• Title/Summary/Keyword: PSSG

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A Clinical Study for the effects of Muscle Energy Techniques on patients with Whiplash Injury caused by Traffic Accidents (교통사고로 유발된 편타성 손상에 대한 근에너지기법(MET)의 임상 연구)

  • Shin, Hyun-Jin;Yoon, Il-Ji
    • Journal of Haehwa Medicine
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    • v.20 no.2
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    • pp.133-140
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    • 2012
  • Objective: The purpose of this study is to figure out the effects of Muscle energy techniques on patients with Whiplash injury caused by traffic accidents Methods: This study was carried out on the 8 patients with cervical pain caused by whiplash injury. These patients was treated with muscle energy techniques addition to acupuncture treatment, physical therapy and herbal medication. The result of this treatment were evaluated by VAS, PAS and PSSG score. Results: The cervical pain of patients was significantly decreased in VAS, PAS and PSSG score. Conclusion: According to the results of this study, it was suggested that MET treatment was effective in reducing cervical pain caused by whiplash injury.

Reductive Depolymerization of Bovine Thyroglobulin Multimers via Enzymatic Reduction of Protein Disulfide and Glutathiony­lated Mixed Disulfide Linkages

  • Liu Xi-Wen;Sok Dai-Eun
    • Archives of Pharmacal Research
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    • v.28 no.9
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    • pp.1065-1072
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    • 2005
  • The nascent thyroglobulin (Tg) multimer molecule, which is generated during the initial fate of Tg in ER, undergoes the rapid reductive depolymerization. In an attempt to determine the depolymerization process, various types of Tg multimers, which were generated from deoxy­cholate-treated/reduced Tg, partially unfolded Tg or partially unfolded/reduced Tg, were subjected to various GSH (reduced glutathione) reducing systems using protein disulfide isomerase (PDI), glutathione reductase (GR), glutaredoxin or thioredoxin reductase. The Tg multimers generated from deoxycholate-treated/reduced Tg were depolymerized readily by the PDI/GSH system, which is consistent with the reductase activity of PDI. The PDI/GSH-induced depolymerization of the Tg multimers, which were generated from either partially unfolded Tg or partially unfolded/reduced Tg, required the simultaneous inclusion of glutathione reductase, which is capable of reducing glutathionylated mixed disulfide (PSSG). This suggests that PSSG was generated during the Tg multimerization stage or its depolymerization stage. In particular, the thioredoxin/thioredoxin reductase system or glutaredoxin system was also effective in depolymerizing the Tg multimers generated from the unfolded Tg. Overall, under the net GSH condition, the depolymerization of Tg multimers might be mediated by PDI, which is assisted by other reductive enzymes, and the mechanism for depolymerizing the Tg multimers differs according to the type of Tg multimer containing different degrees and types of disulfide linkages.

Lateral Epicondylitis of the Elbow by Oriental Medical Treatments : 4 Cases Report (한방치료로 호전된 주관절 외상과염 환자 4례 보고)

  • Uhm, Bong-Kun;Kim, Jeong-Won;Kim, Choo-Young;Han, Sang-Wook;Yang, Kee-Young;Cho, Tae-Young
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.7 no.1
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    • pp.103-112
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    • 2012
  • Objectives : This study was performed to report the effect of oriental medical treatments on the 4 patients with lateral epicondylitis of the elbow. Methods : The 4 patients were treated by Bee Venom acupuncture, Dong-Qi acupuncture, acupuncture on tender points of the origin of the extensor carpi radialis and taping on the extensor carpi radialis. The state of patients was measured by visual analog scale(VAS), elbow range of motion(ROM) and patient's subjective symptom grade(PSSG). Results : After mean 9.5 times of treatments, the recovery of elbow ROM was measured and significant pain relief was seen as the average of VAS changed from 10 to 1.25 and average of PSSG changed from 2.75 to 0.5 grade. Conclusions : These results suggest that oriental medical treatments including Bee Venom acupuncture, Dong-Qi acupuncture, acupuncture, taping are effective to improve the lateral epicondylitis of the elbow.

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