• Journal of Ginseng Research
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• 제33권1호
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• pp.48-54
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• 2009

Epileptifrom discharges were induced in the telencephalon of the adult zebrafish via perfusion with pentylenetetrazole (PTZ), bicuculline methiodide, kainic acid-treated artificial cerebrospinal fluid (aCSF), and $Mg^{2+}$-free aCSF. Ginseng total saponin [GTS ($50{\mu}g/ml$)] was shown to attenuate the occurrence rate of epilpetiform discharges by 50-75%, compared to the control. Ginsenoside $Rg_1$ ($130{\mu}M$) reduced the epileptiform discharges in the isolated telencephalon and delayed the occurrence of behavioral seizures observed from the adult zebrafish placed in the PTZ (10 mM)-containing aquarium water. However, Re was not effective in the suppression of epileptiform discharges and behavioral seizures. These results indicate that $Rg_1$ may be useful in the control of epileptiform discharges and effective in controlling behavioral seizures, and that the zebrafish can be used as a model animal for the testing of potential anticonvulsant drugs.

• Journal of Advanced Marine Engineering and Technology
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• 제37권8호
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• pp.918-931
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• 2013

기존의 Pan-Tilt Zooming 카메라를 이용한 객체 추적은 카메라를 통해 획득한 영상을 분석하여 물체의 이동을 검출하였다. 그러나 이 방식은 영상처리를 위한 알고리즘과 이를 위한 하드웨어 비용이 소요되었다. 그리고 주변 환경의 변화나 영상 잡음 등으로 유효하지 않은 영상이 획득되는 경우나 사각지대가 존재하여 영상의 획득 자체가 불가능한 경우에는 대응이 어렵다. 본 논문에서는 영상 정보처리 기반의 객체 추적 기술이 가지는 한계를 극복하기 위해 무선 센서 네트워크 기반의 IEEE 802.15.4 표준을 적용한 GPS수신기가 장착된 센서노드를 시설물에 장착하여 센서노드의 가속도 센서가 장착된 시설물의 움직임을 인식하고 해당 센서노드의 GPS 정보를 이용하여 물체를 추적할 수 있는 시스템을 제안한다. 이 시스템은 영상처리에 요구되는 연산량을 감소시킴과 동시에 넓은 지역의 이동 물체를 추적할 수 있도록 효율적인 PTZ 카메라 제어를 가능하게 한다. 또한 센서노드의 유동적 장착이 가능할 수 있도록 무선의 메쉬 네트워크를 구현하여 설치의 효율성을 올렸다.

• 한국한의학연구원논문집
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• 제3권1호
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• pp.199-213
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• 1997

In convulsion state by PTZ in rat, anticonvulsive effect and some of ${\gamma}-aminobutyric$ acid(GABA)-related mechanisms of Buthus extract in brain was experimented. It was inhibited GABA-T activity, lipid peroxide generation and xanthine oxidase activity as scheduled administration in vitro and vivo. And the content of brain glutathione was increased as scheduled administration in rat. In convulsion state by PTZ of previously managed rat by Buthus extract, onset time and duration were non-specific changes but recovery time and severity was remarkably reduced. In conclusion speculated that Buthus extract inhibits convulsion by control of GABA content In brain.

• 동의생리병리학회지
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• 제16권3호
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• pp.567-571
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• 2002

In order to prove the sedative, anticonvulsive effects of Incenses and to identify the effect of this medicine to cerebral glutamic acid and GABA density in experimental animal. we used Incense which was made of traditional herb medicines. We also examined what kind of material is to be involved in biosynthesis of these elements. In addition we experimented to find out synthesis of active GABA-T. Incenses were inhaled 8 hours a day for 4 weeks to mice. Finally we have following results. On the convulsion induced by pentylenetetrazole(PTZ), Incenses showed significant anticonvulsive effect. Density of glutamic acid in brain was significantly decreased. On the contrary, density of GABA was significantly increased. The Activity of GABA- T in brain was significantly reduced. The quantity of lipid peroxide in the brain was significantly decreased. Activity of xanthine oxidase and aldehyde oxidase were significantly reduced in brain. From the above results, we confirmed that Incenses decreased the density of glutamic acid, increased GABA density and decreased the activity of GABA- T in brain. For the convulsion which was induced by PTZ, Incenses showed significant anticonvulsive effect. With this we can recognize that Incenses had ability to control the quantity of lipid peroxide in brain. In the conclusion, Incenses has significant anticonvulsive effect, so I strongly recommend to prescribe Incenses to treat convulsive disorder like epilepsy.

• Biomolecules & Therapeutics
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• 제3권3호
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• pp.199-204
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• 1995

Gastrodia elata is a medicinal plant which has been used as anticonvulsant in Korea, Japan and China. This study was conducted to examine the action mechanism of Gastrodia elata centering around the change of GABA and glutamic acid level in brain while observing the anticonvulsive effect in PTZ-induced seizure model. Seizures were reduced effectively by pretreatment of ether soluble part of methanol extract of Gastrodia elata. The pretreatment of ether soluble part inhibited not only the decrease of brain GABA level but also the increase of brain glutamic acid level observed in PTZ model of convulsive dose. Although there was not any change in glutamic acid level, the same development was also observed in the model of subconvulsive dose. From above results, it seems that the anticonvulsive component of Gastrodia elata is lipophilic, and its action mechanism is originated from both control action of GABA level and inhibition of glutaminergic neurotransmission.

