• 대한두경부종양학회지
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• 제12권1호
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• pp.58-64
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• 1996

The parathyroid adenoma is the most common cause of the primary hyperparathyroidism. The characteristic of primary hyperparathyroidism is hypercalcemia and high value of serum parathyroid hormone. The primary hyperparathyroidism with parathyroid adenoma is treated by excision of parathyroid gland involved. Especially, parathyroid storm in patients with primary hyperparathyroidism is more prevalent than commonly appreciated. The symptoms and signs of the syndrome are not only due to the hypercalcemia, but also to the toxic effects of the parathyroid hormone. Its wide, but nonspecific clinical presentations make it easily confused with other cardiovascular or renal diseases. The mortality rate in untreated cases of parathyroid storm is essentially 40%. A 33 year old woman with primary hyperparathyroidism was found to have a left lower parathyroid adenoma, presented with hypercalcemic crisis. Initially, good responsiveness to a saline infusion, furosemide administration was noted. Unfortunately, she became consciousness disturbance after fine-needle aspiration of the parathyroid tumor. The recurrent storm was refractory to medical therapy, but was treated succesfully by emergent surgical removal tumor revealed a parathyroid adenoma with parathyroid hormone. Hypercalcemia was alleviated postoperatively. These observations corroborated a functioning parathyroid adenoma.

• Journal of Chest Surgery
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• 제36권1호
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• pp.59-62
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• 2003

종격동에 발생하는 부갑상선 낭종은 매우 드문 질환으로 대부분 우연히 발견되어 진다. 수술적 절제가 필요하며, 전 절제가 된 경우 재발은 매우 드물다. 71세 남자 환자로 단순 흉부 촬영상 우연히 발견된 6$\times$5 cm 크기의 우측 상부 종격동 종괴로 내원하였다. 추가 검사 후 수술적 절제를 시행하였으며, 절제된 종괴는 조직학적으로 종격동에 발생한 부갑상선 낭종으로 진단 되었다. 수술 후 재발 없이 4개월째 외래 관찰중이다. 저자들은 종격동 부갑상선 낭종 1례를 치험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 대한두경부종양학회지
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• 제15권2호
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• pp.235-238
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• 1999

Parathyroid carcinoma is rare, occurring in less than 2-3% of the patients with primary hyperparathyroidism. In the patients with chronic renal failure, the incidence is extremely low. Only 13 cases of parathyroid carcinoma with chronic renal failure have been described in the world literature. We report a case of parathyroid carcinoma in a 43-year-old man who has been suffered from chronic renal failure for 19 years. To our knowledge, this is the first case of parathyroid carcinoma occurring in the thyroid gland associated with secondary hyperparathyroidism.

• 대한핵의학회지
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• 제35권4호
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• pp.274-279
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• 2001

A large superior mediastinal mass was found incidentally by ultrasonography in a 60-year-old man. There was an abnormal accumulation of Tl-201 in the lower pole of left thyroid gland, extending into left superior mediastinum on Tc-99m pertechnetate/Tl-201 subtraction scan. Laboratory findings relating thyroid and parathyroid were all within normal range. We considered the mass as a non-functioning parathyroid adenoma tentatively. However, subsequent surgery and pathologic examination revealed the mass to be a benign mixed thymoma. We report a case of patient with thymoma showing unusual Tc-99m pertechnetate/Tl-201 subtraction imaging and laboratory findings, and suggest to consider the possibility of other mediastinal tumors rather than parathyroid adenoma.

• 대한두경부종양학회지
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• 제25권2호
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• pp.174-177
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• 2009

Parathyroid cyst are rare lesion of the neck and superior mediastinum. They are classified as either functional or nonfunctional based on the presence or absence of hyperparathyroidism. They typically present as a palpable neck mass, or as an incidental finding during neck surgery. So, it must be included within the differential diagnosis of a neck lump. A 48-year old woman was admitted to our hospital for evaluation of left anterior neck mass. Physical finding showed soft, movable, non-tender mass on the lower left third of the neck. Laboratory findings revealed normal thyroid function and normal serum calcium level. On previous history, patient underwent two times sono-guided fine needle aspiration at local clinic, and about 10cc clear watery aspirate was noted. Computerized tomography findings showed non-enhancing hypodense cystic lesion on left thyroid area with tracheal deviation to right side. Preoperative diagnosis was thyroid cyst, and thyroidectomy was planed. Intra-operative finding showed huge cystic mass occupying the left thyroid area and smooth, shiny, semitransparent thin cyst wall was noted, which was loosely attached to the thyroid. The cyst was easily dissected free from the thyroid and surrounding tissues. After cyst removal, pathological study confirmed as a parathyroid cyst.

