• 제목/요약/키워드: PQ

검색결과 362건 처리시간 0.021초

생쥐에서 Aminotriazole이 Paraquat의 신독성에 미치는 영향

  • 정지숙;이병래;노영복
    • 한국동물학회지
    • /
    • 제37권1호
    • /
    • pp.97-103
    • /
    • 1994
  • Catalase 억제제로 알려져 있는 AT가 Pn에 중독된 생쥐 생존율을 유의하게 감소시켰다. 생쥐의 간장 폐 및 신장에서 catalase 활성도가 현저히 감소되었으며, PQ와 AT 병합투여군에서 Catalase 활성은 PQ 단독투여 군에 비하여 유의한 감소를 나타냈으나 glutathione량과 SOD 활성은 PQ 단독투여군과 유의한 차이를 나타내지 않았다. 또한 광학현미경 검색상 PQ 단독투여 군에서 사구체와 요세관이 손상되었으나 AT의 병합투여군에서 사구체와 요세관의 손상이 더욱 증가됨을 보여주고 있다. 이상의 실험 결과로 PQ의 신독성이 AT 병합투여로 더욱 증가됨을 알 수 있는데 이러한 결과는 AT가 신장 Catalase를 억제하여 증가된 과산화수소에 의해 나타난 독성의 결과로 생각되며, 과산학수소는 Haber-Weiss 반응이나 trenton 반응 또는 paraquat radical과 직접 반응하여 hydroxvl radicals을 생성하므로 PQ 독성은 과산화수소의 생성과 관련이 있는 것으로 추정된다.

  • PDF

고성능 콤팩트형 AC모터드라이브 고조파 필터 제안 (A Proposal of Compact Passive Harmonic Filter for ac Motor Drive)

  • 박병주;윤동철;오정철;배병열;황안일;유항규;최석근
    • 전기학회논문지P
    • /
    • 제67권4호
    • /
    • pp.191-199
    • /
    • 2018
  • The harmonic reduction method of ac motor drive, ACL and DCL were commonly used, but the current distortion ratio was only 35%, thus the several different types of filters as BBHF(broad band harmonic filter), HHF(hybrid harmonic filter), NHHF(new hybrid harmonic filter) have been developed to satisfy the IEEE Std. 519 harmonic limitation. However, these filters had been limited marketability due to cost and size problems. This study suggests the methods to reduce cost and size of the harmonic filter including topologies, besides we discussed simulation results of the power system with regard to the implementation and performance of the filters.

Effects of Paraquat on Ascorbic Acid and Malondialdehyde Contents, and Superoxide Dismutase Activity in Spinach Chloroplasts under Light and Dark

  • Won-Hyuck Park;Yang-Hee Chang
    • 한국환경과학회지
    • /
    • 제1권2호
    • /
    • pp.81.1-86
    • /
    • 1992
  • The amounts of ascorbic acid in chloroplasts treated with light and light+paraquat (PQ) were reduced by 81 and 82% of initial level, respectively at 24 hr at incubation. And those treated with dark and dark+PQ were decreased by W and 55% of the original level, respectively. Malondialdehyde (MDA) contents at 24 hr of dark and dark+PQ treatment were increased by 6 and 31% of the initial level, respectively. When chloroplasts were treated with light and light+PQ, MDA contents after 24 hr were increased by 88 and 146% of the initial level, respectively. SOD activities treated with light and light+PQ were increased by 10 and 20% of the initial level, respectively for 3 hr and thereafter reduced by 46 and 49% of the original level, respectively at 24 hr. However, the SOD activities treated with dark and dark+PQ were decreased by 37 and 30% of the initial level, respectively. It is considered that PQ triggers the oxidation of ascorbic acid, the induction of lipid peroxidation and the inactivation of SOD under light so that PQ has inhibitors effect on the pathway of plant metabolism. Key word: ascorbic acid, malondialdehyde, superoxide dismutase, paraquat, lipid peroxidation.

  • PDF

Effects of Paraquat on Ascorbic Acid and Malondialdehyde Contents, and Superoxide Dismutase Activity in Spinach Chloroplasts under Light and Dark

  • Park Won-Hyuck;Chang Yang-Hee
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
    • /
    • 제1권2호
    • /
    • pp.81-86
    • /
    • 1997
  • The amounts of ascorbic acid in chloroplasts treated with light and light+paraquat (PQ) were reduced by 81 and $82\%$ of initial level, respectively at 24 hr at incubation. And those treated with dark and dark+PQ were decreased by 46 and $55\%$ of the original level, respectively. Malondialdehyde (MDA) contents at 24 hr of dark and dark+PQ treatment were increased by 6 and $31\%$ of the initial level, respectively. When chloroplasts were treated with light and light+PQ, MDA contents after 24 hr were increased by 88 and $146\%$ of the initial level, respectively. SOD activities treated with light and light+PQ were increased by 10 and $20\%$ of the initial level, respectively for 3 hr and thereafter reduced by 46 and $49\%$ of the original level, respectively at 24 hr. However, the SOD activities treated with dark and dark+PQ were decreased by 37 and $30\%$ of the initial level, respectively, It is considered that PQ triggers the oxidation of ascorbic acid, the induction of lipid peroxidation and the inactivation of SOD under light so that PQ has inhibitory effect on the pathway of plant metabolism.

