• 제목/요약/키워드: PARs

검색결과 138건 처리시간 0.025초

대기중 다환 방향족 탄화수소류의 분석에 관한 연구 (A Study on the Analysis of Polycyclic Aromatic Hydrocarbons in Air)

  • 표희수;홍지은;이강진;박송자;이원
    • 분석과학
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    • 제13권4호
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    • pp.453-465
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    • 2000
  • 환경중 다환 방향족 탄화수소류(PAHs)는 유기물의 연소중의 열합성에 의해서 주로 발생하며 강한 발암성물질로 알려져 있다. 또한 도시 대기중의 PAHs는 주로 자동차 배기가스 및 주택연료의 불완전연소에 의해서 발생하는 것으로 알려져 있으며, 국내에서도 자동차의 수요 급중과 도시난방의 서구화에 따라 도시 대기중 PAHs의 증가가 우려되며 이에따라 대기중 PAHs의 인체 위해성 평가가 시급한 실정이다. 본 연구에서는 위해성 평가를 위한 기초 조사로서 1996년 4월부터 1997년 1월가지 1년에 4차례에 걸쳐 서울을 비롯한 6대 도시 14개 지역에서의 대기중의 23종의 PAHs농도를 측정하였다. 분석 결과 총 263종의 거의 모든 시료에서 14종의 PAHs가 검출되었으며 1년간 총 PAHs의 평균 농도는 $28.72ng/m^3$이었고, 겨울철(평균 $47.76ng/m^3$)에 가장 높은 농도로 검출되었다. 각 시료에서 추출된 총 유기물질(EOM ; Exoacted Organic Material)과 총 PAHs 농도는 대체로 비례하였으며 EOM에 함유된 총 PAHs는 평균 0.28%로 조사되었다. 본 실험 결과 PAH의 위해성 평가가 수행되어야 할 것으로 기대되며 계절별 시료 분석을 지속적으로 수행하여 보다 신뢰성 있는 데이타 구축이 필요하다.

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불완전 XML을 위한 파싱 방법 (A Parsing Method for an Incomplete XML)

  • 조경룡;조성언;박장우
    • 한국정보통신학회논문지
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    • 제12권12호
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    • pp.2153-2158
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    • 2008
  • 대표적인 웹 문서의 표준인 XML은 문서의 구조와 내용을 기술하기 위해 태그로 이루어진 문법 구조를 갖는다. XML 문서 작성자는 XML 문서 작성 중 해당 XML DTD(Document Type Definition)에 문법적으로 올바르지 않은 문장을 입력할 수 있다. 즉, 일반적인 텍스트 에디터 환경에서 XML 문서에 입력되는 내용과 태그의 쌍은 완전하지 못한 형태로 입력될 수 있다. 문법적으로 불완전한 문장 입력은 사용자의 계속적인 편집 상태를 종료하고, 정상적인 파싱을 보장하지 않는 원인이 된다. XML 문서를 작성하는 과정에서 문법적으로 불완전한 문장 입력은 정상적인 파싱을 보장하지 않는다. 따라서, 에디터가 문법적으로 빠져있는 부분의 심볼이 무엇인지 정확히 인식 가능하고, 주어진 문법에 따라 부분적인 파스트리를 완성한다면, 사용자의 프로그래밍 편집 상태를 종료하지 않고 계속적인 편집과 성공적인 파싱을 보장할 수 있을 것이다. 본 논문은 XML 문서 편집기에 사용될 수 있는 XML 파서가 문법적으로 불충분한 문장의 입력에 대해 문법에 따라 빠진 부분을 인식하고, 누락된 문법 심벌을 찾아 부족한 부분 파스트리를 완성함으로써 사용자에게 성공적인 XML 문서 편집을 보장할 수 있는 파싱 방법을 제안한다. 제안된 파싱 방법을 통해 사용자는 프로그래밍 편집 중 문법 오류에 대한 부담을 줄일 수 있다. 또한, 사용자는 불완전 입력에 대해 일반적인 에러 처리에 따른 편집 중단 없이 계속적인 문서 파싱 을 보장받아 편집 효율을 높일 수 있다.

