• Nuclear Engineering and Technology
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• v.53 no.2
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• pp.386-392
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• 2021

MACCS (MELCOR Accident Consequence Code System), WinMACCS, and MelMACCS now facilitate a multi-unit consequence analysis. MACCS evaluates the consequences of an atmospheric release of radioactive gases and aerosols into the atmosphere and is most commonly used to perform probabilistic safety assessments (PSAs) and related consequence analyses for nuclear power plants (NPPs). WinMACCS is a user-friendly preprocessor for MACCS. MelMACCS extracts source-term information from a MELCOR plot file. The current development can combine an arbitrary number of source terms, representing simultaneous releases from a multi-unit facility, into a single consequence analysis. The development supports different release signatures, fission product inventories, and accident initiation times for each unit. The treatment is completely general except that the model is currently limited to collocated units. A major practical consideration for performing a multi-unit PSA is that a comprehensive treatment for more than two units may involve an intractable number of combinations of source terms. This paper proposes and evaluates an approach for reducing the number of calculations to be tractable, even for sites with eight or ten units. The approximation error introduced by the approach is acceptable and is considerably less than other errors and uncertainties inherent in a Level 3 PSA.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.57-57
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• 2023

최근 심각한 기후변화로 인한 호우, 태풍 등 기상현상의 변화로 다양한 재해가 발생하고 그로 인한 피해 규모도 커지고 있다. 현재 우리나라의 호우 재해에 대한 예보는 단순히 강수량, 강설량, 바람의 강도 등을 전달해 주고 있는데, 이러한 정보 전달의 형태는 그로 인한 피해 규모를 예측하기 어렵다. 본 시스템은 현재의 단순한 수치만을 보여주는 예보에서 호우가 어느 지역에 어떠한 영향을 미치는지에 대한 정보를 전달한다. 시간대별 격자단위(1km×1km)로 구획하여 그 영향이클 것이라고 예상되는 9개 분야(생활, 도로, 농업, 편의, 공업, 의료복지, 교육연구. 축산업, 공용)의 정보를 전달 해 줌으로써 경제적, 산업적 측면에서 재난으로 인한 피해를 최소화할 수 있도록 하였다. GIS와 호우위험영향도 분석결과를 제공하는 플랫폼이며 주요 기능은 종합위험등급 현황을한 눈에 볼 수 있는 GIS 대쉬보드 상황판과 IBH-HR(예측강우분석), IBF-G(수문분석), IBF-PRA(리스크 분석) 3개의 분석 모듈 그리고 분석 모듈을 통해 도출된 분석결과를 관리하는 ARM(분석이력관리)으로 구성되었다. 다양한 콘텐츠 서비스로 호우 영향정보의 활용성이 클 것으로 기대된다.

• Journal of Digital Convergence
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• v.12 no.8
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• pp.467-474
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• 2014

Augmented reality in the smart environments is the interaction between the user and the media through the expansion of a variety of experiences is provided. How to use the location information, how to use markers, utilizing real-time marker-less interaction with the real world and the virtual world, such as the mapping method intermediary situated in real-time. Expansion of the elements of experience, and augmented reality as a tool of information being utilized. Educational Edutainment AR card to take advantage in terms of content was a real-time marker-less approach to create an image map image map was constructed urbanization. Stereoscopic 3D environment, taking advantage of the object produced by combining augmented reality and way of interaction, educational content. Help in terms of active and passive involvement pra realistic interest leads to a way of giving tangible.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.6
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• pp.804-811
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• 2018

