• 제목/요약/키워드: PL.

검색결과 2,988건 처리시간 0.025초

단백질 분해효소억제제를 이용한 담배의 품질평가 (Evaluation of Cigarette Quality by Use of ??1-Protease Inhibitor)

  • 손형옥;임흥빈;이영구;이동욱;김용태
    • 한국연초학회지
    • /
    • 제13권2호
    • /
    • pp.27-33
    • /
    • 1991
  • Current studies indicated that emphysema in smokers might be due, in part, to the local suppression of G, -protease inhibitor(u, -Pl) in lung by reactive oxygen species in cigarette smoke or smoke-activated lung neutrophiles. In the present works, we examined the possibility that a measure which inactivated $\alpha$l-Pl by cigarette smoke could be an alternative method to evaluate the cigarette quality, In order to determine the inactivation of $\alpha$1, -Pl, trypsin inhibitory capacity(TIC) was assayed. A rapid loss of $\alpha$1, -Pl activity occurred when $\alpha$1-Pl solutions was exposed the gas phase or total particulate matter(TPM) obtained from various brands. The inactivation of $\alpha$1-Pl by gas phase was dependent upon the number of puffs and the age of the smoke. However, that by TPM was rather decreased since 2 puffs and also showed no more change over 24hrs after exposing. Inactivation of $\alpha$1-Pl determined by our suggested method(5 puffs, 24hours of aging after exposing) using various commercial cigarettes exhibited that high tar brands has inactivated it more strongly than low tar cigarettes. But the ability of some brands to inactivate $\alpha$1-Pl does not correlate with the content of tar or nicotine. These results so여esc that the degree of $\alpha$1-Pl inactivation by cigarette smoke may be a useful index for the evaluation of cigarette quality and that it should be also contribute to the manufacture of less hazardous cigarettes.

  • PDF

인삼잎의 지질조성에 주는 재배온도의 영향 (Effect of Growth Temperature on the Composition of Leaf Lipids in Panax ginseng)

  • 박훈;조병구
    • Journal of Ginseng Research
    • /
    • 제11권1호
    • /
    • pp.39-45
    • /
    • 1987
  • Panu ginseng (6 Year old) was grown $17^{\circ}C$/$15^{\circ}C$ and $27^{\circ}C$ day/$23^{\circ}C$ night in the light room of phytotron for 84 days. The composition of neutral lipid(NL), glycolipid(GL), phospholipid(PL) and fatty acids were investigated in leaves. The contents of NL and GL were higher in $25^{\circ}C$ while PL was lower. Similarity (simple correlation) of lipid composition between $16^{\circ}C$ and $25^{\circ}C$ was not significant for PL and GL but significant for NL(p = 0.001), indicating that PL and GL were important factors in the mostability. Similarity of fatty acid composition between growth temperatures was highly significant (p = 0.001) for all three lipids, while similarity between lipids was significant between NL and PL (p=0.01) and NL and GL (p=0.05), but nonsignificant between GL and PL at $16^{\circ}C$. .In NL digalactosyldiacylglycerol (3->$7^{\circ}$) increased but monogalactosyldiacylglycerol (10%) did not change at $25^{\circ}C$. In PL phosphatidic acid (22 -> 4%) and phosphatidylinositol (18 -> 5%) decreased but phosphatidyl ethanolamine (12->l6%) increased at $25^{\circ}C$. Percent unsaturated acid slightly decreased in NL and PL but greatly increased in GL at $25^{\circ}C$. Percent unsaturated bond slightly decreased in NL but did not change in PL and GL.

