• 제목/요약/키워드: PDR

검색결과 228건 처리시간 0.027초

Molecular Diagnosis of Taenia saginata Tapeworms from Two Residents of Northern Cambodia

  • Chang, Taehee;Jung, Bong-Kwang;Sohn, Woon-Mok;Hong, Sooji;Shin, Hyejoo;Ryoo, Seungwan;Lee, Jeonggyu;Lee, Keon Hoon;Khieu, Virak;Huy, Rekol;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • 제58권2호
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    • pp.201-204
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    • 2020
  • Taenia saginata infection has seldom been reported in Cambodia. In this study, we performed a survey of intestinal parasites in 1,156 residents of Preah Vihear and Stung Treng Provinces in 2018. The results revealed that 26 (2.4%) cases were positive for Taenia spp. eggs. In order to obtain the strobilae of the tapeworms, 2 patients in Preah Vihear were treated with praziquantel and purged with magnesium salts. The proglottids expelled after the medication were morphologically and molecularly analyzed to determine the species. The main uterine lateral braches in gravid proglottids were > 15 in number suggesting that they are either T. saginata or Taenia asiatica. The sequences of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene and 2 nuclear loci, elongation factor-1 alpha (ef1) and ezrin-radixin-moesin-like protein (elp), were identical to the sequences of T. saginata available in GenBank but distant from Taenia solium, T. asiatica, and T. saginata-T. asiatica hybrid. This is the first report of the presence of T. saginata in the northern part of Cambodia bordering Lao PDR based on a molecular confirmation.

An Energy- Efficient Optimal multi-dimensional location, Key and Trust Management Based Secure Routing Protocol for Wireless Sensor Network

  • Mercy, S.Sudha;Mathana, J.M.;Jasmine, J.S.Leena
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제15권10호
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    • pp.3834-3857
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    • 2021
  • The design of cluster-based routing protocols is necessary for Wireless Sensor Networks (WSN). But, due to the lack of features, the traditional methods face issues, especially on unbalanced energy consumption of routing protocol. This work focuses on enhancing the security and energy efficiency of the system by proposing Energy Efficient Based Secure Routing Protocol (EESRP) which integrates trust management, optimization algorithm and key management. Initially, the locations of the deployed nodes are calculated along with their trust values. Here, packet transfer is maintained securely by compiling a Digital Signature Algorithm (DSA) and Elliptic Curve Cryptography (ECC) approach. Finally, trust, key, location and energy parameters are incorporated in Particle Swarm Optimization (PSO) and meta-heuristic based Harmony Search (HS) method to find the secure shortest path. Our results show that the energy consumption of the proposed approach is 1.06mJ during the transmission mode, and 8.69 mJ during the receive mode which is lower than the existing approaches. The average throughput and the average PDR for the attacks are also high with 72 and 62.5 respectively. The significance of the research is its ability to improve the performance metrics of existing work by combining the advantages of different approaches. After simulating the model, the results have been validated with conventional methods with respect to the number of live nodes, energy efficiency, network lifetime, packet loss rate, scalability, and energy consumption of routing protocol.

Transcriptome Analysis Unveils Gln3 Role in Amino Acids Assimilation and Fluconazole Resistance in Candida glabrata

  • Santos, Francisco J. Perez-de los;Garcia-Ortega, Luis Fernando;Robledo-Marquez, Karina;Guzman-Moreno, Jesus;Riego-Ruiz, Lina
    • Journal of Microbiology and Biotechnology
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    • 제31권5호
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    • pp.659-666
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    • 2021
  • After Candida albicans, Candida glabrata is one of the most common fungal species associated with candidemia in nosocomial infections. Rapid acquisition of nutrients from the host is important for the survival of pathogens which possess the metabolic flexibility to assimilate different carbon and nitrogen compounds. In Saccharomyces cerevisiae, nitrogen assimilation is controlled through a mechanism known as Nitrogen Catabolite Repression (NCR). NCR is coordinated by the action of four GATA factors; two positive regulators, Gat1 and Gln3, and two negative regulators, Gzf3 and Dal80. A mechanism in C. glabrata similar to NCR in S. cerevisiae has not been broadly studied. We previously showed that in C. glabrata, Gln3, and not Gat1, has a major role in nitrogen assimilation as opposed to what has been observed in S. cerevisiae in which both factors regulate NCR-sensitive genes. Here, we expand the knowledge about the role of Gln3 from C. glabrata through the transcriptional analysis of BG14 and gln3Δ strains. Approximately, 53.5% of the detected genes were differentially expressed (DEG). From these DEG, amino acid metabolism and ABC transporters were two of the most enriched KEGG categories in our analysis (Up-DEG and Down-DEG, respectively). Furthermore, a positive role of Gln3 in AAA assimilation was described, as was its role in the transcriptional regulation of ARO8. Finally, an unexpected negative role of Gln3 in the gene regulation of ABC transporters CDR1 and CDR2 and its associated transcriptional regulator PDR1 was found. This observation was confirmed by a decreased susceptibility of the gln3Δ strain to fluconazole.

