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당뇨병성 족부질환 여부에 따른 당뇨병 환자의 생활습관, 식습관, 자가관리 및 Diabetes fatalism (Lifestyle, Diet, Self-care, and Diabetes Fatalism of Diabetic Patients with and without Diabetic Foot)

  • 최정하;강주희;이홍미
    • 대한지역사회영양학회지
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    • 제19권3호
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    • pp.241-249
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    • 2014
  • 합병증으로 당뇨병성 족부질환을 가진 환자와 그렇지 않은 당뇨병 환자에서 DFS를 조사하고 이것이 생활습관, 식습관 및 당뇨병 자가 관리와 상관관계가 있는지 규명하고자 하였다. 1) 당뇨병성 족부질환군 69명(남/녀 48/21)과 일반당뇨군 59명(남/녀 33/26)으로 구성되었고, 당뇨병성 족부질환군이 일반당뇨군에 비해 당뇨병 유별기간이 유의적으로 길었으며(각각 $17.3{\pm}11.0$년, $11.3{\pm}9.46$년, p<0.01), 연령이 유의적으로 낮았고(각각 $51.2{\pm}11.6$세, $64.2{\pm}12.6$세, p<0.01), 기혼자의 비율이 유의적으로 낮았다 (p<0.05). 2) 당뇨병성 족부질환군은 일반당뇨군에 비해 부정적인 식사 특히, 패스트푸드, 배달음식, 인스턴트식품 및 편의점 음식의 섭취 빈도가 유의적으로 높은 반면(각각 $1.37{\pm}1.02$일/주와 $0.91{\pm}0.85$일/주, p<0.01), 긍정적인 식사 빈도와(각각 $2.74{\pm}1.76$일/주와 $3.61{\pm}2.05$일/주, p<0.01), 발 관리, 특히 발 씻기와 씻은 후 말리기의 빈도는 유의적으로 낮았다(각각 $4.61{\pm}1.97$일/주와 $5.53{\pm}2.22$ 일/주, p<0.05). 3) 12 항목으로 된 DFS의 Chronbach's ${\alpha}$는 당뇨병성 족부질환군에서 0.614로 매우 낮고, 자아효능감 관련 하부 영역의 세 항목은 제거되었을 때 내적일치도가 증가하였다. 따라서 당뇨병의 자가관리를 예측하는 인자로서 DFS의 유용성은 적어도 당뇨병성 족부질환 환자에서, 현재 12 항목의 DFS 도구로는 제한적임을 시사한다. 4) 당뇨병성 족부질환 합병증이 없는 일반당뇨군의 경우 12 항목 DFS는 Chronbach's ${\alpha}$가 0.869로 높고, 음주(r=0.247, p=0.059)와 부정적인 식사(r=0.241, p=0.066)와는 양의 상관관계가, 긍정적인 식사(r=-0.227, p=0.083)와는 음의 상관관계의 경향이 있었다. 자아효능감과 관련된 DFS와의 양의 상관관계는 음주(r=0.257, p<0.05), 흡연(r=0.350, p<0.01) 및 부정적 식습관(r=0.295, p<0.05)과 유의적이었고, 운동 (r=-0.224, p<0.088) 및 발 관리(r=-0.247, p<0.059)와는 경향이 있었다. 따라서 DFS는 적어도 당뇨병성 족부질환이 없는 환자의 경우에 특히 자아효능감 관련 항목에서 생활습관, 식습관 및 발 관리 충실도를 예측할 수 있는 도구로서의 잠재적 유용성을 있음을 제시한다. 본 연구에서는 당뇨병성 족부질환으로 족부 절단 위험에 처한 당뇨 환자가 그렇지 않은 당뇨 환자에 비해 식생활이 바람직하지 못할 뿐 아니라 발 관리가 잘 되고 있지 않음을 보여주어 비록 그 인과관계가 밝혀지지는 못했지만 당뇨병성 족부질환의 예방과 관리에서 당뇨 환자를 위한 식생활과 발관리 교육의 중요성이 확인되었다. 또한 이 연구는 우리나라에서 당뇨환자의 생활습관, 식습관 및 당뇨 자가관리를 예상할 수 있는 척도로서 미국에서 최근 개발된 DFS가 사용될 수 있는지 알아보는 첫 시도로 의미가 있는데 연구 결과는 종교, 당뇨병 형태, 심각한 합병증 유무에 따른 당뇨병 환자군별로 그 유용성을 규명할 필요성을 제시하였다.

