• 제목/요약/키워드: PJP

검색결과 15건 처리시간 0.023초

Value of Bronchoalveolar Lavage Fluid Cytology in the Diagnosis of Pneumocystis jirovecii Pneumonia: A Review of 30 Cases

  • Sung, Ji-Youn;Han, Joung-Ho;Oh, Young-Lyun;Suh, Gee-Young;Jeon, Kyeong-Man;Kim, Tae-Eun
    • Tuberculosis and Respiratory Diseases
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    • 제71권5호
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    • pp.322-327
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    • 2011
  • Background: Pneumocystis jirovecii is a fungus that has become an important cause of opportunistic infections. We present a summary of the clinical status and findings from bronchoalveolar lavage (BAL) of patients with Pneumocystis jirovecii pneumonia (PJP). Methods: We selected 30 cases of PJP that were proven through a surgical specimen evaluation. BAL fluid cytology was reviewed, and agreement with the initial diagnosis was evaluated. Results: All 30 cases of PJP occurred in immunocompromised patients. Only 15 of the 30 cases were initially diagnosed as PJP. We found PJP in 13 of the 15 cases that were negative at the initial diagnosis. The most characteristic finding of PJP was frothy exudates, and BAL fluid tended to show rare neutrophils. Two of seven patients with PJP and diffuse alveolar damage (DAD) revealed no frothy exudates in BAL fluid. Conclusion: BAL fluid cytology was reconfirmed as a sensitive and rapid method to diagnose PJP. We must be aware of the possibility of PJP to maintain high diagnostic sensitivity. We cannot exclude PJP in cases of PJP with DAD, even if frothy exudates are not observed in the BAL fluid.

Proposal of a Selective Prophylaxis Strategy Based on Risk Factors to Prevent Early and Late Pneumocystis jirovecii Pneumonia after Renal Transplantation

  • Lee, Ho;Han, Ahram;Choi, Chanjoong;Ahn, Sanghyun;Min, Sang-il;Min, Seung-Kee;Lee, Hajeong;Kim, Yon Su;Yang, Jaeseok;Ha, Jongwon
    • 대한이식학회지
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    • 제32권4호
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    • pp.92-103
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    • 2018
  • Background: Currently, trimethoprim-sulfamethoxazole is used for Pneumocystis jirovecii pneumonia (PJP) prophylaxis, but it is associated with frequent adverse effects. This study evaluated the efficacy and safety of the current protocol and proposes an individualized risk-based prophylaxis protocol. Methods: The PJP incidence and risk factors during the first 6 months (early PJP) and afterwards (late PJP) was assessed in renal transplant recipients with (prophylaxis group) and without (no-prophylaxis group) 6-month PJP prophylaxis. Results: In 578 patients, there were 39 cases of PJP during a median follow-up of 51 months. Renal adverse events were encountered frequently during trimethoprim-sulfamethoxazole prophylaxis, leading to premature discontinuation. Patients without the prophylaxis had a significantly higher incidence of early PJP (n=27, 6.6%) compared to patients with the prophylaxis (n=0). The incidence of late PJP was 2.2%, without between-group differences. The factors associated with early PJP were preoperative desensitization and acute rejection within 1 month, whereas late PJP was associated with age, deceased donor transplant, and acute rejection requiring antithymocyte globulin treatment. Conclusions: Based on the simulation results of several risk-based scenarios, the authors recommend universal prophylaxis up to 6 months post-transplant and extended selective prophylaxis in patients aged ${\geq}57$ years and those with a transplant from deceased donors.

공공봉사동기가 직무만족 및 인지된 직무성과에 미치는 영향: 구성원-조직 적합성의 매개효과를 중심으로 (The Effect of Public Service Motivation on Job Satisfaction and Perceived Job Performance: Focusing on the Mediation Effect of Person-Organization Fit)

