• Title/Summary/Keyword: PAR index

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Characterization of the Brain Transport and Brain-to-Blood Efflux of Nitrone Based Antioxidant, PBN (Nitrone계 항산화제 (PBN)의 뇌에서 혈액으로의 배출과 뇌 수송 특성)

  • 이나영;강영숙
    • YAKHAK HOEJI
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    • v.47 no.4
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    • pp.224-229
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    • 2003
  • We have investigated the transport characteristics of synthetic antioxidant and free radical scavenger, $\alpha$-phenyl-n-tert-butyl nitrone (PBN) at the blood-brain barrier (BBB) by in vitro uptake study in conditionally immortalized rat brain capillary endothelial cell line (TR-BBB). Also, the efflux of PBN from brain to blood is estimated using the brain efflux index (BEI) method. Choline is a charged organic cation, including nitrogen-methyl group and shows the carrier-mediated distribution to the brain. [$^3$H]Choline uptake by TR-BBB cells was significantly inhibited by PBN with $IC_{50}$/ of 1.2 mM, which appears to be due to similar structures between choline and PBN. And, PBN was microinjected into Par2 of the rat brain by BEI method, and was eliminated from the brain with an apparent elimination half-life of about 2 min. Also, [$^3$H]choline efflux was significantly inhibited by PBN using BEI method. In conclusion, the efflux transport of PBN takes place across the BBB and PBN may be transported into the brain and eliminated from the brain by BBB choline transporter.

Determination of Seed Purity in Radish (Raphanus sativus L.) Using Allozyme (알로자임에 의한 무 씨의 순수성 검증)

  • Huh, Man-Kyu
    • Journal of Life Science
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    • v.18 no.7
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    • pp.907-911
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    • 2008
  • Radish (Raphanus sativus L.) is one of very important crop plants in the world. It is very important to determine hybrid seed quality in the production of hybrid Brassica vegetable seeds to avoid unacceptable contamination with self-inbred (sib) seeds. The allozyme for evaluating seed purity in a commercial $F_1-hybrid$ radish cultivar is demonstrated. Three hundred sixty seeds from the male and female harvest were subsequently screened for seed purity using 27 isozyme loci. Especially, F1 hybrids of radish, Per-1 ($aa{\times}bb$), Lap-1 ($aa{\times}bb$), Est-1 ($aa{\times}bb$) were presented clear hybrid bands. Est-1 locus revealed that 15 (8.3%) seeds from the female harvest and 26 (14.4%) seeds from the male harvest were sibs. It maintains higher than average level of genetic diversity compared with their correspondent parents. Shannon's index of phenotypic diversity (I) of hybrids was the highest of all accessions (R. sativus L. cv. Daepeng, R. sativus L. cv. Backza, and their hybrids). The allozyme may lead to a better insight into the hybrid seed purity.

The Improvement of maintainability evaluation method at system level using system component information and fuzzy technique (시스템의 구성품 정보와 퍼지 기법을 활용한 시스템 수준 정비도 평가 방법의 개선)

  • Yoo, Yeon-Yong;Lee, Jae-Chon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.3
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    • pp.100-109
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    • 2019
  • Maintainability indicates the extent to which maintenance can be done easily and quickly. The consideration of maintainability is crucial to reduce the operation and support costs of weapon systems, but if the maintainability is evaluated after the prototype production is done and necessitates design changes, it may increase the cost and delay the schedule. The evaluation should verify whether maintenance work can be performed, and support the designers in developing a design to improve maintainability. In previous studies, the maintainability index was calculated using the graph theory at the early design phase, but evaluation accuracy appeared to be limited. Analyzing the methods of evaluating the maintainability using fuzzy logic and 3D modeling indicate that the design of a system with good maintainability should be done in an integrated manner during the whole system life cycle. This paper proposes a method to evaluate maintainability using SysML-based modeling and simulation technique and fuzzy logic. The physical design structure with maintainability attributes was modeled using SysML 'bdd' diagram, and the maintainability was represented by an AHP matrix for maintainability attributes. We then calculated the maintainability using AHP-based weighting calculation and fuzzy logic through the use of SysML 'par' diagram that incorporated MATLAB. The proposed maintainability model can be managed efficiently and consistently, and the state of system design and maintainability can be analyzed quantitatively, thereby improving design by early identifying the items with low maintainability.

