• 제목/요약/키워드: P2X7r

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중부지방 자생 비목나무 분포에 관한 연구 (A Study on the Native Distribution of Lindera erythrocarpa Makino in Central Korea)

  • 이동철
    • 한국자원식물학회지
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    • 제8권2호
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    • pp.175-182
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    • 1995
  • This study was carried out to investigate the check shelling distribution of Lindera erythrocarpa Makino in Kanghwa Island, MT. Suri, Kyunggido and MT. Kaya, Chungchongnamdo. The results were as follows : The total distribution area of Linedra erythrocarpa where are Jeondeung temple and Jugsu temple Kanghwa Island, MT. Suri, Kyunggido and MT. Kaya, Chungchongnamdo was 344.4ha and the total number of Linedra erythrocarpa was 3,224. The total number of femle Linedra erythrocarpa was625(22.2%) except the seedlings under 2cm of DBH(Diameter breast of height). For the estimation of tree age by counting of tree rings, the regression equation was Y=1.79X+9.47($R^2$=0.83, DBH=cm). The soil acidity of stands studied was $pH4.6{\sim}pH5.8$. And the soil acidity of Seoul was $pH4.2{\sim}pH4.5$ So for the Planting Linedra erythrocarpa in Seoul area, the soil acidity of planting area should be changed to $pH4.6{\sim}pH5.8$. The flower size of and female of Linedra erythrocarpa was 5.96mm, 3.66mm, respectively. The length of petiole of male and female of Linedra erythrocarpa was 5.96mm, 3.66mm, respectively. The length of petiole of male and female of Linedra erythrocarpa was 5.96mm, 3.66mm, respectively. And the number of flowers per flowering bud of male and female were 13.4, 11.2, respectively. The flowering period of Lindera erythrocarpa in Suwon was 21 days from May 2 to May 22. And The leaf continuing period of Lindera erythrocarpa in Suwon was 203 days from April 7 to October 27. And the fall-foliage color continuing period was 10 days from October 18 to October 27. The fruit continuing period of Lindera erythrocarpa in Suwon was 61 days from September 26 to November 26.

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[Ni($L^2$)($H_2O$)]Cl$\cdot$$H_2O$ ($L^2$: 3,14-dimethyl-2,6,13,17-tetraazatricyclo [14,4,$0^{1.18}$,$0^{7.12}$docosane-N-acetic acid) 착물의 합성 및 결정구조 (Preparationan dCrystal Structure of [Ni($L^2$)($H_2O$)]Cl$\cdot$$H_2O$ ($L^2$: 3,14-dimethyl-2,6,13,17-tetraazatricyclo [14,4,$0^{1.18}$,$0^{7.12}$]docosane-N-acetic acid))

  • Park, Ki-Yonng;Park, Young-Soo;Kim, Jin-Gyu;Suh, Il-Hwan;Kim, Chang-Suk
    • 한국결정학회지
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    • 제10권1호
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    • pp.33-38
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    • 1999
  • The complex [Ni(L2)(H2O)]Cl·H2O (1) (L2=3,14-dimethyl-2,6,13,17-tetraazartricyclo [14,4,01.18,07.12]docosane-N-acetic acid) has been synthesized and characterized by X-ray crystallography. 1 crystallizes in the triclinic system, space group P, with a=11.274(1), b=13.851(1), c=17.159(6) , α=90.24(2), β=101.10(2), γ=92.11(1)o V=2682.5(11) 3, Z=4, R1=0.042 and wR2=0.111 for 9432 observed reflections with [I>2σ(I)]. The central nicke(II) ion is six-coordinated octahedral geometry with bonds to the four amine nitrogen atoms the carboxylic oxygen atom of the macrocyclic ligand and to the water molecule occupying a position trans to the pendant arm.

