• Journal of Animal Science and Technology
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• v.57 no.1
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• pp.2.1-2.5
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• 2015

Among the main intimidation to the sheep and goat population, PPR outbreaks are causing huge losses especially in endemic areas. During recent times, six outbreaks of PPR were confirmed at semi-organized goat farms/herds in various regions of Punjab province and Islamabad capital territory (ICT), Pakistan. The disease started after introduction of new animals at these farms with no history of previous PPR vaccination. The clinical signs appeared affecting respiratory and enteric systems and spread quickly. Disease caused mortality of 10-20% and morbidity of 20-40% within a time period of four weeks. Morbidity and mortality rates were 30.38% (86/283) and 15.55% (44/283), respectively. Three treatment regimes were executed to demonstrate the role of vaccination during outbreak at these farms. First was to use only the broad spectrum antibiotics (Penicillin & Streptomycin and/or Trimethoprim and Sulfadiazine) at two farms (Texilla and Attock). Second treatment regime was to use the same broad spectrum antibiotic along with extensive fluid therapy (Farms at ICT-1 and ICT-2). The third regime was to use of broad spectrum antibiotic plus fluid therapy along with vaccinating the herd against PPR during first week of outbreak (ICT-3 and ICT-4). The third scheme of treatment gave the better results as there was no mortality in third week post-outbreak. Therefore, it is suggested to give proper importance to PPR vaccination along with conventional symptomatic treatment when dealing the PPR outbreaks in endemic disease conditions.

• Journal of Animal Science and Technology
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• v.57 no.11
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• pp.32.1-32.8
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• 2015

Peste des petits ruminants (PPR) is considered to be one of the main constraints to enhancing the productivity of goats and sheep in regions where it is present and becoming endemic. PPR was recognized in Pakistan in early 1990s but got importance during the Participatory Disease Surveillance (PDS) of Rinderpest Eradication Campaign. Lot of research work has been initiated during last decade towards disease epidemiology, risk factor recognition, laboratory diagnosis, vaccination and demonstration of control strategies. Although there are ongoing projects working towards the progressive control of the disease in country yet there is need to have a national level control program for PPR. Also there is need to have comprehensive social economic surveys, disease hot spot recognition and identification of role of other species in disease transmission. With combined efforts of local and national authorities and political will, there is high likelihood that this devastating disease can be controlled and eventually eradicated in near future.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.936-941
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• 2005

To achieve rapid developments and ensure competitiveness, cost saving, digital manufacturing is essential in die shops. Digital Manufacturing is a technology to facilitate effective product developments and agile productions by digital environments representing the physical and logical schema and the behavior of real manufacturing system including manufacturing resources, processes and products. For applying digital manufacturing to die shop, engineering information managements of products, manufacturing process and resources are needed. In this paper proposes and implements, PLM approach for achieving engineering collaborations in engineering activities. We suggest detail procedures, some examples and considerations of PPR managements in die shop.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.6 no.5
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• pp.432-438
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• 2005

In this paper, the high precision position control of AC Servo motor for semiconductor equipment is studied. The control system was implemented using TI DSP TMS320F2812 which has 150 MIPS speed for next generation motor control. The controlled 100W PMSM motor has 2,500 ppr optical incremental encoder. The control system has speed controller and current controller to control the motor position. The encoder pulses are divided into 4 times, which has 10,000 ppr and the motor system has the position accuracy of 1/10,000. If the resolution of the encoder is increased, the resolution of the position control will be increased.

• Korea Journal of Hospital Management
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• v.23 no.1
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• pp.87-106
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• 2018

Objective: The objective of this study is to examine the association between process quality of inpatient care and risk-adjusted, thirty-day potentially preventable hospital readmission (PPR) rates. Data Sources/Study Setting: This was an observational cross-sectional study of nonfederal acute-care hospitals located in two states California and Florida, discharging Medicare patients with a principal discharge diagnosis of heart failure, acute myocardial infarction, or pneumonia January through December 31, 2007. Data were obtained from the Healthcare Cost and Utilization Project State Inpatient Database of the Agency for Healthcare Research and Quality, Centers for Medicare and Medicaid Services Hospital Compare database, and the American Hospital Association Annual Survey of Hospitals. Study Design: The dependent variable of this study is condition-specific, risk-adjusted, thirty-day potentially preventable hospital readmission (PPR). 3M's PPR software was utilized to determine whether a readmission was potentially preventable. The independent variable of this study is hospital performance for process quality of inpatient care, measured by hospital adherence to recommended processes of care. We used multivariate hierarchical logistic models, clustered by hospitals, to examine the relationship between condition-specific, risk-adjusted, thirty-day PPR rates and process quality of inpatient care, after taking clinical and socio-demographic characteristics of patients and structural and operational characteristics of hospitals into account. Findings: Better performance on the process quality metrics was associated with better patient outcome (i.e., low thirty-day PPR rates) in pneumonia, but not generally in two cardiovascular conditions (i.e., heart failure and acute myocardial infarction). Practical Implication: Adherence to the process quality metrics currently in use by CMS is associated with risk-adjusted, thirty-day PPR rates for patients with pneumonia, but not with cardiovascular conditions. More evidence-based process quality metrics closely linked to 30-day PPR rates, particularly for cardiovascular conditions, need to be developed to serve as a guideline to reduce potentially preventable readmissions.

