• Smart Media Journal
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• v.9 no.4
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• pp.97-101
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• 2020

Using passive electric field sensor which operates in non-contact mode, we can measure the electric potential induced from the change of electric charges on a sensor caused by the movement of human body or hands. In this study, we propose a new method, which utilizes PLN induced to the sensor around the moving object, to detect one's hand movement and extract gesture frames from the detected signals. Signals from the EPS sensors include a large amount of power line noise usually existing in the places such as rooms or buildings. Using the fact that the PLN is shielded in part by human access to the sensor, signals caused by motion or hand movement are detected. PLN consists mainly of signals with frequency of 60 Hz and its harmonics. In our proposed method, signals only 120 Hz component in frequency domain are chosen selectively and exclusively utilized for detection of hand movement. We use FFT to measure a spectral-separated frequency signal. The signals obtained from sensors in this way are continued to be compared with the threshold preset in advance. Once motion signals are detected passing throng the threshold, we determine the motion frame based on period between the first threshold passing time and the last one. The motion detection rate of our proposed method was about 90% while the correct frame extraction rate was about 85%. The method like our method, which use PLN signal in order to extract useful data about motion movement from non-contact mode EPS sensors, has been rarely reported or published in recent. This research results can be expected to be useful especially in circumstance of having surrounding PLN.

• Corrosion Science and Technology
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• v.20 no.5
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• pp.242-248
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• 2021

Unforeseen failures of boilers in power plants may affect the continuation of electricity generation. Main failures in boilers are influenced by the tube material, tube position, boiler service temperature and pressure, and chemical composition of the feed water and coal. This investigation was intended to find answers on the causes and mechanism of failure of the fire-side boiler water-wall tubes, due to perforation and corrosion. The tube conformed to the material requirements in terms of its chemical composition and hardness. Microscopic examination showed ferrite and pearlite indicating no changes in its microstructure due to the temperature variation. SEM test showed a single layer and homogenous film density particularly on the area far from perforation. However, layers of corrosion product were formed on the nearby perforation area. EDX showed that there were Na, Ca, S, and O elements on the failed surface. XRD indicated the presence of Fe₂O₃ oxide. The failure mechanism was identified as a result of significant localized wall thinning of the boiler water wall-tube due to oxidation.

• BMB Reports
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• v.38 no.2
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• pp.177-181
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• 2005

Effects of common electrophoretic reagents, reducing agents ($\beta$-mercaptoethanol [BME] and DTT), denaturants (SDS and urea), and non-ionic detergent (Triton X-100), on the activity and stability of bovine plasmin (b-pln) and human plasmin (h-pln) were compared. In the presence of 0.1% SDS (w/v), all reagents completely inhibited two plns, whereas SDS (1%) and urea (1 M) denatured plns recovered their activities after removal of SDS by treatment of 2.5% Triton X-100 (v/v). However, reducing agents (0.1 M of BME and DTT) treated plns did not restore their activities. Based on a fibrin zymogram gel, five (from b-pln) and four (from h-pln) active fragments were resolved. Two plns exhibited unusual stability in concentrated SDS and Triton X-100 (final 10%) and urea (final 6 M) solutions. Two bands, heavy chain-2 (HC-2) and cleaved heavy chain-2 (CHC-2), of b-pln were completely inhibited in 0.5% SDS or 3 M urea, whereas no significant difference was found in h-pln. Interestingly, 50 kDa (cleaved heavy chain-1, CHC-1) of b-pln and two fragments, 26 kDa (light chain, LC) and 29 kDa (microplasmin, MP), of h-pln were increased by SDS in a concentration dependent manner. We also found that the inhibition of SDS against both plns was reversible.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1675-1679
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• 2014

