• Computers and Concrete
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• v.32 no.2
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• pp.165-172
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• 2023

The vibration analysis of armchair, zigzag and chiral double-walled carbon nanotubes has been developed by inserting the nonlocal theory of elasticity into thin shell theory. First Donnell shell theory is employed while exercising wave propagation approach. Scale effects are realized by using different values of nonlocal parameters under certain boundary conditions. The natural frequencies have been investigated and displayed for various non-local parameters. It is noticed that on increasing nonlocal parameter, the frequency curve tends to decrease. The frequency estimates of clamped-free boundary condition are less than those of clamped-clamped and simply supported computations. The frequency comparisons are presented for armchair, zigzag and chiral nanotubes. The software MATLAB is used to extract the frequencies of double walled carbon nanotubes.

• Kyungpook Mathematical Journal
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• v.64 no.2
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• pp.353-369
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• 2024

In this study, we investigate the unknown time-dependent heat source function in inverse problems. We consider three general nonlocal conditions; two classical boundary conditions and one nonlocal over-determination, condition, these genereate six different cases. The finite integration method (FIM), based on numerical integration, has been adapted to solve PDEs, and we use it to discretize the spatial domain; we use backward differences for the time variable. Since the inverse problem is ill-posed with instability, we apply regularization to reduce the instability. We use the first-order Tikhonov's regularization together with the minimization process to solve the inverse source problem. Test examples in all six cases are presented in order to illustrate the accuracy and stability of the numerical solutions.

• Smart Structures and Systems
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• v.26 no.1
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• pp.103-115
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• 2020

The cold-formed steel storage racks are extensively employed in various industries applications such as storing products in reliable places and storehouses before distribution to the market. Racking systems lose their stability under lateral loads, such as seismic actions due to the slenderness of elements and low ductility. This justifies a need for more investigation on methods to improve their behavior and increase their capacity to survive medium to severe loads. A standardized connection could be obtained through investigation on the moment resistance, value of original rotational stiffness, ductility, and failure mode of the connection. A total of six monotonic tests were carried out to determine the behavior of the connection of straight 2.0 mm, and 2.6 mm thickness connects to 5 lug end connectors. Then, the obtained results are benched mark as the original data. Furthermore, an extreme learning machine (ELM) technique has been employed to verify and predict both moment and rotation results. Out of 4 connections, increase the ultimate moment resistance of connection by 13% and 18% for 2.0 mm and 2.6 mm upright connection, respectively.

• Smart Structures and Systems
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• v.26 no.2
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• pp.147-156
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• 2020

This numerical study demonstrates the porosity conditions and the intensity of the interactions with the aggressive agents. It is established that the density as well as the elastic modulus are correlated to ultrasonic velocity The following investigation assessed the effects of cement grade and porosity on tensile strength, flexural and compressive of Ultra High Performance Concrete (UHPC) as a numerical model in PLAXIS 2d Software. Initially, the existing strength-porosity equations were investigated. Furthermore, comparisons of the proposed equations with the existing models suggested the high accuracy of the proposed equations in predicting, cement grade concrete strength. The outcome obtained showed a ductile failure when un-corroded reinforced concrete demonstrates several bending-induced cracks transfer to the steel reinforcement. Moreover, the outcome also showed a brittle failure when wider but fewer transverse cracks occurred under bending loads. Sustained loading as well as initial pre-cracked condition during the corrosion development have shown to have significant impact on the corrosion behavior of concrete properties. Moreover, greater porosity was generally associated with lower compressive, flexural, and tensile strength. Higher cement grade, on the other hand, resulted in lower reduction in concrete strength. This finding highlighted the critical role of cement strength grade in determining the mechanical properties of concrete.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.511-517
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• 2016

Scabraside D, a sulfated triterpene glycoside extract from sea cucumber Holothulia scabra, shows various biological activities, but effects on human cholangiocarcinoma cells have not previously been reported. In the present study, we investigated the activity of scabraside D against human cholangiocarcinoma (HuCCA) both in vitro and for tumor growth inhibition in vivo using a xenograft model in nude mice. Scabraside D ($12.5-100{\mu}g/mL$) significantly decreased the viability and the migration of the HuCCA cells in a dose-dependent manner, with 50% inhibitory concentration (IC50) of $12.8{\pm}0.05{\mu}g/mL$ at 24 h. It induced signs of apoptotic cells, including shrinkage, pyknosis and karyorrhetic nuclei and DNA fragmentation on agarose gel electrophoresis. Moreover, by quantitative real-time PCR, scabraside D effectively decreased Bcl-2 while increasing Bax and Caspase-3 gene expression levels suggesting that the scabraside D could induce apoptosis in HuCCA cells. In vivo study demonstrated that scabraside D (1 mg/kg/day, i.p. for 21 days) significantly reduced growth of the HuCCA xenografts without adverse effects on the nude mice. Conclusively, scabraside D induced apoptosis in HuCCA cells and reduced the growth of HuCCA xenographs model. Therefore, scabraside D may have potential as a new therapeutic agent for cholangiocarcinoma.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.583-587
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• 2013

