• 스마트미디어저널
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• 제9권4호
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• pp.97-101
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• 2020

본 연구에서는 센서상의 전하량 변화를 통하여 전위차를 측정할 수 있는 수동형 전기장센서를 이용하여 사람의 손동작에 의해 유발되는 신호를 측정 장치의 전원이나 주변 전력선에 의해 센서에 유입되는 잡음(PLN: Power Line Noise)의 고조파 성분을 분석하여 동작신호를 검출하고 추출하는 연구를 수행 한다. 전기장 센서에 유입되는 전력선잡음으로 센서가 사람의 존재, 접근, 동작에 의해 영향 받는 사실을 이용해 PLN의 주성분인 60Hz 고조파 성분의 스펙트럼분석을 수행하여 PLN 신호의 증가 또는 감소를 식별할 수 있고 상대적으로 동작에 민감한 120Hz 성분을 이용한다. FFT를 사용하여 120Hz의 신호성분이 특정 임계값을 통과할 때 신호를 검출하는 방법이다. 동작이 탐지되는 경우 임계값을 기준으로 프레임을 결정한다. 본 연구의 방법을 이용하여 얻은 동작 감지 성공률은 약 90% 수준을 달성하였다. 이렇게 감지된 동작신호로 추출한 프레임의 정확도는 약 85%이다. 수동형 전기장 센서를 이용하여 동작신호를 PLN을 이용하여 동작검출에 이용한 연구사례는 국내외적으로 드문 사례이며, 본 논문에서는 PLN이 상존하는 실내 적용환경에서 유망하게 활용될 수 있다.

• Corrosion Science and Technology
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• 제20권5호
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• pp.242-248
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• 2021

Unforeseen failures of boilers in power plants may affect the continuation of electricity generation. Main failures in boilers are influenced by the tube material, tube position, boiler service temperature and pressure, and chemical composition of the feed water and coal. This investigation was intended to find answers on the causes and mechanism of failure of the fire-side boiler water-wall tubes, due to perforation and corrosion. The tube conformed to the material requirements in terms of its chemical composition and hardness. Microscopic examination showed ferrite and pearlite indicating no changes in its microstructure due to the temperature variation. SEM test showed a single layer and homogenous film density particularly on the area far from perforation. However, layers of corrosion product were formed on the nearby perforation area. EDX showed that there were Na, Ca, S, and O elements on the failed surface. XRD indicated the presence of Fe₂O₃ oxide. The failure mechanism was identified as a result of significant localized wall thinning of the boiler water wall-tube due to oxidation.

• BMB Reports
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• 제38권2호
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• pp.177-181
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• 2005

Effects of common electrophoretic reagents, reducing agents ($\beta$-mercaptoethanol [BME] and DTT), denaturants (SDS and urea), and non-ionic detergent (Triton X-100), on the activity and stability of bovine plasmin (b-pln) and human plasmin (h-pln) were compared. In the presence of 0.1% SDS (w/v), all reagents completely inhibited two plns, whereas SDS (1%) and urea (1 M) denatured plns recovered their activities after removal of SDS by treatment of 2.5% Triton X-100 (v/v). However, reducing agents (0.1 M of BME and DTT) treated plns did not restore their activities. Based on a fibrin zymogram gel, five (from b-pln) and four (from h-pln) active fragments were resolved. Two plns exhibited unusual stability in concentrated SDS and Triton X-100 (final 10%) and urea (final 6 M) solutions. Two bands, heavy chain-2 (HC-2) and cleaved heavy chain-2 (CHC-2), of b-pln were completely inhibited in 0.5% SDS or 3 M urea, whereas no significant difference was found in h-pln. Interestingly, 50 kDa (cleaved heavy chain-1, CHC-1) of b-pln and two fragments, 26 kDa (light chain, LC) and 29 kDa (microplasmin, MP), of h-pln were increased by SDS in a concentration dependent manner. We also found that the inhibition of SDS against both plns was reversible.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1675-1679
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• 2014