Evolution Trends of Biotite and Hornblende in Granitic Rocks from Yonghae-Yongdok Area, Northeastern Gyeongsang Basin, Korea (경상분지(慶尙盆地) 북동부(北東部) 영해(盈海)·영덕일대(盈德一帶)의 화강암질암(花崗岩質岩)의 흑운모(黑雲母)와 각섬석(角閃石)의 진화경로(進化經路))

  • Lee, Yoon-Jong;Kim, Joong-Wook;Chung, Won-Woo
    • Economic and Environmental Geology
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    • v.26 no.3
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    • pp.349-361
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    • 1993
  • The granitic rocks in the study area are divided into the schist and gneiss complex, Yongdok pluton, Yonghae pluton and Onjong pluton by their texture, fabric and relationship to the adjacent rocks in the field, Schist and gneiss complex occurs as xenolith or roof pendant in the Yongdok, Yonghae and Onjong plutons. The Yongdok pluton occurs in association with pegmatite and aplite in many places of its pluton. In the field it is obviously clarified that the Yongdok pluton is unconformably overlay by the Cretaceous sedimentary rocks. The Yonghae and Onjong plutons are gradationally changed each other, and these plutons truncate both the Yongdok pluton and the Cretaceous sedimentary rocks. Petrographically, the Yongdok pluton consists of granodiorite and granite with minor quartz monzonite. The Yonghae pluton is composed of diorite, quartz diorite, tonalite, and granodiorite. The Onjong pluton also ranges granodiorite to granite. Both the Yongdok and Yonghae-Onjong plutons are different in the constituent minerals, such as alkali feld~par, myrmekite, mica, sphene and mafic minerals. This suggests that each pluton might have been different crystallization sequence and characteristically different gological history during the crystallization period. Iron/magnesium ratio in biotite and hornblende from both the Yongdok and Yonghae-Onjong plutons gradually decrease as the differentiation index increasing in the whole rock. The decrease of this ratio strongly depend on the increase of opaque mineral contents. From the results of chemistry in the whole rocks and some mafic minerals, it is suggest that the granite plutons of the two different geological ages would have been suffered the environment of high oxygen fugacity in the process of magmatic emplacement and during the crystallization period.

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Capability Assessment on Meteorological Technology - Comparative Study of Technological Prowess on Korea, U.S., and Japan - (국가 기상기술력 수준 평가 - 한국, 미국, 일본을 대상으로 한 비교 연구 -)

  • Kim, Se-Won;Park, Gil-Un;Cho, Changbum;Lee, Young-Gon;Yim, Deok-Bin
    • Atmosphere
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    • v.21 no.3
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    • pp.319-336
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    • 2011
  • The objective of this study was to assess the meteorological capability of Korea by comparing with that of the U.S. and Japan as of 2010. The research was conducted based on various indices and surveys, and quantified the results using the Gordon's scoring model. The index assessment used 11 items derived from 9 segments - surface observation, advanced observation and observations quality in the observation field; data assimilation, numerical model and infrastructure in the data processing field; forecast accuracy in the forecast field; climate prediction and climate change in the climate field - in this research, we classified the meteorological technology into four fields. In the survey assessment, another 10 items in addition to the above 11 ones (total 21 items) were used. In the field of climate, Korea was found to lag far behind the U.S. (96.5p) and Japan (90.5p) with 77.6 points out of 100, which is 18.9 and 12.9 points lower than them respectively. On the other hand, Korea showed the narrowest gap with Japan (95.3p) and the U.S. (94.2) in the forecasting field, recording 90.3 points. Particularly, in surface observation, infrastructure and forecast accuracy segment, Korea was on a par with the U.S. and Japan, boasting 100.5 percent compared to their counterparts. However, in advanced observation, data quality and climate change segment, Korea was only at the level of 81.5 percent compared to that of the U.S. and Japan. All in all, the technological prowess of Korea, scoring 84.6 points, stood at 89.7 percent of that of the U.S. (94.3p) and 91.9 percent of Japan (92.1p).