Objective: Complete mtDNA D-loop sequences of four Thai indigenous chicken varieties, including Pra-dhu-hang-dam (PD), Leung-hang-khao (LK), Chee (CH), and Dang (DA) were explored for genetic diversity and relationships with their potential ancestor and possible associates to address chicken domestication in Thailand. Methods: A total of 220 complete mtDNA D-loop sequences of the four Thai indigenous chicken varieties were obtained by Sanger direct sequencing of polymerase chain reaction amplicons of 1,231 to 1,232 base pair in size. A neighbor-joining dendrogram was constructed with reference complete mtDNA D-loop sequences of Red Junglefowl (RJF) and those different chicken breeds available on National Center for Biotechnology Information database. Genetic diversity indices and neutrality test by Tajima's D test were performed. Genetic differences both within and among populations were estimated using analysis of molecular variance (AMOVA). Pairwise fixation index ($F_{ST}$) was conducted to evaluated genetic relationships between these varieties. Results: Twenty-three identified haplotypes were classified in six haplogroups (A-E and H) with the majority clustered in haplogroup A and B. Each variety was in multiple haplogroups with haplogroups A, B, D, and E being shared by all studied varieties. The averaged haplotype and nucleotide diversities were, respectively 0.8607 and 0.00579 with non-significant Tajima's D values being observed in all populations. Haplogroup distribution was closely related to that of RJF particularly Gallus gallus gallus (G. g. gallus) and G. g. spadiceus. As denoted by AMOVA, the mean diversity was mostly due to within-population variation (90.53%) while between-population variation (9.47%) accounted for much less. By pairwise $F_{ST}$, LK was most closely related to DA ($F_{ST}=0.00879$) while DA was farthest from CH ($F_{ST}=0.24882$). Conclusion: All 4 Thai indigenous chickens are in close relationship with their potential ancestor, the RJF. A contribution of shared, multiple maternal lineages was in the nature of these varieties, which have been domesticated under neutral selection.

• Parasites, Hosts and Diseases
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• v.26 no.2
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• pp.121-126
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• 1988

Efficacy of praBiquantel (CesocideB injection) by intramuscular (1.M.) route against cestode infections was evaluated. Total 93 domestic or laboratory animals such as dogs, cats, rats, mice, goats, deers and chickens were used. Animals were infected with Dipylidium caninum, Spirometra sp. , Taenia pisiformis, Taenia taeniaeformis, Hymenolepis nana, Moniegia expanse, Moniexia sp. or Raillietina sp. A single dose of prasiquantel, 6 mg/kg of body weight, was highly effective (97.9%) against cestodes of various kinds disregarding the host species or their intensity of infection. At higher dose above 6 mg/kg, the cure rate was 100%. All the cestodes treated were expelled from the host within 48 hours. The discharged proglottides were damaged severely except Hymenolepis nana and Moniegia expanse. Intramuscular injection of this drug evoked a brief pain response in a dog, but no other side reactions were observed.

• Journal of Korean Society on Water Environment
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• v.36 no.3
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• pp.220-228
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• 2020

Anaerobic ammonium oxidation (AMX) is a cost-efficient biological nitrogen removal process. The coexistence of ammonia-oxidizing bacteria (AOB) in an AMX reactor is an interesting research topic as a nitrogen-related bacterial consortium. In this study, a sequencing batch reactor for AMX (AMX-SBR) was operated with a conventional activated sludge. The AOB in an AMX bioreactor were identified and quantified using terminal restriction fragment length polymorphism (T-RFLP) and real-time qPCR. A T-RFLP assay based on the ammonia monooxygenase subunit A (amoA) gene sequences showed the presence of Nitrosomonas europaea-like AOB in the AMX-SBR. A phylogenetic tree based on the sequenced amoA gene showed that AOB were affiliated with the Nitrosomonas europaea/mobilis cluster. Throughout the enrichment period, the AOB population was stable with predominant Nitrosomonas europaea-like AOB. Two OTUs of amoA_SBR_JJY_20 (FJ577843) and amoA_SBR_JJY_9 (FJ577849) are similar to the clones from AMX-related environments. Real-time qPCR was used to quantify AOB populations over time. Interestingly, the exponential growth of AOB populations was observed during the substrate inhibition of the AMX bacteria. The specific growth rate of AOB under anaerobic conditions was only 0.111 d^-1. The growth property of Nitrosomonas europaea-like AOB may provide fundamental information about the metabolic relationship between the AMX bacteria and AOB.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.1
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• pp.735-743
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• 2015

The service oriented architecture assures flexibility of enterprise application development, so it supports agile reaction to business change. On the other hand, considerable effort is needed to develop a service by combining business and constraint consumes because the entire combination logic should be changed according to the change in business rule. To improve the current method, this paper applied an aspect oriented approach to service system development. In this paper, the rule concern is proposed in addition to the core concern and cross cutting concern of aspect oriented approach. The rule concern is extracted from business rules included in the business processes and services. The rule concern is classified into the process rule aspect and service rule aspect according to the level of the rule. In the proposed approach, system is modularized into the core concern, cross cutting concern and rule concern through separation of concern, and they are maintained independently. Therefore, the adaptability, reusability, and maintainability of a service system will be enhanced.