Objectives: MicroRNAs (miRNAs) are important regulators of many physiological and pathological processes, including tumorigenesis and metastasis. In this study, we sought to determine the underlying molecular mechanisms of metastatic cervical carcinoma by performing miRNA profiling. Methods: Tissue samples were collected from ten cervical squamous cancer patients who underwent hysterectomy and pelvic lymph node (PLN) dissection in our hospital, including four PLN-positive (metastatic) cases and six PLN-negative (non-metastatic) cases. A miRNA microarray platform with 1223 probes was used to determine the miRNA expression profiles of these two tissue types and case groups. MiRNAs having at least 4-fold differential expression between PLN-positive and PLN-negative cervical cancer tissues were bioinformatically analyzed for target gene prediction. MiRNAs with tumor-associated target genes were validated by quantitative reverse transcription-polymerase chain reaction (RT-PCR). Results: Thirty-nine miRNAs were differentially expressed (>4-fold) between the PLN-positive and PLN-negative groups, of which, 22 were up-regulated and 17 were down-regulated. Sixty-nine percent of the miRNAs (27/39) had tumor-associated target genes, and the expression levels of six of those (miR-126, miR-96, miR-144, miR-657, miR-490-5p, and miR-323-3p) were confirmed by quantitative (q)RT-PCR. Conclusions: Six MiRNAs with predicted tumor-associated target genes encoding proteins that are known to be involved in cell adhesion, cytoskeletal remodeling, cell proliferation, cell migration, and apoptosis were identified. These findings suggest that a panel of miRNAs may regulate multiple and various steps of the metastasis cascade by targeting metastasis-associated genes. Since these six miRNAs are predicted to target tumor-associated genes, it is likely that they contribute to the metastatic potential of cervical cancer and may aid in prognosis or molecular therapy.

• 대한한방내과학회지
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• 제29권3호
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• pp.742-751
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• 2008

Objective: The purpose of this study was to evaluate the effect of Samjawhadam-jeon (SJHDJ; 三子化痰煎) on immune cells in OVA-induced asthmatic mice. Material and Methods : C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (four times a week) for asthma induction. Two experimental groups were treated with different concentrations of SJHDJ group (400 mg/kg) extracts and cyclosporin A (10 mg/kg) for the latter 8 weeks. At the end of the experiment, the mouse lung. peripheral lymph node (PLN) and spleen were removed and immune cells were analyzed by flow cytometer. Results : Lung weight, total cells in lung, PLN, and spleen of the SJHDJ group decreased significantly compared with that of the control group. Number of $CD3e^+/CD69^+$, $CD3e^+/DX5^+$ cells in lung, PLN and spleen, number of $CD3^+$ cells in PLN and spleen, number of $CD3e^-/CCR3^+$ cells in lung and PLN, and number of $B220^+/IgE^+$ cells in PLN of the SJHDJ group decreased compared with that of the control group. Number of $CD4^+/CD25^+$ cells in PLN and spleen of the SJHDJ group increased compared with that of the control group. Conclusion : These results demonstrate that SJHDJ will be a desirable alternative therapy for allergic asthma by inhibiting the expression of immune cells.

• 스마트미디어저널
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• 제4권1호
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• pp.33-38
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• 2015

분 논문에서는 전위계 센서를 이용한 비접촉식 동작인식거리를 확장하기 위해 1K Hz 이하의 극저주파 EMI를 제거하는 기법과 제스처 동작 시작점 추출을 위한 PLN(Power Line Noice)을 이용하는 기법을 제시한다. 스마트기기 상에 장착된 전위계차 센서 주변에서 발생하는 극저주파대역의 전기장의 세기를 측정하여 효율적인 센서의 배치를 통해 EMI를 제거하는 동시에 60Hz 대역의 PLN 잡음은 오히려 동작 시작점 검출을 위하여 이용하는 기법을 제안한다. 이 후, 접지를 통해 스마트 기기 및 센서의 회로에서 발생하는 전원선 잡음을 제거하고, 스마트 TV와 센서의 사이를 차폐시킴으로써 스마트 기기에서 발생하는 전기적 잡음을 제거한다. 마지막으로 필터기법을 이용하여 남아있는 미세 잡음을 제거한다. 전위계차 센서를 스마트기기의 비접촉식 원격제어에 활용하기 위한 극저주파대역 EMI의 효과적인 제거 기법 및 성능을 분석하였으며, 또한 전위계차 센서의 비접촉식 응용에 난제중 하나인 동작시작점 검출을 위한 효과적인 방법을 제시하여 제스처 인식거리를 실제 응용가능한 3m 이상으로 확장할 수 있음을 보였다.

