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Review on Clinical Trials of Chemotherapy Induced Toxicity with Acupuncture in PubMed Database (PubMed 검색을 통한 항암화학요법 부작용 관련 침 임상시험 현황 고찰)

  • Kim, Jong Yoon;Kim, Jin Youp;Kim, Nam Sik;Kim, So Jung;Oyungerel, Munkhgerel;Kim, Yong Suk;Choi, Do Young;Nam, Sang Soo
    • Journal of Acupuncture Research
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    • v.30 no.2
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    • pp.43-53
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    • 2013
  • Objectives : The purpose of this study is to review of Clinical trials related to the treatment of chemotherapy induced-toxicity by acupuncture therapy. Methods : We searched PubMed by using word of "chemotherapy induced, acupuncture" (Limits : Full text available, 10 years, Clinical trials, Humans, English). We analyzed 15 research paper and examined published journals, years, countries, topic, study design, their results, interventions, participants and instruments of assessment. Results : Eleven journals with fifteen papers were searched. These papers were published in USA, Germany, etc. On the topic of these clinical trials, seven of them were about nausea(vomiting), two about peripheral neuropathy, two about hot flash, two about arthralgia and one about neutropenia, one about fatigue. Six of these studies were single blinded, randomized controlled trial. Twelve studies reported significant effect. The median for number of final participants was 35.5 persons. Assessment for outcomes were versatile questionnaire, nerve conduction studies, WBC, ANC, G-CSF examination, etc. Conclusions : Their median for impact factor was 3.650 and average modified Jadad score of six RCTs was 4.33. In order to provide appropriate evidence regarding the effectiveness of acupuncture in treatment for chemotherapy-induced toxicity, more rigorous and well-designed studies are necessary.

Systematic Search for Guidelines to Prevent Catheter-associated Urinary Tract Infections-Part II: Using the Ovid MEDLINE (유치도뇨관 감염예방 가이드라인에 관한 체계적 문헌검색 사례-Part II: Ovid MEDLINE 이용)

  • Park, Hyunyoung;Jang, Keum-Seong;Choi, Ja-Yun;Kim, Yun-Hee
    • Journal of Korean Academy of Nursing Administration
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    • v.21 no.1
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    • pp.64-76
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    • 2015
  • Purpose: To implement evidence-based nursing, it is important to know where and how to find the best available evidence. This study was conducted to identify the results of a search from Ovid MEDLINE and to compare the results from Ovid MEDLINE with those from PubMed MEDLINE. Methods: Four different approaches via Ovid MEDLINE were used to search for guidelines on preventing catheter-associated urinary tract infections. Outcomes of this study were the number of records and relevant literature, and the sensitivity and precision of the search methods via Ovid MEDLINE. Results: The number of retrieved items ranged 23 to 6,005 and that of relevant studies, 5 to 8 of 8. Simple searches resulted in the highest sensitivity of 100.0%. When using MeSH terms and limits feature, the precision was highest (21.7%) among four approaches for literature searches. Simple searches in Ovid had higher sensitivity and lower precision than those in PubMed. Conclusion: Simple searches in Ovid may be inefficient for busy clinicians compared to PubMed. However, to ensure a comprehensive and systematic literature search, using Ovid MEDLINE in addition to PubMed is recommended.

The Research Trends on the Acupuncture Treatment of Lumbar Herniated Intervertebral Disc Using PubMed Database (PubMed 검색을 통한 요추 추간판 탈출증의 침치료 연구 동향)

  • Shin, Woo-Suk;Park, Won-Hyung;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.24 no.4
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    • pp.49-60
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    • 2014
  • Objectives The purpose of this study is to research current trends of acupuncture treatment of lumbar herniated intervertebral disc using the PubMed database. Methods We set up the search strategy and investigated clinical trials on acupuncture treatment of lumbar herniated intervertebral disc through PubMed search. This study analyzed previous researched papers published from January 1st, 2000 to April 30th, 2014, and classified them by publication year, journal names, types of literature, treatment methods and evaluation scales. To assess the quality of the reviewed literature, randomized controlled trial (RCT) studies were assessed by Cochrane's risk of bias (ROB) tool and non-RCT studies were assessed by risk of bias for non-randomized studies (RoBANS). Results We found 35 studies on the acupuncture treatment of lumbar herniated intervertebral disc. Papers on this topic have been published, on average, three to four times annually in 9 journals since the mid-2000's. The journal with the largest number of publications was Chinese Acupuncture & Moxibustion, and most of articles were classified as RCT. Acupuncture treatment was performed individually or together with other treatments. The most frequently used pain evaluation index was visual analogue scale (VAS). The index of effective rate was used frequently but there was a lack of objectivity. In regards to the quality of the studies, outcome assessment in RCT showed that random sequence generation, allocation concealment, and the blinding of participants and personnel increase potential of risk of bias. For non-RCT assessment, outcome showed that confounding variable, measurement of intervention were at high risk of bias. Conclusions In order to obtain objective clinical evidence of acupuncture treatment of lumbar herniated intervertebral disc, further clinical studies should be designed to minimize the risk of bias, using STRICTA with larger sample sizes.