The objective and quantitative analysis of malocclusion - Part 2. Influence of malocclusion components to treatment difficulty (부정교합의 객관적 정량분석: Part 2. 부정교합 요소들의 치료난이도에 미치는 영향)

  • Joo, Bo-Hoon;Lee, Ki-Soo
    • The korean journal of orthodontics
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    • v.35 no.1 s.108
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    • pp.69-81
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    • 2005
  • As one of the variations in growth and development of the craniofacial complex. malocclusion shows lack of concordance In the recognition and severity of malocclusion for dentists as well as the acceptance and need of orthodontic treatment for the patient The purposes of this study were 1) to examine the relationships between objective malocclusion severity aid subjective treatment difficulty. 2) to evaluate the effect of malocclusion components to the subjective perceived difficulty of treatment. 3) to establish the weighted values of malocclusion components to reflect the treatment difficulty 100 pairs of dental casts with the general characteristics of malocclusion. were selected from the orthodontic departments of Kyunghee University and Samsuug Medical Center. The severity of malocclusion was evaluated by the author with the PAR index The perceived treatment difficulty and the estimated treatment duration on these dental models were evaluated by 8 experienced orthodontists. The relationships between the objective malocclusion severity and the subjective treatment difficulty were statistically evaluated. and the weighted values of malocclusion components to reflect treatment difficulty were statistically formulated. There were significant relationships between objective malocclusion severity and subjective treatment difficulty The malocclusion components which significantly affected the treatment difficulty and their weighted values in parentheses were as follows upper anterior alignment(1). overbite (2). buccal occlusion (3) middline (4), and overjet (5). This study Provides the fundamental principle to evaluate the objective malocclusion severity which is reflected by the subjective treatment difficulty of Korean orthodontists.

On Using Near-surface Remote Sensing Observation for Evaluation Gross Primary Productivity and Net Ecosystem CO2 Partitioning (근거리 원격탐사 기법을 이용한 총일차생산량 추정 및 순생태계 CO2 교환량 배분의 정확도 평가에 관하여)

  • Park, Juhan;Kang, Minseok;Cho, Sungsik;Sohn, Seungwon;Kim, Jongho;Kim, Su-Jin;Lim, Jong-Hwan;Kang, Mingu;Shim, Kyo-Moon
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.23 no.4
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    • pp.251-267
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    • 2021
  • Remotely sensed vegetation indices (VIs) are empirically related with gross primary productivity (GPP) in various spatio-temporal scales. The uncertainties in GPP-VI relationship increase with temporal resolution. Uncertainty also exists in the eddy covariance (EC)-based estimation of GPP, arising from the partitioning of the measured net ecosystem CO2 exchange (NEE) into GPP and ecosystem respiration (RE). For two forests and two agricultural sites, we correlated the EC-derived GPP in various time scales with three different near-surface remotely sensed VIs: (1) normalized difference vegetation index (NDVI), (2) enhanced vegetation index (EVI), and (3) near infrared reflectance from vegetation (NIRv) along with NIRvP (i.e., NIRv multiplied by photosynthetically active radiation, PAR). Among the compared VIs, NIRvP showed highest correlation with half-hourly and monthly GPP at all sites. The NIRvP was used to test the reliability of GPP derived by two different NEE partitioning methods: (1) original KoFlux methods (GPPOri) and (2) machine-learning based method (GPPANN). GPPANN showed higher correlation with NIRvP at half-hourly time scale, but there was no difference at daily time scale. The NIRvP-GPP correlation was lower under clear sky conditions due to co-limitation of GPP by other environmental conditions such as air temperature, vapor pressure deficit and soil moisture. However, under cloudy conditions when photosynthesis is mainly limited by radiation, the use of NIRvP was more promising to test the credibility of NEE partitioning methods. Despite the necessity of further analyses, the results suggest that NIRvP can be used as the proxy of GPP at high temporal-scale. However, for the VIs-based GPP estimation with high temporal resolution to be meaningful, complex systems-based analysis methods (related to systems thinking and self-organization that goes beyond the empirical VIs-GPP relationship) should be developed.