The Analysis of Hydropower Development and the Mekong Power Grid on Regional Cooperation : Focus on the Greater Mekong Subregion Program

  • Nayeon Shin;Seungho Lee
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2023년도 학술발표회
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    • pp.245-245
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    • 2023
  • This paper examines the extent to which the Mekong River Basin countries have achieved socioeconomic benefits based on regional cooperation through the Greater Mekong Subregion (GMS) Program, focusing on hydropower development and the Mekong Power Grid. This study pays attention to the time period from 2012 to 2022. The benefit sharing approach is employed to evaluate the extent to which hydropower development and the Mekong Power Grid have contributed to the regional energy trade in the GMS program. The GMS program was launched by the Asian Development Bank (ADB) in 1992, and the Chinese provinces of Yunnan and Guangxi, Myanmar, Lao PDR, Thailand, Cambodia, and Vietnam have taken an active part in the program. The goals of the GMS program are to achieve poverty alleviation, economic development, and regional cooperation in various sectors, including energy, tourism, and transportation. The GMS Economic Cooperation Program Strategic Framework 2030 (GMS-2030), in 2021, provides a new framework for prosperous and sustainable development in the river basin. In the energy sector, the GMS program has been instrumental in facilitating hydropower development and creating the Mekong Power Grid with the Regional Grid Code (RGC), contributing to economic benefits and promoting regional trade of hydroelectricity. It is argued that the GMS program has enhanced regional cooperation between the riparian countries. Despite such achievements, the GMS program has faced challenges, including the gap of economic development between the riparian countries, socioeconomic and environmental concerns regarding hydropower development between the Upper and Lower Mekong countries, and geopolitical tensions from the US-China rivalry. These challenges should adequately be addressed within the program, which can guarantee the sustainability of the program for the river basin.

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해상 통신에서 지상파 VHF 데이터 교환을 위한 간섭 인지 기반 자원 할당 기법 (Interference-aware Resource Allocation Scheme for VHF Data Exchange-terrestrial in Maritime Communication)

  • 이솔비;권정혁;나화진;김경태;문형진;김부영;심우성;김동완;김의직
    • 사물인터넷융복합논문지
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    • 제10권4호
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    • pp.109-115
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    • 2024
  • 본 논문에서는 선박이 밀집한 해안 환경에서 Automatic Identification System (AIS) 메시지 전송의 신뢰성을 보장하는 지상파 Very High Frequency (VHF) 데이터 교환 (VHF Data Exchange-Terrestrial, VDE-TER)을 위한 간섭 인지 기반 자원 할당 (Interference-aware Resource Allocation, IaRA) 기법을 제안한다. 이를 위해, IaRA는 VHF Data Exchange System (VDES) 채널 모니터링을 통해 얻은 스케줄링 정보에 기반하여 채널 선택 및 슬롯 할당을 수행한다. 시뮬레이션 결과, IaRA가 기존 VDES의 VDE-TER 자원 할당 기법과 비교하여 8.79% 높은 패킷 전달률과 9.69% 낮은 채널 간섭률을 달성하였다.

라오스 산촌마을의 생산구조전환을 위한 투자 경제성 기초 분석 (Fundamental Economic Feasibility Analysis on the Transition of Production Structure for a Forest Village in LAO PDR)

  • 이보휘;김세빈;이준우;이학준;이상진;이중구;백운기;박범진;구승모
    • 한국산림휴양학회지
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    • 제22권4호
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    • pp.11-22
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    • 2018
  • 본 연구는 라오스에 소재한 전형적인 농 산촌 마을을 선정하여, 마을 단위를 대상으로 생산구조를 전환할 경우의 소득증대에 대한 경제적 타당성을 분석하였다. 대상지는 라오스 쌍퉁구에 위치한 농부아 마을로써 산림지역이 혼재된 논농사 위주의 마을이다. 이 마을이 취할 수 있는 소득 제고 전략은 단기적으로 손쉽게 소득을 제고할 수 있는 작목으로 노니(Morinda citrifolia)가 꼽힌다. 사업 기간은 20년으로 가정하고, 1ha 면적에 $3m{\times}3m$ 간격으로 식재한 총 1,100본을 대상으로, 묘목 생존율과 노니 수매가격에 따라 시나리오 1, 2, 3을 구분하였다. 일반적으로 노니는 생장이 좋은 편이나, 본 연구에서는 생산 경험 부족, 병충해 등의 리스크를 감안하여 기본 시나리오 1을 묘목 생존율(=열매 생산량)을 기존 자료(하와이)보다 보수적으로 설정하였다. 시나리오 1은 노니 묘목의 생존율이 1년생이 50%, 2년생이 60%, 3년생부터 20년생까지 70%로 유지된다고 가정하였다. 시나리오 2는 묘목 생존율이 10%씩 감소되어 40%, 50%, 60%로 제약을 두었고, 시나리오 3은 묘목생존율이 10% 감소되고, 노니 수매가격 또한 10% 감소된 경우로 가정하였다. 이러한 조건하에 라오스 시장 할인율 10%를 기준으로, 3개 시나리오 모두 IRR이 각각 24.81%, 19.02%, 16.30%로 모두 경제성이 있음이 확인되었다. 또한 ha당 B/C도 각각 시나리오 1, 2, 3에 대해서 할인율 10%를 기준으로 모두 1.71, 1.47, 1.31로 분석되었다. 분석결과는 향후 농부아 마을은 대체 작목(노니)를 통한 저소득 영농구조를 탈피할 수 있는 좋은 계기가 될 것을 시사하며, 각종 정부 및 민간 투자사업을 계획할 때 수행하는 사전진단 절차 단계에서 유용한 의사결정 정보로써 활용이 가능하다.

