• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 추계학술대회 논문집 전기물성,응용부문
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• pp.112-115
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• 2002

The effects of processing aids(P.A.) in semicoductive compounds(S.C.) with highly loaded carbon black for extra high voltage cables were investigated. The processability of S.C. is improved as the contents of P.A. increased, however, the electrical, mechanical properties and smoothness of S.C. grew worse, especially for the S.C. which contains 5wt% of P.A., the volume resistivity after heat cycle which shows long term reliability increased about three times after 15cycles compared to the S.C. which contains no P.A. We inferred that it is caused by the action of P.A. as the insulating sites, thermal expansion of polymer matrix which leads the length between carbon blacks to shorten, and the decrease of degree of crosslinking. The change of ion contents which means cleanliness of S.C. is not occured regardless of the addition of P.A.

• The Korean Journal of Physiology and Pharmacology
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• 제26권3호
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• pp.183-193
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• 2022

MicroRNAs (miRNAs) regulate gene expression and are biomarkers for coronary atherosclerosis (AS). A novel miRNA-mRNA regulation network of coronary AS still needs to be disclosed. The aim of this study was to analyze potential mRNAs in coronary AS patients and the role of their upstream miR-491-5p in vascular smooth muscle cells (VSMCs). We first confirmed top ten mRNAs according to the analysis from Gene Expression Omnibus database (GSE132651) and examined the expression levels of them in the plaques and serum from AS patients. Five mRNAs (UBE2G2, SLC16A3, POLR2C, PNO1, and AMDHD2) presented significantly abnormal expression in both plaques and serum from AS patients, compared with that in the control groups. Subsequently, they were predicted to be targeted by 11 miRNAs by bioinformatics analysis. Among all the potential upstream miRNAs, only miR-491-5p was abnormally expressed in the plaques and serum from AS patients. Notably, miR-491-5p overexpression inhibited viability and migration, and significantly increased the expression of contractile markers (α-SMA, calponin, SM22α, and smoothelin) in VSMCs. While silencing miR-491-5p promoted viability and migration, and significantly suppressed the expression of α-SMA, calponin, SM22α, and smoothelin. Overall, miR-491-5p targeted UBE2G2, SLC16A3, and PNO1 and regulated the dysfunctions in VSMCs.

• Archives of Plastic Surgery
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• 제36권4호
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• pp.372-379
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• 2009

Purpose: The purpose of this study was to compare the effect on antibacterial activities and wound healing effect of silver containing dressings with which of Betadine against Staphylococcus aureus and Pseudomonas aeruginosa. Methods: One full thickness skin defects in rats(n=72) were developed on the back and were given rise to infection with S. aureus(n=36) and P. aeruginosa(n=36). The 72 mice were divided into 6 groups : Acticoat$^{(R)}$, Aquacel$^{(R)}$-Ag, Medifoam silver$^{(R)}$, Polymen silver$^{(R)}$, Ilvadon$^{(R)}$ and Betadine(control group) dressing groups. Five silver containing dressings and Betadine were assesed on infected wound. Measurement of wound size change, bacterial colonies count and histologic findings was applied. Antibacterial activity was analyzed with bacterial restricted zone in Mueller Hinton agar. Results: On S. aureus, wound size was more decreased in all treated groups as compared with betadine, however Ilvadon$^{(R)}$ was less decreased on P. aeruginosa. In histologic findings, experimental group showed more effective findings than others on S. aureus, however on P. aeruginosa, which was showed similar. Acticoat$^{(R)}$ was best effective in wound healing against S. aureus and P. aeruginosa. The bacterial colonies count was increased in all treated groups except Acticoat$^{(R)}$ as compared with the control group on S. aureus, which was decreased in Acticoat$^{(R)}$ and Ilvadon$^{(R)}$ group on P. aeruginosa. There were not statistical differences. The restricted zone was shown in Mueller - Hinton agar of all groups except Medifoam silver$^{(R)}$ group on S. aureus, which was shown of all groups on P. aeruginosa. There were statistical differences. Conclusion: This study suggests that silver containing dressings may have not better potential than Betadine in assisting management of wounds at risk of infection on S. aureus and P. aeruginosa. However, which have better antibacterial activity on S. aureus and P. aeruginosa.

• 한국산학기술학회논문지
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• 제18권11호
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• pp.459-468
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• 2017

