• Journal of Life Science
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• v.21 no.4
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• pp.529-533
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• 2011

Metallothioneins (MT) are a group of low-molecular weight, cysteine-rich, intracellular proteins that are encoded by a family of genes containing at least 10 functional isoforms in human. The expression and induction of these proteins is associated with protection against DNA damage, oxidative stress, and apoptosis. Many studies have shown increased expression of MT in various human tumors, whereas MT is down-regulated in certain tumors such as hepatocellular carcinoma and liver adenocarcinoma. Hence, the expression of MT is not universal to all human tumors but may depend on the differentiation status and proliferative index of tumors, along with other tissue factors and gene mutations. Using Northern blot analysis, we found that laminin induced expression of MT-1 in HSG and PC12 cells, which can be differentiated by laminin, but had no effect on MB-231, MDA-435, and PC-3 cells, which cannot be differentiated by laminin. In addition, we analyzed the expression level of the MT-1 gene in five prostate cancer cell lines possessing different metastatic potential. The expression of MT-1 in normal and less malignant cells (RWPE-1 and WPE1-NA22) was high and up-regulated by laminin, whereas the expression of MT-1 in WPE1-NB14, WPE1-NB11, and WPE1-NB26 cells (malignant) was extremely low and not elevated by laminin. These results suggest that the MT-1 gene is involved in laminin-mediated differentiation and affects the metastatic potential of tumor cells.

• Journal of Physiology & Pathology in Korean Medicine
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• v.35 no.6
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• pp.242-248
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• 2021

This study aims to compare nail-fold capillary blood velocity (CBV) according to the presence or absence of cold hypersensitivity in the hands (CHH) using nail-fold capillaroscopy under cold stress conditions. Eleven participants were taken from the cohort study for observing long-term health status of the faculty of Semyung university. Seven of the participants displayed CHH while four showed signs of non-CHH. CBV between 0 and 60 seconds (S1) and between 240 and 300 seconds (S2) was measured under cold stress for 5 minutes, respectively, and the average value was used to compare non-CHH group and CHH group. Body mass index, Nogung (PC8) temperature and temperature difference between Nogung (PC8) and Hyeopbaek (LU4) were significantly lower in CHH group compared to non-CHH group. The S2-S1 CBV difference was negatively correlated with PC8 temperature and PC8-LU4 temperature, and positively correlated with cold pattern score and cold hypersensitivity visual analog scale. The CHH group had a lower CBV overall than non-CHH group, and the S2-S1 CBV difference was significantly higher in the CHH group than in non-CHH group. This study suggests that CBV measured by nail-fold capillarosopy might be a useful indicator of cold hypersensitivity properties.

• Journal of the Korean Institute of Landscape Architecture
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• v.19 no.2
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• pp.12-22
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• 1991

The purpose of this study is to identify demand and methods of projection, including to prove the variables affecting the fluctuation of visitors and to analyze the relationship between these variables in National Park. Statistical analysis method (Multiple Linear Regression Analysis, ANOVA, and Model diagnostics) was carried out by computer program SAS/pc. 13 variables (1. Total Population, 2. Per Capita PDI, 3. Employment Ratio of S.O.C. & others, 4. NO. of Passenger Car, 5. Length of Roads, 6. Leisure Expenditure of Farm Household, 7. Leisure Expenditure of Urban Household, 8. Price Index, 9. NO. of Bus, 10. Exchange on Dollars, 11. Export, 12. Import, and 13. Visitors in National Park) had been used to this study. The scope of time period is during the last 17 years (1970-1986). The results were as follows; 1) Participation depends only on the specific characteristics of the economic factors (Price Index and Leisure Expenditure of Urban Household). These factors are the importance factors directly affecting the participation of visitors. The statistical Model for projecting the visitors in National Parks is the function of "Visitors in National Parks (thousand)=14915+0.210311*Leisure Expenditure of Urband Household (won)-157.835619*Price Index(1985=100)" 2) The external factors affecting the participation depends upon the interelated features of availability and accessibility (NO. of Passenger Car, Length of Roads, and NO. of Bus) of recreation resources or sites, and the economic factors (Per Capita PDI, Export, and Import). These factors are the factors indirectly affecting the participation of visitors. 3) The participation depends on the specific characteristics of demographic factors (Total Population and Employment Ratio of S.O.C. & others). These factors are the factors indirectly affecting the participation of visitors. 4) The unexpected fluctuation of yearly visitors depends on oil shock or inflation (1971, 1973-1974, 1979-1980), promulgation of national emergency decrees (1971-1972, 1974-1975, 1979-1980), and national events (assassination of president Park's wife, Madame Yuk in 1974 and president Park I 1979).

