• Annual Conference of KIPS
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• 2003.11a
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• pp.45-48
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• 2003

수중 음원의 식별은 수중전에서 매우 중요한 요소이다. 수중 음원의 식별을 위해 신호의 획득, 처리 및 분석과 청음훈련을 지원할 수 있는 시스템을 개발하였다. 실제 사용되고 있는 다양한 종류의 소나(SONAR) 장비 상호간 및 육상 지원 장비간의 호환성 문제와 경제성을 고려하여 PC기반 체계로 개발하였다. 개발된 시스템은 선박별 장치별 음파의 특징 추출이 가능하며 개별 장치의 특징이 두개이상 복합적으로 나타날 때에도 가능하다.

• Annual Conference of KIPS
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• 2013.05a
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• pp.254-256
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• 2013

기존의 음성기반 감정인식 기술은 충분한 컴퓨팅 파워를 가진 PC에서 수백개의 특징을 사용하여 감정을 인식하고 있다. 이러한 음성기반 감정인식 기술은 컴퓨팅 파워에 제약이 많은 스마트폰 환경을 고려하지 않은 방법이다. 본 논문에서는 제한된 스마트폰 컴퓨팅 파워를 고려한 음성의 특징 추출 기법과 서버 클라이언트 개념을 도입한 효율적인 음성기반 감정인식 프레임워크를 제안한다.

• Korean Journal of Pharmacognosy
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• v.40 no.4
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• pp.351-356
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• 2009

Many isoquinoline alkaloids including berberine lower dopamine content by reducing tyrosine hydroxylase (TH) activity and aggravate L-DOPA-induced cytotoxicity in PC12 cells. In this study, the effects of berberine on 6-hydroxydopamine (6-OHDA)-induced cytotoxicity in PC12 cells and on unilateral 6-OHDA-lesioned rat models were investigated. Berberine at 10-30 ${\mu}M$ did not affect cell viability in PC12 cells. However, berberine at concentrations higher than $50{\mu}M$ caused cytotoxicity at 24 h. Berberine (10-50 ${\mu}M$) also enhanced 6-OHDA (10-50 ${\mu}M$)-induced cytotoxicity at 24 h compared to 6-OHDA alone with an apoptotic process. In addition, treatment with berberine (5 and 30 mg/kg, i.p.) for three weeks showed a dopaminergic cell loss in substantia nigra of 6-OHDA-lesioned rats: 30 mg/kg berberine was more intensive cytotoxic. The levels of dopamine were also decreased by berberine (5 and 30 mg/kg) in the ipsilateral substantia nigra of 6-OHDA-lesioned rats. These results suggest that berberine aggravated 6-OHDA-induced cytotoxicity in PC12 cells and treatment with berberine (5 and 30 mg/kg) in 6-OHDA-lesioned rats also enhanced the degeneration of dopaminergic cell death and the decrease in dopamine levels in substantia nigra. Therefore, the long-term L-DOPA therapeutic patients with isoquinoline compounds including berberine may need to be checked for the adverse symptoms.

• Applied Biological Chemistry
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• v.37 no.4
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• pp.287-294
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• 1994

New 3-phenyl-1-(2-furyl)propenones, 1 and 3-phenyl-1-(2-furyl)-3-thiophenyl-propanone, 2 derivatives were synthesized, and their fungicidal activities in vitro against Botrytis cineria (BC), Valsa ceratosperma (VC), Scelerotium cepivorum (SC) and Phytophthora capsici (PC) were investigated using a generalized structure-activity relationship (SAR). The activity of 1 was superior to those of 2, and nonsubstituent, 1a and chloro group substituent, 1d of E (Syn) conformer were the most effective $(EC_{50}=10{\sim}12\;ppm)$ compound to BC. Antifungal activities were able to predict to depend essentially on the ${\beta}$ carbon and their positive charge from the results that the good correlation $(r^2=0.90)$ was observed between hydrolysis rate constant (logk) of 1 and the electronic parameter $({\sigma})$ of X-substituent on the ${\beta}-phenyl$ ring.

• Journal of the Institute of Electronics Engineers of Korea TE
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• v.39 no.2
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• pp.76-83
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• 2002

In this paper, we developed the real-time automation program for the immunity test according to the determination of the EUT image, and analyzed the image of standard PC monitor and the monitor image affected by the electromagnetic field. The image change detection algorithm was realized for the real-time determination of the malfunction, and we attempted to obtain the consistent results for the electromagnetic immunity measurement. We showed the possibility to determine the immunity of the PC monitor and other equipment by performing the image change detection of EUT, and the experimental results for the EUT immunity determination of EMS (Electro-Magnetic Susceptibility, IEC 61000-4-3) are also proposed in line with the international standard and domestic trends. 