본 연구는간호대학생의 비만스트레스와 건강신념이 체중조절행위에 미치는 영향을 파악하기 위해 시도되었다. 자료 수집은 2016년 9월 1일부터 10월 10일까지 U시에 소재한 대학교에 재학 중인 간호대학생을 대상으로 설문조사를 실시하였으며, 수집된 자료는 SPSS 23.0프로그램을 이용하여 t-test, ANOVA, Scheffe test, Person's correlation coefficients와 위계적 다중회귀분석(Hierarchical multiple regression analysis)으로 분석하였다. 대상자의 일반적 특성 중 성별(t=2.30, p=.044), 건강상태(F=8.03, p<.001)가 체중조절행위에 유의하게 영향을 주었다. 체중조절행위의 식이요법(r=-.26, p<.001), 운동요법(r=-.25, p<.001)과 행동수정요법(r=-.29, p<.001)이 지각된 장애성과 유의한 음의 상관관계가 있으며, 체중조절행위의 전문지식획득은 비만스트레스(r=.42, p<.001), 지각된 민감성(r=.25, p<.001)과 지각된 유익성(r=.19, p<.001)이 유의한 양의 상관관계가 있는 것으로 나타났다. 또한, 간호대학생의 체중조절행위에 유의한 영향을 준 것은 건강신념 중 지각된 장애(${\beta}=-.30$, p<.001)와 비만스트레스(${\beta}=.20$, p<.05) 순으로 나타났고, 이들 변인들의 총 설명력은 17.2%이었다. 이상의 결과를 토대로 간호대학생의 체중조절행위에 영향을 주는 성별, 건강상태 및 비만스트레스와 건강신념의 변인들을 이용하여 체중조절행위를 실천할 수 있는 효율적인 교육 및 프로그램의 개발과 적용이 요구된다.

• 한국산학기술학회논문지
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• 제21권1호
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• pp.103-111
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• 2020

본 연구는 간호대학생의 결혼관, 자녀관, 출산양육동기, 출산의지의 정도를 알아보고, 출산의지에 영향을 미치는 요인을 확인하여 출산의지를 높이기 위한 기초자료를 제공하기 위하여 시도된 서술적 조사연구이다. 연구대상자는 B시의 2개 대학교 간호대학생을 대상으로 자료수집은 2019년 5월 1일부터 30일까지 였고, 최종 248부를 분석에 사용하였다. 수집된 자료는 SPSS 22.0 프로그램을 이용하여 실수, 백분율, 평균, 표준편차, 독립 t-검증, 일원분산분석, 피어슨 상관계수, 다중회귀분석으로 분석하였다. 연구결과 연구대상자의 결혼관, 자녀관, 출산양육동기, 출산의지의 정도는 결혼관 평균 3.39±.38점, 자녀관 평균 2.72±0.39점, 출산양육동기 평균 2.73±0.78점, 출산의지 평균 3.12±0.48점으로 나타났다. 일반적 특성에 따른 출산의지의 차이에서 연령(F=6.002, p=.003)에서 유의한 차이를 나타냈다. 연구대상자의 결혼관, 자녀관, 출산양육동기와 출산의지와의 상관관계에서 출산의지는 결혼관 중 보수적 결혼관(r=.207, p=.001), 적극적 결혼관(r=.226, p<.001), 도구적 결혼관(r=.181, p=.004), 양육동기(r=.283, p<.001)와 정적 상관관계를 나타냈다. 출산의지는 결혼관 중 소극적 결혼관(r=-.292, p<.001), 자녀관(r=-.226, p<.001)과는 부적상관관계를 나타냈다. 연구대상자의 출산의지에 영향을 미치는 요인은 연령(β=.212, p<.001), 결혼관(β=-.318, p<.001), 출산양육동기(β=.227, p=.006)로 나타났고, 설명력은 20.2%였다. 본 연구를 통하여 간호대학생의 출산의지에 영향을 미치는 다양한 요인을 확인하기 위한 반복연구가 필요하다.

• 보건교육건강증진학회지
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• 제17권2호
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• pp.125-149
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• 2000

The purpose of this study was practiced to investigate factors affecting dental hygienists's stress. The results executed by percentage and Likert scale (on a scale of 5) producing a mean standard deviation, T-test, one way ANOV A and person correlation coefficient using SPSS according to purpose of study. The results of study were as follows: 1. Mean point of stress from administration system dental hygienists's was 3.49 2. The dental hygienists's job place was significantly related to stress from duty volume (p=0.000), stress from personal relation(p=0.028) and stress from atmosphere of job(p=0.000). 3. The dental hygienists's career was significantly related to stress from safe job. 4. The dental hygienists's grade in rank was significantly related to stress from pride ＆ self-conceit. 5. The number of colleague worked public health center was significantly related to stress from duty volume. 6. There is a significant relationship between stress from duty volume and stress from conflict of job(p〈0.01, r=0.280). There is a significant relationship between stress from dissatisfaction and stress from personal relationship(p〈0.001, r=0.396). There is a significant relationship between stress from pride ＆ self-conceit and stress from personal relationship(p〈0.001, r=0.423). There is a significant relationship between stress from personal relationship and stress from atmosphere of job(p〈0.001, r=0.662).

• Animal Systematics, Evolution and Diversity
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• 제36권1호
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• pp.10-14
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• 2020

Pagurus is the most diverse hermit crab genus in Korea. In this study, the cytochrome c oxidase subunit I (COI) and 16S rRNA of 24 individuals from four Korean Pagurus species (i.e., 7 Pagurus brachiomastus, 8 P. proximus, 8 P. simulans, and 1 P. rectidactylus) were sequenced and analyzed. No genetic difference was found between the COI and 16S rRNA sequences of P. brachiomastus and P. simulans, and the COI sequences of P. rectidactylus and P. quinquelineatus (comparative species from NCBI). Considering the morphological and ecological characteristics together, we assume that P. simulans and P. rectidactylus are subspecies of P. brachiomastus and P. quinquelineatus, respectively. This study should facilitate further research on the taxonomic status of these species.

