• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.3
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• pp.207-214
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• 2008

Objective : This study report the effect of traditional medical treatment on postherpetic neuralgia(PHN) 2 cases. Methods : We observed 2 PHN cases diagnosed Ganwoolqiche and prescribed herbal medication (Soyosan-Gagambang & Punsimgieum-Gamibang) for each case. Results : Both cases showed efficient clinical results, especially for the pains. Conclution : In this study, operated traditional medical treatment on PHN cases and could find good progress after treatment.

• Journal of Microbiology
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• v.37 no.4
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• pp.224-228
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• 1999

Benzaldehyde dehydrogenase (BZDH), an enzyme involved in the degradation of toluene and xylenes, is encoded by the phnN gene of Pseudomonas sp. strain DJ77. We determined the nucleotide sequence of a DNA fragment of 1,803 base pairs which included the phnN gene. The fragment contained an open reading frame of 1,506 base pairs to accommodate th 55 kDa sized enzyme encoding BZDH. The enzyme efficiently oxidized benzaldehyde, salicylaldehyde, m-tolualdehyde and ps-tolualdehyde.

• Journal of Acupuncture Research
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• v.38 no.4
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• pp.245-256
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• 2021

The purpose of this study was to analyze the Korean medicine treatment methods for Postherpetic Neuralgia (PHN) in Korea. There were 5 online databases searched (OASIS, NDSL, RISS, KISS and KMBASE) for studies which were related to PHN. A total of 12 studies were selected. Various treatments such as acupuncture, herbal medicine, and moxibustion were reported treatments for PHN, some of which included Western medicine and Korean medicine treatment. Korean herbal medicine was the most frequently used treatment method, followed by manual acupuncture. Sipjeondaebotanggami was the most frequently used prescription. Poria Sclerotium was the most frequently used principal herb, followed by Angelicae Gigantis Radix, Zingiberis Rhizoma, and Ginseng Radix. GB44, LI4, LR3 were the common acupoints used for the treatment of PHN. CV12 was the most frequently used moxibustion point, and gabapentin was the most frequently used concomitant Western drug. Additional research on Korean medicine treatment of PHN is expected in the future.

• The Korean Journal of Pain
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• v.30 no.1
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• pp.3-17
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• 2017

Background: Postherpetic neuralgia (PHN) is a common and painful complication of acute herpes zoster. In some cases, it is refractory to medical treatment. Preventing its occurrence is an important issue. We hypothesized that applying nerve blocks during the acute phase of herpes zoster could reduce PHN incidence by attenuating central sensitization and minimizing nerve damage and the anti-inflammatory effects of local anesthetics and steroids. Methods: This systematic review and meta-analysis evaluates the efficacy of using nerve blocks to prevent PHN. We searched the MEDLINE, EMBASE, Cochrane Library, ClinicalTrials.gov and KoreaMed databases without language restrictions on April, 30 2014. We included all randomized controlled trials performed within 3 weeks after the onset of herpes zoster in order to compare nerve blocks vs active placebo and standard therapy. Results: Nine trials were included in this systematic review and meta-analysis. Nerve blocks reduced the duration of herpes zoster-related pain and PHN incidence of at 3, 6, and 12 months after final intervention. Stellate ganglion block and single epidural injection did not achieve positive outcomes, but administering paravertebral blockage and continuous/repeated epidural blocks reduced PHN incidence at 3 months. None of the included trials reported clinically meaningful serious adverse events. Conclusions: Applying nerve blocks during the acute phase of the herpes zoster shortens the duration of zoster-related pain, and somatic blocks (including paravertebral and repeated/continuous epidural blocks) are recommended to prevent PHN. In future studies, consensus-based PHN definitions, clinical cutoff points that define successful treatment outcomes and standardized outcome-assessment tools will be needed.

• The Korean Journal of Pain
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• v.26 no.3
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• pp.242-248
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• 2013

Varicella (chickenpox) is a highly contagious airborne disease caused by primary infection with the varicella zoster virus (VZV). Following the resolution of chickenpox, the virus can remain dormant in the dorsal sensory and cranial ganglion for decades. Shingles (herpes zoster [HZ]) is a neurocutaneous disease caused by reactivation of latent VZV and may progress to postherpetic neuralgia (PHN), which is characterized by dermatomal pain persisting for more than 120 days after the onset of HZ rash, or "well-established PHN", which persist for more than 180 days. Vaccination with an attenuated form of VZV activates specific T-cell production, thereby avoiding viral reactivation and development of HZ. It has been demonstrated to reduce the occurrence by approximately 50-70%, the duration of pain of HZ, and the frequency of subsequent PHN in individuals aged ${\geq}50$ years in clinical studies. However, it has not proved efficacious in preventing repeat episodes of HZ and reducing the severity of PHN, nor has its long-term efficacy been demonstrated. The most frequent adverse reactions reported for HZ vaccination were injection site pain and/or swelling and headache. In addition, it should not be administrated to children, pregnant women, and immunocompromised persons or those allergic to neomycin or any component of the vaccine.