  • PDF

Effect of Enterococcus faecalis strain PL9003 on Adherence and Growth of Helicobacter pylori

  • Nam, Hye-Ran;Ha, Mi-Sun;Lee, En-Jung;Lee, Yeon-Hee
    • Journal of Microbiology and Biotechnology
    • /
    • 제12권5호
    • /
    • pp.746-752
    • /
    • 2002
  • The purpose of the present study was to examine the antagonistic activities of Enterococcus faecalis strain PL9003 (PL9003) on Helicobacter pylori. This strain was isolated from infant feces and found to inhibit both the growth of H. pylori and its in vitro adherence to the human gastric cell line MKN-45. The binding of PL9003 to MKN-45 was observed under a light microscope after Cram staining and under a scanning electron microscope. When detected with an FITC-conjugate antibody, both viable and nonviable PL9003 were found to decrease the number of H. pylori bound to MKN-45. When detected by an enzyme-linked immunoabsorbent assay, about 70% of the H. pylori bound on MKN-45 disappeared with the four-1314 addition of viable or nonviable PL9003. The spent culture supernatant (SCS) of PL9003 also decreased the viability of H pylori even after neutralization and pepsin treatment. The above results suggest that PL9003 has a potential as a new probiotic for the stomach.

InAs/GaAs 양자점의 발광특성에 대한 InGaAs 캡층의 영향 (Influence of InGaAs Capping Layers on the Properties of InAs/GaAs Quantum Dots)

  • 권세라;류미이;송진동
    • 한국진공학회지
    • /
    • 제21권6호
    • /
    • pp.342-347
    • /
    • 2012
  • Migration-enhanced molecular beam epitaxy법을 이용하여 GaAs 기판에 성장한 InAs 양자점(quantum dots: QDs)의 광학적 특성을 PL (photoluminescence)과 time-resolved PL을 이용하여 분석하였다. 시료 온도, 여기 광의 세기, 발광 파장에 따른 InAs/GaAs QDs (QD1)과 $In_{0.15}Ga_{0.85}As$ 캡층을 성장한 InAs/GaAs QDs (QD2)의 발광특성을 연구하였다. QD2의 PL 피크는 QD1의 PL 피크보다 장파장에서 나타났으며, 이것은 InGaAs 캡층의 In이 InAs 양자점으로 확산되어 양자점의 크기가 증가한 것으로 설명된다. 10 K에서 측정한 QD1과 QD2의 PL 피크인 1,117 nm와 1,197 nm에서 PL 소멸시간은 각각 1.12 ns와 1.00 ns이고, 발광파장에 따른 PL 소멸시간은 PL 피크 근처에서 거의 일정하게 나타났다. QD2의 PL 소멸시간이 QD1보다 짧은 것은 QD2의 양자점이 커서 파동함수 중첩이 향상되어 캐리어 재결합이 증가한 때문으로 설명된다.

다층 성장한 InAs/InAlGaAs 양자점의 광학적 특성 (Optical Characteristics of Multi-Stacked InAs/InAlGaAs Quantum Dots)

  • 오재원;권세라;류미이;조병구;김진수
    • 한국진공학회지
    • /
    • 제20권6호
    • /
    • pp.442-448
    • /
    • 2011
  • 자발형성법으로 InP (001) 기판에 성장한 InAs/InAlGaAs 양자점(QDs, quantum dots)의 광학적 특성을 PL (photoluminescence)과 TRPL (time-resolved PL)을 이용하여 분석하였다. InAs 양자점 시료는 single layer InAs/InAlGaAs QDs (QD1)과 7-stacked InAs/InAlGaAs QDs (QD2)를 사용하였다. 저온(10 K)에서 QD1과 QD2 모두 1,320 nm에서 PL 피크가 나타났으며, 온도를 300 K까지 증가하였을 때 각각 178 nm와 264 nm의 적색편이(red-shift)를 보였다. QD1의 PL 소멸시간은 PL 피크인 1,320 nm에서 1.49 ns이고, PL 피크를 중심으로 장파장과 단파장으로 이동하면서 점차 짧아졌다. 그러나 QD2의 PL 소멸시간은 발광파장이 1,130 nm에서 1,600 nm까지 증가할 때 1.83 ns에서 1.22 ns로 점진적으로 짧아졌다. 이러한 QD2의 PL과 TRPL 결과는 평균 양자점의 크기가 InAs/InAlGaAs 층이 증가함에 따라 점차 증가하기 때문으로 single layer인 QD1에 비해 양자점 크기의 변화가 더 크기 때문으로 설명된다.

