• Clinical and Experimental Reproductive Medicine
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• v.50 no.3
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• pp.192-199
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• 2023

Objective: This study was conducted to investigate chromosomal abnormalities and their correlations with clinical and radiological findings in females with primary amenorrhea (PA). Methods: Detailed forms were recorded for 470 females, including the construction of three-generation pedigrees. Peripheral venous blood was drawn, with informed consent, for cytogenetic analysis. Results: An abnormal karyotype was found in 16.38% of participants. The incidence of structural abnormalities (6.8%) exceeded that of numerical abnormalities (6.15%). Turner syndrome represented 45% of all numerical abnormalities. Furthermore, the Y chromosome was detected in 5% of females with PA. Among the structural chromosomal abnormalities detected (n=32) were mosaicism (25%), deletions (12.5%), isochromosomes (18.75%), fragile sites (3.12%), derivatives (3.12%), marker chromosomes (3.12%), and normal variants (29.125%). An examination of secondary sexual characteristics revealed that 29.6% of females had a complete absence of breast development, 29.78% lacked pubic hair, and 36.88% exhibited no axillary hair development. Radiological findings revealed that 51.22% of females had a hypoplastic uterus and 26.66% had a completely absent uterus. Abnormal ovarian development, such as the complete absence of both ovaries, absence of one ovary, one absent and other streak, or both streak ovaries, was observed in 69.47% of females with PA. Additionally 43.1%, 36.1%, 67.4%, and 8% of females had elevated levels of serum follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, and prolactin, respectively. Conclusion: This study underscores the importance of karyotyping as a fundamental diagnostic tool for assessing PA. The cytogenetic correlation with these profiles will aid in genetic counseling and further management of the condition.

• Korean Journal of Radiology
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• v.22 no.10
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• pp.1619-1627
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• 2021

Objective: This study used cardiac magnetic resonance imaging (MRI) to compare the characteristics of left ventricular remodeling in patients with primary aldosteronism (PA) with those of patients with essential hypertension (EH) and healthy controls (HCs). Materials and Methods: This prospective study enrolled 35 patients with PA, in addition to 35 age- and sex-matched patients with EH, and 35 age- and sex-matched HCs, all of whom underwent comprehensive clinical and cardiac MRI examinations. The analysis of variance was used to detect the differences in the characteristics of left ventricular remodeling among the three groups. Univariable and multivariable linear regression analyses were used to determine the relationships between left ventricular remodeling and the physiological variables. Results: The left ventricular end-diastolic volume index (EDVi) (mean ± standard deviation [SD]: 85.1 ± 13.0 mL/m² for PA, 75.9 ± 14.3 mL/m² for EH, and 77.3 ± 12.8 mL/m² for HC; p = 0.010), left ventricular end-systolic volume index (ESVi) (mean ± SD: 35.2 ± 9.8 mL/m² for PA, 30.7 ± 8.1 mL/m² for EH, and 29.5 ± 7.0 mL/m² for HC; p = 0.013), left ventricular mass index (mean ± SD: 65.8 ± 16.5 g/m² for PA, 56.9 ± 12.1 g/m² for EH, and 44.1 ± 8.9 g/m² for HC; p < 0.001), and native T1 (mean ± SD: 1224 ± 39 ms for PA, 1201 ± 47 ms for EH, and 1200 ± 44 ms for HC; p = 0.041) values were higher in the PA group compared to the EH and HC groups. Multivariable linear regression demonstrated that log (plasma aldosterone-to-renin ratio) was independently correlated with EDVi and ESVi. Plasma aldosterone was independently correlated with native T1. Conclusion: Patients with PA showed a greater degree of ventricular hypertrophy and enlargement, as well as myocardial fibrosis, compared to those with EH. Cardiac MRI T1 mapping can detect left ventricular myocardial fibrosis in patients with PA.

• Journal of Power System Engineering
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• v.7 no.2
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• pp.56-60
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• 2003

Recently the plastic fuel tube is usually used to reduce production cost and weight in automobiles. These days, material used to plastic fuel tube is the polyamide12. The fuel tube is made of the PA12. Post deformation of the tube has been changed by environmental temperature. So, it is important to prevent post deformation. The experiment is performed to investigate post deformation of the tube produced by each bending process. In this study, the results we obtained are used to bending process system for post deformation as the environmental temperature of the tube. It turned out that the method of steam heating and air cooling was shown less deformation than other methods.

