• Structural Engineering and Mechanics
• /
• 제61권1호
• /
• pp.1-13
• /
• 2017

The effectiveness of the repair scheme for the damaged captive-columns with CFRPs (Carbon Fiber Reinforced Polymer) was investigated in terms of response quantities such as strength, ductility, dissipated energy and stiffness degradation. Two 1/3 scale, one-story one-bay RC (Reinforced Concrete) frames were designed to represent the substandard RC buildings in Turkish building stock. The first one, which is the reference specimen, is the bare frame without infill wall. Partial infill wall with opening was constructed between the columns of the second frame and this caused captive column defect. Severe damage was observed with the concentration of shear cracks in the second specimen columns. Then, the damaged members were repaired by CFRP wrapping and retested. For the three test series, similar reversed cyclic lateral displacement under combined effect of axial load was applied to the top of the columns. Overall response of the bare frame was dominated by flexural cracks. Brittle type of shear failure in the column top ends was observed in the specimen with partial infill wall. It was observed that former capacity of damaged members of the second frame was recovered by the applied repair scheme. Moreover, ultimate displacement capacity of the damaged frame was improved considerably by CFRP wrapping.

• 대한화학회지
• /
• 제57권6호
• /
• pp.769-777
• /
• 2013

The effect of operating conditions (temperature and the partial pressures of H2 and CO) on the reaction rate of Fischer-Tropsch synthesis (FTS) were investigated by carrying out experiments according to a Box-Behnken design (BBD), and were mathematically modeled by using response surface methodology (RSM). The catalyst used was a nano-structured cobalt/manganese oxide catalyst, which was prepared by thermal decomposition. The rate of synthesis was measured in a fixed-bed micro reactor with $H_2/CO$ molar feed ratio of 0.32-3.11 and reactor pressure in the range of 3-9.33 bar at space velocity of $3600h^{-1}$ and a temperature range of 463.15-503.15 K, under differential conditions (CO conversion below 2%). The results indicated that in the present experimental setup, the temperature and the partial pressure of CO were the most significant variables affecting reaction rate. Based on statistical analysis the quadratic model of reaction rate of FTS was highly significant as p-value 0.0002.

• Steel and Composite Structures
• /
• 제31권2호
• /
• pp.187-199
• /
• 2019

This paper presents the semi-analytical development of the dynamic instability behavior and the dynamic response of functionally graded (FG) cylindrical shallow shell panel subjected to different type of periodic axial compression. First, in prebuckling analysis, the stresses distribution within the panels are determined for respective loading type and these stresses are used to study the dynamic instability behavior and the dynamic response. The prebuckling stresses within the shell panel are the same as applied in-plane edge loading for the case of uniform and linearly varying loadings. However, this is not true for the case of parabolic loadings. The parabolic edge loading produces all the stresses (${\sigma}_{xx}$, ${\sigma}_{yy}$ and ${\tau}_{xy}$) within the FG cylindrical panel. These stresses are evaluated by minimizing the membrane energy via Ritz method. Using these stresses the partial differential equations of FG cylindrical panel are formulated by applying Hamilton's principal assuming higher order shear deformation theory (HSDT) and von-$K{\acute{a}}rm{\acute{a}}n$ non-linearity. The non-linear governing partial differential equations are converted into a set of Mathieu-Hill equations via Galerkin's method. Bolotin method is adopted to trace the boundaries of instability regions. The linear and non-linear dynamic responses in stable and unstable region are plotted to know the characteristics of instability regions of FG cylindrical panel. Moreover, the non-linear frequency-amplitude responses are obtained using Incremental Harmonic Balance (IHB) method.