제조물책임법에 대응하기 위한 시스템 구축에 관한 연구 -중소기업을 중심으로- (A Study on System Construction to the Product Liability Law-with focus on a small & medium business)

  • 한민석
    • 한국산학기술학회논문지
    • /
    • 제18권6호
    • /
    • pp.596-608
    • /
    • 2017
  • 2002년 제조물책임법(PL)을 시행하여 소비자가 제조물을 생산하고 판매하는 기업에 대하여 제품의 결함에 따른 손해배상을 청구할 수 있도록 하는 제도적 장치를 마련하였다. 그러나 최근 가습기 살균제 사건 등으로 인해 기업의 제조물책임 강화와 소비자 피해구제를 위한 집단소송제도, 징벌적배상제 도입을 위하여 제조물책임법 개정안 등 현재, 12여건의 관련 법안이 국회에 발의되어 있으나 정작 법안의 이해 당사자인 중소기업의 62.6%는 이에 대해 잘 알고 있지 못한 것으로 나타났다고 하고 있다. 많은 기업들이 PL 방어대책(Product Liability Defense : PLD)으로 문서작성 보관의 적정화, 관련업자와의 책임관계의 명확화, PL 보험의 가입 또는 배상자금의 확보 등으로 대비하고 있으나 이와 같은 대비책은 제품의 설계와 제품의 안전성을 고려한 부분에 대하여 한계점을 느끼게 한다. 이에 본 연구는 먼저 PL의 명확한 개념과 대응방안에 대해 살펴보고 PL 시스템과 개별 경영시스템 간의 관련성을 파악하고 제조물책임법에 대비한 PL 대응시스템을 기업의 개별경영시스템에 통합하고 보다 제품의 안전에 중점을 둔 개별경영시스템 모델을 제시하고자한다. 이 같은 연구목적에 따른 결과는 중소기업의 PL법 대응을 위한 합리적 대응방안으로 평가 받을 것으로 기대된다.

Construction of a Genetic System for Streptomyces albulus PD-1 and Improving Poly(ε-ʟ-lysine) Production Through Expression of Vitreoscilla Hemoglobin

  • Xu, Zhaoxian;Cao, Changhong;Sun, Zhuzhen;Li, Sha;Xu, Zheng;Feng, Xiaohai;Xu, Hong
    • Journal of Microbiology and Biotechnology
    • /
    • 제25권11호
    • /
    • pp.1819-1826
    • /
    • 2015
  • Poly(ε-ʟ-lysine) (ε-PL) is a novel bioactive polymer secreted by filamentous bacteria. Owing to lack of a genetic system for most ε-PL-producing strains, very little research on enhancing ε-PL biosynthesis by genetic manipulation has been reported. In this study, an effective genetic system was established via intergeneric conjugal transfer for Streptomyces albulus PD-1, a famous ε-PL-producing strain. Using the established genetic system, the Vitreoscilla hemoglobin (VHb) gene was integrated into the chromosome of S. albulus PD-1 to alleviate oxygen limitation and to enhance the biosynthesis of ε-PL in submerged fermentation. Ultimately, the production of ε-PL increased from 22.7 g/l to 34.2 g/l after fed-batch culture in a 5 L bioreactor. Determination of the oxygen uptake rate, transcriptional level of ε-PL synthetase gene, and ATP level unveiled that the expression of VHb in S. albulus PD-1 enhanced ε-PL biosynthesis by improving respiration and ATP supply. To the best of our knowledge, this is the first report on enhancing ε-PL production by chromosomal integration of the VHb gene in an ε-PL-producing strain, and it will open a new avenue for ε-PL production.

