• Annals of dermatology
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• 제30권6호
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• pp.716-720
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• 2018

Perforating granuloma annulare (PGA), a rare variant of granuloma annulare, is characterized by transepidermal elimination of altered collagen that clinically manifests an umbilicated papule with a central crust. It can be confused with papulonecrotic tuberculid (PNT) because of their similar appearance. Unlike PGA, PNT is usually related to tuberculosis infection with a typical histologic finding of wedgeshaped dermal necrosis. Here, we report the first Korean case of PGA mimicking PNT both clinically and histologically. A 43-year-old Korean woman presented with erythematous papules localized on the extensor surface of her limbs for one year. Some of these papules had a central umbilication or a crust. Regarding comorbidity, she had latent tuberculosis diagnosed with $QuantiFERON^{(R)}-TB$ Gold test about five months ago. She was on antituberculous medication. Initially, a diagnosis of papulonecrotic tuberculid accompanied by latent tuberculosis was considered. However, despite taking the antituberculous medication for five months, her skin lesions were not improved. Biopsy specimen from her arm lesion showed wedge-shaped area of necrosis in the dermis. Additionally, there were multiple focal mucin depositions and palisading granulomatous inflammation throughout the dermis. A diagnosis of PGA was made and she was treated with topical corticosteroid. After two weeks of applying topical corticosteroid, most of her skin lesions disappeared, leaving some hyperpigmented scars.

• Tuberculosis and Respiratory Diseases
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• 제62권6호
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• pp.536-539
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• 2007

저자들은 경부 림프절 종대와 사지와 손가락의 홍반성 구진을 주소로 내원한 27세 여자 환자에게서 결핵성 림프절염과 구진괴사성 결핵진을 동시에 진단하고 항 결핵 요법을 통해 치유를 보인 1예를 경험하고, 구진괴사성 결핵진의 정확한 이해와 진단이 결핵 환자의 발견에 도움이 될 것으로 생각되어 문헌 고찰과 함께 보고하는 바이다.