• Radiation Oncology Journal
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• 제37권4호
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• pp.249-253
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• 2019

Purpose: We aimed to analyze the trend in intensity-modulated radiation therapy (IMRT) use in Korea from 2011 to 2018. Materials and Methods: We collected data from the Health and Insurance Review and Assessment Service (HIRA) big data based on the National Health Insurance Service claims and reimbursements records using primary treatment planning codes (HD 041) for IMRT from 2011 to 2018. We analyzed the changing patterns in clinical application to specific tumor sites and regional differences in IMRT utilization. Results: The use of IMRT has exhibited an 18-fold steep rise from 1,921 patients in 2011 to 34,759 in 2018. With regard to IMRT in 2018, 70% of patients (24,248/34,759) were treated in metropolitan areas (Seoul, Incheon, and Gyeonggi Province). IMRT was most commonly used to treat breast, lung, and prostate cancers in 2018. Among these, the use of IMRT for breast cancer shows the most remarkable increase from 2016 when the National Health Insurance began to cover IMRT for all solid tumors. Conclusion: The use of IMRT is steadily increasing to treat cancer and is concentrated in metropolitan areas.

• 정보관리학회지
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• 제30권4호
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• pp.93-110
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• 2013

정보에 대한 접근을 증가시키는 기술의 사용은 지난 십 년 동안 대학도서관 서비스에 많은 변화를 가져왔다. 정보공유공간의 등장은 이러한 변화 중 하나이다. 이에 대한 대부분의 이전 연구는 이의 개념이나 역할에 치중하였다. 반면, 정보공유공간을 공간서비스로 파악하고 있는 본 연구의 목적은 정보공유공간이 이용자 유동패턴과 도서관인식에 어떤 영향을 미치는지 파악하는데 있다. 정보공유공간이 도서관의 주요 공간과 시설로 자리매김하였고 이에 따라 이들이 이용자의 행위와 인식에 어떤 영향을 미치는지 알아볼 필요가 있다. 본 연구는 두 가지의 연구방법을 사용하였다. 첫째, 관찰법을 사용하여 이용자들의 유동 패턴 및 행위를 관찰하였고, 둘째, 정보공유공간에 대한 이용과 인식에 관한 인터뷰를 20명의 학부학생과 12명의 대학원생을 대상으로 수행하였다. 본 연구의 결과로서 학부학생과 대학원생은 서로 차별화 되는 유동패턴을 보였고, 시설의 위치와 구조는 이용자들의 움직임과 행위에 영향을 미쳤으며, 또한 정보공유공간에 대한 인식은 도서관 전반에 대한 인식으로 해석되는 경향을 보였다. 본 연구결과는 이용자 요구를 고려한 도서관 공간 설계 및 향상에 도움이 될 것이다.

• BMB Reports
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• 제40권1호
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• pp.119-124
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• 2007

Adenoviral vectors are among the most promising vectors available for human gene therapy. However, the use of recombinant adenoviral vectors, including replicationcompetent adenovirus (RCA), raises a variety of safety concerns in relation to the development of new therapies based on gene therapy. To examine how organic compounds change in rat plasma following the injection of adenovirus, $\beta$-galactosidase expressing recombinant adenovirus (designated rAdLacZ) or RCA, we investigated the content of fatty acids (FAs), which are important biochemical indicators in pathological conditions. Pattern recognition analysis on the level of FAs in rat plasma is described for the visual discrimination of adenovirus infection groups from normal controls. Plasma FAs from four control rats (normal group), and from four rats with rAdLacZ infection and six rats with RCA infection (the two abnormal groups), were examined by gas chromatography-mass spectrometry in selected ion monitoring modes as their tert-butyldimethylsilyl derivatives. In total, 20 FAs were positively detected and quantified. The results of the Student's t-test on the normal mean of two abnormal groups, the levels of three FAs (p<0.05) from rAdLacZ group and eleven FAs (p<0.05) from RCA group were significantly different. When star symbol plotting was applied to the group mean values of 20 FAs after normalization to the corresponding normal mean values, the resulting eicosagonal star patterns of the two infected groups were distorted into similar shapes, but were distinguishable from each other. Thus, these approaches will be useful for screening and monitoring of diagnostic markers for the effects of infection following the use of adenoviral vectors in gene therapy.

