• Title/Summary/Keyword: Park je sang

Search Result 635, Processing Time 0.034 seconds

Expression Patterns of Germ Cell-specific Phosducin-like 2 during Testicular and Ovarian Development in Chickens

  • Zheng, Ying Hui;Rengaraj, Deivendran;Park, Kyung-Je;Lee, Sang-In;Han, Jae-Yong
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.23 no.8
    • /
    • pp.1000-1006
    • /
    • 2010
  • Phosducin (PDC) is a photoreceptor cell-specific protein that is phosphorylated by cyclic nucleotide-dependent protein kinase. PDC and PDC-like proteins (PDCL, PDCL2, and PDCL3) are members of a conserved family of small thioredoxin-like proteins that modulate the ${\beta}$- and ${\gamma}$-subunits of G-proteins. In mammals, Pdc, Pdcl, and Pdcl3 genes show ubiquitous expression; however, Pdcl2 gene expression is limited to the testis and ovary. The aim of the present study was to examine the expression patterns of chicken Pdcl2 (cPdcl2) during testicular and ovarian development. Protein sequence comparisons performed using the CLUSTAL X program revealed that the amino acid sequences and potential phosphorylation sites of cPDCL2 and mammalian PDCL2 proteins were highly conserved. Quantitative real-time PCR analysis revealed that cPdcl2 was differentially expressed in the testis and ovary. Specifically, cPdcl2 expression was detected at low levels in the ovary at all time points. In the testis, cPdcl2 expression was detected at low levels until 5 weeks of age. At 8 weeks of age, however, cPdcl2 showed increased expression levels in the testis. Using in situ hybridization, we detected high levels of cPdcl2 expression in the testis, particularly in the spermatocytes and round spermatids. In summary, our data describe expression patterns of germ cell-specific Pdcl2 during testicular and ovarian development in chickens.

The p90rsk-mediated signaling of ethanol-induced cell proliferation in HepG2 cell line

  • Kim, Han Sang;Kim, Su-Jin;Bae, Jinhyung;Wang, Yiyi;Park, Sun Young;Min, Young Sil;Je, Hyun Dong;Sohn, Uy Dong
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.20 no.6
    • /
    • pp.595-603
    • /
    • 2016
  • Ribosomal S6 kinase is a family of serine/threonine protein kinases involved in the regulation of cell viability. There are two subfamilies of ribosomal s6 kinase, (p90rsk, p70rsk). Especially, p90rsk is known to be an important downstream kinase of p44/42 MAPK. We investigated the role of p90rsk on ethanol-induced cell proliferation of HepG2 cells. HepG2 cells were treated with 10~50 mM of ethanol with or without ERK and p90rsk inhibitors. Cell viability was measured by MTT assay. The expression of pERK1, NHE1 was measured by Western blots. The phosphorylation of p90rsk was measured by ELISA kits. The expression of Bcl-2 was measured by qRT-PCR. When the cells were treated with 10~30 mM of ethanol for 24 hour, it showed significant increase in cell viability versus control group. Besides, 10~30 mM of ethanol induced increased expression of pERK1, p-p90rsk, NHE1 and Bcl-2. Moreover treatment of p90rsk inhibitor attenuated the ethanol-induced increase in cell viability and NHE1 and Bcl-2 expression. In summary, these results suggest that p90rsk, a downstream kinase of ERK, plays a stimulatory role on ethanol-induced hepatocellular carcinoma progression by activating anti-apoptotic factor Bcl-2 and NHE1 known to regulate cell survival.

An Estimator Design of Turning Acceleration for Tracking a Maneuvering Target using Curvature (곡률을 이용한 기동표적 추적용 회전가속도 추정기 설계)

  • Joo, Jae-Seok;Park, Je-Hong;Lim, Sang-Seok
    • Journal of Advanced Navigation Technology
    • /
    • v.4 no.2
    • /
    • pp.162-170
    • /
    • 2000
  • Maneuvering targets are difficult for the Kalman filter to track since the target model of tracking filter might not fit the real target trajectory and the statistical characteristics of the target maneuver are unknown in advance. In order to track such a wildly maneuvering target, several schemes had been proposed and improved the tracking performance in some extent. In this paper a Kalman filter-based scheme is proposed for maneuvering target tracking. The proposed scheme estimates the target acceleration input vector directly from the feature of maneuvering target trajectories and updates the simple Kalman tracker by use of the acceleration estimates. Simulation results for various target profiles are analyzed for a comparison of the performances of our proposed scheme with that of conventional trackers.