• Molecules and Cells
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• 제45권3호
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• pp.122-133
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• 2022

The aim of this study was to investigating whether lncRNA H19 promotes myocardial fibrosis by suppressing the miR-29a-3p/miR-29b-3p-VEGFA/TGF-β axis. Patients with atrial fibrillation (AF) and healthy volunteers were included in the study, and their biochemical parameters were collected. In addition, pcDNA3.1-H19, si-H19, and miR-29a/b-3p mimic/inhibitor were transfected into cardiac fibroblasts (CFs), and proliferation of CFs was detected by MTT assay. Expression of H19 and miR-29a/b-3p were detected using real-time quantitative polymerase chain reaction, and expression of α-smooth muscle actin (α-SMA), collagen I, collagen II, matrix metalloproteinase-2 (MMP-2), and elastin were measured by western blot analysis. The dual luciferase reporter gene assay was carried out to detect the sponging relationship between H19 and miR-29a/b-3p in CFs. Compared with healthy volunteers, the level of plasma H19 was significantly elevated in patients with AF, while miR-29a-3p and miR-29b-3p were markedly depressed (P < 0.05). Serum expression of lncRNA H19 was negatively correlated with the expression of miR-29a-3p and miR-29b-3p among patients with AF (r_s = -0.337, r_s = -0.236). Moreover, up-regulation of H19 expression and down-regulation of miR-29a/b-3p expression facilitated proliferation and synthesis of extracellular matrix (ECM)-related proteins. SB431542 and si-VEGFA are able to reverse the promotion of miR-29a/b-3p on proliferation of CFs and ECM-related protein synthesis. The findings of the present study suggest that H19 promoted CF proliferation and collagen synthesis by suppressing the miR-29a-3p/miR-29b-3p-VEGFA/TGF-β axis, and provide support for a potential new direction for the treatment of AF.

• 종양간호연구
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• 제11권3호
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• pp.237-246
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• 2011

Purpose: The aim of this study was to investigate the relationships between stigma, distress, and quality of life (QOL) in patients with lung cancer. Methods: The subjects of the study were 123 lung cancer patients who visited the outpatient department of S hospital in Seoul from July 21st to August 29th, 2011. To measure stigma, distress, and QOL, Cataldo Lung Cancer Stigma Scale, Hospital Anxiety and Depression Scale (HADS), and EORTC QLQ-C30 (Quality of Life Questionnaire, Core 30) were used in this study. The collected data were analyzed using frequency, average, t-test, ANOVA, and Pearson correlation with SPSS WIN 19.0. Results: Stigma showed positive correlations with anxiety, depression, and symptom (r=.37, p<.001; r=.44, p<.001; r=.23 p=.012), while it showed negative correlations with global QOL and function (r=-.26, p=.003; r=-.40, p<.001). Anxiety and depression also positively correlated with symptoms (r=.43, p<.001; r=.58, p<.001) while anxiety and depression negatively correlated with global QOL (r=-.40, p<.001; r=-.56, p<.001) and function (r=-.64, p<.001; r=-.66, p<.001). Conclusion: The findings of the study demonstrated that lung cancer patients experienced stigma and distress that had a negative influence on the subjects' QOL. Thus the study's findings can be useful in developing psychosocial nursing strategies to improve QOL of lung cancer patients in the future.

• Physical Therapy Rehabilitation Science
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• 제9권4호
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• pp.261-268
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• 2020

Objective: This study was conducted to provide basic data on physical function improvement activities of elderly care facilities by identifying the degree of physical improvement activities of elderly caregivers. Design: Descriptive correlational study. Methods: The instrument of this study consisted of 12 questions on the general characteristics of the subject. For the assessment of improvement in physical function activities, the measuring tool used for the elderly consisted of a total of 20 questions. For data analysis, Pearson's correlation coefficient & Spearman's rho and multiple regression were used. Results: The higher the age of the subjects, the lower their educational background (r=-0.273, p<0.05), and the higher the probability of having a religion (r=-0.258, p<0.05), the more stable the employment type (r=-0.333, p<0.05). The higher the level of education, the higher the monthly income (r=0.187, p<0.01), and the shorter the career (r=-0.204, p<0.05). The more stable employment, the more unstable duty (r=-0.245, p<0.05), and the more unstable work, the higher the monthly income (r=-0.206, p<0.05) and the longer the career, the higher the monthly income (r=0.247, p<0.05). The more stable the employment, the more activities to improve physical function were found (r=0.341, p<0.05), and the more unstable the duty, the more activities to improve physical function were found (r=0.321, p<0.05), and the higher monthly income, the less physical function improvement activities (r=-0.196, p<0.05). Conclusions: It is necessary to provide regular services by a dedicated physical therapist for physical function improvement activities in order to improve the quality of life of the elderly in the future.