• The Korean Journal of Pain
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• v.24 no.3
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• pp.154-157
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• 2011

Background: Postherpetic neuralgia (PHN) is usually managed pharmacologically. It is not uncommon for patients with chronic kidney disease (CKD) to suffer from PHN. It is difficult to prescribe a sufficient dose of anticonvulsants for intractable pain because of the decreased glomerular filtration rate. If the neural blockade and pulsed radiofrequency ablation provide only short-term amelioration of pain, spinal cord stimulation (SCS) with a low level of evidence may be used only as a last resort. This study was done to evaluate the efficacy of spinal cord stimulation in the treatment of PHN in patients with CKD. Methods: PHN patients with CKD who needed hemo-dialysis who received insufficient relief of pain over a VAS of 8 regardless of the neuropathic medications were eligible for SCS trial. The follow-up period was at least 2 years after permanent implantation. Results: Eleven patients received percutaneous SCS test trial from Jan 2003 to Dec 2007. Four patients had successfully received a permanent SCS implant with their pain being tolerable at a VAS score of less than 3 along with small doses of neuropathic medications. Conclusions: SCS was helpful in managing tolerable pain levels in some PHN patients with CKD along with tolerable neuropathic medications for over 2 years.

• Research in Community and Public Health Nursing
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• v.1 no.1
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• pp.88-102
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• 1989

This survey was conducted in order to find out the degree of health service activities of Public Health Nurses & variables relevant to their activities. The subjects of this survey were 232 PHN in Health Centers, Inchon & Kyung Gi area. Data were collected by mean of questionairs from 30th, September to 30th, October, 1986. For the analysis, ANOVA was used. The results were as follows; 1. General characteristics of PHN: o An approximately four fifth of the subjects (82.3%) was between 20-39 years. o The average career length of the subjects as PHN was 4 years. o Their educational level was almost Nursing School (22.4%) Junior College of Nursing (53.4%). o The marital status of the subjects was already married (75.4%). 3. The degree of health service activities of PHN; o The total mean of health service activities was 2.147 (S.D: 1.477, range 11-5). o Among the 11 Health Service Categories; Health service planning (2.828) is the highest mean scored category. The lowest mean scored category was the other health services. o Among the specific activity items about the 11 health service categories, the highest scored activities were 'personal counselling & education' in well-baby care (2.504), family planning (2.530), Tb control (2.134), disease control (2.371), 'health history taking & health examination', in prenatal care, 'clinic care', in administrative service, 'record & report', in the other categories. o Almost categories (10), 'Home visiting' was the lowest scored activity. 3. The relevance for the health service activities by several variables were as follows; o The relevance for the health service activities by general characteristics of PHN was not shown significance at age, educational level, marital status, relegion status. o And at work place, & work department was shown high significance.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.669-676
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• 2004

Post-herpetic neuralgia(PHN) is a chronic pain syndrome associated with the reactivation of a primary infection with varicella zoster virus(chinken pox), which leads to a chronic infection of dorsal root ganglia. The most common risk factor for shingles and its potential sequela, PHN, is advanced age. For a significant number of patients, the pain following healing of shingles can persist for months to years. If this pain, classified as PHN, persists longer than one month. PHN often leads to depression, disrupted sleep, decreased productivity, and utilization of health care. We treated a 60 year-old female patient who suffered pain and headache after Stellate Ganglion Blocks(SGB). In identifying points for differentiation of syndrom(辨證), this subject was diagnosed as Yangmyeong Merdian wind-heat syndrom(陽明經風熱證) and was administered Seungmagalgeuntanggamibang(revised Shengmagalgen-tang, 升麻葛根湯加味方). To ease pain, Western medication was administered as well. After fourteen days of treatment, pain and other symptoms improved.

• ETRI Journal
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• v.36 no.4
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• pp.537-544
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• 2014

In this paper, we present a new inter-carrier interference (ICI) self-cancellation scheme - namely, ISC scheme - for orthogonal frequency-division multiplexing systems to reduce the ICI generated from phase noise (PHN) and residual frequency offset (RFO). The proposed scheme comprises a new ICI cancellation mapping (ICM) scheme at the transmitter and an appropriate method of combining the received signals at the receiver. In the proposed scheme, the transmitted signal is transformed into a real signal through the new ICM using the real property of the transmitted signal; the fast-varying PHN and RFO are estimated and compensated. Therefore, the ICI caused by fast-varying PHN and RFO is significantly suppressed. We also derive the carrier-to-interference power ratio (CIR) of the proposed scheme by using the symmetric conjugate property of the ICI weighting function and then compare it with those of conventional schemes. Through simulation results, we show that the proposed ISC scheme has a higher CIR and better bit error rate performance than the conventional schemes.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.3
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• pp.160-167
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• 2012

Objective : This study reports the effect of oriental medicine with depletion and cupping therapy on post-herpetic neuralgia(PHN) 1 case. Methods : We experienced one case of PHN treated by oriental medical treatment with depletion and cupping therapy. To evaluate the effectiveness of this treatment, we used the Visual Analogue Scale(VAS). Result : After the treatment the grade of VAS was decreased and clinical symptoms were improved. Conclusion : Oriental medicine with depletion and cupping therapy can be available for relieving symptoms related with PHN.