• The Korean Journal of Zoology
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• v.35 no.4
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• pp.509-517
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• 1992

LiCl (0.047 M)은 Goldhamster의 활동주기 (T)를 평균 1.6시간 연장시키고, 동물 중 20%엑서 단축되는 것으로도 관찰되었다. 1시간 통안의 빛자극(75 Lux)에 의해 주기현상 시점 변화가 나타나는 데 LICI에 의해서 0.3 h 더욱 delav되었고 advance 현상은 1.5 h 감소되었으며 delay엔h advance 전환시기는 1시간 늦게 나타났다. 반면에 7 Lux의 빛 자극에서는 delay가 2.4시간으로 더 증가되었으며 advance 현상은 2.6시간으로 저하되었고, 30분 늦게 delay에서 advance로 전환되었다. subjective day 동안에는 빛자극에 의한 LiCl 효과가 전혀 보이지 않았다. Phase-Response-Curve(PRC)는 Circadian Time에서 delay-advance로 전환되는 mid-subjective night에 점진적으로 변화되는 weak phase curve로 형성되었다. 이 PRC에서 Li이 빛에 대한 민감성을 둔화시키는 효과를 볼 수 있다.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.2
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• pp.281-291
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• 2002

This paper describes the minimum cost design of prestressed reinforced concrete (PRC) hem with rectangular section. The cost of construction as objective function which includes the costs of concrete, prestressing steel, non prestressing steel, and formwork is minimized. The design constraints include limits on the minimum deflection, flexural and shear strengths, in addition to ductility requirements, and upper-Lower bounds on design variables as stipulated by the specification. The optimization is carried out using the methods based on discretized continuum-type optimality criteria(DCOC). Based on Kuhn-Tucker necessary conditions, the optimality criteria are explicitly derived in terms of the design variables - effective depth, eccentricity of prestressing steel and non prestressing steel ratio. The prestressing profile is prescribed by parabolic functions. In this paper the effective depth is considered to be freely-varying and one uniform for the entire multispan beam respectively. Also the maximum eccentricity of prestressing force is considered in every span. In order to show the applicability and efficiency of the derived algorithm, several numerical examples of PRC continuous beams are solved.

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.05a
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• pp.52.2-52.2
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• 2011

Flat form technology for constructing anticancer loaded multi-walled carbon nanotubes (mwCNTs) was introduced in this study. Conventional anticancer drugs, such as MTX (Methotrexate), cisplatin, DOX (Doxorubicin hydrochloride), DAU (Daunorubicin) and EPI (epirubicin) were bio-conjugated with folic acid (FA) for selective targeting tumor cells. Loading efficiencies of the used anticancer drugs on mwCNTs have shown different order of bindings depending on the molecular bind affinity of NH (amine) formation on mwCNTs. MTT assays have shown increased selective target efficiency of FA conjugated mwCNTs on breast cancer cell growth inhibition. All results collectively indicated promising application of mwCNTs as a smart inorganic nanomaterial for selective targeting drug delivery vehicle at tumor tissues.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.1255-1257
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• 2003

This study proposes a single-channel satellite remote sensing algorithm for retrieving aerosol optical thickness over global ocean using FY-1C/1D data. An efficient lookup table (LUT)method is adopted in this algorithm to generate apparent reflectance in channel 1 and channel 2 of FY-1C/1D over ocean. The algorithm scale the apparent reflectance in cloud-free conditions to aerosol optical thickness using a state-of-art radiative transfer model 6S with input of the relative spectral response of channel 1 and 2 of FY-1C/1D. Monthly mean composite maps of the aerosol optical thickness have been obtained from FY-1C/1D global area coverage data between 2001 and 2003. Aerosol optical thickness maps can show the major aerosol source which are located off the west coast of northern and southern Africa, Arabian Sea and India Ocean. These result is very similar to other satellite sensors such as AVHRR and MODIS in the location area of heavy aerosol optical thickness over global ocean. The algorithm have been used to FY-1D operational performance and it is the first operational aerosol remote sensing product in China.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.2
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• pp.179-186
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• 2011

Purpose: This study aimed to compare and assess changes of visual functions in viewing an anaglyph 3D image. Methods: Visual functions were examined before and after viewing a 2D image and an anaglyph 3D image with red-green glasses on seventy college students (mean age = 22.29${\pm}$2.19 years). Visual function tests were carried out for von Graefe phoria test, accommodative amplitude test by (-) lens addition, negative relative accommodation (NRA) and positive relative accommodation (PRA) test, negative relative convergence (NRC) and positive relative convergence (PRC) test, accommodative facility, and vergence facility test. Results: Assessment of the visual functions indicated that near exophoria and accommodative amplitude were reduced after viewing a 3D image, and although there were small changes in relation to these findings, NRC and PRC showed tendencies to increase and decrease at near, respectively. There were no significant changes with NRA and PRA, and accommodative and vergence facility were shown to have improved. Conclusions: Changes of visual functions were more in the 3D image than the 2D image, especially at near than distance. Particularly, the improvement of accommodative and vergence facility could be related to an effect of subsequent accommodation and vergence shift to have stereopsis in the 3D image. These results indicate that an anaglyph 3D image may, to some extent, be the effect of vision training such as anaglyphs.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.3
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• pp.287-291
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• 2010