• 대한한방부인과학회지
• /
• 제35권1호
• /
• pp.91-104
• /
• 2022

Objectives: The purpose of this study is to report the effect of combination treatment of Traditional Korean medicine (TKM) and chemotherapy on a ovarian cancer with lung metastasis patient. Methods: One ovarian cancer with lung metastasis patient was treated by TKM in conjunction with Carboplatin/paclitaxel since Feb. 2020. Repeat cycle every 3 weeks for 6 times. The patient has been treated with TKM at the same time. To evaluate the patient, symptoms were measured by Numeric Rating Scale (NRS), Eastern Cooperative Oncology Group (ECOG) and tumor size was measured by scanning with Computed Tomography (CT). Blood tests including cancer biomarker were conducted during treatment. Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), version 5.0. Results: After treatment with Carboplatin/paclitaxel and TKM during 2 months, the size of the ovarian cancer was decreased(Partial Response, PR), size and malignant pleural effusion at right lung disappeared. And no evidence of newly developed metastatic lesions. After 2 months, the tumor response was stable disease while improving the performance and other symptoms. Conclusions: This case provides us conjunctive treatment with Conventional and Eastern medicine may have substantial benefit for patients with end-stage ovarian cancer.

• The Journal of Asian Finance, Economics and Business
• /
• 제7권10호
• /
• pp.51-61
• /
• 2020

The study aims to compare whether using Earnings Response Coefficient (ERC) is better than using the new concept of Accounting Earnings Response Coefficient (AERC) in determining the earnings quality response coefficient value. Also, the study seeks to explain the effect of company characteristics and corporate governance on AERC through voluntary disclosure and information asymmetry. Research samples include 69 manufacturing companies listed on the Indonesian Stock Exchange over the period 2014-2017. The data come from annual reports, stock market prices, CSPI, EPS, stock returns and market returns. The research model is tested using the structural equation model (SEM) with partial least square (PLS). The results showed the value of the earnings response coefficient produced by AERC and ERC was different. Earnings quality resulting from AERC regression by adding CFO values better reflects the actual earnings quality. These results are consistent with the concept built from the proposition about earnings quality at AERC, that quality earnings are informative accounting earnings. The theoretical findings of this study provide an explanation that operational cash flow plays a role in evaluating earnings quality, while providing reinforcement that the ERC regression model fails to detect stock market reactions to information relevant to the aggregated values of accounting earnings.

• Parasites, Hosts and Diseases
• /
• 제45권2호
• /
• pp.103-109
• /
• 2007

Leishmania tropica and L. major are etiologic agents of human cutaneous leishmaniasis. Delayed type hypersensitivity (DTH) is an immunologic response that has been frequently used as a correlate for protection against or sensitization to leishmania antigen. In BALB/c mice, L. tropica infection results in non-ulcerating disease, whereas L. major infection results in destructive lesions. In order to clarify the immunologic mechanisms of these 2 different outcomes, we compared the ability of these 2 leishmania species in induction of DTH response in this murine model. BALB/c mice were infected with L. major or L. tropica, and disease evolution and DTH responses were determined. The results show that the primary L. major infection can exacerbate the secondary L. major infection and is associated with DTH response. Higher doses of the primary L. major infection result in more disease exacerbation of the secondary L. major infection as well as higher DTH response. L. tropica infection induces lower DTH responses than L. major. We have previously reported that the primary L. tropica infection induces partial protection against the secondary L. major infection in BALB/c mice. Induction of lower DTH response by L. tropica suggests that the protection induced against L. major by prior L. tropica infection may be due to suppression of DTH response.

• Earthquakes and Structures
• /
• 제12권3호
• /
• pp.333-347
• /
• 2017

Masonry infill walls are unavoidable parts of any building to create a separation between internal space and external environment. In general, there are some prevalent openings in the infill wall due to functional needs, architectural considerations or aesthetic concerns. In current design practice, the strength and stiffness contribution of infill walls is not considered. However, the presence of infill walls may decisively influence the seismic response of structures subjected to earthquake loads and cause a different behavior from that predicted for a bare frame. Furthermore, partial openings in the masonry infill wall are significant parameter affecting the seismic behavior of infilled frames thereby decreasing the lateral stiffness and strength. The possible effects of openings in the infill wall on seismic behavior of RC frames is analytically studied by means of pushover analysis of several bare, partially and fully infilled frames having different bay and story numbers. The stiffness loss due to partial opening is introduced by the stiffness reduction factors which are developed from finite element analysis of frames considering frame-infill interaction. Pushover curves of frames are plotted and the maximum base shear forces, the yield displacement, the yield base shear force coefficient, the displacement demand, interstory drift ratios and the distribution of story shear forces are determined. The comparison of parameters both in terms of seismic demand and capacity indicates that partial openings decisively influences the nonlinear behavior of RC frames and cause a different behavior from that predicted for a bare frame or fully infilled frame.