• Child Health Nursing Research
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• v.7 no.2
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• pp.213-224
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• 2001

This study was conducted to identify the effect on the weight control of the REBT group program as a nursing intervention. For this purpose, non-equivalent control group design with pretest and posttest and follow-up test as quasi-experiment was used. Subjects of the study were consisted of twenty-four obese girls (Experimental group: 10, control group: 14) who appeared to having above 20％ of the body mass index from ane high school in M city. The whole program was carried out from January to June, 2000. Used dependent variables for evaluating the effect of the REBT group program including were weight control belief(rational thinking, emotion about exercise, eating self-efficacy, eating behavior), body mass index and serum lipids(total cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein). For evaluating the effect of the program, dependent variables was analyzed by experimental stages three times; the first week, the fourth week, and the eighth week since the experimental input began. Data were analyzed by the SAS PC＋ program with t-test, repeated measure ANOVA to determine the effect of program. The results of this study can be summarized as follows; 1. After the REBT group program, only eating self-efficacy among the weight control belief of experimental group was significantly increased than that of control group. 2. After the REBT group program, body mass index of experiment group was significantly decreased than that of control group. 3. After the REBT group program, triglyceride and low density lipoprotein among the serum lipids in the experiment group were significantly decreased than those of control group.

• Journal of muscle and joint health
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• v.5 no.1
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• pp.7-25
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• 1998

Rheumatoid arthritis, unlike other chronic diseases, causes the patients to experience uncertainty in their daily lives and thus to feel threat on their emotional comfort because of inconsistent and unpredictable symptoms such as pain. Therefore, a theoretical framework is needed for explanation of uncertainty in patients having rheumatoid arthritis. A hypothetical model was constructed on the basis of Mishel's Uncertainty Theory and other literature review. The model included 9 theoretical concepts and 19 paths. Subjects of the study constituted 330 partients who visited outpatient clinics of two university hospitals and one general hospital in Seoul. Self report questionnaires were used to measure the variables affecting uncertainty. Reliability coefficients of these instruments were found Cronbach's Alpha=$.70{\sim}.94$. In data analysis, SAS program and PC-LISREL 8.03 computer program were utilized for descriptive statistics and covariance structure analysis. The results of covariance structure analysis for model fitness were as follows : 1) Hypothetical model showed a good fit to the empirical data : Chi-square($X^2$)=41.81 (df=11, P=.000), Goodness of Fit Index=.974, Root Mean Square Residual=.049, Normed Fit Index=.928, Non Normed Fit Index=.814. 2) For the validity and the parcimony of model, a modified model was constructed by appending 2 paths and deleting 5 paths according to the criteria of statistical significance and meaningfulness. 3) The results of hypothesis testing were as follows : (1) Educational level, event familiarity and severity of illness had a direct effect on uncertainty : Event congruency had both direct and indirect effect on uncertainty : Credible authority and symptom consistency had a nonsignificant direct effect on uncertainty, (2) Illness duration, symptom consistency, and event congruency had a direct effect on severity of illness ; Credible authority had a both direct and indirect effect on severity of illness ; Event congruency had the greatest effect on severity of illness, and event familiarity had a nonsignificant direct effect on severity of illness.

• PNF and Movement
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• v.10 no.1
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• pp.1-7
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• 2012

Purpose : To verify the interrater reliability of upper extremity function assessment among three tools(Wolf motor function test, Motor assessment scale, Fugl-meyer assessment scale). Methods : The subjects of this study 40 (20 was physical therapists and 20 was physical therapy students). For the test one patients with chronic hemiparesis after stroke participated in the study. The Wolf Motor Function Test consists of 16 functional tasks. The motor assessment scale consists of 3 functional tasks. The fugl-meyer assessment scale consists of 8 functional tasks. All test sessions were videotaped and scored by 40 subjects. Analysis : The data was analysis by SPSS PC 14.0 with Cronbach alpha Coefficients, intraclass Correlation Coefficients Kendall tau-b value. Results : WMFT was highly scored in Cronbach's value, Cronbach's ${\alpha}=0.819$ that means high interrater reliability among assessment. WMFT was highly scored all items in p-value except one item, that means high p-value between therapists and students. WMFT was highly scored in Intrarater correlation coefficient (ICC) = 0.79, that means high interrater reliability of each examination item. WMFT was low index of coincidence from all items, MAS was low index of coincidence from a tim and FMA was low index of coincidence from 4 items. Conclusion : The interrater reliability of WMFT were compared with MAS, FMA and highly verified. WMFT can be more useful tool among upper extremity function assessment.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2003.05a
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• pp.107-110
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• 2003