The Phylotype of Thermus from the Rehai Geothermal Area, Tengchong, China

  • Guo, Chunlei;Wang, Tao;Zhu, Wei;Zhang, Donghua;Cui, Xiaolong;Xu, Lihua;Peng, Qian
    • Journal of Microbiology
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    • 제41권2호
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    • pp.152-156
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    • 2003
  • Through enrichment on two nutrient agars, 57 Thermus isolates were recovered from 15 hot spring samples taken from the Rehai geothermal area, Tengchong, China. Unique growth characteristics were observed when the strains were transferred from YIM14 medium to Thermus medium. Phylogenetic analysis showed that the 16S rDNA sequences of the isolates and clones from the Rehai geothermal area farmed a monophyletic group on the phylogenetic tree. A secondary structure comparison showed that their 16S rRNAs have unique secondary structure characteristics.

노화촉진 생쥐에서 노화에 따른 활성산소 생성 및 항산화능의 변화 (Age-associated Alteration in the Hapatic Superoxide Generation and Antioxidant Activities in the Senescence-accelerated Mice)

  • 정해영;김윤경
    • 약학회지
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    • 제36권5호
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    • pp.460-468
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    • 1992
  • Several bichemical parameters related to free radicals were estimated in senile-prone (P) and resistant(R) strains of male senescence-accelerated mice(SAM) at 2, 5 and 11 months of age. The superoxide generation was increased with age in SAM-R/1 and SAM-P/2. Compared to SAM-R/1, more generation of superoxide was significantly noted in the SAM-P/2 liver. The activities of Cu/Zn-superoxide dismutase and catalase were decreased during aging and these activities in SAM-P/2 were significantly lower than in SAM-R/l liver. The activities of glutathione S-transferase were varied with aging, whereas SAM-P/2 showed lower levels compared to SAM-R/l. The gradual decreases of glutathione, protein bound-SH and nonprotein bound-SH contents were noted with increasing age. SAM-P/2 liver contained lesser amounts of glutathione and nonprotein bound-SH compared to SAM-R. In conclusion, superoxide generation was increased whereas the antioxidant enzyme activities were decreased during aging in SAM-R/1. In addition, SAM-P/2 strain showed more superoxide generation and less antioxidant enzyme activities than SAM-R/1 in the liver, thus we assume that these factors might accelerate the senescence of SAM-P/2 strain.

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Limit of the Ratio of Incomplete Beta Functions

  • Hong, Yeon-Woong
    • Journal of the Korean Data and Information Science Society
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    • 제7권2호
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    • pp.289-294
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    • 1996
  • This paper considers the limit of the ratio of two incomplete beta functions $I_{x}(p+s,q+r)\;to\;I_{x}(p,q)\;as\;p+q{\rightarrow}{\infty}$. The results show that the limits depend on r,s,x and the limit of p/(p+q).

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Species Identification of Five Penaeid Shrimps Using PCR-RFLP and SSCP Analyses of 16S Ribosomal DNA

  • Khamnamtong, Bavornlak;Klinbunga, Sirawut;Menasveta, Piamsak
    • BMB Reports
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    • 제38권4호
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    • pp.491-499
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    • 2005
  • DNA-based molecular markers for differentiation of five penaeid shrimps (Penaeus monodon, P. semisulcatus, Feneropenaeus merguiensis, Litopenaeus vannamei and Marsupenaeus japonicus) were developed based on polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and single-stranded conformation polymorphism (SSCP) of 16S ribosomal (r) DNA. Differentiation of P. monodon, P. semisulcatus and L. vannamei can be unambiguously carried out by PCR-RFLP of 16S $rDNA_{560}$ whereas P. semisulcatus and M. japonicus shared a BABB mitotype. These shrimps were successfully discriminated by SSCP analysis of 16S $rDNA_{560}$. Nevertheless, the amplification success for L. vannamei and F. merguiensis was not consistent when tested against larger sample sizes. As a result, 16S $rDNA_{560}$ of an individual representing the most common mitotype of each species was cloned and sequenced. The new primer pair was designed and tested against the large sample sizes (312 bp product, N = 185). The amplification success was consistent across all species. PCR-RFLP of 16S $rDNA_{312}$ was as effective as that of 16S $rDNA_{560}$. Differentiation of all shrimp species were successfully carried out by SSCP analysis.