• The Korean Journal of Physiology and Pharmacology
• /
• 제16권1호
• /
• pp.59-64
• /
• 2012

Hypoxic pulmonary vasoconstriction (HPV) is physiologically important response for preventing mismatching between ventilation and perfusion in lungs. The HPV of isolated pulmonary arteries (HPV-PA) usually require a partial pretone by thromboxane agonist (U46619). Because the HPV of ventilated/perfused lungs (HPV-lung) can be triggered without pretone conditioning, we suspected that a putative tissue factor might be responsible for the pretone of HPV. Here we investigated whether HPV can be also observed in precision-cut lung slices (PCLS) from rats. The HPV in PCLS also required partial contraction by U46619. In addition, $K^+$ channel blockers (4AP and TEA) required U46619-pretone to induce significant contraction of PA in PCLS. In contrast, the airways in PCLS showed reversible contraction in response to the $K^+$ channel blockers without pretone conditioning. Also, the airways showed no hypoxic constriction but a relaxation under the partial pretone by U46619. The airways in PCLS showed reliable, concentration-dependent contraction by metacholine ($EC_{50}$, ~210 nM). In summary, the HPV in PCLS is more similar to isolated PA than V/P lungs. The metacholineinduced constriction of bronchioles suggested that the PLCS might be also useful for studying airway physiology in situ.

• 한국통신학회논문지
• /
• 제27권8A호
• /
• pp.739-752
• /
• 2002

부분 응답 신호 기법은 데이터 전송 및 저장 채널에서 신호간 간섭을 효율적으로 제어함으로써 주파수 대역폭 감축의 목적을 달성할 수 있어 많이 채택하고 있는 기법이다. 본 논문에서는 부분 응답 채널 시스템에서의 채널 등화의 문제를 연구하였다. 부분 응답 모델의 대상으로 자기 기록 채널을 고려하였는데 적응 등화기 설계를 위한 기준 신호의 서로 다른 선택이 등화기 성능에 미치는 영향을 연구하였다. 먼저 각각의 등화기에 대해서 기존의 등화기 설계에서 사용하고 있는 등화기 출력 단에서의 평균제곱오차를 이론적으로 분석하였다. 한편 등화기 출력 단에서의 평균제곱오차는 등화기 자체 분석에 있어서는 유용하지만 서로 다른 등화기법의 비료에는 미흡하기 때문에 이를 보완하기 위한 성능 평가 요소로서 최종 데이터 검출 직전에서의 데이터 평균제곱오차를 이론적으로 유도하였다. 이 결과를 통해 부분 응답 시스템에서 서로 다른 신호 배치를 갖는 적응 등화 기법들의 성능 비교가 가능하다. 또한 이러한 성능 평가 기준에 적합한 등화기 설계 방법도 고려하였다. 마지막으로 컴퓨터 시뮬레이션 결과를 통해 이론적으로 분석된 연구 결과의 타당성을 입증하였다.

• Structural Engineering and Mechanics
• /
• 제14권3호
• /
• pp.345-364
• /
• 2002

The scaling laws for vibration response of anti-symmetrically laminated plates are derived by applying the similitude transformation to the governing differential equations directly. With this approach, a closed-form solution of the governing equations is not required. This is a significant advantage over the method employed by other researchers where similitude transformation is applied to the closed-form solution. The scaling laws are tested by comparing the similitude fundamental frequencies to the theoretical fundamental frequencies determined from the available closed-form solutions. In case of complete similitude, similitude solutions from the scaling laws exactly agree with the theoretical solutions. Sometimes, it may not be feasible to select the model which obeys the similarity requirement completely, therefore partial similitude is theoretically investigated and approximate scaling laws are recommended. The distorted models in stacking sequences and laminated material properties demonstrate reasonable accuracy. On the contrary, a model with distortion in fiber angle is not recommended. The derived scaling laws are very useful to determine the vibration response of complex prototypes by performing the experiment on a model with required similarities.