This study aimed to investigate tumor microvessel density (MVD) and lymphatic vessel density (LVD) using the Chalkley method as predictive markers for the risk of axillary lymph node metastasis and their relationship to other clinicopathological parameters in primary breast cancer cases. Forty two node-positive and eighty node-negative breast cancers were immunostained for CD34 and D2-40. MVD and LVD were counted by the Chalkley method at x400 magnification. There was a positive significant correlation of the MVD with the tumor size, coexisting ductal carcinoma in situ (DCIS) and lymph node metastases (P<0.05). In multivariate analysis, the MVD (2.86-4: OR 5.87 95%CI 1.05-32; >4: OR 20.03 95%CI 3.47-115.55), lymphovascular invasion (OR 3.46, 95% CI 1.13-10.58), and associated DCIS (OR 3.1, 95%CI 1.04-9.23) independently predicted axillary lymph node metastasis. There was no significant relationship between LVD and axillary lymph node metastasis. However, D2-40 was a good lymphatic vessel marker to enhance the detection of lymphatic invasion compared to H and E staining. In conclusion, MVD by the Chalkley method, lymphovascular invasion and associated DCIS can be additional predictive factors for axillary lymph node metastases in breast cancer. No relationship was identified between LVD and clinicopathological variables, including axillary lymph node metastasis.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.39 no.spc1
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• pp.151-164
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• 2006

We monitored the current macrozoobenthic community structure after the Sea Prince oil spill around Keumo-do and Sori-do, Korea. Macrobenthic animals were collected seasonally around Sori-Keumo do using a van Veen grab ($0.1m^2$) from October 1999 to April 2000. In total, 196 species were identified at 46 sites around Keumho-do. The mean density was 1,460 individuals/$m^2$, and polychaetes comprised 80% of the total density of the macrozoobenthic. Dominant species were the polychaete Tharyx sp. (51%), the echinoderm Amphioplus megapomus (5%) and the polychaete Lumbrineris longifolia (3%). We identified 176 macrobenthic species at 36 sites around Sori-do. The mean density was 1,068 individuals/$m^2$, and polychaetes was the most abundant faunal group, comprising 41%, followed by mollusks (24%) and echinoderms (20%). Dominant species in Sori-do were the mollusk Potamocorbula amurensis (23%), the chinoderm Amphioplus megapomus (14%), and the polychaete Tharyx sp. (10%). The overall community structures in the study area showed few seasonal changes, although there was a gradual change in the species composition within each benthic community. Tharyx sp. was the most abundant species in the study area. Because this species has not been found in the other coastal areas except during recent investigations, it is considered to have increased during the course of community succession after the oil spill. The macrozoobenthic around Keumo-do showed little change in species richness, whereas around Sori-do, it showed a few increases in species richness after the summer of 1998. The overall density showed the same trend as species richness. Based on improved community indices, we suggest that the macrozoobenthic communities around Sori-Keumo Islands are gradually recovering from the oil-spill damagecaused by the oil spill.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.15 no.6
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• pp.147-154
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• 2015

Recently agile development process became increasing effectiveness, quality, attention to experts in customer satisfaction, as evidenced in this methodology when selecting projects promoting productive efficiency. With regard to contemporary needs and user requirements on the methodology selected to meet this paper is the product based Cross functional team suggested methodology Feature Team model to solve problems of this model, and organizing the Cross functional team, this team but this outcome (product) basis, were examined for the model that points to progress the development across multiple product as a functional unit, value-driven agile project through the Skills-based model and proposed a difference. And it examined the Agile Maturity metrics. PRINCE2 Agile Health-check entries future development direction of Agile techniques is a requirement of the project outset has studied the subject objective evaluation by the assumption that they can be changed at any time, not fixed this way and for the project team through research The proposed.

• The Journal of Asian Finance, Economics and Business
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• v.10 no.2
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• pp.301-311
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• 2023

This research aims to identify the role that small and medium enterprises (SMEs) can play in achieving the economic goals of the vision of Saudi Arabia 2030. The study relied on descriptive analysis, designing a standard model, and analyzing it using the Eviews9 program. The study also adopted the questionnaire as a tool for data collection. The study area covered Alkharj and Hawtat Bani Tamim governorates. The sample size of the study was 142 participants. The study's results confirmed the existence of a significant impact of changes in independent variables (X1, X2, X3, X4), which are (GDP, non-oil exports, number of employees, and public revenues), respectively. The dependent variable (Y) represents the number of small and medium-sized businesses in the Kingdom of Saudi Arabia. Additionally, it was found that 61.3% of small and medium-sized enterprises in the governorates of Al-Kharj and Hawtat Bani Tamim operate in the commercial sector. Most study participants concur that SMEs significantly lowered the unemployment rate and helped boost the GDP rate in the Kingdom of Saudi Arabia. The obstacles and difficulties facing the establishment of these enterprises were financial problems, marketing problems, and corporate monopoly. Furthermore, most of the small and medium l enterprises faced financing problems.

• Journal of Advanced Marine Engineering and Technology
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• v.28 no.2
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• pp.376-381
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• 2004

A rig was constructed to test the performance characteristics and compare the hydraulic forces exerted on a centrifugal type artificial heart impeller. A conventional shaft. seal and bearing system. while driven by a small electric motor. supported the impeller which was separated from the pump casing by a six degree of freedom force transducer (JR3 Ine). Radial (x. y) and axial (z) hydraulic forces were recorded and compared. At physiological operating conditions. the results indicate that the double entry/exit centrifugal pump encounters a smaller radial force and significantly reduced axial thrust. These experimental results are valuable in the design of a magnetic bearing system to suspend the impeller of a centrifugal artificial heart pump. This experimental technique may also be applied to evaluate the required capacity and predict the lifetime of contact bearings in marine pumps.