Objectives: MicroRNAs (miRNAs) are important regulators of many physiological and pathological processes, including tumorigenesis and metastasis. In this study, we sought to determine the underlying molecular mechanisms of metastatic cervical carcinoma by performing miRNA profiling. Methods: Tissue samples were collected from ten cervical squamous cancer patients who underwent hysterectomy and pelvic lymph node (PLN) dissection in our hospital, including four PLN-positive (metastatic) cases and six PLN-negative (non-metastatic) cases. A miRNA microarray platform with 1223 probes was used to determine the miRNA expression profiles of these two tissue types and case groups. MiRNAs having at least 4-fold differential expression between PLN-positive and PLN-negative cervical cancer tissues were bioinformatically analyzed for target gene prediction. MiRNAs with tumor-associated target genes were validated by quantitative reverse transcription-polymerase chain reaction (RT-PCR). Results: Thirty-nine miRNAs were differentially expressed (>4-fold) between the PLN-positive and PLN-negative groups, of which, 22 were up-regulated and 17 were down-regulated. Sixty-nine percent of the miRNAs (27/39) had tumor-associated target genes, and the expression levels of six of those (miR-126, miR-96, miR-144, miR-657, miR-490-5p, and miR-323-3p) were confirmed by quantitative (q)RT-PCR. Conclusions: Six MiRNAs with predicted tumor-associated target genes encoding proteins that are known to be involved in cell adhesion, cytoskeletal remodeling, cell proliferation, cell migration, and apoptosis were identified. These findings suggest that a panel of miRNAs may regulate multiple and various steps of the metastasis cascade by targeting metastasis-associated genes. Since these six miRNAs are predicted to target tumor-associated genes, it is likely that they contribute to the metastatic potential of cervical cancer and may aid in prognosis or molecular therapy.

• The Journal of Internal Korean Medicine
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• v.29 no.3
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• pp.742-751
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• 2008

Objective: The purpose of this study was to evaluate the effect of Samjawhadam-jeon (SJHDJ; 三子化痰煎) on immune cells in OVA-induced asthmatic mice. Material and Methods : C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (four times a week) for asthma induction. Two experimental groups were treated with different concentrations of SJHDJ group (400 mg/kg) extracts and cyclosporin A (10 mg/kg) for the latter 8 weeks. At the end of the experiment, the mouse lung. peripheral lymph node (PLN) and spleen were removed and immune cells were analyzed by flow cytometer. Results : Lung weight, total cells in lung, PLN, and spleen of the SJHDJ group decreased significantly compared with that of the control group. Number of $CD3e^+/CD69^+$, $CD3e^+/DX5^+$ cells in lung, PLN and spleen, number of $CD3^+$ cells in PLN and spleen, number of $CD3e^-/CCR3^+$ cells in lung and PLN, and number of $B220^+/IgE^+$ cells in PLN of the SJHDJ group decreased compared with that of the control group. Number of $CD4^+/CD25^+$ cells in PLN and spleen of the SJHDJ group increased compared with that of the control group. Conclusion : These results demonstrate that SJHDJ will be a desirable alternative therapy for allergic asthma by inhibiting the expression of immune cells.

• Smart Media Journal
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• v.4 no.1
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• pp.33-38
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• 2015

In this paper, we propose the methods not only to eliminate ELF(Extremely Low Frequency) EMI(Electro-Magnetic Interference) noice for extending recognition distance, but also to utilize the the PLN for detecting starting instance of a hand gesture using electric potential sensor. First, we measure strength of electric field generated in the smart devices such as TV and phone, and minimize EMI through efficient arrangement of the sensors. Meanwhile, we utilize the 60 Hz PLN to extract the starting point of hand gesture. Thereafter, we eliminate the PLN generated in the smart device and circuit of sensors. And then, we shield the sensors from an electric noise generated from devices. Finally, through analyzing the frequency components according to the gesture of target, we use the low pass filter and the Kalman filter for elimination of remaining electric noise. We analyze and evaluate the proposed ELF-band EMI eliminating method for non-contact remote sensing of the EPS(Electric Potential Sensor). Combined with a detecting technique of gesture starting point, the recognition distance for gestures has been proven to be extended to more than 3m, which is critical for real application.

• Journal of Power System Engineering
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• v.1 no.1
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• pp.42-51
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• 1997

In this study, in order to investigate the influence of cam profile on the injection rate, the characteristics of injection in PLN (pump - line - nozzle) diesel injection system were simulated. Six types of the profile of fuel cam were used for simulation. The maximum injection pressure and maximum injection rate of initial and end phase were analyzed to demonstrate the characteristics of injection. The mathematical model of the injection system and the computation results were verified by experimental results. Simulation results showed that the maximum injection pressure, maximum injection rate, injection quantity and pressure drop in the end phase were proportional to the velocity of fuel cam during the effective stroke.

