• Animal cells and systems
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• v.1 no.2
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• pp.363-370
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• 1997

RNase MRP is a ribonucleoprotein complex with a site-specific endonuclease activity. Its original substrate for cleavage is the small mitochondrial RNA near the mitochondrial DNA replication origin, thus it was proposed to generate the primer for mtDNA replication. Recently, it has been shown to have another substrate in the nucleus, such as pre-S.8S ribosomal RNA in nucleolus. The gene for the RNA component of RNase MRP (MRP RNA) was found to be encoded by the nucleus genome, suggesting an interesting intracellular trafficking of MRP RNA to both mitochondria and nucleolus after transcription in nucleus. In this study, genomic DNA encoding MRP RNA was microinjected into the nucleus of Xenopus oocytes, to analyze promoter regions involved in the transcription. It showed that the proximal sequence element and TATA box are important for basal level transcription; octamer motif and Sp1 binding sites are for elevated level transcription. Most of Xenopus MRP RNA was exported out to the cytoplasm following transcription in the nucleus. Utilizing various hybrid constructs, export of MRP RNA was found to be regulated by the promoter and the 5' half of the coding region of the gene. Interestingly, the transcription in nucleus seems to be coupled to the export of MRP RNA to cytoplasm. Intracellular transport of injected MRP RNA can be easily visualized by whole-mount in situ hybridization following microinjection; it also shows possible intra-nuclear sites for transcription and export of MRP RNA.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2010.11a
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• pp.175-177
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• 2010

본 논문에서는 MPEG 의 3차원 비디오 시스템의 표준 깊이정보 맵에 대한 효율적인 부호화를 위하여 전처리 방법을 제안한다. 현재 3차원 비디오 부호화(3DVC)에 대한 표준화가 진행 중에 있지만 아직 깊이정보 맵의 부호화 방법에 대한 표준이 확정되지 않은 상태이다. 제안하는 기법에서는 우선, 입력된 깊이정보 맵에 대하여 원래의 히스토그램 분포를 가우시안 혼합모델(GMM)기반의 EM 군집화 기법에 의한 방법으로 분리 후, 분리된 히스토그램을 기반으로 깊이정보 맵을 여러 개의 영상으로 분리한다. 그 후 분리된 각각의 영상을 배경과 객체에 따라 다른 조건의 mean shift filter로 필터링한다. 결과적으로 영상내의 각 영역 경계는 최대한 살리면서 영역내의 화소 값에 대해서는 평균 연산을 취하여 부호화시 효율을 극대화 하고자 하였다. 실험조건은 $1024{\times}768$ 영상에 대해서 50 프레임으로 H.264/AVC base 프로파일로 부호화를 진행하였다. 최종 실험결과 bit rate는 대략 23% ~ 26% 정도 감소하고 부호화 시간도 다소 줄어드는 것을 확인 할 수 있었다.

• Journal of Electrical Engineering and Technology
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• v.11 no.2
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• pp.519-528
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• 2016

In order to achieve fast computational speed with good visual quality of output video, we propose a frequency domain based new fractal video compression scheme. Normalized cross correlation is used to find the structural self similar domain block for the input range block. To increase the searching speed, cross correlation is implemented in the frequency domain using FFT with one computational operation for all the domain blocks instead of individual block wise calculations. The encoding time is further minimized by applying rotation and reflection DFT properties to the IFFT of zero padded range blocks. The energy of overlap small size domain blocks is pre-computed for the entire reference frame and retaining the energies of the overlapped search window portion of previous adjacent block. Quadtree decompositions are obtained by using domain block motion compensated prediction error as a threshold to control the further partitions of the block. It provides a better level of adaption to the scene contents than fixed block size approach. The result shows that, on average, the proposed method can raise the encoding speed by 48.8 % and 90 % higher than NHEXS and CPM/NCIM algorithms respectively. The compression ratio and PSNR of the proposed method is increased by 15.41 and 0.89 dB higher than that of NHEXS on average. For low bit rate videos, the proposed algorithm achieve the high compression ratio above 120 with more than 31 dB PSNR.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.4
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• pp.70-76
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• 2009

In this paper, we propose the design criteria of the pre-processing scheme used in ABAB type quasi-orthogonal space-time block code(QOSTBC) and derive. The proposed design criteria show how to obtain full-diversity and full-rate (FDFR) property, single-symbol decodability, and increased coding gam. We design an improved ABAB type QOSTBC using the proposed design criteria. The desinged QOSTBC has a superior performance to Dalton's QOSTBC and inherits the merits of Dalton's QOSTBC, which are FDFR property, and single symbol decodability for PAM signal constellation.