유리체절제술과 수정체유화술 동시 수술 시 백내장수술 후 앞방내 에피네프린 주입과 동공 확대 (Intracameral Epinephrine Injection after Phacoemulsification on Pupil Dilation during Phacovitrectomy for Proliferative Diabetic Retinopathy)

  • 김상범;박종엽;신재령;이승우
    • 대한안과학회지
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    • 제59권12호
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    • pp.1137-1141
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    • 2018
  • 목적: 증식당뇨망막병증에서 유리체절제술과 수정체유화술을 동시에 시행한 경우 백내장수술 후 에피네프린 앞방내 주사가 동공 확대에 미치는 영향에 대해 알아보고자 하였다. 대상과 방법: 증식당뇨망막병증에서 유리체절제술과 수정체유화술을 동시에 시행한 96명(96안)에서 백내장수술 후 0.001% 에프네프린을 앞방내 주사를 한 군(주사군, 46안)과 하지 않은 군(대조군, 50안)에서 수술 전, 백내장수술 후, 유리체절제술이 끝난 후 동공 크기를 비교하였다. 동공 크기는, 저장된 수술 동영상에서 Image J 프로그램(National Institute of Health, Bethesda, MD, USA)을 이용하여 동공면적과 각막면적의 비를 구하여 수술 전-백내장수술 후의 동공 크기의 변화와 백내장수술 후-유리체절제술 후의 동공의 크기 변화를 비교하였다. 결과: 주사 군에서 수술 전 동공/각막면적의 비는 $0.52{\pm}0.11$, 백내장수술 후에는 $0.43{\pm}0.12$, 유리체절제술 후에는 $0.51{\pm}0.11$로 통계학적으로 유의한 동공 크기 변화를 관찰할 수 있었다(p<0.001, p<0.001). 대조군에서 수술 전 동공/각막면적의 비는 $0.52{\pm}0.10$, 백내장수술 후에는 $0.39{\pm}0.15$, 유리체절제술 후에는 $0.43{\pm}0.15$였다. 대조군에서는 백내장수술 후에는 동공 크기가 유의하게 차이가 났으나(p=0.011), 유리체절제술 후에는 유의한 동공 크기의 차이를 관찰할 수가 없었다(p=0.056). 결론: 에피네프린 앞방내 주사는 증식당뇨망막병증 환자에서 유리체절제술과 초음파유화술 병합 수술 시 백내장수술 후 동공을 다시 빠르게 산동시킬 수 있는 간단한 처치 방법으로 생각된다.

1-methyl-4-phenylpyridinium으로 유도된 신경 손상에 대한 quercetin-3-O-glucuronide의 보호 효과 (Protective Effects of Quercetin-3-O-glucuronide against 1-methyl-4-phenylpyridinium-induced Neurotoxicity)

  • 파리야르라메스;바스또라통킹;서정원
    • 생명과학회지
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    • 제29권2호
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    • pp.191-197
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    • 2019
  • 파킨슨병은 운동완서, 근육경직, 진전 및 비정상적인 자세 등을 임상적 특징으로 하는 주로 운동 신경계에 영향을 주는 진행성 신경 퇴행성 질환이다. 파킨슨병은 산화 스트레스와 세포 내 신호 전달 경로의 조절 장애에 의한 뇌 흑색치밀부에서의 도파민성 신경세포의 사멸을 특징으로 한다. Quercetin의 주요 대사산물인 Quercetin-3-O-glucuronide (Q3GA)는 신경 보호 효과가 있는 것으로 보고 되어 왔다. 본 연구에서는 SH-SY5Y 세포에서 1-methyl-4-phenyl pyridinium ($MPP^+$)에 의해 유도된 신경 독성에 대한 Q3GA의 신경 보호 효과와 그 분자 조절 기전을 조사하였다. Q3GA는 $MPP^+$에 의해 유도된 세포 사멸을 유의적으로 감소시켰으며 PARP 절단을 감소시켰다. 또한, Bax/Bcl-2 비율의 감소와 함께 $MPP^+$에 의해 증가된 세포 내 ROS를 감소시켰다. Q3GA는 $MPP^+$에 의해 감소된 Akt와 CREB의 인산화를 유의적으로 회복시켰지만, ERK에는 영향을 미치지 않았다. 이 결과는 Q3GA가 ROS 생산 억제와 Akt/CREB 신호 전달 경로를 통해 $MPP^+$ 에 의해 유도된 신경 독성을 억제시킬 수 있음을 시사한다. 본 연구는 Q3GA가 파킨슨병에 대한 예방제 또는 치료제로 개발될 수 있는 가능성을 제시한다.