Discussion of Preliminary Design Review for MIRIS, the Main Payload of STSAT-3

  • Han, Won-Yong;Jin, Ho;Park, Jang-Hyun;Nam, Uk-Won;Yuk, In-Soo;Lee, Sung-Ho;Park, Young-Sik;Park, Sung-Jun;Lee, Dae-Hee;Ree, Chang-H.;Jeong, Woong-Seob;Moon, Bong-Kon;Cha, Sang-Mok;Cho, Seoung-Hyun;Rhee, Seung-Woo;Park, Jong-Oh;Lee, Seung-Heon;Lee, Hyung-Mok;Matsumoto, Toshio
    • 한국우주과학회:학술대회논문집(한국우주과학회보)
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    • 한국우주과학회 2008년도 한국우주과학회보 제17권2호
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    • pp.27.1-27.1
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    • 2008
  • KASI (Korea Astronomy and Space Science Institute) is developing a compact wide-field survey space telescope system, MIRIS (The Multi-purpose IR Imaging System) to be launched in 2010 as the main payload of the Korea Science and Technology Satellite 3. Through recent System Design Review (SDR) and Preliminary Design Review (PDR), most of the system design concept was reviewed and confirmed. The near IR imaging system adopted short F/2 optics for wide field low resolution observation at wavelength band 0.9~2.0 um minimizing the effect of attitude control system. The mechanical system is composed of a cover, baffle, optics, and detector system using a $256\times256$ Teledyne PICNIC FPA providing a $3.67\times3.67$ degree field of view with a pixel scale of 51.6 arcsec. We designed a support system to minimize heat transfer with Muti-Layer Insulation. The electronics of the MIRIS system is composed of 7 boards including DSP, control, SCIF. Particular attention is being paid to develop mission operation scenario for space observation to minimize IR background radiation from the Earth and Sun. The scientific purpose of MIRIS is to survey the Galactic plane in the emission line of Pa$\alpha$ ($1.88{\mu}m$) and to detect the cosmic infrared background (CIB) radiation. The CIB is being suspected to be originated from the first generation stars of the Universe and we will test this hypothesis by comparing the fluctuations in I (0.9~1.2 um) and H (1.2~2.0 um) bands to search the red shifted Lyman cutoff signature.

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Serum Cathepsin B to Cystatin C Ratio as a Potential Marker for the Diagnosis of Cholangiocarcinoma

  • Monsouvanh, Ammala;Proungvitaya, Tanakorn;Limpaiboon, Temduang;Wongkham, Chaisiri;Wongkham, Sopit;Luvira, Vor;Proungvitaya, Siriporn
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권21호
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    • pp.9511-9515
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    • 2014
  • Cholangiocarcinoma (CCA) is a cancer of the bile duct epithelial cells. The highest incidence rate of CCA with a poor prognosis and poor response to chemotherapy is found in Southeast Asian countries, especially in northeastern Thailand and Lao PDR. Cathepsin B is a lysosomal cysteine protease which is regulated by cysteine proteinase inhibitors such as cystatin C. Elevation of cathepsin B levels in biological fluid has been observed in patients with inflammatory diseases and many cancers. We aimed to investigate the serum cathepsin B and cystatin C levels of CCA patients to evaluate the feasibility of using cathepsin B and cystatin C as markers for the diagnosis of CCA. Fifty-six sera from CCA patients, 17 with benign biliary diseases (BBD) and 13 from controls were collected and the cathepsin B and cystatin C levels were determined. In addition, cathepsin B expression was investigated immunohistochemically for 9 matched-pairs of cancerous and adjacent tissues of CCA patients. Serum cathepsin B, but not cystatin C, was significantly higher in CCA and BBD patient groups compared to that in the control group. Consistently, all cancerous tissues strongly expressed cathepsin B while adjacent tissues were negative in 7 out of 9 cases. In contrast, serum cystatin C levels were comparable between CCA and control groups, although serum cystatin C levels in the BBD group was higher than that in the control or CCA groups. When the serum cathepsin B to cystatin C ratio was calculated, that of the CCA group was significantly higher than that of the control group, and, although statistically not significant, the ratio of CCA group showed a trend to be higher than that of the BBD group. Thus, the cathepsin B to cystatin C ratio might be used as an alternative marker for aiding diagnosis of CCA.