• Journal of KIISE:Information Networking
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• v.34 no.2
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• pp.120-133
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• 2007

A multicast tree includes several, possibly a large number of, paths connecting source-receiver pairs, and network failure may disable part of the multicast tree. Reconstruction of the entire multicast tree to recover from a component failure is highly undesirable, because some group members have to suffer service disruptions even though the communication paths to/from them are not affected by the failure. To limit reconfiguration region and to maximize the likelihood of successful reconfiguration, we propose and evaluate a pre-planned reconfiguration policy for QoS multicast sessions. Specifically, we equip a reconfiguration path (RP) with each end-to-end path that connects a source-receiver pair in the multicast tree, and reserve resources in advance along the RPs. Efficient resource-sharing techniques are applied to reduce the amount of resources reserved for RPs but not used in the absence of failures. This way, we prevent uncontrolled competition among different multicast sessions which may simultaneously try to recover from failures. We evaluate the performance of the proposed scheme using simulation on randomly-generated networks. We use the shortest-path routing for QoS multicast sessions, and simulate both source-based and shared multicast trees. The evaluation results indicates that successful pre-planned reconfiguration can be achieved for all group members with reasonable overhead. Our scheme is also shown to adapt well to dynamic changes of group membership.

• CDE review
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• v.15 no.2
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• pp.47-56
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• 2009

• Biomedical Science Letters
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• v.18 no.4
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• pp.428-434
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• 2012

Epilepsy is a chronic neurological disease showing a symptom of repeated seizures without any other physical disorders. Among the diagnostic examination for epilepsy, the electroencephalogram (EEG) has been known as an important test. This study aimed to investigate the EEG with photic stimulation in the pediatric epilepsy patients. They underwent digital sleep and waking EEGs or waking EEGs with photic stimulation. Epilepsy type, seizure history, and season of occurring seizure were analyzed. Epilepsy patients showed more response during the period of photic-on and eye close at the frequency of 10~20 Hz during the EEG activation procedure. Photoparoxysmal response (PPR) was shown in 206 patients out of total 1,551 epilepsy patients. PPR was appeared more frequently during summer and winter seasons, and especially in the patients who had a history of seizure. During the PPR, EEG pattern showed spike (77.18%), theta (9.71%), and spike + theta (13.11%). On the other hand, beta and theta waves were not significantly changed by photic stimulation. However, alpha wave was decreased and delta wave was increased by photic stimulation (P<0.05). These changes may be due to temporarily altered electrophysiological function of the epileptic patient's brain by the photic stimulation. There was no difference in the EEG pattern between the left and right side in the brain. In conclusion, condition of photic-on with closed eyes and frequency of 10~20 Hz during the procedure of EEG activation could be appropriate for obtaining a definite photoparoxysmal response in the electroencephalogram of the pediatric epilepsy patients.

• Journal of Microbiology and Biotechnology
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• v.30 no.4
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• pp.571-582
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• 2020

Quorum sensing (QS)-mediated infections cause severe diseases in human beings. The control of infectious diseases by inhibiting QS using antipathogenic drugs is a promising approach as antibiotics are proving inefficient in treating these diseases. Marine fungal (Pestalotiopsis sydowiana PPR) extract was found to possess effective antipathogenic characteristics. The minimum inhibitory concentration (MIC) of the fungal extract against test pathogen Pseudomonas aeruginosa PAO1 was 1,000 ㎍/ml. Sub-MIC concentrations (250 and 500 ㎍/ml) of fungal extract reduced QS-regulated virulence phenotypes such as the production of pyocyanin, chitinase, protease, elastase, and staphylolytic activity in P. aeruginosa PAO1 by 84.15%, 73.15%, 67.37%, 62.37%, and 33.65%, respectively. Moreover, it also reduced the production of exopolysaccharides (74.99%), rhamnolipids (68.01%), and alginate (54.98%), and inhibited the biofilm formation of the bacteria by 90.54%. In silico analysis revealed that the metabolite of P. sydowiana PPR binds to the bacterial QS receptor proteins (LasR and RhlR) similar to their respective natural signaling molecules. Cyclo(-Leu-Pro) (CLP) and 4-Hydroxyphenylacetamide (4-HPA) were identified as potent bioactive compounds among the metabolites of P. sydowiana PPR using in silico approaches. The MIC values of CLP and 4-HPA against P. aeruginosa PAO1 were determined as 250 and 125 ㎍/ml, respectively. All the antivirulence assays were conducted at sub-MIC concentrations of CLP (125 ㎍/ml) and 4-HPA (62.5 ㎍/ml), which resulted in marked reduction in all the investigated virulence factors. This was further supported by gene expression studies. The findings suggest that the metabolites of P. sydowiana PPR can be employed as promising QS inhibitors that target pathogenic bacteria.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.12
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• pp.50-56
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• 2017

The perimeter structure in high-rise buildings, which plays a major role in resisting lateral forces, is generally formed by the orthogonal placement of the beam and column, but currently various grid patterns are implemented. In a previous study, the adaptability of the $IsoTruss^{(R)}$ grid (ITG) as a perimeter structure was examined. In this study, a method of estimating the required cross sectional area of a member in a preliminary design is proposed. The members of the perimeter structure are placed in three planes, perpendicular (PPR), parallel (PPL) and oblique (POQ) to the lateral loading, and the stiffness of the members in the POQ was taken into account by projecting them onto the PPL or PPR. Three models are established for member size zoning through the height of the building, in order to investigate the effect of the shear and moment in the calculation of the required cross sectional area. To examine the effectiveness of this study, a 64-story building is designed and analyzed. The effect of the member size zoning was examined by comparing the maximum lateral displacement, required steel amount, and axial strength ratio of the columns. Judging from the maximum lateral displacement, which was 97.3% of the allowable limit, the proposed formula seems to be implemental in sizing the members of an ITG structure at the initial stage of member selection.