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Regulation of CYP 1A1 gene expression by retinoic acid receptor, retinoid X receptor and constitutive androstane receptor in rainbow trout hepatoma cells(RTH 149)

  • Kim, Ji-Sun;Yang, So-Yeun;Seo, Mi-Jung;Sheen, Yhun-Yhong
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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    • pp.89-89
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    • 2003
  • Exposure of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a variety of biological and toxicology effects, most of which are mediated by aryl hydrocarbon receptor (AhR). The ligand-bound AhR as a heterodimer with AhR nuclear translocator (ARNT) binds to its specific DNA recognition site, the dioxin-responsive element (DRE), and it results in increased transcription of CYP1A1 gene. Retinoic acid (RA) regulates the transcription of various genes for several essential functions through binding to two classes of nuclear receptors, the retinoic acid receptor (RAR) and retinoid X receptor (RXR). Constitutive androstane receptor (CAR) also regulates the transcription of gene. In this study, we have examined how RAR, RXR and CAR regulated CYP1A1 in rainbow trout hepatoma cell (RTH 149) using luciferase reporter gene assay system. We did transient transfection with CYP1A1 luciferase reporter gene and treated with TCDD, all-trans RA, 9-cis RA and phenobarbital. Treatment of all-trans RA, 9-cis RA or phenobarbital decreased the TCDD induced transcription of CYP1Al. When we did transient cotransfection with CYP1A1 luciferase reporter gene and RXR, as increase of RXR concentration, the TCDD induced transcription of CYP1A1 was decreased. Transfection with CAR also decreased the TCDD induced transcription of CYP1A1 in RTH 149 cells.

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Regulation of CYP 1A1 gene expression by retinoic acid receptor, retinoid X receptor and constitutive androstane receptor in rainbow trout hepatoma cells(RTH 149)

  • Kim, Ji-Sun;Yang, So-Yeun;Seo, Mi-Jung;Sheen, Yhun-Yhong
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2003년도 추계국제학술대회
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    • pp.179-179
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    • 2003
  • Exposure of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a variety of biological and toxicology effects, most of which are mediated by aryl hydrocarbon receptor (AhR). The ligand-bound AhR as a heterodimer with AhR nuclear translocator (ARNT) binds to its specific DNA recognition site, the dioxin-responsive element (DRE), and it results in increased transcription of CYP1A1 gene. Retinoic acid (RA) regulates the transcription of various genes for several essential functions through binding to two classes of nuclear receptors, the retinoic acid receptor (RAR) and retinoid X receptor (RXR). Constitutive androstane receptor (CAR) also regulates the transcription of gene. In this study, we have examined how RAR, RXR and CAR regulated CYP1A1 in rainbow trout hepatoma cell (RTH 149) using luciferase reporter gene assay system. We did transient transfection with CYP1A1 luciferase reporter gene and treated with TCDD, all-trans RA, 9-cis RA and phenobarbital. Treatment of all-trans RA, 9-cis RA or phenobarbital decreased the TCDD induced transcription of CYP1A1. When we did transient cotransfection with CYP1A1 luciferase reporter gene and RXR, as increase of RXR concentration, the TCDD induced transcription of CYP1A1 was decreased. Transfection with CAR also decreased the TCDD induced transcription of CYP1A1 in RTH 149 cells.

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Crystal Structure of Thiamin Tetrahydrofurfuryl Disulfide

  • Shin, Whan-Chul;Kim, Young-Chang
    • Bulletin of the Korean Chemical Society
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    • 제7권5호
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    • pp.331-334
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    • 1986
  • The crystal structure of thiamin tetrahydrofurfuryl disulfide, one of the ring-opened derivatives of thiamin, has been determined by the X-ray diffraction methods. The crystal is monoclinic with cell dimensions of a = 8.704 (1), b = 11.207 (2), c = 21.260 (3) ${\AA}$ and ${\beta}$ = 92.44 (2)$^{circ}$, space group P2$_{1}$/c and Z = 4. The structure was solved by direct methods and refined to R = 0.076 for 1252 observed reflections measured on a diffractometer. The molecule assumes a folded conformation in which the pyrimidine and the tetrahydrofurfuryl rings are on the same side of the ethylenic plane. The pyrimidinyl, N-formyl and ethylenic planes are mutually perpendicular to each other and the N(3)-C(4) bond retains a single bond character. The structure is stabilized by an intramolecular N(4'${\alpha})-H{\cdots}O(2{\alpha}$) hydrogen bond. The molecules are connected via N(4'${\alpha}$)-H{\cdots}(N3')$ and O(5${\gamma})-H{\cdots}(N1')$ hydrogen bonds, forming a two-dimensional hydrogen-bonding network. The tetrahydrofurfuryl ring is dynamically disordered. The overall conformation as well as the packing mode is very similar to that of thiamin propyl disulfide.

