• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2011년도 춘계학술논문집 1부
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• pp.428-432
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• 2011

차량 통신 네트워크(VANET, Vehicle Ad hoc NETwork)는 ITS(Intelligent Transport System)의 발전과 함께 운전자의 안전 및 교통 정보, 긴급 메시지 등과 같은 서비스를 실시간으로 가능하게 할 수 있는 차세대 네트워크 기술이다. 이러한 차량 통신 네트워크는 현재 IEEE P1609에서 정의하고 있으며, WAVE(Wireless Access Vehicular Environment)로 알려져 있다. WAVE는 차량에 설치된 OBU(Onboard Unit)와 주변시설에 설치된 RSU(Road Side Unit)을 통하여 통신하며, 차량 간 통신을 지원하는 V2V(Vehicle to Vehicle)와 차량과 주변시설과의 통신을 지원하는 V2I(Vehicle to Infrastructure)로 나뉘어져 있다. 하지만 WAVE에서 정의하고 있는 네트워크 서비스(IEEE P1609.4)는 OBU와 RSU 간의 네트워크 서비스에 초점을 맞추고 있기 때문에 전체 네트워크의 QoS를 보장하기에는 미흡한 상태이다. 따라서 본 논문에서는 차량 통신 네트워크에서 End-to-End 간의 QoS 보장을 위한 무선 메쉬 네트워크 기반의 라우팅 알고리즘을 제안한다. 제안하는 알고리즘은 무선 메쉬 네트워크 노드의 호스트 라우터 기능을 통하여 차량 노드와 이기종 간의 네트워크 서비스를 가능하게 하며, 무선 메쉬 네트워크의 다중 채널을 이용하여 데이터의 중요도에 따른 차등 서비스를 지원한다. ns-2를 이용한 시뮬레이션 결과 제안하는 알고리즘이 QoS를 보장함으로써 차량 통신 네트워크의 성능을 향상시킬 수 있음을 입증하였다.

• 한국정보통신학회논문지
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• 제23권12호
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• pp.1609-1617
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• 2019

ECC (Elliptic Curve Cryptography)와 RSA를 기반으로 하는 다양한 공개키 암호 프로토콜 구현을 지원하는 하드웨어 가속기 설계에 관해 기술한다. NIST 표준으로 정의된 소수체 상의 5가지 타원곡선과 3가지 키길이의 RSA를 지원하며 또한, 4가지 타원곡선 점 연산과 6가지 모듈러 연산을 지원하도록 설계되어 ECC와 RSA 기반 다양한 공개키 암호 프로토콜의 하드웨어 구현에 응용될 수 있다. 저면적 구현을 위해 내부 유한체 연산회로는 32 비트의 데이터 패스로 설계되었으며, 워드 기반 몽고메리 곱셈 알고리듬, 타원곡선 점 연산을 위해서는 자코비안 좌표계, 그리고 모듈러 곱의 역원 연산을 위해서는 페르마 소정리를 적용하였다. 설계된 하드웨어 가속기를 FPGA 디바이스에 구현하여 EC-DH 키교환 프로토콜과 RSA 암호·복호 둥작을 구현하여 하드웨어 동작을 검증하였다. 180-nm CMOS 표준 셀 라이브러리로 합성한 결과, 50 MHz 클록 주파수에서 20,800 등가게이트와 28 kbit의 RAM으로 구현되었으며, Virtex-5 FPGA 디바이스에서 1,503 슬라이스와 2개의 BRAM으로 구현되었다.