Estimation of Nitrogen Uptake and Biomass of Rice (Oryza sativa L.) Using Ground-based Remote Sensing Techniques (지상 원격측정 센서를 활용한 벼의 생체량과 질소 흡수량 추정)

  • Gong, Hyo-Young;Kang, Seong-Soo;Hong, Soon-Dal
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.5
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    • pp.779-787
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    • 2011
  • This study was conducted to evaluate the usefulness of ground-based remote sensing for the estimation of rice yield and application rate of N-fertilizer during growing season. Dongjin-1, Korean cultivar of rice was planted on May 30, 2006 and harvested on October 9, 2006. Chlorophyll content and LAI (leaf area index) were measured using Minolta SPAD-502 and AccuPAR model LP-80, respectively. Reflectance indices were determined with passive sensors using sunlight and four types of active sensors using modulated light, respectively. Reflectance indices and growth rate were measured three times from 29 days to 87 days after rice plating and at harvesting day. The result showed that values of growing characteristics and reflectance indices were highly correlated. Growing characteristics to show significant correlation with reflectance indices were in order of followings: fresh weight > N uptake > dry weight > height > No. of tiller > N content. Chlorophyll contents measured by chlorophyll meter (SPAD 502) showed high correlation with nitrogen concentration (r=$0.743^{**}$), although the correlation coefficients between remote sensing data and nitrogen concentration were higher. LAI was highly correlated with dry weight (r=$0.931^{**}$), but relationship between LAI and nitrogen concentration (r=$0.505^*$) was relatively low. The data of CC-passive sensor were negatively correlated with those of the near-infrared. NDVI correlation coefficients found more useful to identify the growth characteristics rather than data from single wavelength. Both passive sensor and active sensor were highly significantly correlated with growth characteristics. Consequently, quantifying the growth characteristics using reflectance indices of ground-based remote sensing could be a useful tool to determine the application rate of N fertilizer non-destructively and in real-time.

Measurements of Isoprene and Monoterpenes at Mt. Taehwa and Estimation of Their Emissions (경기도 태화산에서 isoprene과 monoterpenes 측정 및 배출량 산정)

  • Kim, Hakyoung;Lee, Meehye;Kim, Saewung;Guenther, Alex.B.;Park, Jungmin;Cho, Gangnam;Kim, Hyun Seok
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.17 no.3
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    • pp.217-226
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    • 2015
  • To investigate the distributions of BVOCs (Biogenic Volatile Organic Compounds) from mountain near mega city and their role in forest atmospheric, BVOCs and their oxidized species were measured at a 41 m tower in Mt. Taehwa during May, June and August 2013. A proton transfer reaction-mass spectrometer (PTR-MS) was used to quantify isoprene and monoterpenes. In conjunction with BVOCs, $O_3$, meteorological parameters, PAR (Photosynthetically Active Radiation) and LAI (Leaf Area Index) were measured. The average concentrations of isoprene and monoterpenes were 0.71 ppbv and 0.17 ppbv, respectively. BVOCs showed higher concentrations in the early summer (June) compared to the late summer (August). Isoprene started increasing at 2 PM and reached the maximum concentration around 5 PM. In contrast, monoterpenes concentrations began to increase 4 PM and stayed high at night. The $O_3$ maximum was generally found at 3 PM and remained high until 5 PM or later, which was concurrent with the enhancement of $O_3$. The concentrations of BVOCs were higher below canopy (18 m) than above canopy, which indicated these species were produced by trees. At night, monoterpenes concentrations were negatively correlated with these of $O_3$ below canopy. Using MEGAN (Model of Emissions of Gases and Aerosols from Nature), the emissions of isoprene and monoterpenes were estimated at 1.1 ton/year and 0.9 ton/year, respectively at Mt. Taehwa.