벤지딘으로 오염된 음용수를 섭취한 흰쥐에서 간장세포와 방광세포에 형성된 발암물질- DNA adduct에 관한 연구 (Carcinogen-DNA adducts in Liver and Bladder of Sprague-Dawley rats treated with benzidine in drinking water)

  • 이진헌;신호상;장미선;홍춘표;최석남
    • 한국환경보건학회지
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    • 제27권3호
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    • pp.63-70
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    • 2001
  • To identify and evaluate the benzidine-DNA adducts in liver and bladder, we exposed the 80 ppm benzidine to 40 sprague-dawley rats by drinking water for 4 weeks(6.2 mg/kg body wt./day). Only one benzidine-DNA adduct was found at the same site of thin layer chromatogram of $^{32}$ P-postlabeling method in the liver and bladder of exposed rats. So we know the DNA adduct formed at liver and bladder were similar to each other, which was N-(deoxyguanosin-8-yl)-N'-acetylbenzidine. Relative adduct labeling(RAL) of DNA adduct was similar to each other for 1 and 2 weeks, but that in liver was significantly higher than in bladder for 3 and 4 weeks. RAL$\times$10$^{9}$ of DNA adduct were 84.45$\pm$11.31 and 152.8$\pm$5.53 in liver, and were 24.76$\pm$7.06 and 38.00$\pm$10.57 in bladder for 3 and 4 weeks, respectively. Regression equation between liver and bladder was Y=-3.801+2.507 X(r=0.6036, p<0.01). In conclusion, benzidine-DNA adduct formed in liver was significantly higher than that in bladder, with the similar compound structure in sparague-dewley rates treated benzidine in drinking water.

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조상설비를 고려한 전압안정성 여유전력의 평가에 관한 연구 (A Study for Evaluating of Voltage Stability Margin Considering Shunt Capacitor)

  • 김세영
    • 에너지공학
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    • 제7권1호
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    • pp.65-72
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    • 1998
  • 이 논문은 극좌표이 선로조류방정식을 이용하여 전압안정성 여유전력을 평가하는 고속계산법을 제안한다. 여기서, 선로조류방정식은 상태변수 Vi, $\delta$i, Vj와 $\delta$i 그리고, 선로정수 r과 x로 구성되는데 극좌표계의 특징을 이용하면 이것은 두 개의 변수 Vi와 Vj를 가진 하나의 식이 된다. 그리고, j 모선이 조류계산에서 전압크기로 지정되는 발전기 또는 slack 모선이라면, 변수 Vi만을 가진 하나의 식 즉, {{{{ { V}`_{i } ^{2 } }}에 대한 2차 방정식으로 정식화된다. 그러므로, 전력조류다근은 간단한 계산을 통해 구할 수가 있는데 이와 같이 구해진 다근은 감도해석 또는 다근의 근접도를 통해 전압안정도를 평가할 수 가 있었다. 또한, 전압안정도 평가시에 중요한 요소인 전력용 콘덴서와 같은 조상설비를 고려하여 전압안정성 여유전력을 평가하는 방법을 개발하였다. 제안한 방법을 시험계통에 적용하여 유효성을 입증하였다.

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RF magnetron sputtering법에 의해 제조된 $\textrm{SrBi}_{2}\textrm{Ta}_{2}\textrm{O}_{9}$박막의 강유전 특성에 관한 연구 (Ferroelectric Properties $\textrm{SrBi}_{2}\textrm{Ta}_{2}\textrm{O}_{9}$ Thin Films Deposited by RF Magnetron Sputtering Technique)

