• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.12
• /
• pp.4863-4867
• /
• 2015

Background: Triple negative breast cancer (TNBC), characterized as estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 Her2 negative and accounting for 10-17% of all breast carcinomas, is only partially responsive to chemotherapy and suffers from a lack of clinically established targeted therapies. The aim of the current study was to evaluate the patterns of treatment and clinicopathology figures in Kurdish patients with triple-negative breast cancer, and to compare these to other reports. Materials and Methods: Between 2001 and 2014, 950 breast cancer patients were referred to our clinic. There were 74 female patients with TNBC, including 70 patients was invasive ductal carcinoma entered into our study. ER and PR positivity was defined as positive immunohistochemical staining in more than 10% of tumor cells. Immunohistochemistry assay with anti-HER2 antibodies was used to identify HER negative (0 and 1+) or positive (2+ and 3+). HER2 gene amplification was determined by fluorescent in situ hybridization (FISH). Overall survival (OS) was plotted with GraphPad Prism 5 Software using Kaplan-Meier and log-rank tests for comparison of results. Results: The mean age in the first diagnosis for 70 patients with triple TNBC and invasive ductal carcinoma was 49.6 years that range of age was 27-82 years. All of the patients were female. Of 70 patients, 23 patients had metastasis. Thirty-two patients (45.7%) were treated with tamoxifen and 39 (55.7%) with radiotherapy. Three-year, 5-year and 10-year OS rates for all patients were 82%, 72% and 64%, respectively. Conclusions: The OS in our West Iran TNBC patients is less than reported elsewhere. However, treatment with combination of tamoxifen plus radiation increases the OS and reduces the mortality rate.

• Journal of Digital Convergence
• /
• v.14 no.3
• /
• pp.105-114
• /
• 2016

As the media environment surrounding us has changed rapidly, the influences of traditional media decrease whereas promotions using new media have been developing remarkably, Under this circumstance, cross-media advertising, which strategically integrates advertisements on multiple media, is getting attention as an effective marketing communication approach. This study investigated consumer responses to cross-media advertising using both online and offline media, focusing on the effects of product involvement, attributes of media connection, and gender. The experiment was conducted towards adult consumers aged 20 to 39. Results confirmed that the interaction effect between product involvement and attributes of media connection on brand attitude and behavioral intention was significant by a moderating role of gender. Based on the results from this study, both theoretical and practical implications were discussed, as were directions for future research.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.4 no.2
• /
• pp.100-105
• /
• 2004

The influencing factors on the OPC (optical proximity correction) results are quantitatively analyzed using OPCed L/S patterns. ${\sigma}$ values of proximity variations are measured to be 9.3 nm and 15.2 nm for PR-A and PR-B, respectively. The effect of post exposure bake condition is assessed. 16.2 nm and 13.8 nm of variations are observed. Proximity variations of 11.6 nm and 15.2 nm are measured by changing the illumination condition. In order not to seriously deteriorate the OPC, these factors should be fixed after the OPC rules are extracted. Proximity variations of 11.4, 13.9, and 15.2 nm are observed for the mask mean-to-targets of 0, 2 and 4 nm, respectively. The decrease the OPC grid size from 1 nm to 0.5 nm enhances the correction resolution and the OCV is reduced from 14.6 nm to 11.4 nm. The enhancement amount of proximity variations are 9.2 nm corresponding to 39% improvement. The critical dimension (CD) uniformity improvement for adopting the small grid size is confirmed by measuring the CD uniformity on real SRAM pattern. CD uniformities are measured 9.9 nm and 8.7 nm for grid size of 1 nm and 0.5 nm, respectively. 22% improvement of the CD uniformity is achieved. The decrease of OPC grid size is shown to improve not only the proximity correction, but also the uniformity.