• 한국식품영양과학회지
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• 제37권12호
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• pp.1609-1614
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• 2008

국내 주요 생산지인 전남 무안, 전북 부안, 경북 안동 및 경남 창녕의 3개 지역(유어, 장마, 성산)에서 수거된 양파 6종의 휘발성향기성분을 SPME법으로 추출하여 GC/MSD 로 분석하였다. 총 51종의 화합물이 동정되었는데, 이는 함황화합물류(20종), 알데히드류(4종), 케톤류(5종), 에스테르류(11종), 방향족화합물류(4종), 함질소화합물류(2종) 및 기타화합물류(5종)로 구성되었다. 함황화합물류가 총 휘발성 향기성분 함량의 $62.6{\sim}80.3%$를 차지하였으며, 함량 면에서는 안동(4,828 ng/g), 부안(4,627 ng/g), 유어(4,149 ng/g), 장마(2,979 ng/g), 성산(2,758 ng/g) 및 무안(2,171 ng/g) 순으로 많았다(p<0.05). 항산화효과가 있는 5종의 함황화합물류 (2,4-, 2,5-dimetylthiophene, 2-vinyl-1,3-dithiane, 5-methoxy thiazole, 3,5-diethyl-1,2,4-trithiolane)는 안동, 유어, 장마, 부안, 성산 및 무안 순이었고, 항암효과가 있는 함황화합물류 5종((Z)-, (E)-methyl propenyl disulfide, (Z)-, (E)- propenyl propyl disulfide, di-2-propenyl disulfide)은 부안, 유어, 안동, 장마, 성산 및 무안 순으로 많았다.

• Journal of the Korean Data and Information Science Society
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• 제27권6호
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• pp.1609-1619
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• 2016

본 연구는 한국형 웰니스 생활양식 측정도구의 구성타당도와 신뢰도를 확인하기 위한 도구개발 연구이다. 간호대학생 345명이 99문항의 WEL (wellness evaluation of lifestyle)을 작성하였고, SPSS WIN 22.0와 AMOS 18.0을 이용한 탐색적 요인분석과 확인적 요인분석을 통해 측정도구의 구성타당도를 검증하였다. 최종 한국형 웰니스 생활양식 측정도구는 71문항, 14개 하위척도로 구성되었다. 각 하위척도는 4개의 요인구조를 가지는 것으로 확인되었다: 본질적 자기, 사회적 자기, 신체적 자기, 적응적 자기, 모델의 적합도는 ${\chi}^2=225.12$, p<.001, CMIN/DF=3.17, RMSEA=.08, NFI=.87, IFI=.91, CFI=.91로 나타났다. 도구의 집중타당도를 평가한 결과 기각비 (C.R.)는 2.95~16.84로였고, 표준분산추출 (AVE)도 .61~.69로 수용 가능하였다. 하위척도의 내적 일치도 Cronbach's ${\alpha}$는 .55~.87이었다. 본 연구를 통해 한국형 웰니스 생활양식 측정도구가 한국인의 웰니스를 다차원적으로 측정하기에 타당하고 신뢰성있는 도구임을 확인하였다.

• 한국농공학회논문집
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• 제58권2호
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• pp.83-90
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• 2016

This study was performed to evaluate the effective analysis of flexural performance for polypropylene fiber (PF) reinforced EVA concrete that can be used in marine bridge, tunnel and agricultural structures under flexural load. The control design was applied in ready mixed concrete using 10 % fly ash of total binder weight used in batch plant. On the basis of the control mix design, there was designed mix types that contained PF ranged from 0 % to 0.5 % by volume ratio into two mix types of using 0 % and 5.0 % EVA contents of total binder weight. Before evaluating the flexural performance, we tested compressive strength and flexural strength to evaluate whether polypropylene fiber reinforced concrete could be used or not in site. The method of flexural performance evaluation was applied by ASTM C 1609. These results showed the maximum compressive strength and flexural strength was measured at each E5P1 and E5P2. Concrete reinforced with PF exhibited deflection-softening behavior. In the concrete reinforced with 0.4 % PF contents and containing 5.0 % EVA, the flexural performance was the best.