수용가 전기설비 관리자의 PL인식 및 설비사고사례에 관한 실태연구 (The Study on the Actual Condition about Facility Accident Case and PL Recognition of the Safety Manager in Electric Installation for Private Use)

  • 김영석;송길목;정종욱;정진수;김선구;이준
    • 한국조명전기설비학회:학술대회논문집
    • /
    • 한국조명전기설비학회 2008년도 춘계학술대회 논문집
    • /
    • pp.309-312
    • /
    • 2008
  • In this paper, we investigated electric safety manager's PL recognition and accident occurrence of electric power facilities(power cable, transformer, circuit breaker) in electric installation for private use. The target of questionnaire survey is 450 electric installations for private use, 154 responded the questionnaire among these and it occupied 35.8%. Most of receiving voltage were 22.900kV. The questionnaire survey says that 58% of electric safety manager knew well about PL contents and 42% of them did not recognize about PL contents, About the PL application of electrical facility accidents, 82.4% of them must applied PL law, 5.8% of them did not need the PL law. Reason of PL application occupied 64% for stability of electrical facility and product, 19% for prevention of same accident. The accident of transformer occupied most and the power cable accident were much next. The questionnaire survey results, electric safety managers are interested in PL content. thev expected necessity of PL application about electrical accident strongly.

  • PDF

치환리터럴에 의한 Quaternary Galois Field Sum-Of-Product(QGFSOP)형 1-변수 함수의 합성과 실현 (Syntheses and realization of Quaternary Galois Field Sum-Of-Product(QGFSOP) expressed 1-variable functions Permutational Literals)

  • 박동영;김백기;성현경
    • 한국항행학회논문지
    • /
    • 제14권5호
    • /
    • pp.710-717
    • /
    • 2010
  • Quaternary 논리에서 생성 가능한 1-qudit(1-variable quantum digit) 함수는 총 256개가 존재하지만 이들 중에서 가장 유용한 것은 "0,1,2,3"의 치환에 의해 $Ax^C$+D(GF4)형의 QGFSOP 표현이 가능한 24개이다. 본 논문에서는 24개 1-qudit 함수들의 $Ax^C$+D(GF4) 연산에서 피연산자인 피승수 A와 피기수 D를 다단 종속된 치환리터럴의 제어인자로 사용하는 치환리터럴(Permutational Literals, PL) 표현과 QPL(Quaternary PL) gate를 제안하였다. 그리고 상호치환 'ab', 가산 '+D', 그리고 승산 'xA'과 같은 세 개의 PL 연산자를 사용하여 QGFSOP 표현된 24개 (1-qudit) 함수를 합성하기 위한 PL 합성법을 제안하였다. 끝으로 PL 합성법을 실현하기 위한 $Ax^C$+D(GF4) 구조와 연산회로 및 CMOS 실현 방법을 제시하였다.

온도에 따른 실리콘 나노결정 PL 특성 (PL characteristics of silicon-nanocrystals as a function of temperature)

  • 김광희;김광일;권영규;이용현
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2003년도 제5회 영호남 학술대회 논문집
    • /
    • pp.93-93
    • /
    • 2003
  • Photoluminescence(PL) properties of Silicon nanocrystals (nc-Si) as a function of temperature is reported to consider the mechanism of PL. Nc-Si has been made by $Si^+$ ion-implantation into thermal $SiO_2$ and subsequent annealing. And after gold had been diffused at the same samples above, the resultant PL spectra has been compared to the PL spectra from the non-gold doped nc-Si. PL peak energy variation from nc-Si is same with the variation of energy bandgap of bulk silicon as temperature changes from 6 K to room temperature. This result may mean nc-Si is still indirect transition material like bulk silicon. Gold doped nc-Si reveals short peak wavelength of PL spectrum than gold undoped one. PL peak shift through gold doing process shows clearly the PL mechanism is not from defect or interface states. PL intensity increases from 6K to a certain temperature and then decrease to room temperature. This characteristic with temperature shows that phonon have a role for the luminescence as theory explains that electron and hole can be recombined radiatively by phonon's assist in nc-Si, which is almost impossible in bulk silicon. Therefore luminescence is observed in nc-Si constructed less than a few of unit cell and the peak energy of luminescence can be higher than the bulk bandgap energy by the bandgap widening effect occurs in nanostructure.

  • PDF