• Physical Therapy Korea
• /
• v.19 no.3
• /
• pp.31-39
• /
• 2012

The lower trapezius muscle is an important stabilizer and primary mover of the scapula. The potential use of ultrasound imaging to evaluate scapular muscle function warrants investigation. The purpose of this study is to use ultrasound imaging for determining the effectiveness of 4 different isometric exercises for maximally activating the lower trapezius muscles in healthy subjects. Twenty-eight (14 men and 14 women) volunteers were recruited for this study. Thickness measurements of the lower trapezius muscles were recorded during 4 exercises: latissimus pulldown (LP), prone V-raise (PV), prone row (PR), and modified prone cobra (MP). Lower trapezius muscle thickness was measured 3 times by 2 investigators at a point 3 cm lateral to the lateral edge of the T8 spinous process. The order of 4 exercise execution was randomized for each participant. To identify statistical significance, one-way ANOVA with repeated measures was used with the significance level of .05. Intraclass correlation coefficient (ICC) for intra-reliability was .86~.98 and inter-rater reliability .83~.96 for the lower trapezius, respectively (p<.01). Thickness changes in the lower trapezius muscles between the relaxed and contracted states in men were as follows: LP ($7.37{\pm}2.68mm$, 182%), MP ($4.69{\pm}1.74mm$, 167%), PV ($4.52{\pm}1.47mm$, 149%), and PR ($3.84{\pm}1.72mm$, 133%). In women the values were as follows: LP ($4.64{\pm}1.24mm$, 163%), MP ($2.79{\pm}.81mm$, 131%), PV ($2.78{\pm}.85mm$, 129%), and PR ($2.21{\pm}1.26$ mm, 100%). Thickness of the lower trapezius muscles significantly differed between exercises in both the gender (p<.01). The LP was the most effective exercise for increasing the activation of the lower trapezius muscle in both the gender. We recommend performing the LP exercise for strengthening the lower trapezius muscles.

• Journal of Nutrition and Health
• /
• v.34 no.2
• /
• pp.222-229
• /
• 2001

This study describes the application of the stages of change construct to fat intake by examining the associations of the stages of change with nutritional status and beliefs on health behavior. Data were obtained from apparently healthy 596 adults(326 females and 270 males) residing in large cities. Stages of change assessed by an algorithms based on 6 items were designed each subject into one of the 5 stages: precontemplation(PC), contemplation(CO), preparation(PR), action(AC) and maintenance(MA). Beliefs on health behavior were assessed by self efficacy as well as 4 belief scales from the Locus of Illness Control(LIC) developed using factor analysis such as internal disease cure and prevention and external disease cure and prevention. Energy and fat intakes were measured by a 39 item short form food frequency questionnaire. Regarding the 5 stages of change, MA stage comprised the largest group(37.9%), followed by Ac(30.7%), PC(11.4%), CO(10.4%) and PR(9.6%). Subjects who were females, older or healthier were more likely to belong to either AC or MA. Stage assignment of individuals was corroborated by their nutritional variables. Those in PC had the most energy and fat and those in MA ate the least for females. BMI was higher in PR than any other stages for both males and females. Those in PC were distinctive in that they were more externally oriented in terms of health control showing higher scores on external disease prevention(for males) and external disease cure(for females), and lower score on internal disease cure. On the other hand, those in MA received the highest scores on internal disease prevention and self efficacy, which suggested that they were more internally oriented. Canonical discriminant function analysis indicated that the 5 stages were importantly discriminated by BMI, self efficacy, internal disease prevention and external disease prevention for males and by fat intake, self efficacy and external disease cure variables for females. The results of our study confirm differences in stages of change in fat intake in terms of nutritional status and beliefs on heath behavior and indicate the need for taking these phases of change into account in nutrition advice. (Korean J Nutrition 34(2) : 222-229, 2001)

• Journal of Korean Dental Hygiene Science
• /
• v.5 no.2
• /
• pp.97-104
• /
• 2022

Background: Due to the declining number of students preparing for university entrance exams , the quota of universities has been decreasing continuously. This situation became increasingly diverse as new media used online, mobile, and PR tools to continuously invite students. This study is aimed at offering the helpful data to plan an effective PR strategy by analyzing the correlation between the major selection and satisfaction of the department's social media usage among freshmen majoring in dental hygiene. Methods: The collected data from the self-reported survey with freshmen were analyzed using the SPSS 22.0 program. The survey items were motive to select the major, social media platform that subjects used, reasons to use the media, time to visit the department's social media platform, and satisfaction level on the department's social media platform, using a 5-point Likert Scale. Results: The reasons for choosing a major were given by 32.2% and 15.9% respondents, respectively, as the vision after graduation and practice facilities. 39.9% and 31.4% used Instagram and YouTube for social media platforms, respectively, for using social media platform; 26.9% and 26.3% visited the department's social media before and after entering the university, respectively; 46.4% and 24.9% used Instagram and YouTube for department social media; and they generally satisfied with the contents of the department's social media. 40.9% of them said that information from the department's social media was useful. 33.8% of them said the information from the department's social media exceeded their expectations. 46.8% of them answered that the department's social media made the department's image positive. 33.4% got interested in the major more due to the department's social media. According to 32.1% of respondents, the department's social media was helpful in deciding on a major. With 35.4%, a positive correlation was discovered between the department's practice facilities and satisfaction on the department's social media. Conclusion: It is thought that the department's social media should try continuously by uploading the contents to meet the users' needs on a regular basis and seeking the plans to be able to collect various opinions using surveys through the related social media so that students can select the major and, moreover, lead the positive direction to adapt the university life under the unfamiliar environment after admission.