MPTP로 유도된 Parkinson's disease 동물 모델에서 항염증효과를 통한 측백엽의 도파민신경보호 효과 (Thuja orientalis leaves extract protects dopaminergic neurons against MPTP-induced neurotoxicity via inhibiting inflammatory action)

  • 박건혁;김효근;주미선;김애정;오명숙
    • 대한본초학회지
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    • 제29권3호
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    • pp.27-33
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    • 2014
  • Objectives : The aim of this study was to investigate the protective effect of extract of Thuja orientalis leaves (TOFE) against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity by inhibition of inflammation in in vitro and in vivo models of Parkinson's disease (PD). Methods : We evaluated the effect of TOFE against lipopolysaccharide (LPS)/1-methyl-4-phenylpyridinium ($MPP^+$) toxicity using nitric oxide (NO) assay, inducible NO synthase and cyclooxygenase 2 western blot, tyrosine hydroxylase and microglia activation immunohistochemistry (IHC) in BV2 cell, primary rat mesencephalic neurons, or C57BL/6 mice. We also evaluated the effect of TOFE in mice PD model induced by MPTP. C57BL/6 mice were treated with TOFE 50 mg/kg for 5 days and were injected intraperitoneally with four administrations of MPTP on the last day. We conducted behavioral tests and IHC analysis to see how TOFE affect MPTP-induced neuronal loss of dopaminergic neurons in substantia nigra pars compacta (SNpc) and striatum (ST) of mice. To assess the anti-inflammation effects, we carried out glial fibrillary acidic protein and macrophage-1 antigen integrin alpha M in IHC in SNpc and ST of mice. Results : In an in vitro system, TOFE decreasesd NO generations in BV2 cells. TOFE protected dopaminergic cells against LPS or $MPP^+$-induced toxicity in primary mesencephalic dopaminergic neurons. In vivo system, TOFE at 50 mg/kg treated group showed improved motor deteriorations than the MPTP only treated group and TOFE significantly protected striatal dopaminergic damage from MPTP-induced neurotoxicity in mice. Moreover, TOFE inhibited activation of astrocyte and microglia in SNpc and ST of the mice. Conclusions : We concluded that TOFE showed anti-parkinsonian effect by protection of dopaminergic neurons against MPTP toxicity through anti-inflammatory actions.

Empirical correlation for in-situ deformation modulus of sedimentary rock slope mass and support system recommendation using the Qslope method

  • Yimin Mao;Mohammad Azarafza;Masoud Hajialilue Bonab;Marc Bascompta;Yaser A. Nanehkaran
    • Geomechanics and Engineering
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    • 제35권5호
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    • pp.539-554
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    • 2023
  • This article is dedicated to the pursuit of establishing a robust empirical relationship that allows for the estimation of in-situ modulus of deformations (Em and Gm) within sedimentary rock slope masses through the utilization of Qslope values. To achieve this significant objective, an expansive and thorough methodology is employed, encompassing a comprehensive field survey, meticulous sample collection, and rigorous laboratory testing. The study sources a total of 26 specimens from five distinct locations within the South Pars (known as Assalouyeh) region, ensuring a representative dataset for robust correlations. The results of this extensive analysis reveal compelling empirical connections between Em, geomechanical characteristics of the rock mass, and the calculated Qslope values. Specifically, these relationships are expressed as follows: Em = 2.859 Qslope + 4.628 (R2 = 0.554), and Gm = 1.856 Qslope + 3.008 (R2 = 0.524). Moreover, the study unravels intriguing insights into the interplay between in-situ deformation moduli and the widely utilized Rock Mass Rating (RMR) computations, leading to the formulation of equations that facilitate predictions: RMR = 18.12 Em0.460 (R2 = 0.798) and RMR = 22.09 Gm0.460 (R2 = 0.766). Beyond these correlations, the study delves into the intricate relationship between RMR and Rock Quality Designation (RQD) with Qslope values. The findings elucidate the following relationships: RMR = 34.05e0.33Qslope (R2 = 0.712) and RQD = 31.42e0.549Qslope (R2 = 0.902). Furthermore, leveraging the insights garnered from this comprehensive analysis, the study offers an empirically derived support system tailored to the distinct characteristics of discontinuous rock slopes, grounded firmly within the framework of the Qslope methodology. This holistic approach contributes significantly to advancing the understanding of sedimentary rock slope stability and provides valuable tools for informed engineering decisions.