Purpose: The aim of this study was to compare binocular functions such as near point of convergence (NPC), AC/A ratios, heterophoria, accommodation, accommodation lag, positive relative accommodation (PRA), negative relative accommodation (NRA), positive relative convergence (PRC), negative relative convergence (NRC) in normal subjects and convergence insufficiency. Methods: 86 subject (male n=45, female n=41, mean $age{\pm}SD=23.27{\pm}2.85$ years) without amblyopia, strabismus, and ocular pathology were studied. Forty three patients each group were classified as normal subjects and convergence insufficiency group based on AC/A ratio and far and near phoria. Binocular function of the two groups was measured using phoropter. r. Results: The values between normal subjects and convergence insufficiency were 5.71 cm and 7.07 cm for NPC, 5.28 and 2.81 for Heterophria AC/A, 0.92 exo/3.36 exo and 2.17 exo/10.84 exo for far and near phoria, 15.49/23.30/13.30 and 13.50/20.02/9.09 for PRC, respectively. However, there were no significant differences between normal subjects and convergence insufficiency for accommodative amplitude, accommodative lag, PRA, NRA, BI vergence test, BO vergence test, NRC. Conclusions: Both groups were a significant difference for cover test, NPC, Heterophria AC/A, far and near phoria, break point of PRC, and recovery point of PRC.

• BMB Reports
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• v.30 no.5
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• pp.356-361
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• 1997

We cloned a cDNA (pPRC-1) which was comprised of 841 nucleotides from the cDNA library of a male ICR mouse submandibular gland ($SMG^+$). The nucleotide sequences of pPRC-1 were identical to those of exons 2 and 3 of the mGK-21 gene, a potentially functional glandular kallikrein identified in a Balb/c mouse, except for one nucleotide residue. Although this substitution changes Ile (ATT) in pPRC-1 to Val (GTT) in mGK-21, this difference has been explained by strain polymorphism. From the amino acid sequences predicted from its cDNA, we speculated that mGK-21 gene products/pGK21 consist of 261 amino acids including the $NH_2$-terminal signal peptide (residues 1~17), the short propeptide (residues 17~24), and the active peptide (residues 25~261). Although we did not demonstrate the enzyme activity of pGK21, it was assumed that pGK 21 was involved in the maturation of certain bioactive polypeptide(s) in mouse SMG for the following reasons : (a) mGK-21 gene was apparently expressed in a male ICR mouse SMG: (b) the proposed active site $His^{65}$, $Asp^{120}$, and $Ser^{213}$ residues were completely conserved in pGK21 just like other glandular kallikreins; (c) the cloned cDNA was translated to a predicted 27 kDa polypeptide chain in vitro: (d) the 27 kDa polypeptide chain produced by CHO cells was produced to a putative active form by trypsin.

• The Korean Journal of Physiology
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• v.28 no.2
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• pp.225-231
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• 1994

The present study was undertaken to investigate the role of endogenous nitric oxide in renin release under different physiological conditions. In the first series of experiments, renin release was either inhibited by acute volume-expansion (VE) or stimulated by clipping one renal artery in the rat. VE was induced by intravenous infusion of saline (0.9% NaCl) up to 5% of the body weight over 45 min under thiopental (50 mg/kg, IP) anesthesia. VE caused a decrease of plasma renin concentration (PRC). With $N^G-nitro-L-arginine$ methyl ester $(L-NAME,\;5\;{\mu}g/kg\;per\;min)$ superadded to VE, PRC decreased further. The magnitude of increase in plasma atrial natriuretic peptide levels following VE was not affected by the L-NAME. In two-kidney, one clip rats, L-NAME-supplementation resulted in a decrease, and L-arginine-supplementation an increase of PRC. Plasma atrial natriuretic peptide levels were significantly lower in the L-arginine group than in the control. Blood pressure did not differ among the L-NAME, L-arginine, and control groups. In another series of experiments, the renin response to a blockade of NO synthesis was examined using in vitro preparations from isolated renal cortex. L-NAME significantly increased basal renin release, although it was without effect on the isoproterenol-stimulated release. These findings suggest that endogenous nitric oxide significantly contributes to the renin release. Since many factors may affect the renin release in vivo, an interaction between NO and renin under various pathophysiological states is to be further defined.

• Journal of Advanced Navigation Technology
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• v.6 no.2
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• pp.130-137
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• 2002

We present Space-Time Trellis Coded Code Division Multiple Access systems, which maintain the full diversity and coding gain of Space-Time Trellis Codes(STTC) and have the immunity to performance degradation caused by multipath fading. These STTC CDMA systems are constructed by adding the spreading and despreading processes of PN codes to STTC systems. In multipath fading channels, delay spreaded signals are detected and combined, then decoded. According to the combining and decoding methods, there are four decoding methods. There are optimum ML decoding without combining, adding multipath signals in each receive antenna before decoding, combining multi path signals in each antenna before decoding, and combining all received signals before decoding. Performance of these methods is proportional to complexity. Besides, all methods are shown to compensate the irreducible error rate which appears in multipath fading channels.

• The Journal of the Korea Contents Association
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• v.3 no.2
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• pp.65-72
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• 2003

In this paper, the new scheme using a Combined Cache(CC) that combing the Paging and Routing Cache(PRC) and an alternative handoff method according to the type of data transmission for achieving the efficient realtime communication. The PRC and quasi-soft handoff method reduce the path duplication. But they increase the network traffic load because of the handoff state packet of Mobile Host(MH). Moreover the use the same handoff method without differentiating the type of transmission data. Those problems are solved by operating U with a semi-soft handoff method for realtime data transmission and with a hard handoff method for non-realtime data transmission. As a result or simulation a better performance is obtained because of the reduction of the number of control packet in case that the number of cells are below 20. And the packet arrival time and loss of packet decreased significantly for realtime data transmission.