• Journal of the Korean Ceramic Society
• /
• v.39 no.12
• /
• pp.1128-1132
• /
• 2002

$ReMnO_3$(Re:Y, Ho, Er) thin films were prepared by MOCVD method available to non-volatile memory device with MFS-FET structure. $ReMnO_3$ thin films were deposited on the Si(100) substrate at 700${\circ}C$ for 2h. When the films were post-annealed at 900${\circ}C$ for 1h in air, the single phase of hexagonal $ReMnO_3$ thin films were detected. Ferroelectric properties of $ReMnO_3$ thin films were dependent on the degree of c-axis orientation in the single phase of hexagonal structure and remnant polarization (Pr) of $YMnO_3$ thin films with high degree of c-axis orientation was 105 nC/$cm^2$. Leakage current density was dependent on the grain size of microstructure and that of $YMnO_3$ thin films with grain size of 100∼150 nm was $10^{-8}$ A/$cm^2$ at applied voltage of 0.5 V.

• Journal of the Korean Chemical Society
• /
• v.36 no.2
• /
• pp.205-211
• /
• 1992

The $2{\nu}_{C=0}$ + amide III combination band spectrum of acetamide (AA) was obtained in very dilute solutions of AA+lanthanide shift reagents (LSR) in carbon tetrachloride over the range of $15^{\circ}$ to $45^{\circ}C$. It was found that only 1 : 1 AA-LSR complex is formed by the interaction between carbonyl oxygen of AA and central metal ion(Ln(Ⅲ)) in LSR. The thermodynamic parameters for Ln(III)${\cdot}$O=C bond were determined by computer analysis of concentration and temperature dependent spectra. ${\Delta}H^{\circ}$ for the coordination of AA to Eu$(dpm)_3$, Yb$(dpm)_3$, and Pr$(dpm)_3$ have been found to be -39.1, -28.4, and -25.5 kJ/mol, respectively. It has shown that this type of ion-dipole interaction is more than twice stronger compared to the dipole-dipole interaction in the amide linkage, and largely depending on the steric hindrence effect by the bulky dpm groups around central metal ion (Ln(III)) rather than the ionic potential effect of central metal ion itself.

• Journal of the Korean Geotechnical Society
• /
• v.39 no.3
• /
• pp.5-16
• /
• 2023

The effect of raft flexibility on piled raft foundations in sandy soil was investigated using a numerical analysis and an analytical study. The investigation's emphasis was the load sharing between piles and raft following the raft rigidity (K_R), end-bearing conditions. The case of individual piles and subsequently the response of groups of piles was analyzed using a 3D FEM. This study shows that the α_pr, load-sharing ratio of piled raft foundations, decreases as the vertical loading increases and as the K_R decreases. This tendency is more obvious when using friction piles compared to using end-bearing piles. The effect of raft rigidity is found to be more significant for the axial force distribution - each pile within the foundations has almost similar axial forces of the pile head with a flexible raft; however, each pile has different values with rigid rafts, especially with the end-bearing piles. The axial force of the pile base with floating piles shows similar point-bearing resistance for all the piles; however, it shows different values with end-bearing piles. The differential settlement ratio of rafts showed a larger value with lower K_R.

• Journal of the Korean Society for information Management
• /
• v.39 no.4
• /
• pp.159-189
• /
• 2022

The research aims to recommend strategies to promote PR activities of 'the Memory of the World(MoW)' on the websites. To achieve the goal, the researchers analyzed the current conditions of online PRs of the MoW in S. Korea by developing the standards/elements for analysis. The research examined the two main concepts of MoW and extracted the three core standards/elements for evaluating current online PRs of MoW through reviewing earlier studies: contents of PRs, ways of PRs, and features of media. The research examined PR activities on the 21 websites of 11 institutions which manage MoW in South Korea. The research found the significant features of the online PRs and suggested detailed strategies for improving the online PRs of MoW: first, it is required to emphasize the values of both preservation and utilization of MoW equally. Second, it is necessary to promote the PRs of MoW by using the way of 'user segmentation'. Third, it needs to develop the unit systems and/or services to integrate with related documentary heritages so that users can access documentary heritages effectively and efficiently. Finally, it is required to develop the guidelines or/and manuals to conduct and promote the PRs of the MoW by providing specific directions and methods of publicities.