  • 이강문;노태우
    • 디지털융복합연구
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    • 제15권9호
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    • pp.155-165
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    • 2017
  • 본 연구는 공공기관에서 공공봉사동기(PSM)이 구성원의 직무만족(JS)과 인지된 직무성과(PJP)에 미치는 직접적인 영향을 확인함과 동시에 간접적으로 종속변수에 영향을 미치는데 기여하는 매개변수의 존재와 효과를 파악하고자 하였다. 특히 매개변수로 활용된 구성원과 조직의 적합성 개념(POF)은 인사제도의 적합성으로 정의함으로써 PSM와 개인 및 조직 효과성 사이에서 인사제도 적합성의 영향력을 파악하였다. 이에 창원시 보건소 구성원을 대상으로 진행된 설문자료를 토대로 정량적 분석을 실시하고 다음과 같은 결과를 확인할 수 있었다. 첫째, 통합된 공무 조직에서의 PSM은 JS와 PJP에 긍정적인 영향을 미치는 것으로 나타났다. 둘째, PSM은 조직구성원의 JS와 PJP를 높여주지만, POF의 역할도 유의미함을 확인하였다. 이를 통해 PSM은 구성원과 조직 간 제도적 적합성을 통해 직무만족과 업무성과의 향상을 기대할 수 있다는 결론을 도출 할 수 있다.

Experimental evaluation of pumpjet propulsor for an axisymmetric body in wind tunnel

  • Suryanarayana, Ch.;Satyanarayana, B.;Ramji, K.;Saiju, A.
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제2권1호
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    • pp.24-33
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    • 2010
  • Design of a Pump Jet Propulsor (PJP) was undertaken for an underwater body with axisymmetric configuration using axial/low compressor design techniques supported by Computational Fluid Dynamics (CFD) analysis for performance prediction. Experimental evaluation of the PJP was earned out through experiments in a Wind Tunnel Facility (WTF) using momentum defect principle for propulsive performance prior to proceeding with extensive experimental evaluation in towing tank and cavitation tunnel. Experiments were particularly conducted with respect to Self Propulsion Point (SPP), residual torque and thrust characteristics over a range of vehicle advance ratio in order to ascertain whether sufficient thrust is developed at the design condition with least possible imbalance torque left out due to residual swirl in the slip stream. Pumpjet and body models were developed for the propulsion tests using Aluminum alloy forged material. Tests were conducted from 0 m/s to 30 m/s at four rotational speeds of the PJP. SPP was determined confirming the thrust development capability of PJP. Estimation of residual torque was carried out at SPP corresponding to speeds of 15, 20 and 25 m/s to examine the effectiveness of the stator. Estimation of thrust and residual torque was also carried out at wind speeds 0 and 6 m/s for PJP RPMs corresponding to self propulsion tests to study the propulsion characteristics during the launch of the vehicle m water where advance ratios are close to Zero. These results are essential to assess the thrust performance at very low advance ratios to accelerate the body and to control the body during initial stages. This technique has turned out to be very useful and economical method for quick assessment of overall performance of the propulsor and generation of exhaustive fluid dynamic data to validate CFD techniques employed.

Growth Performance, Carcass and Meat Characteristics of Black Goat Kids Fed Sesame Hulls and Prosopis juliflora Pods

  • Abdullah, Abdullah Y.;Obeidat, Belal S.;Muwalla, Marwan M.;Matarneh, Sulaiman K.;Ishmais, Majdi A. Abu
    • Asian-Australasian Journal of Animal Sciences
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    • 제24권9호
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    • pp.1217-1226
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    • 2011
  • Finding alternative feeds, such as sesame hulls and Prosopis juliflora species can attenuate difficulties of feed shortage and reduce the cost of animal feed in arid and semi-arid countries. Thirty-two Black male kids with similar initial weights (BW = $16.7{\pm}0.80\;kg$) and $120{\pm}5\;d$ of age, were used to evaluate the effect of replacing barley grains and soybean meal with Prosopis juliflora pods (PJP) and sesame hulls (SH) on growth performance, digestibility and carcass and meat characteristics. Kids were equally divided into four dietary treatment groups for an 84-d fattening period. Treatment diets had similar crude protein (CP) and metabolizable energy (ME). The treatment groups were: (T1) no PJP nor SH, (T2) 10% PJP and 20% SH, (T3) 15% PJP and 15% SH, and (T4) 20% PJP and 10% SH. A tendency was detected (p<0.08) for dry matter (DM), crude protein (CP), organic matter (OM) and neutral detergent fiber (NDF) intakes that were greater for T2 than T3 and T4 while T1 was not different from all other treatment groups. Ether extract (EE) intake was the greatest (p<0.05) for T2 and the lowest for T1. Acid detergent fiber (ADF) intake was greater (p<0.05) for T2 than T1 while T3 and T4 were intermediate. Final live weight, average daily gain (ADG) and feed conversion ratio (FCR) were comparable among different treatment groups. Digestibility of DM, OM, CP, NDF and ADF were similar among all treatment groups, however, EE digestibility was the lowest (p<0.05) for T1 when compared to other treatments. In addition, nitrogen intake, nitrogen in urine and retained and retention percentages were similar among all treatment groups. However, N loss in feces was higher (p<0.05) for T2 than T3 and T4 while T1 was intermediate. No differences were observed among treatment groups with respect to fasting live weight, hot and cold carcass weights, dressing-out percentages, mesenteric fat, visceral organs, carcass cuts percentages and carcass linear dimensions. No differences were also observed for dissected loin, leg, rack and shoulder tissues except in the total bone % for loin cuts and in the meat to bone ratio for rack cuts. T3 has the greatest total bone % and the lowest meat to bone ratio when compared to all other treatment groups. No differences were observed between treatment groups in all quality characteristics of the longissimus muscle. The present study demonstrates the potential of using PJP and SH for growing kids without adverse effects on growth performance, carcass characteristics and meat quality.

