• Asian-Australasian Journal of Animal Sciences
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• 제5권1호
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• pp.29-32
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• 1992

The effects of prostaglandins (PG) and indomethacin, a PG synthesis inhibitor, on ovulation in the perfused fowl ovary were studied. Laying hens were killed by cutting the jugular vein 18-19 h before expected ovulation of the second follicle of a clutch sequence. The cannulated ovary was dissected free and connected with a recycling perfusion apparatus. Agents to be studied for their effects on ovulation were added to the perfusion fluid. $PGF_{2{\alpha}}$ at 0.1 and 1 mg/l induced ovulation, with a success rate of 25% and 30%, respectively. The same doses of $PGE_2$ were effective at 60% and 63%, respectively. Indomethacin partially blocked gonadotrophin-induced ovulation. It is suggested that PGs may play a supportive role in the process of follicular rupture in the domestic fowl.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.132-132
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• 2001

Proinflamamtory mediators such as prostaglandins (PGs), cyclooxygenase-2 (COX-2), and inducible nitric oxide synthase (iNOS) are known to be key mediators in pathogenesis of inflammatory diseases. Capsaicin, the major ingredient of hot pepper, is considered to elicit anti-inflammatory property. In this study, the effect of capsaicin on the prostaglandin E$_2$(PGE$_2$) production was investigated in murine peritoneal macrophages.(omitted)

• 미생물학회지
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• 제26권3호
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• pp.149-154
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• 1988

Japanese Encephalitis Virus(JEV) can be detected conveniently by the use of biotinylated cDNA probe. To prepare biotinylated probe aminoallyl dUTP was first synthesized chemically to reverse transcribe the virial RNA. The allylamine-labeled cDNA was then converted to the biotin-cDNA by the reaction with an activated biotin ester, NHS-ACA-biotin. The JEV genomic RNA was hybridized to the biotinylated cDNA probe on nitrocellulose filter and visualized colorimetrically by streptavidin complexes with alkaline phosphatase polymer. Sensitivity of the detection system was determined by estimating the amount of the JEV genomic RNA through comparison with signals generated from the biotinylated and $^{32/P}$ -labeled probes. It was found that the biotin probe was as sensitive as $^{32/P}$ -cDNA probe which can detect 50pgs of the target RNA.

• 약학회지
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• 제43권1호
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• pp.117-123
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• 1999

Because of the potent effects of lipid mediators such as prostaglandins (PGs), leukotriens (LTs) and platelet activating factor (PAF) on a variety of cells and tissues, they are considered as major contributors to the process leading to inflammation and allergy. To pursue the mechanism of anti-inflammatory activity of Lonicera japonica, we tested inhibitory effects of 7 flavonoids from Lonicera japonica on arachidonic acid cascade related enzymes, such as inflammatory phospholipase $A_2$, cyclooxygenase-1 and 2, 5-lipoxygenase, in bone marrow derived mast cell (BMMC), and lyso PAF-acetyltransferase in rat spleen microsomes. Anti-inflammatory activities of lonicera japonica are thought to be attributed at least in part to the inhibition of arachidonic acid cascade releated enzymes by flavonoids such as apigenin, luteolin quercetin.

• 약학회지
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• 제47권2호
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• pp.69-77
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• 2003

Arachidonic acid (AA), which is stored in membrane glycerophospholipids, is liberated by phospholipase $A_2$ (PLA$_2$) enzymes and is sequentially converted to cyclooxygenases (COXs) and lipoxygenases (LOXs) then to various bioactive PGs, and LTs. In order to find the specific inhibitors of AA metabolism especially PLA$_2$, COX-2, 5-LO and lyso PAF acetyltransferase, 120 Korean residential plants extracts were evaluated for their inhibitory activity on PGD$_2$, LTC$_4$ production from cytokine-induced mouse bone marrow-derived mast cells (BMMC) and arachidonic acid released from phospholipid and PAF production from lyso PAF. From this screening procedure, methanol extract of ten indigenous plant such as Salix gracilistyla, Sedum kamtschaticum, Cirsium chanroenicum, Hypericum ascyron, Astilbe chinensis, Agrimonia pilosa, Aristolochia manshuriensis, Vodia daniellii, Pyrola japonica, Styrax obassia were found to inhibit production of inflammatory mediators in vitro assay system.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 추계학술대회
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• pp.176-177
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• 2011