Epidemiological Trends of Histopathologically WHO Classified CNS Tumors in Developing Countries: Systematic Review

  • Khan, Ishaq;Bangash, Mohammed;Baeesa, Saleh;Jamal, Awatif;Carracedo, Angel;Alghamdi, Fahad;Qashqari, Hanadi;Abuzenadah, Adel;AlQahtani, Mohammed;Damanhouri, Ghazi;Chaudhary, Adeel;Hussein, Deema
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.205-216
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    • 2015
  • Background: Many developing countries are lagging behind in reporting epidemiological data for individual central nervous system (CNS) tumors. This paper aimed to elicit patterns for the epidemiology of individual World Health Organization (WHO) classified CNS tumors in countries registered by WHO as "developing". Materials and Methods: Cyber search was carried out through 66 cancer networks/registries and 181 PubMed published papers that reported counts of CNS tumors for the period of 2009-2012. The relationship between the natural log of incidence Age Standardized Rate (ASR) reported by Globocan and Latitude/ Longitude was investigated. Results: Registries for 21 countries displayed information related to CNS tumors. In contrast tends for classified CNS tumor cases were identified for 38 countries via 181 PubMed publications. Extracted data showed a majority of unclassified reported cases [PubMed (38 countries, 45.7%), registries (21 countries, 96.1%)]. For classified tumors, astrocytic tumors were the most frequently reported type [PubMed (38 countries, 1,245 cases, 15.7%), registries (21 countries, 627 cases, 1.99%]. A significant linear regression relationship emerged between latitudes and reported cases of CNS tumors. Conclusions: Previously unreported trends of frequencies for individually classified CNS tumors were elucidated and a possible link of CNS tumors occurrence with geographical location emerged.

Asynchronous Sensing Data Aggregation and Processing Mechanism for Internet of Things Environment (사물 인터넷 환경에서 비동기 센싱 데이터 수집 및 처리 메커니즘)

  • Kang, Yunhee;Ko, Wan-Ki
    • KIPS Transactions on Computer and Communication Systems
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    • v.3 no.11
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    • pp.403-408
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    • 2014
  • In the Internet of Things(IoT) era, many of the things or objects that enclose our environments are able to associate with those things on the Internet. To construct IoT systems, it needs to consider a component for acquiring and aggregating of sensory data via things with sensors and instruments, which is connected by diverse networks, in IoT environment. An IoT system is intrinsically distributed in a variety of ways. In addition, to manage an IoT system efficiently, interoperability is needed to meet requirements while the IoT system is designed to deliver data among its applications. In this paper, a reference architecture based on asynchronous messaging is defined and used for designing an IoT system. To apply the architecture, we discuss how to manage data streams with real-time characteristics and make a prototype based on pipe-and-filter to produce and consume them by a pub/sub messaging system NaradaBrokering.

A Study on the Verification of Integrity of Message Structure in Naval Combat Management System

  • Jung, Yong-Gyu
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.12
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    • pp.209-217
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    • 2022
  • Naval CMS(Combat Management System) is linked to various sensors and weapon equipment and use DDS(Data Distribution Service) for efficient data communication between ICU(Interface Control Unit) Node and IPN(Information Processing Node). In order to use DDS, software in the system communicates in an PUB/SUB(Publication/Subscribe) based on DDS topic. If the DDS messages structure in this PUB/SUB method does not match, problems such as incorrect command processing and wrong information delivery occur in sending and receiving application software. To improve this, this paper proposes a DDS message structure integrity verification method. To improve this, this paper proposes a DDS message structure integrity verification method using a hash tree. To verify the applicability of the proposed method to Naval CMS, the message integrity verification rate of the proposed method was measured, and the integrity verification method was applied to CMS and the initialization time of the existing combat management system was compared and the hash tree generation time of the message structures was measured to understand the effect on the operation and development process of CMS. Through this test, It was confirmed that the message structure verification method for system stability proposed in this paper can be applied to the Naval CMS.

Systemic Review: The Study on Bee Venom Related to Cancer in PubMed (암관련 봉독 연구에 대한 고찰-PubMed를 이용한 Medline 검색)

  • Yun, Hyoun-Seok;Lee, Jae-Dong;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.17 no.4
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    • pp.69-78
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    • 2000
  • Objective : To research the trends of the study related to bee venom and cancer, and to establish the hereafter direction of the study on bee venom herbal acupuncture. Method : We searched in PubMed, with bee venom and cancer(in English, with abstract) Results : 1. We searched 28 Journals, 36 Papers. the frequency of Journals and Papers was as follows: Biochem Biophys Res Commun(4 Papers), FEBS Lett(3), Life Sci, Proc Natl Acad Sci USA, J Immunol(each 2), other 23 Journals(each 1). 2. The pattern of the study was as follows: Review article(3 Journals, 3 Papers), Epidemiologic study(1, 1), Experimental study(24, 32) In vivo 1, 1), In vitto(24, 31) 3. The involved components of bee venom were as follows: Melittin(20), Apamin(8), Phospholipase A2(3), Melittin & Phospholipase A2(3), Melittin& Tertiapin(1). 4. The involved cancer was as follows: leukemia(9), tumor(5), neuroblastoma(4), pituitary tumor and pheochromocytoma(each 3), lymphoma, astrocytoma, glioma and lung cancer(small cell carcinoma)(eacn 2), bladder carcinoma, pancreatic cancer, breast carcinoma, ovarian carcinoma and spuamous cell carcinoma(each 1) Conclusion : We concluded that the most frequent pattern of the study was in vitro experimental study with peptide components of bee venom and the most frequeni invovled cancer was leukemia.