부분용입용접 내진기둥 이음부의 강도평가 (Experimental Evaluation of Seismic Column Splice with Partial Joint Penetration Welds)

  • 이철호;김재훈;김정재;오상훈
    • 한국강구조학회 논문집
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    • 제20권6호
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    • pp.817-827
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    • 2008
  • 본 연구에서는 기존 SM490강재와 국내에서 최근 개발된 내진용강재(SHN490, SN490)로 이루어진 특수모멘트골조의 기둥이음부를 부분용입용접으로 설계하여 내진성능평가를 위한 실물대 실험을 실시하였다. 부분용입용접에 의한 기둥이음부는 용접비용 및 공기의 절감에서 매력적 인 방안이다. 그러나 과거에 외국에서 수행된 몇몇 실험결과에 의하면 부분용입용접에 의한 후판기둥의 이음부는 인장응력에 대해 취성파단하는 거동을 보였다. 이런 이유로 인해 최근의 내진설계기준에서는 특수모멘트골조의 부분용입용접 기둥이음부의 강도는 예상 기둥소성모멘트 이상의 강도를 요구한다. 이를 반영하여 시험체의 부분용입용접 이음부의 설계강도는 AISC-LRFD의 기준식을 적용하여 기둥의 예상 소성모멘트 이상이 되도록 설계 및 제작하고 3등분점 하중으로 단조가력하였다. 압연형강 시험체 2개 및 조립형강 시험체 2개(총 4개 시험체)의 이음부 모두에서 기둥의 실제 소성모멘트 이상의 강도를 발휘하였다. 즉 AISC-LRFD의 부분용입용접 설계강도식의 신뢰성을 확인할 수 있었다. 다만 SM490 압연형강 시험체는 기둥의 소성모멘트를 발휘한 후 이음부에서 급격한 취성파단이 발생하였다. 이는 용접결함과 플랜지의 강도미달에 따른 복합적 원인에 의한 것으로 추정된다. 특히 SM490 강재의 경우는 항복강도와 인장강도가 규정치에 미달하는 등 성능편차가 큰 것으로 나타났다. 제한적 실험결과이긴 하지만 소재물성 및 이음부 거동의 측면 모두에서 내진용 신강재가 기존강재에 비해 전체적으로 우수함을 보여준 결과라 할 수 있다.

다발성 골수종 환자에서 발생한 육아종성 폐포자충 폐렴의 컴퓨터단층촬영 소견 (CT Findings of Granulomatous Pneumocystis jiroveci Pneumonia in a Patient with Multiple Myeloma)

  • 신소라;김태성;한정호
    • 대한영상의학회지
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    • 제83권1호
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    • pp.218-223
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    • 2022
  • 폐포자충 폐렴의 전형적인 전산화단층촬영 소견은 양측 폐에 미만성 혹은 다발성의 간유리 음영으로 잘 알려져 있지만, 드물게 다발성 폐 결절 형태로 나타날 수도 있다. 본 저자들은 다발성 골수종 치료로 인해 면역력이 저하된 환자의 양측 폐에 생긴 광범위한 간유리음영 및 이와 동반된 다발성 괴사성 늑막하 결절들이 경피적 폐생검을 통해 육아종성 폐포자충 폐렴으로 확진된 증례를 보고한다.