  • PDF

Design Standard of Activated Carbon Vessel for the Intermittent Emission Sources of Volatile Organic Compounds (휘발성 유기화합물의 간헐적 배출원에 대한 활성탄 흡착 시스템 설계기준)

  • Lee, Si-Hyun;Lim, Jeong-Whan;Rhim, Young-Jun;Kim, Sang-Do;Woo, Kwang-Je;Son, Mi-Sook;Park, Hee-Jae;Seo, Man-Cheol;Ryu, Seung-Kon
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.23 no.2
    • /
    • pp.250-260
    • /
    • 2007
  • It was investigated that the emission characteristics of volatile organic compounds (VOCs) from small and medium companies located on industrial complexes in Metropolitan area. The emission characteristics are intermittent sources in which VOCs emissions are highly depends on the working condition. Optimized ventilation system to improve air quality in working area for the three typical companies were installed. Adsorption characteristics of major VOCs such as MEK, IPA, and toluene emitted front the companies were investigated for design of the activated carbon vessel as a VOCs control facility in each company. Concentration of total hydrocarbon and gas amounts needed to ventilation were also used as a design parameter. Mixed adsorbent to improve adsorption characteristics of problematic solvents like IPA and the design guideline of the activated carbon vessel have been suggested.

Study of the journalists job stress to Emotional exhaustion and the Physical symptoms effect -journalists in Seoul- (언론인의 직무 스트레스가 정서적 탈진과 신체적 증상에 미치는 영향에 관한 연구 -서울시 언론인을 중심으로-)

  • Park, Sang-Young;Cho, Sung-Je
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.6
    • /
    • pp.3548-3556
    • /
    • 2014
  • The purpose of this study was to establish the basis for the smooth business conduction of journalists by identifying the impact of job stress on the emotional exhaustion and physical symptoms. The subjects of the survey were 124 journalists of the editorial department of 11 daily newspaper companies in Seoul and the reference period of the survey was from May 1, 2013 to Aug 31, 2013. Factor analysis, correlation analysis and multiple regression analysis were performed using SPSS Win 18.0 at the 0.05 significance level. According to the study, emotional exhaustion is related to 'excessive quantitative role'(r=.613, p<.001) and 'role conflict'(r=.0195, p<.05) and the physical symptoms are related to 'excessive quantitative role'(r=.219, p<.05) and 'career management'(r=.529, p<.001). The results may provide implications for arranging a health promotion program handling job stress.

Journalists, according to the demographic characteristics of the physical symptoms and emotional exhaustion -Study of Seoul journalists- (언론인의 인구사회학적 특성에 따른 신체적 증상과 정서적 탈진 -서울시 언론인을 중심으로-)

  • Park, Sang-Young;Cho, Sung-Je
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.14 no.12
    • /
    • pp.6218-6226
    • /
    • 2013
  • The aim of this study was to determine the basis for smooth conduction of business for journalists by identifying the journalists demographic characteristics and the relevance of the physical symptoms and emotional exhaustion. The surveys were carried out from 2013 May 1 to August 31 and the subjects of the surveys were 124 journalists working in the editorial part of 11daily newspaper companies located in Seoul. For data analysis, frequency analysis, factor analysis, and a T-test were performed using the SPSS Win 18.0 program. A p value 0.05 was considered significant. The study showed that there were significant differences in the physical symptoms depending on sex, age, marital status, and rank. In addition, emotional exhaustion was affected by gender, age and Sunday duty cycle etc. The results of this study will provide basic data for preparing a physical and mental health promotion program for journalists by the demographic characteristics.

Enhanced Electron Emission of Carbon Nanotube Arrays Grown Using the Resist-Protection-assisted Positioning Technique

  • Ryu, Je-Hwang;Kim, Ki-Seo;Yu, Yi-Yin;Lee, Chang-Seok;Lee, Yi-Sang;Jang, Jin;Park, Kyu-Chang
    • Journal of Information Display
    • /
    • v.9 no.4
    • /
    • pp.30-34
    • /
    • 2008
  • Field emitter arrays (FEAs) were developed using carbon nanotubes (CNTs) as electron emission sources. The CNTs were grown using a selective-positioning technique with a resist-protection layer. The light emission properties were studied through the electron emission of the CNTs on patterned islands, which were modulated with island diameter and spacing. The electron emission of CNT arrays with $5{\mu}m$ diameters and $10{\mu}m$ heights increased with increased spacing (from $10{\mu}m$ to $40{\mu}m$). The electron emission current of the $40-{\mu}m$-island-spacing sample showed a current density of 1.33 mA/$cm^2$ at E = 11 V/${\mu}m$, and a turn-on field of 7 V/${\mu}m$ at $1{\mu}A$ emission current. Uniform electron emission current and light emission were achieved with $40{\mu}m$ island spacing and $5{\mu}m$ island diameter.