• Journal of the Korean Vacuum Society
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• v.12 no.1
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• pp.7-15
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• 2003

Spinning Rotor Gauge (SRG) has been used to transfer standard gauge for international comparison at the high vacuum standards. We calibrated a spinning rotor gauge by using dynamic calibration system (DCS) that was a national high vacuum standards system. And its uncertainties were evaluated with the International Organization for Standardization (ISO), they were recognized ai A type uncertainty, B type uncertainty, combined Standard uncertainty, and expanded uncertainty. The combined standard uncertainties were $1.8007\times10^{-5}$ Pa ~ ~$4.8422\times10^{-5}$ Pa for this spinning rotor gauge.

• Journal of Biosystems Engineering
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• v.26 no.5
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• pp.409-414
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• 2001

This paper reports a technique for measuring a three-dimensional soil deformation and a simplified method to determine the three-dimensional contact area of agricultural tires in a soil bin. A Pirelli 12.4R28 radial-ply tire was used on soft soil. Effects of dynamic load and inflation pressure were determined using the equipment for measuring soil deformation on the soil surface. Soil deformation measurements were made under three conditions of over-load (59kPa-14.2kN), rated-load (108kPa-11.8kN) and under-load (157kPa-9.3kN) in the combinations of the inflation pressures (kPa) and the tire load (kN). The results from three conditions were shown that the contact area of the over-load increased considerably bigger than those of the rated-load and the under-load. Therefore, to regulate soil deformation, the inflation pressure and the tire load should be set according to the soil conditions.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.255-261
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• 2014

Essential fatty acid (EFA) is known to be required for the body to function normally and healthily. However, the effect of EFA on glucose uptake in skeletal muscle has not yet been fully investigated. In this study, we examined the effect of two EFAs, linoleic acid (LA) and ${\alpha}$-linolenic acid (ALA), on glucose uptake of C2C12 skeletal muscle cells and investigated the mechanism underlying the stimulatory effect of polyunsaturated EFAs in comparison with monounsaturated oleic acid (OA). In palmitic acid (PA)-induced insulin resistant cells, the co-treatment of EFAs and OA with PA almost restored the PA-induced decrease in the basal and insulin-stimulated 2-NBDG (fluorescent D-glucose analogue) uptake, respectively. Two EFAs and OA significantly protected PA-induced suppression of insulin signaling, respectively, which was confirmed by the increased levels of Akt phosphorylation and serine/threonine kinases ($PKC{\theta}$ and JNK) dephosphorylation in the western blot analysis. In PA-untreated, control cells, the treatment of $500{\mu}M$ EFA significantly stimulated 2-NBDG uptake, whereas OA did not. Phosphorylation of AMP-activated protein kinase (AMPK) and one of its downstream molecules, acetyl-CoA carboxylase (ACC) was markedly induced by EFA, but not OA. In addition, EFA-stimulated 2-NBDG uptake was significantly inhibited by the pre-treatment of a specific AMPK inhibitor, adenine 9-${\beta}$-D-arabinofuranoside (araA). These data suggest that the restoration of suppressed insulin signaling at PA-induced insulin resistant condition and AMPK activation are involved at least in the stimulatory effect of EFA on glucose uptake in C2C12 skeletal muscle cells.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.5
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• pp.722-726
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• 1996

To bring out the functional properties of Agar-agar extracted with 0.01N $H_2SO_4$ from Cellidium amansii produced in Che-ju Udo and its rheological properties were investigated. The flow behavior indexes in the range of $0.5\~5\%$ agar-agar solution were $0.62\~0.69\;at\;80^{\circ}C,\;0.46\~0.67\;at\;60^{\circ}C\;and\;0.34\~0.64\;at\;50^{\circ}C$. The consistency indexes were $0.12\~1.26\;Pa{\cdot}s^n\;at\;80^{\circ}C,\;0.12\~7.28\;Pa{\cdot}s^n\;at\;60^{\circ}C\;and\;3.9\~19952.6\;Pa{\cdot}s^n\;at\;50^{\circ}C$. Consistenry index's existence nature to concentration is two straight line relation which have different slopes on the border of $2\%$ concentration of agar-agar solution and existence nature of temperature followed Arrhenius equation. And the activation energy, in the range of $0.5\%\~5\%$ agar-agar solution, were $0.09\~13.51\;kcal/g{\cdot}mol$.