• 한국경제지리학회지
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• 제10권4호
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• pp.427-443
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• 2007

본 연구의 목적은 현재 서울시를 포함한 수도권 지역에서 가장 높은 수송분담율을 차지하고 있는 지하철망 상 통행흐름의 시 공간적 구조를 밝히고, 그러한 통행흐름과 토지이용의 관계성을 밝히는 것이다. 특히 본 연구에서는 지난 2004년 7월 이후 수도권 대중교통이용자의 대부분이 이용하고 있는 교통카드 통행거래자료 중 매년 주중 하루치의 통행 트랜잭션 데이터베이스에 대하여 데이터마이닝 기법을 적용하여 지난 4년간 수도권 지하철망 상 통행흐름의 위상학적 구조를 비교분석하였다. 또한 하루 중 시간대별 통행흐름의 공간적 특징을 분석하기 위하여 하루를 아침 출근시간대, 낮 시간대, 저녁 퇴근 시간대로 나누어 수도권 지하철망 상의 각 지하철역의 시간대별 출발통행량과 도착통행량을 산출하고, GIS를 이용하여 그 공간적 패턴을 비교한 결과 시간대별로 확연한 차이가 나타남을 확인하였다. 그리고 지하철 통행흐름의 위상학적 구조와 토지이용과의 관계성을 밝히기 위하여 각 지하철역의 시간대별 출발 도착 통행량과 그 지하철역 주변지역의 토지이용상태를 반영하는 지리적 변수들 간의 상관관계분석과 다중회귀분석을 실시하였으며, 분석 결과 시간대별 출발 통행량 및 도착 통행량 관계를 설명하는 선형 대수식을 도출하였다. 함수식의 적합성 판명을 위하여 공선성진단과 이분산성분석을 실시하였다.

• Journal of Preventive Medicine and Public Health
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• 제37권2호
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• pp.150-156
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• 2004

Objectives : To investigate the utilization patterns of non-steroidal anti-inflammatory drugs (NSAIDs) among the elderly with osteoarthritis (OA) undergoing primary ambulatory care in Busan metropolitan city, Korea. Methods : OA patients, aged 65 years and over, were identified from the Korean National Health Insurance Review Agency drug prescription database. The subjects had at least one episode of claim for OA (ICD-10-CM: M15-M19) between August 1, 2000 and February 28, 2002. Trends in the determinations of NSAIDs utilization were identified using chi-squared tests for trend. Results : There were 47,711 osteoarthritic patients. The total number of visits by these patients was 177,443, with a total frequency for NSAID prescriptions of 214,952. Seventy-nine percent of the OA patients were female. NSAIDs were prescribed on 133,284 visits (75.1%) and the proportion of prescriptions was significantly increased with age. Only the proportion of visit when NSAIDs were prescribed decreased, from 65.1 to 43.5%, during the study period (p<0.001). However, the proportion of combined treatments with anti-ulcer drugs was increased. The use of NSAIDs injections was decreased. Of the individual NSAIDs, diclofenac (28.7% of total frequency of NSAID prescriptions), piroxicam (15.0%) and talniflumate (8.7%), were the most frequently prescribed. Among the NSAIDs prescribed OA visits, 45.7% used two or more NSAIDs. Conclusion : The total proportion of NSAIDs prescribed to the osteoarthritic patients was higher than in other studies. The decline in the use of NSAIDs during the study period, and the frequent selection of safer medications, such as combination therapy with anti-ulcer drug, may reflect the risk awareness of the use of NSAIDs.

• 정보관리학회지
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• 제36권1호
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• pp.295-313
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• 2019

본 연구의 목적은 이용자의 스마트폰 무선신호를 이용하여 이용자가 공공도서관 공간을 어떻게 이용하는지에 대한 이용행태를 분석하는 것이다. 공간이용 데이터를 수집하는 방법으로 이용자의 스마트폰 무선신호를 감지하여 이용자의 동선을 추적하였고 수집된 데이터를 로데이터로 하여 추가적인 분석을 진행하였다. 서울시내 한 구립도서관에서 4개월 동안 수집된 이용자 공간이용 데이터를 분석한 결과, 전월 대비 평균 37.9%의 이용자들이 익월에도 이용을 하는 것으로 나타났고 이용자 중의 50%는 7분 미만으로 도서관에 머무는 것으로 나타났다. 또한 도서관을 이용하는 시간을 분석한 결과, 오후 2-3시 사이에 이용자들이 가장 많았으며 주말 오후 5시 이후에는 이용자가 매우 적게 나타났다. 층간 공간이동을 분석한 결과, 서가가 위치한 3층과 4층 사이의 공간이동이 유사하게 높게 나타났다. 이러한 결과는 스마트폰 무선신호를 이용한 도서관 공간이용행태를 분석하는 방법론이 기존에 주로 사용되었던 관찰을 통한 분석보다 효과적임을 제시하고 있다. 따라서 향후 도서관 공간이용 분석에 적극 활용된다면 도서관 공간운영의 활용성을 높일 것으로 기대된다.