• Journal of Microbiology and Biotechnology
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• 제27권4호
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• pp.775-784
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• 2017

A neutral xylanase (CcXyn) was identified from Coprinus cinereus. It has a single GH10 catalytic domain with a basic amino acid-rich extension (PVRRK) at the C-terminus. In this study, the wild-type (CcXyn) and C-terminus-truncated xylanase ($CcXyn-{\Delta}5C$) were heterologously expressed in Pichia pastoris and their characteristics were comparatively analyzed with aims to examine the effect of this extension on the enzyme function. The circular dichorism analysis indicated that both enzymes in general had a similar structure, but $CcXyn-{\Delta}5C$ contained less ${\alpha}-helices$ (42.9%) and more random coil contents (35.5%) than CcXyn (47.0% and 32.8%, respectively). Both enzymes had the same pH (7.0) and temperature ($45^{\circ}C$) optima, and similar substrate specificity on different xylans. They all hydrolyzed beechwood xylan primarily to xylobiose and xylotriose. The amounts of xylobiose and xylotriose accounted for 91.5% and 92.2% (w/w) of total xylooligosaccharides (XOS) generated from beechwood by CcXyn and $CcXyn-{\Delta}5C$, respectively. However, truncation of the C-terminal 5-amino-acids extension significantly improved the thermostability, SDS resistance, and pH stability at pH 6.0-9.0. Furthermore, $CcXyn-{\Delta}5C$ exhibited a much lower $K_m$ value than CcXyn (0.27 mg/ml vs 0.83 mg/ml), and therefore, the catalytic efficiency of $CcXyn-{\Delta}5C$ was 2.4-times higher than that of CcXyn. These properties make $CcXyn-{\Delta}5C$ a good model for the structure-function study of $({\alpha}/{\beta})_8$-barrel-folded enzymes and a promising candidate for various applications, especially in the detergent industry and XOS production.

• Journal of Microbiology and Biotechnology
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• 제27권4호
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• pp.747-758
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• 2017

Chronic wounds, pressure sores, lesions, and infections of microbial origin in bedridden, paralyzed, or malnutrition patients remain the object of study of many researchers. A variety of factors behind the development of these disorders are related to the patient's immune system, making it unable to respond effectively to the treatment of the wound. These factors can be properly controlled, giving particular importance to the ethiology and stage of the wound, as well as the time periods corresponding to the replacement of the dressings. The present research reports a novel foam/soft material, ${{\small}L}$-Cys-g-PCL, with an application for decubitus/pressure ulcers, especially for wounds with a difficult healing process due to infections and constant oxidation of the soft tissues. During this work, the interactions between S. aureus and ${{\small}L}$-Cys-g-PCL foam were studied under conditions that simulate decubitus ulcers; namely, pH and exudate. The effects of duration of grafting (1 or 8 h) and pH (7.0 and 8.9) on wettability, surface energy, swelling, and porosity were also evaluated. Results showed an effective microbicidal activity exhibiting an inhibition ratio of 99.73% against S. aureus. This new ${{\small}L}$-Cys-g-PCL soft material showed saftey to contact skin, ability to be shaped to fill in sunken holes (craters) - pressure ulcers stage III - and to act as a smart material responsive to pH, which can be tailored to develop better swelling properties at alkaline pH where exudates are normally higher, so as to address exudate self-cleaning and prevention of desiccation.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1603-1609
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• 2014