본 연구에서는 EEG를 이용하여 정신집중 시, 뇌 기능의 변화를 알아보았다. 실험은 건강한 남녀 고교생 9명을 대상으로 EEG는 Fp1. Fp2, F3, F4, P3, P4, T5, T6, O1, O2의 10위치에 대하여 정신집중 작업 진의 3분과 작업 시 30분간을 측정하였다. 작업은 PC를 이용하였으며 모니터 상의 움직임에 집중하고 목표자극을 탐지하였을 때 신속하게 적절한 반응키를 누르도록 하였다. 각 주파수 대역은 theta2와 (6.0-8.0Hz), alpha1파 (8.0-10.0Hz), alpha2파(10.0-12.0Hz)로 구분하였으며 비대칭지수를 이용하여 분석하였다. 그 결과, 정신집중 작업 시 theta1, theta2, alpha1대역에서 두정엽의 우반구과 측두엽 및 후두엽의 좌반구영역이 우세하였다. 이들 영역은 시갈, 지각, 움직임 기능을 수행하며 theta2파가 주의, alpha1파가 각성 관련이다. 이상의 결과에서 두정엽의 우반구와 측두엽 및 후두엽의 좌반구영역의 theta1파, theta2파, alpha1파가 정신집중 작업 시 중요한 역할을 담당하는 것으로 나타났다.

• Women's Health Nursing
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• v.14 no.2
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• pp.150-155
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• 2008

Purpose: The purpose of this study was to verify the effect of aromatherapy program on lowering body mass index and serum estrogen in obese post-menopause women. Method: One group Pretest-posttest experimental design was used. All subjects received intervention of aromatherapy program. The participants used 3% grapefruit oil, cypress and three other kinds of oil. BMI and Serum estrogen level of the participants' were measured by ZEUS 9.9(Resource Medical, 2004) and PACKARD Gamma Counter-Cobra II RI Manual(USA, 1997) before and after interventions being applied at the P. hospital. Data were analyzed by paired t-test using the SPSS/PC+Win 12 Version. Result: The level of serum estrogen and BMI of the participants were significantly decreased after aromathetapy program. Conclusion: These results suggest that the effect of aromatheapy program could be utilized as an effective intervention to reduce BMI and serum estrogen level in obese post-menopause women.

• Journal of the Korean Solar Energy Society
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• v.23 no.1
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• pp.68-75
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• 2003

본 논문에서는 파랑, 녹색, 호박색 빨강색, 백색 등 고휘도 5mm LED(light emitting diode)의 기본적인 분광분포(SED: spectral energy distribution) 특성을 분석하였으며, LED램프의 중요한 광학 특성인 광속, 효율 피크 파장$({\lambda}p)$, 가중치 평균 파장, 반치폭(FWHM, $\Delta\lambda$), 색도좌표, 주 파장, 자극순도(Pe)와 휘도순도(Pc) 등을 측정 및 실험하였다. 제시된 LED램프의 특성 데이터는 앞으로 LED램프를 사용한 새로운 조명등기구를 개발하는데 많은 도움을 줄 것이며, 이러한 측정 데이터들은 조명용 광원으로서 LED램프의 사용 대체 가능성을 나타낸다.

• Journal of Korean Public Health Nursing
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• v.21 no.1
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• pp.67-74
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• 2007

Purpose: The purpose of this study was to research the distorted self-perception of body image held by many college students. Method: The subjects in this study consisted of 189 female college students and 125 male college students. The data were obtained through self-reported questionnaires completed by the students between April 1 and April 10, 2005. The data were analyzed by frequency and a $x^2$-test in the SPSS/pc 10.0 statistical program. Result: While female students tend to perceive themselves as being more overweight than they actually are according to their BMI scores, male students consider themselves to be thinner than they actually are according their BMI scores. Conclusion: Many female and male college students have a distorted self-perception of body weight. These findings indicate that health care providers need to do a better job of educating college students about normal body weight.