• 제어로봇시스템학회:학술대회논문집
• /
• 1996.10a
• /
• pp.193-196
• /
• 1996

A pneumatic cylinder has been used in the production facilities of various industries. However, it is difficult to achieve deciding the precise position of the piston rod, due to the nonlinear properties arising from the air compression and the friction. In recent years, the fuzzy control algorithm has been frequently applied to various kinds of systems on account of its simple algorithm, good adaptability to complex or nonlinear systems and so on. On the other hand, the PID or I-PD control has been used in many engineering fields because of the excellent performance. However, it is known that each one of them has disadvantages. In this paper, we propose a hybrid control which is strived to obtain the advantages of each other. It is shown that the proposed hybrid control performs better than the conventional I-PD control through the experimental results.

• 제어로봇시스템학회:학술대회논문집
• /
• 1995.10a
• /
• pp.428-431
• /
• 1995

In this paper we propose an on-line tuning method by using genetic algorithm for robust minimax I-PD controller based on new criterion. The new criterion is the Integral of Squared Error (ISE) with a penalty of the derivative of manipulated variable. The work focuses on robust tuning of I-PD controller's parameters in the presence of plant parameter uncertainty. The result of several simulation studies are provided to illustrate the performance of this robust tunig method.

• Proceedings of the KIEE Conference
• /
• 2002.11c
• /
• pp.46-49
• /
• 2002

This paper presents I-PD controller design using LQR method in a two-inerita motor system to satisfy the design specification in time domain. And to provide a systematic LQ analysis for two-inerita motor system. The tuning parameters of LQ(I-PD) controller are determinated by the relationships between the design parameters of the overshoot and the settling time which are design specifications in time domain, and the weighting factors Q and R in LQR we can achieve the performance-robustness in time domain as well as the stability-robustness.

• 제어로봇시스템학회:학술대회논문집
• /
• 2000.10a
• /
• pp.483-483
• /
• 2000

The Fuzzy Preview Control (FPC) design methodology using I-PD Preview Control (IPC) and Optimal Preview Control (OPC)[6] are discussed in this paper. First we show a new fuzzy controller with single input single output, and build a relationship between it and the I-PD Control proposed by Kitamari, as well as Optimal Control with some specific equations. We also give the stability analysis with Lyapunov theorem. On this way, we can design a Fuzzy I-PD Controller (FIC) very easier and more effective. Then, preview control element design methodology of FCP was given according to IPC and OPC. Third, to make the system more rapidly and more little overshooting, two factors are given to adjust the controller's properties. At last, the performance of FPC is revealed via computer simulation using a nonlinear plant.

• Journal of the Korean Vacuum Society
• /
• v.6 no.2
• /
• pp.165-171
• /
• 1997

If the thickness of Pd deposited is larger than 9$\AA$, its phase is $Pd_3Si$. This phase is followed by pure Pd phase with further deposition of Pd. Also, when the thickness of Pd deposited on top of Si(111) is larger than 1$\AA$, the phase of Pd-silicide formed is found to be Pd2Si. The full width at half maximum of Pd 3d core-levels increases with decreasing of Pd film thickness at low coverages ($\leq0.5\AA$). This is due to the formation of additional phase of Pd silicide, i.e. PdSi, in addition to $Pd_2Si$.

• Physical Therapy Korea
• /
• v.14 no.2
• /
• pp.11-20
• /
• 2007

The development of neonatal neuromuscular system is accomplished by the functional interaction between the spinal neurons and its target cells, skeletal muscle cells, and the intrinsic and extrinsic factors affecting this process. The aim of this study was to identify the effect of suspension unloading (SU) and neuromuscular electrical stimulation (NMES) upon the development of the neonatal spinal cord. For this study, the neonatal rats were randomly divided into three groups: a control group, an experimental group I, and an experimental group II. The SU for experimental group I and II was applied from postnatal day (PD) 5 to PD 30, and the NMES for experimental group II was applied from PD 16 to PD 30 using NMES that gave isometric contraction with 10 Hz for 30 minutes twice a day. In order to observe the effect of SU and NMES, this study observed neutrophin-3 (NT-3) and microtubule associated protein 2 (MAP2) immunoreactivity in the lumbar spinal cord (L4-5) at the PD 15 and PD 30. The results are as follows. At PD 15, lumbar spinal cord of experimental group I and II had significantly lower NT-3 and MAP2 immunoreactivity than control group. It proved that a microgravity condition restricted the spinal development. At PD 30, lumbar spinal cord of control group and experimental group II had significantly higher NT-3 and MAP2 immunoreactivity than experimental group I. It proved that the NMES facilitated the spinal development by spinal cord-skeletal muscle interaction. These results suggest that weight bearing during the neonatal developmental period is essential for the development of neuromuscular development. Also, the NMES on its target skeletal muscle can encourage the development of the spinal cord system with a full supplementation of the effect of weight bearing, which is an essential factor in neonatal developmental process.

