day in 50% of FC contents. However, the increase of the strength is gradually decreased in accordance with increasing age.

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A modified particle swarm approach for multi-objective optimization of laminated composite structures

  • Sepehri, A.;Daneshmand, F.;Jafarpur, K.
    • Structural Engineering and Mechanics
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    • v.42 no.3
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    • pp.335-352
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    • 2012
  • Particle Swarm Optimization (PSO) is a stochastic population based optimization algorithm which has attracted attentions of many researchers. This method has great potentials to be applied to many optimization problems. Despite its robustness the standard version of PSO has some drawbacks that may reduce its performance in optimization of complex structures such as laminated composites. In this paper by suggesting a new variation scheme for acceleration parameters and inertial weight factors of PSO a novel optimization algorithm is developed to enhance the basic version's performance in optimization of laminated composite structures. To verify the performance of the new proposed method, it is applied in two multi-objective design optimization problems of laminated cylindrical. The numerical results from the proposed method are compared with those from two other conventional versions of PSO-based algorithms. The convergancy of the new algorithms is also compared with the other two versions. The results reveal that the new modifications inthe basic forms of particle swarm optimization method can increase its convergence speed and evade it from local optima traps. It is shown that the parameter variation scheme as presented in this paper is successful and can evenfind more preferable optimum results in design of laminated composite structures.

A Case Study on the Stability Assessment of Structures by Blast-induced Vibration (발파진동에 대한 구조물 안정성 평가 - 지하비축기지 건설 사례)

  • Lee, Chung-In;Choi, Yong-Kun;Jong, Yong-Hun
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.11a
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    • pp.479-484
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    • 2005
  • The test blasts were carried out by detonating some single blastholes at two upper sites of the underground storage cavern the crude oil. One was performed at the entrance site of the construction tunnel and the other at the middle part of the underground storage cavern. Based on the blast-induced vibration measured by the test blasts, we suggested the propagation equations of blasting vibration that were capable of estimating the peak particle velocity. In addition, in order to assess the stability of the nearest ground storage tank, we did the frequency analysis and the response spectrum analysis with the particle velocity-time history and the particle acceleration-time history that were measured by the test blast carried out on the entrance site of the construction tunnel. In result, it was predicted that the displacement on the highest part of the tank shell was less than the allowable displacement.

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Effect of Relative Humidity, Disk Acceleration, and Rest Time on Tribocharge Build-up at a Slider-Disk Interface of HDD (HDD에서 상대습도, 디스크 가속도, 정지시간이 슬라이더-디스크 인터페이스의 마찰대전 발생에 미치는 영향)

  • Hwang J.;Lee D.Y.;Lee J.;Choa S.H.
    • Tribology and Lubricants
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    • v.22 no.2
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    • pp.59-65
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    • 2006
  • In hard disk drives as the head to disk spacing continues to decrease to facilitate recording densities, slider disk interactions have become much more severe due to direct contact of head and disk surfaces in both start/stop and flying cases. The slider disk interaction in CSS (contact-start-stop) mode is an important source of particle generation and tribocharge build-up. The tribocharge build-up in the slider disk interface can cause ESD (electrostatic discharge) damage. In turn, ESD can cause severe melting damage to MR or GMR heads. The spindle speed of typical hard disk drives has increased in recent years from 5400 rpm to 15000 rpm and even higher speeds are anticipated in the near future. And the increasing disk velocity leads to increasing disk acceleration and this might affect the tribocharging phenomena of the slider/disk interface. We investigated the tribocurrent/voltage build-up generated in HDD, operating at increasing disk accelerations. In addition, we examined the effects with relative humidity conditions and rest time. We found that the tribocurrent/voltage was generated during pico-slider/disk interaction and its level was about $3\sim16pA$ and $0.1\sim0.3V$, respectively. Tribocurrent/voltage build-up was reduced with increasing disk acceleration. Higher humidity conditions $(75\sim80%)$ produced lower levels tribovoltage/current. Therefore, a higher tribocharge is expected at a lower disk acceleration and lower relative humidity condition. Rest time affected the charge build-up at the slider-disk interface. The degree of tribocharge build-up increased with increasing rest time.