• Biomolecules & Therapeutics
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• v.18 no.1
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• pp.1-15
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• 2010

Progress in the development of DNA vaccines and their delivery strategies has been made since their initial concept as a next generation vaccine. Since DNA vaccine includes non-infectious DNA parts of pathogens, it can't cause disease yet it closely mimic the natural process of infection and immune responses. Despite their early promising results of controlling infectious diseases and cancer in small animal models, DNA vaccines failed to display a level of immunogenicity required for combating these diseases in humans, possibly due to their lower protein expression levels. However, increasing evidence has shown that DNA vaccines are clinically well-tolerated and safe. Furthermore, one notable advantage of DNA vaccines includes convenient utilities of plasmid DNAs coding for antigens. For instance, any emerging pathogens could be prevented easily and timely by allowing the simple exchange of antigen-encoding genes. In this review, newly developed DNA vaccine strategies, including electroporation, which has emerged as a potent method for DNA delivery, targeting infectious diseases and cancer will be discussed with a focus on any on-going DNA vaccine trials or progress made pre-clinically and in clinics.

• Korean Journal of Human Ecology
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• v.18 no.2
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• pp.325-340
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• 2009

The study aims at verifying the parents' and children's changing process while using parents' play therapy in parent education program to improve the relationship between parents and their children. The experimental group consisted of 42 mothers who have preschoolers in the age range of 3-5, and was compared with the control group of 42 mothers. They joined together a series of 8 sessions (2 hours? or 16 hours?) once a week and took pre- and post-test. All of the sessions were recorded with a VCR camera. All the changing process the mothers showed was analyzed qualitatively to see what happened to the mothers and their children by the methods of coding, taxonomic analysis, critical events, componential analysis, and casual chain analysis suggested by Spradley(1980). The analyses showed that the mothers who participated in the program come to take more sympathetic, receptive attitudes to their children, while the children get better in the children's emotional behavioral problems in the qualitative analysis as well as the quantitative analysis.

• Journal of KIISE:Software and Applications
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• v.32 no.10
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• pp.956-962
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• 2005

To improve video quality and coding efficiency, H.264/AVC adopts different half pixel calculating method compared with the previous standards. So, the transcoder requires additional works to transcode the pre-coded video contents with the previous standards to H.264/AVC in DCT domain. In this paper, we propose the first half-pixel correction method for MPEG-2 to H.264 transcoding in DCT domain. In the proposed method, MPEG-2 block is added to the correction block obtained by difference calculation of half-pixel values between two standards using DCT reference frame. Experimental results show that the proposed achieves better quality than pixel based cascaded transcoding method.

• Journal of Korea Society of Digital Industry and Information Management
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• v.8 no.4
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• pp.99-105
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• 2012

Recently, there are many user selection algorithms in multi user multiple-input multiple-output (MU-MIMO) systems. One of well-known user selection methods is Semi orthogonal user selection (SUS). It is an algorithm maximizing channel capacity. However, it is applicable only when user's antenna is one. We propose a generalized user selection algorithm regardless of the number of user's antennas. In the proposed scheme, Base station (Bs) selects the first user who has the highest determinant of channel and generates a user group that correlation with first user's channel is less than allowance of correlation. Then, each determinant of channels made up of first user's channel and a user's channel in the generated group is calculated and BS selects the next user who has the highest determinant of that. BS selects following users by repeating above procedure. In this paper, we get better performance because of selecting users who have the highest determinant of channel as well as allowance of correlation optimally calculated through matrix operations.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.4
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• pp.646-652
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• 2015

In this paper, the system-level performance is evaluated for the feedback scheme on the pre-coding matrix index (PMI) and channel quality indication (CQI), which are required for user selection in the multi-user MIMO system. Our analysis demonstrates that the number of users, the number of selected users, and codebook size are the key factors that govern the performance of the best companion grouping (BCG)-based user scheduling. Accordingly, we have confirmed that the probability of forming the co-scheduled user group is determined by these factors, which implies that the number of PMI's and codebook size can be dynamically determined so as to maximize the average system throughput as the number of users varies in the cell.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.12
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• pp.28-33
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• 2007

We present a space-time trellis coded OFDM system in flow fading channels. Generalized principal ratio combining (GPRC) is also analyzed theoretically in frequency domain. The analysis show that the decoding metric of GPRC include the metrics of maximum likelihood (ML) and PRC. The computer simulations with M-PSK modulation are obtained in frequency flat and frequency selective lading channels. The decoding complexity and simulation running times are also evaluated among the decoding schemes.