• Journal of the Institute of Electronics Engineers of Korea CI
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• v.43 no.2 s.308
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• pp.81-92
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• 2006

This paper proposes a robustness watermarking for 3D mesh model based on projection onto convex sets (POCS). After designing the convex sets for robustness and invisibility among some requirements for watermarking system, a 3D-mesh model is projected alternatively onto two constraints convex sets until the convergence condition is satisfied. The robustness convex set are designed for embedding the watermark into the distance distribution of the vertices to robust against the attacks, such as mesh simplification, cropping, rotation, translation, scaling, and vertex randomization. The invisibility convex set are designed for the embedded watermark to be invisible. The decision values and index that the watermark was embedded with are used to extract the watermark without the original model. Experimental results verify that the watermarked mesh model has invisibility and robustness against the attacks, such as translation, scaling, mesh simplification, cropping, and vertex randomization.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.11A
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• pp.870-881
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• 2009

The rapid development of healthcare information management for 3D medical digital library, 3D PACS and 3D medical diagnosis has addressed security issues with medical IT technology. This paper presents multiple 3D medical image data for protection, authentication, indexing and diagnosis information hiding applied to healthcare information management. The proposed scheme based on POCS watermarking embeds the robust watermark for doctor's digital signature and information retrieval indexing key to the distribution of vertex curvedness and embeds the fragile watermark for diagnosis information and authentication reference message to the distance difference of vertex. The multiple embedding process designs three convex sets for robustness, fragileness and invisibility and projects 3D medical image data onto three convex sets alternatively and iteratively. Experimental results confirmed that the proposed scheme has the robustness and fragileness to various 3D geometric and mesh modifiers at once.

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.755-758
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• 2001

In this paper. Ive propose a postprocessing technique based on the theory of projection on convex sets(POCS) to reduce the blocking artifacts in HDTV decoded images. In BDCT of HDTV. the image is divided into a grid of non-overlapped 8 ${\times}$ 8 blocks. and then each block is coded separately. A block which is located one pixel apart from the grid of BDCT will include the boundary of the original 8 ${\times}$ 8 block. If the blocking artifact is Introduced alone the block boundary. this block will have different frequency characteristic from that of the original block. Thus, a comparison of frequency characteristics of these two overlapping blocks can detect the undesired high-frequency components mainly caused by the blocking artifact. By eliminating these undesired high-frequency components adaptively, robust smoothing projection operator can be obtained. Simulation results with real image sequences indicate that the proposed method performs better than conventional algorithms.

• BMB Reports
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• v.53 no.12
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• pp.646-651
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• 2020

Bone resorption is linked to bone formation via temporal and spatial coupling within the remodeling cycle. Several lines of evidence point to the critical role of coupling factors derived from pre-osteoclasts (POCs) during the regulation of bone marrow-derived mesenchymal stem cells (BMMSCs). However, the role of glial cell-derived neurotrophic factor (GDNF) in BMMSCs is not completely understood. Herein, we demonstrate the role of POC-derived GDNF in regulating the migration and osteogenic differentiation of BMMSCs. RNA sequencing revealed GDNF upregulation in POCs compared with monocytes/macrophages. Specifically, BMMSC migration was inhibited by a neutralizing antibody against GDNF in pre-osteoclast-conditioned medium (POC-CM), whereas treatment with a recombinant GDNF enhanced migration and osteogenic differentiation. In addition, POC-CM derived from GDNF knock-downed bone marrow macrophages suppressed BMMSC migration and osteogenic differentiation. SPP86, a small molecule inhibitor, inhibits BMMSC migration and osteogenic differentiation by targeting the receptor tyrosine kinase RET, which is recruited by GDNF into the GFRα1 complex. Overall, this study highlights the role of POC-derived GDNF in BMMSC migration and osteogenic differentiation, suggesting that GDNF regulates bone metabolism.

• Journal of Broadcast Engineering
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• v.6 no.1
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• pp.108-118
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• 2001

In this paper, the conventional deblocing algorithms are compared in each region of the image. Based on the comparison result, we propose a new deblocklng algorithm that can improve subjectives as well as the objective quality. Because the human visual system is mode sensitive to the blocking artifacts in the low frequency re91on, we compare the performance of several deblocking algorithms in 7he low and high frequency region separately. For this purpose we also propose an algorithm for classifying the region into low and high frequency ones. and propose a deblocking algorithm which is applied differently to each region. The result shows that the adaptive LPF method yields the best performance in the low frequency region in terms of both subjective and objective quality. Hence. by applying the adaptive LPF method to the low frequency region, the performance of conventional algorithms can be improved. In the high frequency region. it is observed that the DCT-based POCS algorithm provides the best performance. Hence, by combining the algorithm with the adaptive LPF method, the best objective performance is obtained.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.1
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• pp.166-174
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• 1994

A critical evaluation is made of the spectral bias which occurs in the use of a laser doppler velocimeter(LDV). Two processing algorithms are considered for spectral estimates: the sample and hold interpolation method(SH) and the nonuniform Shannon reconstruction technique(SR). Assessment is made of these for varying data densities $(0.05{\le}d.d.{\le}5)$ and turbulence levels(t.i.=30%, 100%). As an improved version of the spectral estimator, the utility of POCS (the projection onto convex sets) has been tested in the present study. This algorithm is found useful to be in the region when $d.d.{\gep}3.$