• The korean journal of orthodontics
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• v.45 no.4
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• pp.171-179
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• 2015

Objective: To compare dentoalveolar and skeletal changes produced by the pendulum appliance (PA) and the distal screw appliance (DS) in Class II patients. Methods: Forty-three patients (19 men, 24 women) with Class II malocclusion were retrospectively selected for the study. Twenty-four patients (mean age, $12.2{\pm}1.5years$) were treated with the PA, and 19 patients (mean age, $11.3{\pm}1.9years$) were treated with the DS. The mean distalization time was 7 months for the PA group and 9 months for the DS group. Lateral cephalograms were obtained at T1, before treatment, and at T2, the end of distalization. A Mann-Whitney U test was used for statistical comparisons of the two groups between T1 and T2. Results: PA and DS were equally effective in distalizing maxillary molars (4.7 mm and 4.2 mm, respectively) between T1 and T2; however, the maxillary first molars showed less distal tipping in the DS group than in the PA group ($3.2^{\circ}$ vs. $9.0^{\circ}$, respectively). Moreover, significant premolar anchorage loss (2.7 mm) and incisor proclination ($5.0^{\circ}$) were noted in the PA group, whereas premolar distal movement (1.9 mm) and no significant changes at the incisor ($0.1^{\circ}$) were observed in the DS group. No significant sagittal or vertical skeletal changes were detected between the two groups during the distalization phase. Conclusions: PA and DS seem to be equally effective in distalizing maxillary molars; however, greater distal molar tipping and premolar anchorage loss can be expected using PA.

• Journal of Oral Medicine and Pain
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• v.19 no.2
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• pp.233-244
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• 1994

The purpose of this study was to evaluate the gene frequency in parotid salivary proteins according to salivary blood components and salivary blood types. Parotid and whole saliva were collected from 160 healthy Korean adults (from 20 years of age to 43). They were divided by blood type(Q,B, AB,O type). Each group contained 40 adults respectively. They were tested to the salivary secretory blood components and parotid acidic protein(Pa), proline-rich protein(Pr) and double band protein(Db) were analyzed to evaluate the distribution of phenotype using alkaline slab polyacrylamide gel electrophoresis. Results were as follows : 1. In parotid saliva, the salivary blood substances were not found. In whole saliva, secretory type was 21.9% and non-secretory type was 78.1%. : In A type blood group, secretory type 87.5% and non-secretory type 12.5%. In B type blood group, secretory type 82.5% and non-secretory type 17.5%. In AB type blood group, secretory type 85% and non-secretory type 15%. In O type blood group, secretory type 57.5% and non-secretory type 42.5%. 2. The gene frequency of parotid acidic protein(Pa) were Pa+=0.160, Pa-=0.840 and proline-rich protein(Pr) were Pr1=0.781, Pr2=0.219 and double-band protein(Db) were Db+=0.019, Db-=0.981. 3. The difference between phenotype of Pa, Pr, Db proteins and salivary secretory blood components was not statistically significant. (P>0.05) 4. The difference between phenotype of Pa, Pr, Db proteins and blood types was not statistically significant.(P>0.05)

• Journal of muscle and joint health
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• v.29 no.3
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• pp.218-227
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• 2022

Purpose: This study aimed to describe the current level of physical activity (PA) and to explore the relationships between self-efficacy for PA, perceived health status (PHS), attitudes toward aging, ego-integrity and PA in community-dwelling older Koreans. Methods: A total of 164 participants were recruited from community centers, churches, and senior welfare centers in Korea. With questionnaires, a survey was conducted from June 3rd to 22th, 2016. Data were analyzed with descriptive statistics, independent t-test, one-way ANOVA and Pearson's correlation coefficient using SPSS/WIN 22.0 program. Results: The mean amount of total PA was 5,295.33±6,272.38 MET/min/week. The number of subjects engaged in vigorous, moderate, and low-intensity activities were 87 (53.0%), 45 (27.4%), and 32 (19.5%), respectively. Overall, physical activities were different according to the presence of spouse (t=-2.79, p=.006) and the presence of housemate (t=2.03, p=.044). The mean scores of self-efficacy for PA, PHS, attitudes towards aging, and ego-integrity were 17.16±4.45, 9.00±2.41, 68.12±9.28 and 51.62±7.59, respectively. There were significant positive correlations between overall PA and self-efficacy for PA (r=.34, p<.001), PHS (r=.23, p=.003), attitudes towards aging (r=.26, p=.001). Conclusion: Specific programs to promote physical activities in addition to continuous education for improving self-efficacy for PA, PHS, and attitudes towards aging in community-dwelling older adults are needed.