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Systemic Review : The Study on Electroacupuncture in PubMed (Pub Med 검색(檢索)을 통한 전침(電鍼)의 최신(最新) 연구(硏究)에 관한 고찰(考察) -임상(臨床) 논문(論文) 중심(中心)으로-)

  • Seo, Dong-Min;Kang, Sung-Keel
    • Journal of Acupuncture Research
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    • v.19 no.3
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    • pp.168-179
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    • 2002
  • Objective : To research the trend of the study related to electroacupuncture and to establish the hereafter direction for the study on electroacupuncture. Methods : We have referred to PubMed, with electroacupuncture (Limits: 5 Years, only items with abstracts, English, Human) Results : 1. We have searched 67 papers in 49 journals on electroacupuncture. 2. The pattern of study was as follows: review articles-8 papers in 8 journals, RCT articles-22 papers in 16 journals, meta-analysis-2 papers in 2 journals, and clinical trials-29 papers in 14 journals. 3. How frequently each Meridians was used for electroacupuncture in the searched papers was as follows: Large Intestine Meridian-14 times, Stomach Meridian-12 times, GallBladder Meridian-5 times, Governor Vessel-4 times, Conception Vessel-3 times, Pericardium Meridian-2 times, Triple Energizer Meridian-2 times, and Liver Meridian-2 times in that order. 4. The acupoints used in the searched papers were as follows: LI4-8 times, ST36, LI11, and GB34-3 times, GV20, LR3, and PC6-2 times in that order. 5. The diseases in the searched papers were as follows: pain, stroke, and others. Conclusion : More clinical data would be needed to prove the effects of electroacupuncture for better application.

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A PubMed Literature Study of Korean Medicine Treatment (Acupuncture) in Irritable Bowel Syndrome (PubMed로 검색한 과민성장증후군의 침치료에 관한 문헌 고찰)

  • Chang, Seok Joo;Kim, Jang Hyun;Min, Sang Yeon
    • The Journal of Pediatrics of Korean Medicine
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    • v.32 no.3
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    • pp.119-130
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    • 2018
  • Objectives The purpose of this study is to review the effectiveness of acupuncture treatment in irritable bowel syndrome (IBS). Methods We reviewed 8 randomized controlled trials (RCT) of acupuncture treatment in IBS which were published from 2008 to 2018 in PubMed. The acupoints, methods of assessment, treatment, results and adverse events were analyzed. Results There were 8 RCT of acupuncture treatment in IBS. The most commonly used acupoints were 天樞 (ST25), and 上巨虛 (ST37). Frequently used assessments in IBS were Bristol scale, visual analogue scale, IBS-symptom severity score, quality of life, and symptom scale. 3 out of 8 studies, the acupuncture treatment group showed significant effectiveness than that of the control group. Conclusions All of the studies have not shown that the acupuncture treatment was effective in relieving IBS symptoms. More clinical studies are needed to prove the effectiveness of the acupuncture treatment in IBS.

Systemic Review : The Study on Missed Abortion (Pub Med 검색을 통한 계류유산의 최신 연구에 대한 고찰)

  • Park, Chan-Soo;Jung, Min-Yung;Sohn, Young-Joo
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.4
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    • pp.160-174
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    • 2007
  • Purpose: The purpose of this study was to investigate about missed abortion pathophysiology, diagnosis, medical treatment and to research the trend of the study related to missed abortion. Methods: We referred a PubMed site by using search word of "missed abortion"(Limits: 3 Year, only items with abstracts, Human). Results: 37 journals with 49 papers were searched. Conclusion: 1. The study of missed abortion pathophysiology was the following. The first was that important pathologies such as molar pregnancy and placental trophoblastic disease can be diagnosed by routine histopathologic analysis of product of conception following first-trimester spontaneous miscarriages. The second was that coelomic fluid leptin concentration in missed abortion is higher than in normal. The third was that adenosine deaminae activity in serum and placenta of patients with anembryonic pregnancies and missed abortions was low. The forth was that Leptotrichia amnionii sp. nov. was the etiopathogenetic factor in missed abortion. 2. Transvaginal ultrasound assessment of irregular vaginal bleeding is effective in diagonosis of missed abortion. 3. There were medical therapy with misoprostol, mifepristone or anti progesterone for missed abortion. Misoprostol was administrated oral(sublingual) and vaginal.

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