• Title/Summary/Keyword: Pacific

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CV Safety & Future Generation COX-2 inhibitors

  • Shin, Song-Seok;Byun, Young-Joo;Lim, Kyung-Min;Choi, Jin-Kyu;Lee, Ki-Wha;Moh, Joo-Hyun;Kim, Jin-Kwan;Jeong, Yeon-Su;Kim, Ji-Young;Choi, Young-Hoon;Koh, Hyun-Ju;Park, Young-Ho;Oh, Young-Im
    • Proceedings of the PSK Conference
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    • 2005.04a
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    • pp.67-68
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    • 2005
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Zoogeography of Taiwanese Fishes

  • Nakabo, Tetsuji
    • Korean Journal of Ichthyology
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    • v.21 no.4
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    • pp.311-321
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    • 2009
  • Three categories (freshwater, amphidromous, and marine fishes) of Taiwanese fishes are analyzed on the basis of zoogeographic elements, viz. China element, Indo-China element, Indo-West Pacific element, Indo-Pacific element, North-Pacific element, Japan-Oregon element, and circumtropical element. Freshwater fishes, which include the China and Indo-China elements, are distributed on part of the boundary area between the Palaearctic and Oriental regions of Wallace (1876). Diadromous fishes include the North-Pacific, Indo-China and Indo-West Pacific elements. Taiwanese salmon, a landlocked (initially diadromous) species that became established in Taiwan between 0.5 my B.P. and the early Pleistocene, is recognized as a distinct taxon included within the Oncorhynchus masou complex, which comprises here three species and two subspecies, viz. Oncorhynchus masou masou (Sancheoneo, Songeo, Sakura-masu or Yamame), O. masou ishikawae (Satsuki-masu or Amago), O. sp. (Biwa-masu), and O. formosanus (Taiwanese salmon), based on molecular, morphological and biological studies. Marine fishes are discussed under the following headings, brackish-water fishes (fishes of brackish waters and seas adjacent to continental coastlines, North Pacific and Indo-West Pacific elements; fishes of brackish waters and seas primarily around islands, Indo-West Pacific element), reef fishes (fishes of inshore reefs along continental coastlines from 0 to ca.100 m depth, Indo-West Pacific element; fishes of inshore reefs primarily around islands from 0 to ca.100 m depth, Indo-West Pacific element; fishes of offshore reefs along continental shelf edges from ca.150 to 300 m depth, circumtropical and Indo-Pacific elements; fishes of offshore reefs primarily around islands from ca.150 to 300 m depth, Indo-Pacific element), demersal fishes (fishes on continental shelves shallower than ca.150 m depth, Indo-West Pacific and Japan-Oregon elements; fishes on edges and upper continental slopes from ca.150 m to 500 m depth, Indo-West Pacific, Indo-Pacific, and circumtropical elements; fishes on lower continental slopes to abyssal plains from ca.500 m to 6,000 m depth, circumtropical element and rarely Indo-Pacific element), pelagic fishes (epipelagic fishes from 0 to ca.150 m depth, Indo-West Pacific, Indo-Pacific or circumtropical elements; meso- and bathypelagic fishes from ca.150 to 3,000 m depth, circumtropical element). The distribution of Taiwanese marine fishes are influenced by the Kuroshio Current, low-salinity and low-temperature waters from mainland China, and sea-bottom topography.

N-4-Substituted-benzyl-N'-tert-butylbenzyl Thioureas as Vanilloid Receptor Ligands: Investigation on the Role of Methanesulfonamido group in Antagonistic Activity

  • Park, Hyeung-Geun;Choi, Je-Yeon;Choi, Sea-Hoon;Park, Mi-Kyung;Lee, Ji-Hye;Suh, Young-Ger;Cho, Ha-Won;Oh, Uh-Taek;Lee, Ji-Youn;Kang, Sang-Uk;Lee, Jee-Woo;Kim, Hee-Doo;Park, Young-Ho;Jeong, Yeon-Su;Choi, Jin-Kyu;Jew, Sang-Sup
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.173.2-173.2
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    • 2003
  • Vanilloid receptor I (VR1) is a nonselective cation ion channel placed in the plasma membrane of peripheral sensory neurons that is potential target for analgesia A series of N-4-substituted-benzyl-N'-tert-butylbenzyl thioureas were prepared for the study of their agonistic/antagonistic activities to the vanilloid receptor in rat DRG. Their structure-activity relationship in reveals that not only the two oxygens and amide hydrogen of sulfonamido group but also the optimal size of methyl in methanesulfonamido group play an integral role for the antagonistic activity on vanilloid receptor.

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Design. Synthesis and Biological Activities of Novel Vanilloid Receptor (VR) Agonists and Antagonists

  • Suh, Young-Ger;Lee, Bo-Young;Kim, Jin-Kwan;Min, Kyung-Hoon;Park, Ok-Hui;Lee, Young-Sil;Oh, Uh-Taek;Park, Young-Ho;Joo, Yung-Hyup;Choi, Jin-Kyu;Jeong, Yeon-Su;Koh, Hyun-Ju
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.355.1-355.1
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    • 2002
  • Recently. we have reported that several lipoxygenases products directly activate the capsaicin-activated channel as intracellular messengers in neuron. In particular, 12-(S)-hydroperoxyeicosatetraenoic acid turned out to be the most potent endogenous VR activator. This finding prompted us to search for a novel non-vaniloid VR agonists and antagonists. We have designed and synthesized a series of non-vanilloid VR binding ligands based on the structural simllarity between 12-HPETE and capsaicin, the natural VR agonist. Our recent studies on the development of selective vanilloid receptor agonists and antagonists will be presented.

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The U.S. Maritime Strategy Against the Japan in the Pacific War - Geopolitical Perception and The U.S. Response Against the Revisionist Power - (태평양 전쟁기 일본에 대한 미국의 태평양 해양전략 - 지정학적 인식과 도전에 대한 대응을 중심으로 -)

  • Jung, Gwang-Ho
    • Strategy21
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    • s.38
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    • pp.47-82
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    • 2015
  • To control the sphere, it required a strategic understanding to sphere and a power for overcome to it. In the early 20th century, the Pacific-War is a confrontation between the U.S. and the Japan for holding supremacy a pacific ocean sphere, building on maritime geopolitical perception. The Pacific ocean is a large of sphere, so if a country pursues a Pacific region supremacy, it needs a strategic perception and capability to control the sphere. After the U.S. has unified the continental, it has formed geopolitical perception in the Pacific ocean and by the way to control the Pacific ocean selected a naval power. The U.S. must have overcome a Pacific sphere for getting through to the Pacific region, this concept has developed the War Plan Orange(war plan relations with the Japan). Meanwhile, at this point of time, the Japan has recognized to a geopolitical point of view about security environment in the Pacific ocean. like as the U.S. has the War Plan Orange in mind for building on geopolitical perception of the Pacific ocean, the Japan also has learned geopolitical perception from the U.S. Because of this, the Japan has established the Interception-Attrition strategy(war plan relations with the U.S.). If we don't have overcome a sphere of the Pacific ocean, we don't hold hegemony of the Asia-Pacific region. So the analysis of perspective maritime geopolitics about the Pacific war is a meaningful study.