Fine Directional De-interlacing Algorithm (정교한 방향성을 고려한 디인터레이싱 알고리즘)

  • Park, Sang-Jun;Jin, Soon-Jong;Jeong, Je-Chang
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.32 no.3C
    • /
    • pp.278-286
    • /
    • 2007
  • In this paper, an efficient algorithm is proposed for the interpolation of interlaced images. First of all, by efficiently estimating the directional spatial correlations of neighboring pixels, increased interpolation accuracy can be achieved. And then using the gradient vector which was obtained by Sobel operation, enables to consider the fine directional edges and make it possible to estimate the accurate direction of edges. In other words, it is possible to interpolate the interlaced images with considering the characteristics of images. In addition, by altering the conventional edge detector for the purpose of a easy De-interlacing and multiplying the optimal translation coefficients to each of the gradient vectors, an efficient interpolation for images can be achieved. Comparing with the conventional De-interlacing algorithms, proposed algorithm not only reduced the complexity but also estimated the accurate edge direction and the proposed scheme have been clearly verified that it enhances the objective and subjective image quality by the extensive simulations for various images.

Assessment of Ecological Grade Based on Polychaete Fauna in the Western and Southern Coast of Korea (우리나라 서·남해안에서 출현하는 다모류를 통한 해역의 생태등급 산정)

  • Paik, Sang-Gyu;Park, Heung-Sik;Yun, Sung Gyu;Je, Jong-Geel
    • Journal of Wetlands Research
    • /
    • v.7 no.2
    • /
    • pp.89-104
    • /
    • 2005
  • This study examined ecological grade of tidal flats at 59 sites along the west and east coast of Korea from January 1998 to December 2002. Assessment of ecological grade based on 7 headings includes biological and human geographical factors, such as species diversity and richness, utility value of species, possibility of damage and reservation conditions of coastline. Total of 181 species with 37 families of 14 orders were listed in this study. The highest scores (ecological grade I) showed at these five sites, Hagampo in Chungnam, Ui-do and Geomun-do in Jeonnam, Bijin-do and Maemul-do in Gyungnam. Half of thestudy sites belong to ecological grade II and 19 sites showed ecological grade III. Singyeong in Gyeonggi, Janghang in Chungnam, Gyehwado and Gomso in Jeonbuk, Dadepo in Busan were assessed as ecological grade IV. Grade V (the worst) was not found in this study.

  • PDF

Arteriovenous Fistula between Renal Artery and Inferior Vena Cava following Penetrating Abdominal Trauma; A Case Report (자상 후 발생한 신동맥과 하대정맥간 정맥루)

  • Kim, Joong Suck;Go, Seung Je;Kim, Ji Dae;Sul, Young Hoon;Ye, Jin Bong;Park, Sang Soon;Ku, Gwan Woo;Kim, Yeong Cheol
    • Journal of Trauma and Injury
    • /
    • v.28 no.4
    • /
    • pp.262-265
    • /
    • 2015
  • An arteriovenous fistula (AVF) from the renal artery following a penetrating abdominal trauma is not common. We report the case of a 19-year-old male who presented with a knife stab wound in the right upper quadrant. Due to unstable vital signs and to the protrusion of the mesentery through the stab wound, providing definite evidence of peritoneal violation, an emergent exploratory laparotomy was carried out. There were injuries at the proximal transverse mesocolon and the second portion of the duodenum, with bile leakage. There was also a mild amount of retroperitoneal hematoma near the right kidney, without signs of expansion or pulsation. The mesocolon and the duodenum were repaired. After the operation, abdominal computerized tomography (CT) was performed, which revealed contrast from the right renal artery shunting directly into the vena cava. Transcatheter arterial embolization with a coil and vascular plug was performed, and the fistula was repaired. The patient recovered completely and was discharged without complication. For further and thorough evaluation of an abdominal trauma, especially one involving the retroperitoneum, a CT scan is recommended, when possible, either prior to surgery or after surgery when the patient is stabile. Furthermore, a lateral retroperitoneal hematoma and an AVF after a penetrating trauma may not always require exploration. Sometimes, it may be safely treated non-operatively or with embolization.

  • PDF