• Macromolecular Research
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• v.11 no.5
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• pp.334-340
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• 2003

In order to fabricate new sustained delivery device of nerve growth factor (NGF), we developed NGF-loaded biodegradable poly(L-lactide-co-glycolide) (PLGA, the mole ratio of lactide to glycolide 75:25, molecular weight: 83,000 and 43,000 g/mole, respectively) film by novel and simple sandwich solvent casting method for the possibility of the application of neural tissue engineering. PLGA was copolymerized by direct condensation reaction and the molecular weight was controlled by reaction time. Released behavior of NGF from NGF-loaded films was characterized by enzyme linked immunosorbent assay (ELISA) and degradation characteristics were observed by scanning electron microscopy (SEM) and gel permeation chromatography (GPC). The bioactivity of released NGF was identified using a rat pheochromocytoma (PC-12) cell based bioassay. The release of NGF from the NGF-loaded PLGA films was prolonged over 35 days with zero-order rate of 0.5-0.8 ng NGF/day without initial burst and could be controlled by the variations of molecular weight and NGF loading amount. After 7 days NGF released in phosphate buffered saline and PC-12 cell cultured on the NGF-loaded PLGA film for 3 days. The released NGF stimulated neurite sprouting in cultured PC-12 cells, that is to say, the remained NGF in the NGF/PLGA film at 37 $^{\circ}C$ for 7 days was still bioactive. This study suggested that NGF-loaded PLGA sandwich film is released the desired period in delivery system and useful neuronal growth culture as nerve contact guidance tube for the application of neural tissue engineering.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.36T no.4
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• pp.9-16
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• 1999

We suggest the image recognition algorithm for automatic decision of EUT malfunction using computer vision in the radiant electromagnetic field. We monitor and analyze the EUT malfunction through the numerical value change of electro-measurement and medical instruments, or the image distortion of PC monitor. We could decide EUT malfunction by comparing the object image in the electromagnetic field with the reference image or by recognizing the numerical value change on the video camera monitor. We can show the evidence of EUT malfunction decision and reduce the possibility of malfunction in the tolerance test.

• Bulletin of the Korean Chemical Society
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• v.27 no.8
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• pp.1149-1153
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• 2006

LPC analogues including natural and unnatural LPC, 3-L-2-PC, acetylated LPC and ethylene glycol derivative are prepared from D-mannitol using in convenient procedures by only changing the synthetic sequences, and their protective activities against cecal ligation and puncture (CLP)-induced severe sepsis are compared. The chirality at C2 position in LPC is found to be required as (S)-configuration for sepsis inhibition, comparing from the protection activity between LPC 6 and unnatural LPC 8. The hydroxyl functionality is also very important and required at C2 or C3 position as shown in the protection activities of ethylene glycol analogue 11 and 3-L-2-PC 9.

• Journal of the Semiconductor & Display Technology
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• v.8 no.4
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• pp.77-82
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• 2009

In robot operation, a motor with multi-degree of freedom motion control and an encoder for motor control are needed. To perform precise motion, location, and velocity control, the operation of motor and encoder with superior performance is important. In this paper, we studied performance evaluation system that can evaluate the performance of motor and encoder. The performance of motor and encoder can be evaluated in terms of disconnection check, signal variation count, and U, V, W signal check. Disconnection check verifies signal connection between a motor and an encoder, signal variation check verifies A, B signal by counting the number of signal A, B when a motor revolves, and U, V, W signal check verifies operating direction of a motor. The result is shown at graphic LCD integrated in system, and can be checked in PC with PC communication.

• Journal of Life Science
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• v.22 no.11
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• pp.1552-1557
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• 2012

It has been reported that pipernonaline isolated from Piper longum Linn. has a wide biochemical and pharmacological effect, including antitumor activity in prostate cancer PC-3 cells. However, its mechanism and expression pattern of many genes involved in biological functions are not clearly understood. To perform the gene expression study in PC-3 cells treated with pipernonaline, a cDNA microarray chip composed of 44,000 human cDNA probes was used. As a result, cell cycle-related genes, apoptosis-related genes, and cell proliferation/growth-related genes have been identified in gene ontology of the DAVID database. These results suggest that pipernonaline has antitumor activity by regulating the expression pattern of genes involved in biological signaling pathway in prostate cancer PC-3 cells. Further, additional analysis of these microarray data can be a useful tool to identify the mechanism and discovery of novel genes in cancer therapy.