  • PDF

AHP를 이용한 실시간 전력품질 평가기법 (Real-Time Power Quality Evaluation by using Analytic Hierarchy Process)

  • 이범
    • 한국전자통신학회논문지
    • /
    • 제17권1호
    • /
    • pp.85-90
    • /
    • 2022
  • 본 연구에서는 소비자의 부하를 반영하여 실시간 전력품질을 평가할 수 있도록 하는 방법을 개발하였다. 이를 위하여 전력품질 상태를 [Ideal], [Measured], [Acceptable]로 분류하고, Ideal AHP를 사용하여 측정값이 어느 정도인지를 평가할 수 있도록 하였으며, 소비자 부하특성을 반영할 수 있도록 부하를 저항부하, 전동기부하, 전자제품부하로 분류하고 부하의 특성을 반영한 전력품질을 평가할 수 있도록 하였다. 향후, 1:1 행렬과 관련한 심도 있는 연구를 진행하고, 연간단위의 전력품질과 통합하여 종합적인 전력품질 평가를 할 계획이다.

The Activities of Antioxidant Enzymes in Response to Oxidative Stresses and Hormones in Paraquat-tolerant Rehmannia glutinosa Plants

  • Choi, Dong-Geun;Yoo, Nam-Hee;Yu, Chang-Yeon;De Los Reyes, Benildo;Yun, Song-Joong
    • BMB Reports
    • /
    • 제37권5호
    • /
    • pp.618-624
    • /
    • 2004
  • All members of R. glutinosa show the unique characteristic of intrinsic tolerance to paraquat (PQ). Antioxidant enzymes have been proposed to be the primary mechanism of PQ resistance in several plant species. Therefore, the antioxidant enzyme systems of R. glutinosa were evaluated by comparatively analyzing cellular antioxidant enzyme levels, and their responses of oxidative stresses and hormones. The levels of ascorbate peroxidase (APX), glutathione reductase (GR), non-specific peroxidase (POX), and superoxide dismutase (SOD) were 7.3-, 4.9-, 2.7- and 1.6-fold higher in PQ-tolerant R. glutinosa than in PQ-susceptible soybeans. However, the activity of catalase (CAT) was about 12-fold higher in the soybeans. The activities of antioxidant enzymes reduced after PQ treatment in the two species, with the exception of POX and SOD in R. glutinosa, which increased by about 40%. Interestingly, the activities of APX, SOD and POX in R. glutinosa, relative to those in soybeans, were further increased by 49, 67 and 93% after PQ treatment. The considerably higher intrinsic levels, and increases in the relative activities of antioxidant enzymes in R. glutinosa under oxidative stress support the possible role of these enzymes in the PQ tolerance of R. glutinosa. However, the relatively lower levels of SOD versus PQ tolerance, and the mixed responses of antioxidant enzymes to stresses and hormones, suggest a possible alternative mechanism(s) for PQ tolerance in R. glutinosa.

AC모터드라이브 라인필터의 축소화를 위한 신형 하이브리드고조파필터 제안 (A Proposal of New Hybrid Passive Harmonic Filter for AC Motor Drive Line Filter Size Reduction)

  • 박병주;윤동철;오정철;배병열;황안일;유항규;최석근
    • 전기학회논문지P
    • /
    • 제67권1호
    • /
    • pp.1-8
    • /
    • 2018
  • ACL and DCL are have been conventionally used for reducing harmonic current on the input side of an ACMD. The current distortion ratio ITHD using ACL and DCL is only 35% to 85%, therefore to satisfy the IEEE Std. 519 requirements, the line filters has been focused as an alternative means. Those are installed between the AC power supply and the input of the ACMD, and must meet the IEEE Std. 519, be economical and be compact. To contribute to the widespread of using these line filters, we discussed concerning its topologies, simulation results, prototype test results as well as the cost evaluations. It included not only the proposed (NHHF) new hybrid harmonic filters which have both merits of simplicity and economic but also the past (BBHF) broadband harmonic filters and (HHF) hybrid harmonic filters.

Power Quality Monitoring System with a New Distributed Monitoring Structure

  • Won, Dong-Jun;Chung, Il-Yop;Kim, Joong-Moon;Ahn, Seon-Ju;Moon, Seung-Il;Seo, Jang-Cheol;Choe, Jong-Woong
    • KIEE International Transactions on Power Engineering
    • /
    • 제4A권4호
    • /
    • pp.214-220
    • /
    • 2004
  • Power quality monitoring is the cornerstone for power quality analysis, diagnosis and improvement. The measurement of power quality (PQ) evolves from instantaneous metering to continuous monitoring. Furthermore, recent technologies enable us to construct more flexible, reliable, rapid and economical power quality monitoring system (PQMS). Therefore, this paper presents an improved PQMS with a new distributed monitoring structure. The proposed PQMS consists of a PQ meter, PQ analyzer and GUI. The PQ meter only collects raw data and the PQ analyzer performs power quality analysis. It has several advantages compared to conventional structures in economic efficiency, modularity, speed, etc. PQ monitoring algorithms to catch steady-state trends and to detect PQ events are also adapted to the proposed structure. Using the proposed structure and monitoring algorithm, a prototype PQMS is constructed and real-time testing is performed.