Political - Legal Reflections on the Two Epochal "Antique" Documents on" Peaceful Use" in the History of Japanese Space Policy

  • Tomitaro, Yoneda
    • 한국항공우주법학회:학술대회논문집
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    • 한국항공우주법학회 2008년도 제40회 국제학술발표대회
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    • pp.219-231
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    • 2008
  • " Analyzing on an object in the sphere of domestic law with the method of international law" has been already on the horizon in international law. For the lawyers of international law and space law, it is quite natural that they utilize the method of international law, whatever objects they may choice. The reason is that the characteristic of international law do not depend upon object in itself, but depend upon method in itself. The object of this paper is the idea of Peaceful Use(IPU or PU) in Japanese Space Policy. The method to be applied to this analysis is the international law's interpretation theory on legal principles, i.e., the method of international law. One of the aims of this paper is to explain critically the need of review on IPU in Japanese Space Policy; in particular with respect to the positive reconstruction of IPU through historical analyzing on the transfiguration and the mere shell of the Post-War Japanese Pacifism(PJP) as the starting point of IPU The historical process of the transfiguration and the mere shell is as followed .i.e.," from the ultranationalism in the pre-war Japan to PJP in the post-war Japan, from PJP to IPU, and from IPU to IPU's regression. In particular with respect to the interpretation theory, the meaning of the teleological, aims and objects school's approach on the interpretation of legal principles(P) has been emphasized. The reason is that the promising development of IPU will be realized by cooperating with the interpretation theory on P in international law. At the end of the beginning, I'd like to quote K. Marx's thesis in order to make the positions and missions the lawyers of international law and space clear. It is as follows, i.e.," THE PHILOSOPHERS HAVE ONLY INTERPRETED THE WORLD IN VARIOUS WAYS - THE POINT, HOWEVER IS TO CHANGE IT.

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Political - Legal Reflections on the Two Epochal "Antique" Documents on "Peaceful Use" in the History of Japanese Space Policy

  • Tomitaro, Yoneda
    • 항공우주정책ㆍ법학회지
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    • 제23권1호
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    • pp.169-188
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    • 2008
  • Analyzing on an object in the sphere of domestic law with the method of international law has been already on the horizon in international law. For the lawyers of international law and space law, it is quite natural that they utilize the method of international law, whatever objects they may choice. The reason is that the characteristic of international law do not depend upon object in itself, but depend upon method in itself. The object of this paper is the idea of Peaceful Use(IPU or PU) in Japanese Space Policy. The method to be applied to this analysis is the international law's interpretation theory on legal principles, i.e., the method of international law. One of the aims of this paper is to explain critically the need of review on IPU in Japanese Space Policy; in particular with respect to the positive reconstruction of IPU through historical analyzing on the transfiguration and the mere shell of the Post-War Japanese Pacifism(PJP) as the starting point of IPU. The historical process of the transfiguration and the mere shell is as followed, i.e., "from the ultra-nationalism in the pre-war Japan to PJP in the post-war Japan, from PJP to IPU, and from IPU to IPU's regression. In particular with respect to the interpretation theory, the meaning of the teleological, aims and objects school's approach on the interpretation of legal principles(P) has been emphasized. The reason is that the promising development of IPU will be realized by cooperating with the interpretation theory on P in international law. At the end of the beginning, I'd like to quote K. Marx's thesis in order to make the positions and missions the lawyers of international law and space clear. It is as follows, i.e., "THE PHILOSOPHERS HAVE ONLY INTERPRETED THE WORLD IN VARIOUS WAYS - THE POINT, HOWEVER IS TO CHANGE IT.

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Cavitation studies on axi-symmetric underwater body with pumpjet propulsor in cavitation tunnel

  • Suryanarayana, Ch.;Satyanarayana, B.;Ramji, K.;Rao, M. Nageswara
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제2권4호
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    • pp.185-194
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    • 2010
  • A pumpjet propulsor (PJP) was designed for an underwater body (UWB) with axi-symmetric configuration. Its performance was predicted through CFD study and models were manufactured. The propulsor design was evaluated for its propulsion characteristics through model tests conducted in a Wind Tunnel (WT). In the concluding part of the study, evaluation of the cavitation performance of the pumpjet was undertaken in a cavitation tunnel (CT). In order to assess the cavitation free operation speeds and depths of the body, cavitation tests of the PJP were carried out in behind condition to determine the inception cavitation numbers for rotor, stator and cowl. The model test results obtained were corrected for full scale Reynolds number and subsequently analyzed for cavitation inception speeds at different operating depths. From model tests it was also found that the cavitation inception of the rotor takes place on the tip face side at higher advance ratios and cavitation shifts towards the suction side as the RPS increases whereas the stator and cowl are free from cavitation.