• Journal of Institute of Control, Robotics and Systems
• /
• v.8 no.3
• /
• pp.193-198
• /
• 2002

In this paper, we Propose a PD+I fuzzy controller using an error-accumulating applying factor. In fuzzy control, analytical study was done formerly, in which fuzzy control can be classified by PD type and PI type, and also the study for getting merits of both types was done, too. But the mixed type has a complex structure and many parameters. The proposed fuzzy controller is 2-input 2-out-put and PD type fuzzy control is used as a basic structure. And the proposed controller annihilates a steady-state error and improves transient responses because of using the error-accumulating applying factor which is determined in the real time along the current state of controlled process. Futhermore it is easy to tune the system because of decreasing the number of scaling factors and the I type controller with resetting resolves the integral wind-up problem. Finally we apply the proposed scheme to various plants and show the performance betterment.

• Korean Journal of Radiology
• /
• v.22 no.3
• /
• pp.366-375
• /
• 2021

Objective: To evaluate the radiological tumor response patterns and compare the response assessments based on immune-based therapeutics Response Evaluation Criteria in Solid Tumors (iRECIST) and RECIST 1.1 in metastatic clear-cell renal cell carcinoma (mccRCC) patients treated with programmed cell death-1 (PD-1) inhibitors. Materials and Methods: All mccRCC patients treated with PD-1 inhibitors at Henan Cancer Hospital, China, between January 2018 and April 2019, were retrospectively studied. A total of 30 mccRCC patients (20 males and 10 females; mean age, 55.6 years; age range, 37-79 years) were analyzed. The target lesions were quantified on consecutive CT scans during therapy using iRECIST and RECIST 1.1. The tumor growth rate was calculated before and after therapy initiation. The response patterns were analyzed, and the differences in tumor response assessments of the two criteria were compared. The intra- and inter-observer variabilities of iRECIST and RECIST 1.1 were also analyzed. Results: The objective response rate throughout therapy was 50% (95% confidence interval [CI]: 32.1-67.9) based on iRECIST and 30% (95% CI: 13.6-46.4) based on RECIST 1.1. The time-to-progression (TTP) based on iRECIST was longer than that based on RECIST 1.1 (median TTP: not reached vs. 170 days, p = 0.04). iRECIST and RECIST 1.1 were discordant in 8 cases, which were evaluated as immune-unconfirmed PD based on iRECIST and PD based on RECIST 1.1. Six patients (20%, 6/30) had pseudoprogression based on iRECIST, of which four demonstrated early pseudoprogression and two had delayed pseudoprogression. Significant differences in the tumor response assessments based on the two criteria were observed (p < 0.001). No patients demonstrated hyperprogression during the study period. Conclusion: Our study confirmed that the iRECIST criteria are more capable of capturing immune-related atypical responses during immunotherapy, whereas conventional RECIST 1.1 may underestimate the benefit of PD-1 inhibitors. Pseudoprogression is not rare in mccRCC patients during PD-1 inhibitor therapy, and it may last for more than the recommended maximum of 8 weeks, indicating a limitation of the current strategy for immune response monitoring.

• The Korean Journal of Mycology
• /
• v.25 no.3 s.82
• /
• pp.167-175
• /
• 1997

The PCR fragments of two distinct chitin synthase genes, PdCHSl and PdCHS2, were cloned from Penicillium diversum KCTC 6786. The nucleotide sequences of PdCHSl and PdCHS2 contained uninterrupted open reading frames (ORFs) of 570 bp excluding the primer sequence. The similarity analysis of the deduced amino acid sequences using BLASTP indicated that the possible evolutionary relationship between P. diversum and ascomycetous fungi. Multialignment of the deduced amino acid sequences of PdCHSs using CLASTAL W revealed that the PdCHSs fell into two different classes: PdCHSl into Class I and PdCHS2 into Class II of chitin synthase defined by Bowen et al. (1992). By Southern blot analysis, it was shown that each of the two genes is present as a single copy in the genome of P. diversum KCTC 6786.

• Analytical Science and Technology
• /
• v.9 no.3
• /
• pp.221-234
• /
• 1996

Basic studies for the effective extraction of dibenzylammonium dibenzyldithiocarbamate(DBADBDC) complexes of Ag(I), Pd(II), Au(III) and Pt(IV) into chloroform have been conducted. The effects of pH on the extraction of ligand itself and metal cemplexes showed that DBADBDC itself was uniformly extracted in the pH range of 2~9 and metal complexes were effectively extracted at the pH range as follows. That is, Ag(I) : in an acidic aqua medium, Pd(II) : > 4, Au(III) : wide range, and Pt(IV) : > 3. The distribution ratio and extractabilities were obtained from the partition and extraction equilibria of metal-DBDC complexes between aqueous solution and chloroform. Ag(I) : log D=4.226 : E(%)=99.9% in the aqueous solution of pH 0, Pd(II) : log D=1.804 : E(%)=98.5% at pH 4~7, Au(III) : log D=3.755 : E(%)=99.9% at pH 2~10, and Pt(IV) : log D=0.165 : E(%)=57.2% at pH 8.0. And also mole ratio of metal ion to ligand in complexes were determined by mole ratio method : 1 : 1 for Ag(I) and 1 : 2 for Pd(II), Au(III) and Pt(IV). $Cl^-$ was included as a coordination species in complexes of Au(III) and Pt(IV). Besides, extraction mechanisms of compleses sere examined in the presence of chloride ion in an aquous solution, and extraction reactions and estraction constants could be proposed and calculated, respectively.