• Journal of Korean society of Dental Hygiene
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• v.12 no.5
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• pp.861-870
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• 2012

Objectives : This study has made a comparison of the difference between the periodontal parameter before and after applying dental hygiene process on patients requiring supportive periodontal therapy at a private dental clinic. Methods : The entire process was conducted on 74 patients. As a result of analyzing the difference in periodontal parameters such as PPD>4mm, BOP, and O'Leary Index of 29 patients that has completed 1 circle of dental hygiene process. Results : All periodontal parameters in all subject patients had been significantly reduced(p<0.05). Furthermore, as a result of comparing the periodontal conditions of the smoking group and non-smoking group, complier and non-complier, all parameters were reduced with a significant difference in the non-smoking group and the complier, but the smoking group and the non-complier did not show difference in all parameters. As a result of making an assessment of before and after dental hygiene process according to PRA classifications, high risk group has been generally changed to moderate or low risk group. Conclusions : Accordingly, the supportive periodontal therapy applying dental hygiene process has been shown to be effective. The dental hygiene process in periodontal patients who require continuous management is anticipated to be a very efficient process.

• Journal of Microbiology and Biotechnology
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• v.27 no.5
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• pp.1010-1022
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• 2017

Hybrid histidine kinase is part of a two-component system that is required for various stress responses and pathogenesis of pathogenic fungi. The Tco1 gene in human pathogen Cryptococcus neoformans encodes a hybrid histidine kinase and is important for pathogenesis. In this study, we identified a Tco1 homolog, UmTco1, in the maize pathogen Ustilago maydis by bioinformatics analysis. To explore the role of UmTco1 in the survival of U. maydis under environmental stresses and its pathogenesis, ${\Delta}umtco1$ mutants were constructed by allelic exchange. The growth of ${\Delta}umtco1$ mutants was significantly impaired when they were cultured under hyperosmotic stress. The ${\Delta}umtco1$ mutants exhibited increased resistance to antifungal agent fludioxonil. In particular, the ${\Delta}umtco1$ mutants were unable to produce cytokinesis or conjugation tubes, and to develop fuzzy filaments, resulting in impaired mating between compatible strains. The expression levels of Prf1, Pra1, and Mfa1, which are involved in the pheromone pathway, were significantly decreased in the ${\Delta}umtco1$ mutants. In inoculation tests to the host plant, the ${\Delta}umtco1$ mutants showed significantly reduced ability in the production of anthocyanin pigments and tumor development on maize leaves. Overall, the combined results indicated that UmTco1 plays important roles in the survival under hyperosmotic stress, and contributes to cytokinesis, sexual development, and virulence of U. maydis by regulating the expression of the genes involved in the pheromone pathway.

• Journal of Microbiology and Biotechnology
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• v.29 no.11
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• pp.1806-1816
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• 2019

Candida albicans is an opportunistic fungus possessing multiple virulence factors controlling pathogenicity. Cell wall proteins are the most important among these factors, being the first elements contacting the host. Ddr48 is a cell wall protein consisting of 212 amino acids. A DDR48 haploinsufficient mutant strain was previously found necessary for proper oxidative stress response and drug resistance. In this study, we aimed to further elucidate the role of Ddr48 by performing additional phenotypic characterization assays. A combinatory proteomic and bioinformatics approach was also undertaken to determine differentially expressed cell wall proteins. Results showed that the mutant strain exhibited a 10% decrease in adhesion mirrored by a 20% decrease in biofilm formation, and slight sensitivity to menadione, diamide, and SDS. Both strains showed similar hyphae formation, virulence, temperature tolerance, and calcofluor white and Congo red sensitivities. Furthermore, a total of 8 and 10 proteins were identified exclusively in the wild-type strain grown under filamentous and non-filamentous conditions respectively. Results included proteins responsible for superoxide stress resistance (Sod4 and Sod6), adhesion (Als3, Hyr4, Pmt1, and Utr2), biofilm formation (Hsp90, Ece1, Rim9, Ipp1, and Pra1) and cell wall integrity (Utr2 and Pga4). The lack of detection of these proteins in the mutant strain correlates with the observed phenotypes.