• 대한영상의학회지
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• 제84권3호
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• pp.596-605
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• 2023

목적 이 연구는 갑상선 수술 중 절제된 정상 부갑상선 검체를 이용하여 부갑상선의 초음파 소견을 알아보고자 한다. 대상과 방법 2020년 12월부터 2021년 3월까지 갑상선 수술을 시행한 17명 환자의 34개 부갑상선을 분석하였다. 모든 정상 부갑상선은 자가이식전 동결 절편을 통해 조직학적으로 진단되었고 부갑상선 검체를 무균 생리식염수에 넣은 상태에서 고해상 초음파 영상을 얻었다. 부갑상선 검체의 초음파 에코(고에코, 저에코), 에코결(균일, 불균일), 크기, 및 모양(난원, 원형)을 후향적으로 분석하였다. 두 명의 환자에서 얻은 3개의 부갑상선 에코를 절제된 갑상선 실질 에코와 비교하였다. 결과 모든 부갑상선은 생리식염수에 적신 거즈의 에코와 유사한 고에코를 나타냈다. 균일한 고에코는 32개(94.1%)의 부갑상선에서 관찰되었고 3개의 부갑상선은 갑상선 실질보다 높은 에코를 나타냈다. 부갑상선의 장경은 5.1-9.8 mm (평균 7.1 mm)였고, 모양은 33개(97.1%)부갑상선에서 난원형을 보였다. 결론 부갑상선 검체의 에코는 모두 고에코를 나타냈고, 작은 크기의 균일한 고에코를 보이는 난원형 구조물은 부갑상선의 특징적 초음파 소견이었다.

• Journal of Breast Cancer
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• 제21권4호
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• pp.463-467
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• 2018

Metastasis from primary cancer to the thyroid is uncommon in breast cancer. Here we present a case of lobular breast carcinoma that metastasized to the thyroid. A 54-year-old woman without symptoms was admitted to our institution for staging of the lymph node above the left clavicle. An $^{18}F$-fluoro-deoxy-D-glucose positron emission tomography scan was performed for staging, and low uptakes were observed in the left supraclavicular and cervical lymph nodes. High uptake was seen in the posterior and lower left lobe of the thyroid. Histologic findings indicated lobular breast carcinoma (positive GATA3, loss of E-cadherin expression) metastatic to the thyroid with a luminal profile. Immunohistochemical analysis was negative for primary thyroid or parathyroid carcinoma. To our knowledge, this is the first report of a patient presenting a metastatic invasive lobular carcinoma in the thyroid and lymph nodes without a prior diagnosis of breast cancer.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제20권3호
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• pp.241-245
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• 1998

The plunging ranula or cervical ranula is amucous extravasation cyst of the sublingual gland. It is slightly common in females, shows no side preference, and is more prevalent in the second and third decades of life. It typically manifests as a painless, nonmobile swelling in the neck. The pathogenesis of plunging ranula is the discontinuities of the mylohyoid muscle in a position that would allow extravasation of sublingual gland mucin. The histologic appearance is characteristically of a cyst, devoid of epithelium or endothelium, with a vascular fibro-connective tissue wall containing some chronic inflammatory cells and macrophages stuffed with mucin. The correct diagnosis is essential for the most effective treatment, which is exicision of the sublingual gland. The plunging ranula must be differentiated clinically and histomorphologically from thyroglossal duct cyst, dermoid cyst, branchogenic cyst, lymphangioma, laryngocele, lipoma, hemangioma, cervial thymic cyst, cysts of the parathyroid or thyroid gland, lymphadenopathy, abscess, or tumor. We report a case and review the literatures, in our case, 23-year old man were diagnosis as plunging ranula after have been taken sialogam, MRI, etc. He underwent surgery via a cervical approach. The ranula reached the anterior neck by passing through a dehiscence in the mylohyoid muscle. A pseudocyst was extirpated. Although total sublingual gland excision was not performed, no recurrence was observed during 6 months follow-up periods.

• Clinical and Experimental Pediatrics
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• 제58권4호
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• pp.148-153
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• 2015

The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium resorption in kidney. They can also cause a type 5 Bartter syndrome by inhibiting the apical potassium channel in the thick ascending limb of the loop of Henle in the kidney. This study presents a patient who had autosomal dominant hypocalcemia with Bartter syndrome due to an activating mutation Y829C in the transmembrane domain of the CaSR. Symptoms of hypocalcemia occurred 12 days after birth and medication was started immediately. Medullary nephrocalcinosis and basal ganglia calcification were found at 7 years old and at 17 years old. Three hypercalcemic episodes occurred, one at 14 years old and two at 17 years old. The Bartter syndrome was not severe while the serum calcium concentration was controlled, but during hypercalcemic periods, the symptoms of Bartter syndrome were aggravated.

• Clinical and Experimental Pediatrics
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• 제46권10호
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• pp.1032-1035
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• 2003

저자들은 미숙아에서 이학적 검사상 AHO를 동반하지 않고, 생화학 검사에서는 저칼슘혈증, 고인산혈증, 혈청 PTH의 증가와 24시간 소변의 기저 cAMP의 증가를 보이면서, 대퇴골의 자발골절을 동반했던 가성부갑성선 기능저하증 1례를 문헌 고찰과 함께 보고하는 바이다.