• 환경영향평가
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• 제6권2호
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• pp.61-80
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• 1997

This study tried to propose the guidelines for the ecological preservation zoning in Korea. So some related laws and regulations were inspected, which were Natural Environment Preservation Act, Nature Park Act, Cultural Asset Conservation Act, Forest Act and Urban Planning Act. In these acts, I could find several concepts related to the ecosystem that are described as the protection area. But there aren't detailed and practical characteristics in those concepts. So for making the practical concept of ecosystem preservation, I considered Multiple Use Module, Wildlife habitat model, and Environmental evaluation model. Thorough this step, the process and methodology was established for evaluating and analysing. The potentiality of the GIS system was inspected. So the TM5 scene of the site was acquired and processed by ER-Mapper, Idrisi, Arc/Info and Arcview. And several digitized data were input by scanning and vecterizing. The Erdas format was mostly exchangeable to any program. The site is the Byonsan Peninsula National Park. The forest stand information and topographic data were digitized, types of which are forest year, DBH, density, slope, aspect etc. And also the watershed boundary, roads and paths, natural and cultural resources were mapped and analysed. Modelling of preservation suitability found the dispersed patterns for the best suitable zone through all the site. And the development potential areas were checked on downwatershed. This patterns are thought to result from the forest location for the wildlife habitat and the low altitude and no-steep slopes for developing. And Early warning system concept was introduced by overlapping these two patterns on the both potential area. As the conclusions, I proposed that the preservation zone be assigned according to the watershed unit as the main ecosystem zone. This main area should be linked by the eco-corridor through the point type eco-system. Finally, I thought the comprehensive information system should be established for making the rational and efficient decision making in natural area.

• 한국광학회지
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• 제8권2호
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• pp.169-173
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• 1997

가로.세로의 비가 큰 광도파로 소자 제작용 마스크 제작에는 레이저 리소그래피 장치가 기존의 리소그래피 장치에 비해 비용면 등을 고려하면 많은 장점을 가지고 있다. 레이저 리소그래피 장치를 이용 보편적인 양극형 마스크는 물론 기존의 레이저 리소그래피 장치로는 제작하기에 많은 어려움이 있는 음극형 마스크를 포토레지스트의 인위적 변화를 이용 제작할 수 있었다. 제안된 방법은 주변환경 즉 먼지, 장치의 진동 그리고 레이저 입사광 변화 등에 기존의 장치 보다 덜 민감함을 실험적으로 확인하였다. 이 방법을 이용 광도파로 소자의 기본을 이루는 S형태 곡선으로 구성된 광분배기 패턴을 제작하였으며, 제작된 패턴의 대비 및 재현성에 있어서 그 특성이 매우 우수함을 실험적으로 확인하였다.

• Journal of the Optical Society of Korea
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• 제18권5호
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• pp.569-573
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• 2014

We demonstrate a low-cost, superbly efficient way of etching for the nano-, and micro-sized pyramid patterns on (100)-oriented Si wafer surfaces for use as a patterned master. We show a way of producing functional optical films for the viewing angle direction brightness-enhancement of Lambertian LED (light emitting diode)/OLED (organic light emitting diode) planar lighting applications. An optimally formulated KOH (Potassium hydroxide) wet etching process enabled random-positioned, and random size-distributed (within a certain size range) pyramid patterns to be developed over the entire (100) silicon wafer substrates up to 8" and a simple replication process of master patterns onto the PC (poly-carbonate) and PMMA (poly-methyl methacrylate) films were performed. Haze ratio values were measured for several film samples exhibiting excellent values over 90% suitable for LED/OLED lighting purposes. Brightness was also improved by 13~14% toward the viewing angle direction. Computational simulations using LightTools$^{TM}$ were also carried out and turned out to be in strong agreement with experimental data. Finally, we could check the feasibility of fabricating low-cost, large area, high performance optical films for commercialization.

• 패션비즈니스
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• 제10권1호
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• pp.20-30
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• 2006

Aprons are popularly used among women for domestic work. They also protect clothes from filth and at the same time become an ornamentation for fashion. Despite their important use at homes and restaurants, beauty parlors, and hotels, little study has been done on aprons. Commercialized aprons do not come in various forms, rather they use the same simple shape with different patterns. There has been no independent study done on aprons, however aprons have been studied as a part of uniform studies in the dining industry by Park and Na(2003) and uniform studies in the airline industry by Lee(2001) and Chung(2001). In this study, the author looked into aprons in accordance to the change of housing space and life style. Not only to be worn in the kitchen, but also to greet guests or for a walk in the neighborhood, the apron needs to have various functions and a trendy fashion. Designs to persue personality and high quality along with functionality and esthetical beauty were developed to present various functions of the apron.