• 전기전자학회논문지
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• 제22권2호
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• pp.281-288
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• 2018

본 논문에서는 쿠다(CUDA)를 사용하여 GPU 리소스를 분배하는 지능형 얼굴 인식 및 트래킹 시스템을 제안한다. 제안한 시스템은 GPU 리소스를 최적의 상태로 분배하는 GPU 할당 알고리즘, 딥러닝을 이용한 얼굴 영역 검출, 딥러닝을 이용한 얼굴 인식, 실시간 얼굴 트래킹, PTZ 카메라 제어 등의 5단계로 구성되어진다. 멀티 GPU 리소스를 최적의 상태로 분배하는 GPU 할당 알고리즘은 고정적으로 스레드에 GPU를 할당하는 방식과 달리 GPU의 활성화 정도에 따라 유동적으로 GPU 리소스를 분배한다. 따라서 안정적이고 효율적인 멀티 GPU 사용을 가능하게 하는 특징이 있다. 제안된 시스템에 대한 성능을 평가하기 위하여 리소스 분배를 하지 않은 시스템과 제안한 시스템을 비교한 결과, 리소스를 분배하지 않은 시스템은 불안정한 동작을 보이는 반면에 제안한 시스템에서는 안정적으로 구동됨으로서 효율적인 리소스 사용을 보였다. 따라서 제안된 시스템의 효용성이 입증되었다.

• 제어로봇시스템학회논문지
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• 제19권1호
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• pp.65-71
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• 2013

In this work, new smart phone based moving target detection is proposed. In order to implement the task, methods of real time image transmission from network camera, motion detecting algorithm and its effective implementation are also addressed. The network camera transfers image data by MJPEG format which contains various information such as data and IP address, and the smart phone separates the image data received through a WiFi module. Later, the image data is converted to a Bitmap image format, and with the help of the embedded OpenCV library on a smart phone and algorithm, it was found that the moving object was identified effectively in terms of real time monitoring and detection.

• 한국지능시스템학회논문지
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• 제20권4호
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• pp.580-585
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• 2010

본 논문은 SOPC 기반 NIOS II 임베디드 프로세서와 C2H를 이용하여 무인 자동 객체 추적 시스템을 구현하였다. 단일PTZ 카메라를 이용한 디지털/아날로그 신호의 입출력, 이미지 프로세싱, 시리얼 통신 그리고 네트워크 통신의 제어를 C2H에 의한 IP 구성과 SOPC 기반 NIOS II 임베디드 프로세서에서 각각의 IP를 효과적으로 제어함으로써 다양한 모니터링 정보를 네트워크로 제공할 수 있는 시스템을 설계, 구현 하였다. SOPC 기반 NIOS II 임베디드 프로세서의 유연성과 고급 알고리듬의 복잡성을 소프트웨어 프로그래밍 언어의 C와 하드웨어 프로그래밍 언어로 유동적으로 컴파일하여 IP화 할 수 있는 특성을 적용함으로서 실시간적으로 무인 객체 추적할 수 있는 시스템의 성능을 향상 시킬 수 있었다.

• 대한약침학회지
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• 제21권4호
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• pp.277-283
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• 2018

Objectives: Ethanol withdrawal following its chronic use is a serious outcome and challenging to treatment. The chronic use of ethanol induces a progressive neuroplasticity in different reigns of brain. In this study we evaluated the effects of aqueous extract of Crocus sativus L. (saffron) and its active compound, crocin, on the withdrawal behavior induced after repeated administration of ethanol, in two regimens of prophylactic (administration of drugs concomitant with the induction of dependence) and treatment (administration of drugs during the period of ethanol withdrawal) in mice which received ethanol. Methods: Ethanol dependence was induced by oral administration of 10% v/v ethanol (2 g/kg) for 7 days. The aqueous extracts of saffron (40, 80 and 160) and crocin (10, 20 and 40 mg/kg) were administered to mice in two regimens of prophylactic (along with ethanol) and treatment (during withdrawal period). Diazepam (1 mg/kg) was used as a positive control. Six hours after discontinuation of the ethanol, seizure was evaluated by the sub-convulsive dose of pentyleneltetrazole (PTZ) (30 mg/kg). The open field test and Rota rod test were used for evaluation of locomotor activity and motor incoordination, respectively. Results: Both extracts and crocin increased the number of crossed lined in the open field test. PTZ kindling seizure was inhibited in animals received extract (80 and 160 mg/kg) in both regimens. Motor incoordination was only improved following administration of crocin. Conclusion: The aqueous extract of saffron and crocin can be considered as safe agents and reliable alternative to diazepam in management of ethanol withdrawal syndrome.

• 전기전자학회논문지
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• 제17권2호
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• pp.104-110
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• 2013

본 논문에서는 다양한 CCTV 카메라를 지원하는 스마트 케어 관제 시스템을 소개한다. 위급 상황 발생 시 신고자의 상황을 실시간으로 관찰하기 위하여 서버에서는 신고자의 위치 좌표를 기반으로 CCTV 카메라의 팬, 틸트, 줌 제어를 자동으로 수행한다. 또한 신고자를 찾아 촬영하며 영상처리 및 갱신되는 위치 정보를 이용하여 신고자를 추적한다. 다양한 CCTV 카메라를 지원하기 위하여 Genetec 개발 툴을 이용하여 관제 시스템을 구현한다. 스마트 케어 관제 시스템을 이용하여 신고자의 위급 상황에 대하여 구조자는 신고자의 CCTV 영상을 빠르게 제어하고 감시할 수 있기 때문에 구조 작업의 효율이 개선될 수 있다.