라오스 느타리버섯 균사배양 배지의 적정 배합비율 (Optimal substrate mixture ratio for mycelial growth of oyster mushroom in Lao PDR)

  • 장현유;쌩소우리봉 비엥캄;비라반 파노우라트;백운호;양규남;이용하;장종근
    • 한국버섯학회지
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    • 제5권2호
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    • pp.59-64
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    • 2007
  • 라오스의 느타리버섯 수량과 품질을 향상시키기 위하여 볏짚, 왕겨, 볏짚과 왕겨의 혼합, 맥주박을 사용하여 균사 생장과 밀도를 조사한 결과는 다음과 같다. 라오스 찹쌀벼 품종의 볏짚 및 왕겨를 각각 기존 사용하고 있는 톱밥배지의 10, 20, 30, 40, 50, 60, 70, 80, 90%까지 각각 혼합처리 (V/V)하여 유리칼럼시험을 실시하여 균사의 생장과 밀도를 5일 간격으로 조사한 결과, 대조구 8.6cm/15일, 6.2cm/10일, 2.2cm/5일에 비하여 볏짚 및 왕겨를 각각 혼합함으로서 균사생장과 밀도가 현저히 좋았다. 볏짚 70%를 혼합하였을 때 13.5cm/15일, 8.8cm/10일, 3.2cm/5일로서 균사생장이 가장 좋았으며 균사밀도도 가장 높았다. 왕겨 40%, 50%를 혼합하였을 때 각각 10.1cm, 10cm/15일로서 균사생장과 밀도가 가장 좋았다. 볏짚과 왕겨의 비율을 2: 8, 4: 6, 5: 5, 6: 4, 8: 2로 각각 혼합처리(V/V)한 결과, 4 : 6의 혼합비율이 15일째에 각각 11.25cm로 가장 좋았고 다음이 5 : 5와 2 : 8비율이 좋았고, 6 : 4, 8 : 2 순으로 균사생장과 밀도가 대조구에 비하여 좋았다. 맥주박의 진흙 형 (S.T)과 효모 형 (Y.T)을 각각 10, 20, 30%까지 혼합처리 (V/V)한 결과, 균사생장은 두가지 형 모두 약간의 촉진효과가 있었고 균사밀도는 진흙 형보다 효모 형이 균일하게 좋았다.

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라오스의 변경 자본주의 대(대) 캄보디아의 세습 과두제 (Frontier Capitalism in the Lao PDR Versus Patrimonial Oligarchy in Cambodia)

  • 에도 안드리세
    • 한국경제지리학회지
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    • 제16권3호
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    • pp.408-422
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    • 2013
  • 논문은 최근의 학문적 성과들을 바탕으로 아시아 지역의 자본주의 다양성과 비즈니스 시스템에 대한 논의를 담고 있다. 본 논문의 목적은 참고 문헌들을 통해 국가의 역할과 경제 지리의 성격을 규명하여 라오스와 캄보디아의 자본주의적 다양성을 살펴보는 것이다. 따라서 영토가 경제 권력을 어떻게 재조직하는 요인으로 작용해왔는지에 대한 질문과 라오스와 캄보디아가 국가 자본주의와 베이징-서울-도쿄 합의에 의해 어떻게 변화하고 있는지에 대한 질문에 대답하고자 한다. 두 국가 간의 비교 분석은 라오스의 국가에 의해 조정되는 Frontier Capitalism과 캄보디아의 세습적 과두 체제 간의 차이를 규명한다. 라오스는 지역적으로 자본주의적 다양성이 발현된다. 공간적인 제약이 약한 캄보디아의 과두적 집권층은 상대적으로 시장의 기능에 주목하지만 기회의 균등이라는 면에서는 완전한 자유 시장을 지향하고 있지는 않다. 본 연구의 연구 결과들은 실증적, 이론적 두 가지 관점 모두에서 아시아의 자본주의에 대한 후속 연구의 가능성들을 제기한다. 향후의 연구는 중소 기업의 역할에 대해 고려해야 할 것이며 이론들은 과두제와 개인적, 가족적 자본주의를 통합하여야 한다.

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