요추 후방 감압술에서 발생한 후천적 척추분리증과 척추전방전위증의 다중검출 전산화단층촬영 소견 (Multidetector CT Findings of Acquired Spondylolysis and Spondylolisthesis after Posterior Lumbar Laminectomy)

  • 윤혜인;황지영;유정현
    • 대한영상의학회지
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    • 제81권3호
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    • pp.644-653
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    • 2020
  • 목적 이 연구는 요추 후방감압술에서 발생한 후천적 척추분리증과 척추전방전위증의 다중검출 전산화단층촬영 소견에 대해 분석하고자 하였다. 대상과 방법 2003년부터 2017년까지 요추 후방감압술을 시행 받고 수술 전 및 수술 후 다중검출 전산화단층촬영을 촬영한 74명의 환자를 대상으로 하였다. 유합술을 시행하지 않은 1군과 유합술을 시행한 2군의 환자로 분류하였다. 수술 후 다중검출 전산화단층촬영 영상에서 요추 후방감압술의 크기, 척추분리증 또는 척추전방전위증 유무와 위치, 척추전방전위증의 유무, 후방관절 및 척추주위 근육의 지방 변화에 대해 분석하였다. 결과 후천적 척추분리증 또는 척추전방전위증의 빈도는 1군에서 20명 중 4명, 2군에서 54명 중 2명이였다. 후방감압술의 크기(%)는 전체 추궁판에 대한 추궁절제술의 크기를 백분율로 계산하였다. 요추 후방감압술의 크기(%)는 후천적 척추분리증 또는 척추전방전위증이 있는 경우 54.0 (1군)과 53.2 (2군)이었고, 후천적 척추분리증과 척추전방전위증이 없는 경우는 35.0(1군)이었다. 척추분리증의 위치는 1군에서는 후방감압술 분절의 후관절 부근에서 발생하며, 2군에서는 유합술 하방의 관절 간부에 발생하였다. 결론 다중검출 전산화단층촬영은 요추 후방감압술 이후 후천적 척추분리증과 척추전방전위증을 진단하는 데 유용하고, 후천적 척추분리증의 전형적인 위치를 잘 보여준다. 요추 후방감압술의 크기가 클수록 후천적 척추분리증과 척추전방전위증의 발생과 연관이 있었다.

관절염환자(關節炎患者)의 특성(特性)에 대한 조사(調査) 연구(硏究) (A Research in the Characteristic of Arthritis Patienth)