Toxicokinetics of paraquat in Korean patients with acute poisoning

  • Kim, Hak-Jae;Kim, Hyung-Ki;Lee, Hwayoung;Bae, Jun-Seok;Kown, Jun-Tack;Gil, Hyo-Wook;Hong, Sae-Yong
    • The Korean Journal of Physiology and Pharmacology
    • /
    • 제20권1호
    • /
    • pp.35-39
    • /
    • 2016
  • To conduct a kinetic study of paraquat (PQ), we investigated 9 patients with acute PQ intoxication. All of them ingested more than 20 ml of undiluted PQ herbicide to commit suicide and arrived at our hospital early, not later than 7 h after PQ ingestion. The urine dithionite test for PQ in all of the nine patients was strongly positive at emergency room. Blood samples were obtained every 30 min for the first 2~3 h and then every 1 or 2 h, as long as the clinical progression was stable among the patients for 30 h after PQ ingestion. The area under the plasma concentration-time curve ($AUC_{inf}$), which was extrapolated to infinity, was calculated using the trapezoidal rule. Toxicokinetic parameters, such as the terminal elimination half-life, apparent oral clearance, and apparent volume of distribution ($V_d/F$) were calculated. The maximum PQ concentration ($C_{max}$) and the time to reach maximum PQ concentration ($T_{max}$) were also obtained. Plasma PQ concentrations in nine patients were well described by a bi-exponential curve with a mean terminal elimination half-life of $13.1{\pm}6.8h$. $C_{max}$ and $AUC_{inf}$ were $20.8{\pm}25.7mg/l$ and $172.5{\pm}160.3h{\cdot}mg/l$, respectively. Apparent volume of distribution and apparent oral clearance were $50.9{\pm}61.3l/kg$ and $173.4{\pm}111.2l/h$, respectively. There were a significant correlation (r=0.84; p<0.05) between the PQ amount ingested and $C_{max}$. $AUC_{inf}$ also showed a significant correlation (r=0.83; p<0.05) with the PQ amount ingested. These correlations provide evidence that PQ has dose-linear toxicokinetic characteristics.

가자(Terminalia chebulae) 메탄올 추출물이 paraquat 독성에 의한 흰 쥐의 신장 및 폐조직에 미치는 영향 (Effects of Methanol Extract from Terminalia chebulae on Renal and Pulmonary Toxicities Induced by Paraquat in Rats)

  • 박종옥
    • 생명과학회지
    • /
    • 제18권1호
    • /
    • pp.129-135
    • /
    • 2008
  • Paraquat (PQ)는 전세계적으로 사용되고 있는 제초제의 한 종류이며 독성을 가지고 있다. 가자(terminalia Chebulae)는 오래전부터 설사, 이질, 디프테리아, 기침, 천식 등의 치료제로 중국, 한국 등에서 사용되고 있는 약용식물이다. TCM이 PQ 유도독성에 미치는 영향을 실험한 결과 다음과 같은 결과들을 얻었다. 1. 신장 조직과 폐 조직에서 지질과산화물 함량을 측정해본 결과 PQ 처리군은 정상군에 비해 각각 2배, 2.5배 증가하였으나 TCM 투여군에서는 정상군에 가깝게 감소하였다. 2. 활성산소 생성계 효소에서 cytosolic enzyme system인 aldehyde oxidase, xanthine oxidase 그리고 microsomal enzyme system인 aminopyrine N-demethylase, aniline hydroxylase 활성을 측정한 결과 PQ 처리군에서 활성증가가 나타났으나 TCM 투여군에서는 효소활성이 소량 감소하였다. 3. 활성산소 해독계에 영향을 미치는 superoxide dismutase, catalase, glutathione peroxidase를 측정 한 결과 PQ 처리군은 정상군에 비해 2배 이상의 활성 증가가 나타났고 TCM 투여군의 경우 소량 감소하는 결과가 얻어졌다. 4. 폐 조직의 G-6-phosphatase는 PQ투여군의 경우 활성 저하가 나타났으나 TCM 투여군에서는 효소 활성이 점차 증가하여 300 mg/ml에서는 정상군에 가까운 수치가 나타났다. 5. 폐 조직 중의 collagen 함량은 PQ 투여군의 경우 정상군에 비해 1.5배 증가하였고 가자 메탄올추출물 투여군의 경우 100 mg/kg, 200 mg/kg, 300 mg/kg의 순서로 함량이 점차 감소하는 결과를 얻을 수 있었다. 이상의 결과를 종합하여 볼 때 가자 메탄올추출물은 PQ 유도독성을 신장 및 폐조직에서 효과적으로 경감시키는 것으로 나타났다.