Background: The response to treatment and overall survival (OS) of patients with acute myeloid leukemia (AML) is variable, with a median ranging from 6 months to 11.5 years. TP53 is associated with old age, chemotherapy resistance, and worse OS. Using genetic sequencing, we set out to look at our own experience with AML, and hypothesized that both TP53 mutations and SNPs at codon 72 would mimic the literature by occurring in a minority of patients, and conferring a worse OS. Materials and Methods: We performed a pilot study of randomly selected, newly diagnosed AML patients at Mount Sinai Medical Center, diagnosed from 2005-2008 (n=10). TP53 PCR sequencing was performed using DNA from bone marrow smears. Analysis was accomplished using Mutation Surveyor software with confirmation of the variants using the COSMIC and dbSNP databases. Results: Fewer than half of the patients harbored TP53 mutations (40%). There was no significant difference in OS based on gender, AML history, risk-stratified karyotype, or TP53 mutation. There were possible trends toward improved survival among patients less than 60 (11 vs 4 months, p=0.09), Hispanics (8 vs 1 months, p=0.11), and those not harboring SNP P72R (8 vs 2 months, p=0.10). There was a significant improvement in survival among patients with better performance status (28 vs 4 months, p=0.01) and those who did not have a complex karyotype (8 vs 1 months, p=0.03). The most commonly observed TP53 mutation was a missense N310K (40%) and the most commonly observed SNP was P72R (100.0%). Conclusions: Our study confirms previous reports that poor PS and the presence of a complex karyotype are associated with a decreased OS. In our cohort, TP53 mutations were relatively common, occurring more frequently in male patients with an adverse karyotype. Although there was no significant difference in survival between TP53 mutated and un-mutated patients, there was a possible trend toward worse OS among patients with SNP P72R. Larger studies are needed to validate these findings.

• Journal of Microbiology and Biotechnology
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• 제27권2호
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• pp.271-276
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• 2017

A highly thermostable ${\beta}-(1-4)-glucanase$ (NA23_08975) gene (fig) from Fervidobacterium islandicum AW-1, a native-feather degrading thermophilic eubacterium, was cloned and expressed in Escherichia coli. The recombinant FiG (rFiG) protein showed strong activity toward ${\beta}-{\small{D}}-glucan$ from barley (367.0 IU/mg), galactomannan (174.0 IU/mg), and 4-nitrophenyl-cellobioside (66.1 IU/mg), but relatively weak activity was observed with hydroxyethyl cellulose (5.3 IU/mg), carboxymethyl cellulose (2.4 IU/mg), and xylan from oat spelt (1.4 IU/mg). rFiG exhibited optimal activity at $90^{\circ}C$ and pH 5.0. In addition, this enzyme was extremely thermostable, showing a half-life of 113 h at $85^{\circ}C$. These results indicate that rFiG could be used for hydrolysis of cellulosic and hemicellulosic biomass substrates for biofuel production.

• 한국약용작물학회지
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• 제23권4호
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• pp.277-283
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• 2015

This study was conducted to investigate the selected chemical properties of soils in Saururus chinensis Baill (Chinese lizard's tail) cultivation fields to provide optimal fertilizer application rates and to examine the growth and pharmaco-consitituents of Saururus chinensis Baill as influenced by different amounts of nitrogen (N) fertilizer applications. Based on the results of selected soil chemical properties in 37 cultivation sites of the plant, soil pH, organic matter content, and exchangeable $K^{+}$ concentration were lower than optimal values for cultivating general medicinal crops even though relatively high standard deviations were found in some of the values. At the harvesting stage of the plant aerial parts, soil pH, electrical conductivity (EC), available $P_2O_5$, and exchangeable $Ca^{2+}$, $Mg^{2+}$, $Na^{+}$ decreased as comparing with those before transplanting the plant, whereas the concentration of exchangeable $K^{+}$ increased in the plot treated with N 100% and compost. Fresh weight of the plant aerial parts were highest, 492.5kg/10, in the N 100% treatment plot. Correlation equation between N levels treated (X) and yield of the plant aerial parts (Y) presented as $Y=-2.1609X^2+30.082X+344.12$($R^2= 0.7113$) and the optimal rate of N fertilizer application for the plant was 6.6kg/10a. Carbon concentrations in the plant were not different among the different N levels applied. N and K concentrations in the plant were highest in the plot of N 100% with compost applications, the highest P concentration was in N 100% plot, and the highest Ca and S concentrations were in N 200% plot. Quercetin and quercitrin were highest in the N 150% plot and tannin was highest in N 100% or N 100% with compost application plot.