• Investigative Magnetic Resonance Imaging
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• v.13 no.1
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• pp.22-30
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• 2009

Purpose : Patient motion during magnetic resonance (MR) imaging is one of the major problems due to its long scan time. Entropy based post-processing motion correction techniques have been shown to correct motion artifact effectively. One of main limitations of these techniques however is its long processing time. In this study, we propose several methods to reduce this long processing time effectively. Materials and Methods : To reduce the long processing time, we used the separability property of two dimensional Fourier transform (2-D FT). Also, a computationally light metric (sum of all image pixel intensity) was used instead of the entropy criterion. Finally, partial Fourier reconstruction, in particular the projection onto convex set (POCS) method, was combined thereby reducing the size of the data which should be processed and corrected. Results : Time savings of each proposed method are presented with different data size of brain images. In vivo data were processed using the proposed method and showed similar image quality. The total processing time was reduced to 15% in two dimensional images and 30% in the three dimensional images. Conclusion : The proposed methods can be useful in reducing image motion artifacts when only post-processing motion correction algorithms are available. The proposed methods can also be combined with parallel imaging technique to further reduce the processing times.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.8
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• pp.1424-1429
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• 2007

This paper presents a simple and reliable one-touch type multi-immunosensing lab-on-a-chip (LOC) detecting antibodies as multi-disease markers using electrochemical method suitable for a portable point-of-care system (POCS). The multi-stacked LOC consists of a PDMS space layer for liquids loading, a PDMS valve layer with 50 im in height for the membrane, a PDMS channel layer for the fluid paths, and a glass layer for multi electrodes. For the disposable immunoassay which needs sequential flow control of sample and buffer liquids according to the designed strategies, reliable and easy-controlled on-chip operation mechanisms without any electric power are necessary. The driving forces of sequential liquids transfer are the capillary attraction force and the pneumatic pressure generated by air bladder push. These passive fluid transport mechanisms are suitable for single-use LOC module. Prior to the application of detection of the antibody as a disease marker, the model experiments were performed with anti-DNP antibody and anti-biotin antibody as target analytes. The flow test results demonstrate that we can control the fluid flow easily by using the capillary stop valve and the PDMS check valves. By the model tests, we confirmed that the proposed LOC is easily applicable to the bioanalytic immunosensors using bioelectrocatalysis.

• Korean Journal of Animal Reproduction
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• v.24 no.4
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• pp.385-394
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• 2000

When porcine primordial germ cells (PGCs) isolated from the genital ridge and placed in culture to establish EG cells, a large proportion of PGCs are lost during the early period of culture. To characterize the in vitro death of porcine PGCs, PGCs were cultured in suspension, and apoptosis analyzed using a fluorescent activated cell sorter-based DNA fragmentation assay. The results from flow cytometric analysis showed an increase in apoptosis in cultured cells. However, the cells isolated from the genital ridges are a mixture of PGCs and somatic cells. To detect apoptotic signals specific from porcine PGCs, quantitative TUNEL assay was performed at different time of culture (0 ∼ 24 h). The proportion of apoptotic porcine PGCs determined by double staining with alkaline phosphatase activity and in situ TUNEL assay increased as the time of culture progressed and continued at least 24 h. These results demonstrate that one of the causes of loss of porcine PGCs in vitro is apoptosis.

• Journal of Genetic Medicine
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• v.8 no.1
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• pp.44-52
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• 2011

Purpose: Cytogenetic analysis of spontaneous abortions (SABs) provides valuable information to establish the causes of fetal loss, information that is essential to provide accurate reproductive and genetic counseling couples. Such analysis also provides information on the frequencies and types of chromosomal abnormalities and associated risks of recurrence. However, there have only been a few reports of chromosomal abnormalities in small samples of SABs in the Korean population. Here, we report the incidence and spectrum of chromosomal abnormalities for cases of 470 SAB in Korea. Material and Methods: Between 2005 and 2010, a total of 470 products of conception (POC) resulting from SABs were submitted to our laboratory for cytogenetic analysis from various medical sites in Korea. The incidences and types of specific chromosomal abnormalities were determined. The abnormalities were distinguished by gestational age at the time of SAB and by maternal age. Results: The frequency of chromosomal abnormalities in POCs was 54.3% (255/470), including 228 (89.3%) numerical and 27 (10.7%: 3 balanced and 24 unbalanced) structural abnormalities. Among the numerical abnormalities, trisomy was predominant (67.0%), followed by monosomy X (12.5%), polyploidy (8.2%), triple X (0.8%), and autosomal monosomy (0.8%). The overall sex ratio (male: female) among the 470 POCs with normal and abnormal karyotypes were 0.58 and 0.65, respectively. Trisomies were identified for each autosome, with the exceptions of 1, 3, and 19. Among the 171 autosomal trisomies, trisomy 16 was the most common (19.9%), followed by trisomy 22 (13.5%), trisomy 21 (12.3 %), trisomy 15 (9.9%), and trisomies 18 and 13 (5.3%). The frequency of chromosomal abnormalities decreased with gestational age and increased with maternal age, but only because of increases in trisomies and complex abnormalities. Conclusions: We have presented a large collection of cytogenetic data for SABs collected during the past 6 years and provided a database for prenatal genetic counseling of parents who have experienced SABs in Korea.