• Communications of Mathematical Education
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• v.36 no.3
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• pp.417-438
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• 2022

The purpose of this study is to suggest implications for mathematics teaching and learning when using AI-based educational platforms that support personalized mathematics learning. To this end, we selected five platforms(Knock-knock! Math Expedition, knowre, Khan Academy, MATHia, CENTURY) and analyzed how the AI-based educational platforms for mathematics reflect the three elements(PLP, PLN, PLE) to support personalized learning. The results of this study showed that although the characteristics of PLP, PLN, and PLE implemented on each platform varied, they were designed to form PLEs that allow learners to make their autonomous decisions about learning based on PLP and PLN. The significance of this study can be found in that it has improved the understanding and practicability of personalized mathematics learning with the AI-based educational platforms.

• The Journal of Korean Medicine
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• v.29 no.2
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• pp.7-20
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• 2008

Objectives: The purpose of this study wasto examine the effects of Kamijihwang-tang (KJHT) extracts on immune cells and cytokines in ovalbumin (OVA)-induced asthmatic mice. Methods: C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (four times a week) for asthma induction. Two experimental groups were treated with different concentrations of KJHT (400 mg/kg and 200 mg/kg) extracts and cyclosporine A (10 mg/kg) for the later 8 weeks. At the end of the experiment, the mice lung, PLN and spleen were removed and immune cells were analyzed by flow cytometer, IL-5, IL-13, eotaxin-2, $TNF-{\alpha}$ were analyzed by real-time PCR, serum histamine was analyzed by ELISA kit. Results: $CD3^+$, $CD3e^-/CCR3^+$, $CD3e^+/CD69^+$, $CD4^+/CD25^+$, $B220^+/IgE^+$, and $CD3e^+/DX5^+$ cells in lung, PLN, and spleen of the KJHT group (400 mg/kg) decreased compared with that of the control group. $CD3e^+/CD69^+$, $CD4^+/CD25^+$, and $CD3e^+/DX5^+$ cells in lung, PLN, and spleen of the KJHT group (200 mg/kg), CD3+, $CD3e^-/CCR3^+$ cells in lung and PLN of the KJHT group (200 mg/kg) and $B220^+/IgE^+$ cells in lung and spleen of the KJHT group (200 mg/kg) decreased compared with that of the control group. mRNA expression of IL-5, IL-13, eotaxin-2, and $TNF-{\alpha}$ in lung tissue of the KJHT groups (400 mg/kg and 200 mg/kg) decreased compared with that of the control group. Histamine in serum of the KJHT group (400 mg/kg) decreased compared with that of the control group. Conclusions: These results suggest that KJHT can be utilized effectively in treating asthma because it significantly reduces inflammatory cells and cytokines.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.2
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• pp.438-443
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• 2007

The purpose of this research is to examine the effects of Kamijihwang-tang(KJHT) on CD+4 T cells and CD8+ T cell ovalbumin (OVA)-induced asthmatic mice. C57BL/6 mice were injected, inhaled and sprayed with OVA for 12 weeks (four a week) for asthma induction. Two experimental groups were treated with different concentrations of KJHT (400 mg/kg and 200 mg/kg) extract and cyclosporine A (10 mg/kg) for the later 8 weeks. At the end of the experiment, the mice lung, peripheral lymph node (PLN), and spleen were removed and CD4+ T cells and CD8 + T cells for analyzed by flow cytometer. Number of CD4+ T cells in lung, PLN, spleen of the KJHT group (400 mg/kg) were significantly decreased compared with that of control group. Number of CD8+ T cells in lung, PLN, spleen of the KJHT group (200 mg/kg) were significantly decreased compared with that of control group. The results of this study suggest that KJHT alleviated asthmatic hyperactivity through CD4+ and CD8+ T cells. Further study of relative cytokines is expected.