  • 박상식;양철훈;윤순길
    • 한국재료학회지
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    • 제7권6호
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    • pp.505-509
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    • 1997
  • FRAM(Ferroelectric Random Access memory)에의 응용을 위해 rf magnetron sputtering법을 이용하여 SrB $i_{2}$T $a_{2}$ $O_{9}$(SBT)박막을 증착하였다. 사용된 기판은 Pt/Ti/Si $o_{2}$Si이었으며 50$0^{\circ}C$에서 증착한 후 80$0^{\circ}C$의 산소 분위기 하에서 1시간 동안 열처리하였다. 증착시 증착 압력을 변화시켜 가면서 이에 따른 특성의 변화를 고찰하였다. 박막내의 Bi와 Sr의 부족을 보상하기 위해 20mole%의 Bi $O_{2}$와 30mole%의 SrC $O_{3}$를 과잉으로 넣어 타겟을 제조후 사용하였고 박막들의 두께는 300nm의 두께를 가지며 증착압력에 따라 다른 미세 구조르 보였다. 10mtorr에서 증착한 박막의 조성은 S $r_{0.6}$B $i_{3.8}$Ta/ sub 2.0/ $O_{9.0}$이었다. 이 SBT 박막의 잔류 분극(2 $P_{r}$)과 보전계(2 $E_{c}$)값은 각각 인가 전압 5V에서 18.5 $\mu%C/$\textrm{cm}^2$과 150kV/cm이었고, signal/noise비는 3V에서 4.6을 나타내었다. 5V의 bipolar pulse하에서 $10^{10}$cycle까지 피로 현상이 나타나지 않았으며, 누설 전류 밀도는 133kV/cm에서 약 1x$10^{-7A}$$\textrm{cm}^2$의 값을 보였다.을 보였다.

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Maximum number of total born piglets in a parity and individual ranges in litter size expressed as specific characteristics of sows

  • Freyer, Gertraude
    • Journal of Animal Science and Technology
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    • 제60권5호
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    • pp.13.1-13.7
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    • 2018
  • Background: The objective of this study was to underline that litter size as a key trait of sows needs new parameters to be evaluated and to target an individual optimum. Large individual variation in litter size affects both production and piglet's survival and health negatively. Therefore, two new traits were suggested and analyzed. Two data sets on 5509 purebred German Landrace sows and 3926 Large White and crossing sows including at least two parental generations and at least five parities were subjected to variance components analysis. Results: The new traits for evaluating litter size were derived from the individual numbers of total born piglets (TBP) per parity: In most cases, sows reach their maximum litter size in their fourth parity. Therefore, data from at least five parities were included. The first observable maximum and minimum of TBP, and the individual variation expressed by the range were targeted. Maximum of TBP being an observable trait in pig breeding and management yielded clearly higher heritability estimates ($h^2{\sim}0.3$) than those estimates predominantly reported so far. Maximum TBP gets closer to the genetic capacity for litter size than other litter traits. Minimum of TBP is positively correlated with the range of TBP ($r_p=0.48$, $r_g$ > 0.6). The correlation between maximum of TBP and its individually reached frequency was negative in both data sets ($r_p=-0.28$ and - 0.22, respectively). Estimated heritability coefficients for the range of TBP comprised a span of $h^2=0.06$ to 0.10. Conclusion: An optimum both for maximum and range of total born piglets in selecting sows is a way contributing to homogenous litters in order to improving the animal-related conditions both for piglets' welfare and economic management in pig.

양궁 올림픽 라운드기록에 영향을 미치는 팔로 드로우 국면의 운동학적 요인 평가 (Evaluation on Kinematic Factors Affecting Scores of Olympic Round Game during the Follow Through in Archery)

  • 하종규;이재훈
    • 한국운동역학회지
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    • 제18권1호
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    • pp.227-234
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    • 2008
  • 이 연구의 목적은 올림픽 라운드기록에 영향을 미치는 운동학적인 요인을 구명하는 것이다. 대상자는 K 대학교의 숙련된 양궁선수 8명(나이: $20{\pm}1$세 무게: $77{\pm}13kg$, 신장: $178{\pm}5cm$)이 참여하였으며, 올림픽 라운드 상황과 동일 조건에 준하여 개인별 12회 총 72회의 슈팅을 7대의 고속 적외선 디지털 카메라(MCU-240)로 촬영하였다. 그 결과 첫째, 기록별 견관절의 평균 각속도가 기록에 미치는 영향은 통계적으로 유의한(p=.65<.10) 것으로 나타났으며 회귀식은 y=-0.0637x +17.074이고 결정계수는 $R^2$=0.874이었다. 둘째, 견관절의 평균 각속도가 약 $120^{\circ}$/sec.에서 고득점이 분포하였다. 셋째, 견관절의 평균 각속도가 느려질수록 기록이 크게 나타났다. 결론적으로 회귀식은 정의역, $110^{\circ}$/sec.< x <$160^{\circ}$/sec.에서 견관절 평균 각속도가 낮을수록 기록이 증가하였고 약 87%의 설명력을 가졌다.