• 동력기계공학회지
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• 제1권1호
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• pp.42-51
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• 1997

In this study, in order to investigate the influence of cam profile on the injection rate, the characteristics of injection in PLN (pump - line - nozzle) diesel injection system were simulated. Six types of the profile of fuel cam were used for simulation. The maximum injection pressure and maximum injection rate of initial and end phase were analyzed to demonstrate the characteristics of injection. The mathematical model of the injection system and the computation results were verified by experimental results. Simulation results showed that the maximum injection pressure, maximum injection rate, injection quantity and pressure drop in the end phase were proportional to the velocity of fuel cam during the effective stroke.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제36권3호
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• pp.417-438
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• 2022

본 연구의 목적은 개별화 맞춤형 수학 학습을 지원하는 AI 기반 플랫폼 활용 시 고려해야 할 교수·학습에 관한 시사점을 제안하는 것이다. 이를 위해 국내·외 공교육에서 활용되고 있는 플랫폼 5개(똑똑!수학탐험대, 노리AI스쿨수학, 칸 아카데미, MATHia, CENTURY)를 분석대상으로 선정하여, AI 기반 수학교육 플랫폼이 개별화 맞춤형 학습을 지원하기 위한 세 가지 요소(PLP, PLN, PLE)를 어떻게 반영하고 있는지를 분석하였다. 그 결과, 각 플랫폼에서 구현하고 있는 PLP, PLN, PLE의 특징은 다양했지만, PLP와 PLN을 바탕으로 학습자가 자율적으로 학습에 대한 의사결정을 내릴 수 있는 PLE를 형성할 수 있도록 설계된 것으로 분석되었다. 본 연구의 의의는 AI 기반 수학교육 플랫폼을 활용하는 개별화 맞춤형 수학 학습에 대한 이해도와 실천 가능성을 높였다는 데에서 찾을 수 있다.

• 대한한의학회지
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• 제29권2호
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• pp.7-20
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• 2008

Objectives: The purpose of this study wasto examine the effects of Kamijihwang-tang (KJHT) extracts on immune cells and cytokines in ovalbumin (OVA)-induced asthmatic mice. Methods: C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (four times a week) for asthma induction. Two experimental groups were treated with different concentrations of KJHT (400 mg/kg and 200 mg/kg) extracts and cyclosporine A (10 mg/kg) for the later 8 weeks. At the end of the experiment, the mice lung, PLN and spleen were removed and immune cells were analyzed by flow cytometer, IL-5, IL-13, eotaxin-2, $TNF-{\alpha}$ were analyzed by real-time PCR, serum histamine was analyzed by ELISA kit. Results: $CD3^+$, $CD3e^-/CCR3^+$, $CD3e^+/CD69^+$, $CD4^+/CD25^+$, $B220^+/IgE^+$, and $CD3e^+/DX5^+$ cells in lung, PLN, and spleen of the KJHT group (400 mg/kg) decreased compared with that of the control group. $CD3e^+/CD69^+$, $CD4^+/CD25^+$, and $CD3e^+/DX5^+$ cells in lung, PLN, and spleen of the KJHT group (200 mg/kg), CD3+, $CD3e^-/CCR3^+$ cells in lung and PLN of the KJHT group (200 mg/kg) and $B220^+/IgE^+$ cells in lung and spleen of the KJHT group (200 mg/kg) decreased compared with that of the control group. mRNA expression of IL-5, IL-13, eotaxin-2, and $TNF-{\alpha}$ in lung tissue of the KJHT groups (400 mg/kg and 200 mg/kg) decreased compared with that of the control group. Histamine in serum of the KJHT group (400 mg/kg) decreased compared with that of the control group. Conclusions: These results suggest that KJHT can be utilized effectively in treating asthma because it significantly reduces inflammatory cells and cytokines.

• 동의생리병리학회지
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• 제21권2호
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• pp.438-443
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• 2007

The purpose of this research is to examine the effects of Kamijihwang-tang(KJHT) on CD+4 T cells and CD8+ T cell ovalbumin (OVA)-induced asthmatic mice. C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (four a week) for asthma induction. Two experimental groups were treated with different concentrations of KJHT (400 mg/kg and 200 mg/kg) extract and cyclosporine A (10 mg/kg) for the later 8 weeks. At the end of the experiment, the mice lung, peripheral lymph node (PLN), and spleen were removed and CD4+ T cells and CD8 + T cells for analyzed by flow cytometer. Number of CD4+ T cells in lung, PLN, spleen of the KJHT group (400 mg/kg) were significantly decreased compared with that of control group. Number of CD8+ T cells in lung, PLN, spleen of the KJHT group (200 mg/kg) were significantly decreased compared with that of control group. The results of this study suggest that KJHT alleviated asthmatic hyperactivity through CD4+ and CD8+ T cells. Further study of relative cytokines is expected.