현재, 해양 선박의 경우 주간에는 육안을 통하여 쉽게 항구를 찾아 쉽게 선박을 정박시키거나 출항을 할 수 있지만, 사람의 시야를 확보할 수 없는 야간의 경우에는 선박의 전자 장비에 의존하거나 해상위에 떠 있는 해상 유도 표시등을 이용하여 선박을 정박시키거나 출항을 하고 있다. 또한, 현재의 많은 해상 유도 표시등은 GPS를 사용하여 제품을 설계하고 있지만, 시간에 따른 점멸 제어에 대한 오차가 누적되어 일정시간의 경과 후에는 유도등의 동기화에 많은 문제가 발생하고 있는 실정이다. 본 논문에서는 야간에 선박의 안전한 출항과 정박의 안내를 위하여 해상 유도 표시등의 동시 점멸에 관한 논문으로 PGS 시간 정보 데이터를 이용하여 일정시간이 흘러간 뒤에도 유도등의 점멸 제어 누적 오차를 제거할 수 있는 알고리즘을 개발하여 기존의 제품을 보완할 수 있는 알고리즘을 제안하고 그 성능을 실험을 통하여 제시하고자 한다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2004년도 추계학술발표논문집(상)
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• pp.623-626
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• 2004

EVM(Embedded Virtual Machine)은 임베디드 시스템을 위한 가상기계로서 플랫폼에 독립적이며, 모바일 디바이스와 디지털 TV등에 탑재할 수 있는 핵심 기술로 다운로드 솔루션에서는 꼭 필요한 기술이다. SIL(Standard Intermediate Language)은 임베디드 시스템을 위한 가상기계의 표준 중간 언어로 객체지향 프로그래밍 언어와 순차 적인 프로그래밍언어를 모두 수용할 수 있다. SIL로 기술된 프로그램이 EVM 에서 실행되기 위해서는 EFF(Executable File Format)형태로 변환되어야 한다. 임베디드 시스템을 위한 실행 파일 포맷인 EFF 는 구조가 간결하며 확장이 용이한 특징을 지닌다. 또한 메타데이터와 표준 중간 언어가 서로 독립적으로 구성되어 분석이 쉽고 타입 체크가 편리한 구조이다. 본 논문에서는 가상기계를 위한 표준 중간 언어인 SIL 을 EVM 에서 실행 가능한 형태로 변환시켜주는 실행 파일 포맷 생성기(EFF Generator)를 설계하고 구현한다. 먼저, SIL 구조를 위한 SIL 문법을 설계하고 파서 생성기(PGS)를 사용하여 SIL 프로그램을 위한 어휘분석기와 구문분석기를 구현한다. 그리고 AST를 생성한 후. 포맷 생성기를 통하여 AST를 운행하며 EFF를 생성한다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.102.1-102.1
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• 2003

Phospholipase A$_2$(PLA$_2$) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid(AA), a precursor of eicosanoids including prostaglandins(PGs) and leukotrienes (LTs). The same reaction also produces lyso-phospholipids. So far, at least 19 enzymes that possess PLA2 activity have been identified, consists of low-molecular-weight, Ca$\^$2+/-requiring, secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, host defense, and atherosclerosis. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.260.1-260.1
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• 2002

Green tea contains several antioxidants including polyphenols of the catechin. which have been shown to act in vitro and in vivo as anti-inflammatory. anti-viral and anti-tumor drugs. Prostaglandins (PGs) are a family of intercellular and intracellular messengers derived from arachidonic acid(AA) by phospholipase(PL) and cyclooxygenase(COX). These mediators exert a wide range of effects on processes such as smooth muscle tone. vascular permeability, cellular proliferation. and inflammatory/immune function. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.258.1-258.1
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• 2002

Piperine (piperinoyl-piperidine) is a nitrogenous pungent substance contained in black pepper. the well know spice obtained from Piper nigrum L. (Piperaceae). Pharmacological studies have shown that piperine reduces inflammation and pain. possesses anticonvulsant and antiulcer activity. protects the liver and has deleterious effects on testis function. Prostaglandins(PGs) are a family of intercellular and intracellular messengers derived from arachidonic acid(AA) by phospholipase(PL) and cyclooxygenase(COX). (omitted)