  • 강점덕;남철현;김기열
    • 대한예방한의학회지
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    • 제1권1호
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    • pp.149-165
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    • 1997
  • In order that, investigating the feature of patients suffering arthritis, analysing its contents, and grasping a Primary factor affecting it, I might offerbasic datas which could help to plan and perform healthy affairs to thake precautions beforehand, I have investigated, analysed, and studied a total of 320 patients suffering arthritis, who have received physiotherapy in hospital located in Teaegu area for five months, from November 1 1995 to March 30 1996, of which summary and conclusion is this. 1. The general feature of patients in investigative objects In the distribution of the distinction of sex, men accounted for 26.9% and women, for 73.1%, and, in the fistribution of age, 60-year-old or more, most for 27.2% and from 20 to 29 years old, least for 14.0%. In the distinction of a vocation, housewives most accounted for 34.7% and students(jobless men), least for 19.3%. In the distinction of a matrimonial state, married persons most accounted for 76.7% and people living alone(divorce, separation by death, separation), least for 11.4%. In the distinction of an economic state, the middle classes most accounted for 73.5% and the upper classes, least for 2.9%. In the distinction of their academic careers, graduates of a primary school most accounted for 26.9% and graduates of university, for 14.1%, of which patients, having the ability to decode the national language, reached to 11.3%. In the distinction of the house form, people living in independent houses most accounted for 76.4% and residents in apartment(having an elevator), least for 9.4%. 2. In the distribution of the recurring state in the distinction of the feature, the recurring group was more than the group of patients falling that ill at first as 62.2% and in the distinction of the feature of the recurring group, the recurring group turned high in case of men being from 50s to 60s years old or more, people living alone (divorce, separation by death, separation), students (joblessmen), people working in farming, stockbeeding, forestry, fisheries, a simple labour, graduates of a primary school I having the ability to decode the national language, the upper classes, people part two years since they begined to suffer arthritis, people who had members having ever experienced arthritis among families. 3. In the distribution of arthritis on the distinction of bodily pars, a knee articulation most accounted for 50.2% and the articulation of fingers, for 8.8%, wile the simultaneous, several parts (multiple) accounted for 35.1%. In the distinction of the feature, arthritis of a knee turned high in case of men being from 20s to 30s years old, unmarried persons, people having academic careers of university, the middle classes, residents in apartment (having stairs). In the dictnction of a feature the case of several parts (multiple) turned high in case of women being from 50s to 60s years old or more, people living alone (divorce, separation by death, separation), people having the ability to decode th. national language, the graduates of a primary school, the upper classes, residents in apartment (having elevator). 4. In the distribution of arthritis on e distinction of a contracting term, two years or more most accounted for 51.6% and the case of contacting from one year to two years, for 15.3%. Analysing the distinction of the feature, the case of two years or more turned high in case of women being from 50s to 60s years old or more, people living alone (divorce separation by death, separation), the upper classes, people having the ability to decode the national language, residents in apartment (having elevator). 5. In the distribution of an treatment institution before patients came to help, their not curing most accounted for 39.1%, general, orthopedic, neurological surgery (physical therapy), for. 20.0%, and th. therapy of Chinese medicine (acupuncture, moxacautery, Chinese medicine), for 17.5%, and a pharmacy (medical therapy), for 13.4%. The case of patients not curing, in the distinction of a feature, turned high in case of men 20s years old, unmarried, the lower classes, people having academic careers of university, residents in apartment (having elevator). 6. In e distribution of the extent of satisfaction with treatment, common most accounted for 54.4% and some satisfaction, for 32.8%. The case of common, in the distinction of a feature, turned high, in case of men living alone from 50s to 60s years old (divorce, separation by death, separation), married persons, the upper classes, people having academic careers of university, residents in independent house, residents in apartment (having elevator), 7. In the distribution of the degree of knowledge of the cause of arthritis, patients knowing that the cause is to use very much a articulation in normal times most accounts for 60.1%, and patients knowing the state of short nutrition as a cause, for 2.5%. The case of patients knowing that the cause is to use very much in normal times, in the distinction of a feature, turned high in·case of ment being 20s and 60s years old or more, unmarried persons, e lower classes, people having the ability to decode. the national language, people having academic careers of university, residents in apartment (having stairs), 8. In the distribution of the state of physical exercise before arthritis contracted, patients exercising very much on the whole most accpimend for 40.3%, and patients not exercising, for 34.7%. The case of patients exercising very much on the whole, in the distinction of the feature, turned high in case of men being from 50s to 60s years old or more, people living alone(divorce, separation by death, separation), the lower classes, people having the ability to decode the national language, graduates of a primary school, residents in apartment (having elevator). 9. In the taste of patients suffering from arthritis, while the group of patients falling that ill at first and the recurring group didn't smoke cigarets, during alcohol and coffee on the whole, and the group of patients falling once again that ill drank a cup of distilled linquor and three cup of coffee or more on the whole per one day, and the group of patients falling that ill at first liked sort of vegetables and the recurring group liked very much sons of vegetables and fresh and meat in their loving food normal times. 10. Analysing the distribution on the dining table used by patients and the structure of a powder room, at first, in the structure of a powder room, the group of patients filling that ill have a toilet stool using as their sits, and a Bush toilet on the whole, and the recurring group, a toilet stool using as their sits and conventional type, and in the structure of a dinning table, the group of patients falling that ill at first and the recurring group turned high, each as 66.9% and 6.3%, who have a dining table carring here and there. 11. In the distribution of patients of arthritis in relation to stress, the case that they feeled severly symptoms of arthritis when thay got stress, turned high, each, as 78.6% in the recurring poop, and the case not knowing, as 61.5% in the first group. In the extent of stress normal times, the case that they got much stress on the whole turned high, each, as 72.4% in e recurring group, and the care that got less stress on the whole, as 60.0%. 12. In the distribution on the distinction of symptoms and impedimental extent, the recurring group turned high in each variable. Analysing the feature of the recurring group, in the distinction of symptoms, the case that they fooled much that the node of an articulation is stiff, turned high, as 71.6, and in the distinction of treatment before. patients came to helpk, the theraphy of Chinese medicine (physical theraphy), as 84.4%, the theraphy of Chinese medicine (acupuncture, moxacautery, Chinese medicine), as 73.2%, and in the distinction of the satisfing extent on treatment, the case of comman, as 72.3%, and in the cause of arthritis, the case not recruiting their health after a birth, as 68.5%, and the case not recovering wholely an articulation having got hurt, as 62.8%, and in the state of physical exercise before they begined suffering from arthritis, the case exercising very much on the whole, (as 74.2%), and in the extent of subjective impediment, the case of not being able to act almost, as 66.7%, the case of acting but feeling some hard, as 66.3%. 13. The correlation in variables in relation to arthritis Analysing realted variables, the recurring frequency showed correlation with such as the extent that patients got stress normal times, and the exercising state before suffering arthritis, and showed contra-correlation with academic careers, the wights, coffee. The cigaret, e loving food of taste, showed corralation with the weight, stature, alcohole as the loving food of taste. On the basis of this result medical members of heal, who are related to the regular education, public education or development of this program, should be concerned to prevent orthris.

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