Analysis of TP53 Polymorphisms in North Indian Sporadic Esophageal Cancer Patients

  • Kaur, Sukhpreet;Sambyal, Vasudha;Guleria, Kamlesh;Manjari, Mridu;Sudan, Meena;Uppal, Manjit Singh;Singh, Neeti Rajan;Singh, Gursimran;Singh, Harpreet
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권19호
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    • pp.8413-8422
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    • 2014
  • Background: To investigate the relationship of five TP53 polymorphisms (p.P47S, p.R72P, PIN3 ins16bp, p.R213R and r.13494g>a) with the esophageal cancer (EC) risk in North Indians. Materials and Methods: Genotyping of p.P47S, p.R72P, PIN3 ins16bp, p.R213R and r.13494g>a polymorphisms of TP53 in 136 sporadic EC patients and 136 controls using polymerase chain reaction and PCR-RFLP. Results: The frequencies of genotype RR, RP and PP of p.R72P polymorphism were 16.91 vs 26.47%, 58.82 vs 49.27% and 24.27 vs 24.27% among patients and controls respectively. We observed significantly increased frequency of RP genotype in cases as compared to controls (OR=1.87, 95% CI, 1.01-3.46, p=0.05). The frequencies of genotype A1A1, A1A2 and A2A2 of PIN3 ins16bp polymorphism were 69.12 vs 70.59%, 27.20 vs 25% and 3.68 vs 4.41% among patients and controls. There was no significant difference among genotype and allele distribution between patients and controls. The frequencies of genotype GG, GA and AA of r.13494g>a polymorphism were 62.50 vs 64.70%, 34.56 vs 30.15% and 2.94 vs 5.15% among patients and controls respectively. No significant difference between genotype and allele frequency was observed in the patients and controls. For p.P47S and p.R213R polymorphisms, all the cases and controls had homozygous wild type genotype. The RP-A1A1-GG genotype combination shows significant risk for EC (OR=2.01, 95%CI: 1.01-3.99, p=0.05). Conclusions: Among the five TP53 polymorphisms investigated, only p.R72P polymorphism may contributes to EC susceptibility.

Schiff Bases as Anticorrosive Additives for Mild Steel Corrosion in Acid Media

  • Abirami, M.;Sasikala, S.;Chitra, S.;Parameswari, K.;Selvaraj, A.
    • Corrosion Science and Technology
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    • 제8권1호
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    • pp.1-10
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    • 2009
  • The influence of Schiff bases on the corrosion inhibition of mild steel in 1 M $H_2SO_4$ have been investigated by weight loss, gasometry, impedance and polarization techniques. The results obtained reveal that these compounds act as good inhibitors. The inhibition efficiency of Schiff bases increased with concentration and synergistically increased on addition of chromate, sulphate and halide ions. Potentiodynamic polarization measurements clearly reveal that the investigated inhibitors are of mixed type but they are more cathodic in nature. The adsorption of these compounds on mild steel surface for both the acids were found to obey Langmuir adsorption isotherm. The surface morphology was studied by SEM and UV reflectance spectra.

임상간호사의 정서지능과 핵심자기평가가 경력몰입에 미치는 영향 (The Effects of Clinical Nurse's Emotional Intelligence and Core Self-evaluation on Career Commitment)

  • 조옥희;유양숙;황경혜
    • 디지털융복합연구
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    • 제16권9호
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    • pp.269-278
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    • 2018
  • 본 연구의 목적은 임상간호사의 정서지능과 핵심자기평가가 경력몰입에 미치는 영향을 파악하기 위함이다. 연구대상은 서울시 소재 2개 종합병원의 임상간호사 462명으로 2017년 5월부터 7월까지 구조화된 설문지를 이용하여 자료 수집하였다. 수집된 자료는 t-test, ANOVA, Pearson's correlation coefficients, 다중회귀분석을 통해 분석하였다. 연구결과, 정서지능 또는 핵심자기평가와 경력몰입 간에(r=.28, p<.001; r=.34, p<.001), 정서지능과 핵심자기평가 간에(r=.44, p<.001) 정 상관관계가 있었다. 임상간호사의 경력몰입에 영향을 미치는 요인으로 핵심자기평가, 배우자 유무, 정서지능, 직위, 주관적 건강상태, 근무부서가 확인되었다($R^2=.21$). 따라서 경력몰입을 높이기 위해서는 임상간호사의 주관적 건강상태에 따라 정서지능과 핵심자기평가 정도를 파악하고, 결혼, 직위, 근무부서를 고려한 경력개발 융합프로그램 개발이 필요하다.

옥수수의 색소 발현에 관련된 조직 특이성 조절유전자 R locus에 관하여 (Tissue Specific Gene Regulation of The Anthocyanin Synthesis Regulator Gene R in Maize)

  • 임용표
    • 한국식물학회:학술대회논문집
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    • 한국식물학회 1987년도 식물생명공학 심포지움 논문집 Proceedings of Symposia on Plant Biotechnology
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    • pp.323-347
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    • 1987
  • The R locus of maize in one of several genes that regulate the anthocyanin pigments throughout the body of the plant and seed. The R gene product may regulate pigment deposition by controlling the expression of the flavonoid biosynthetic gene pathway in a tissue-specific manner. To understand the basis for tissue specific regulation and allelic variation at R, the molecular study has been done by cloning a portion of the R complex by transposon tagging with Ac. R specific probe were cloned from the R-nj mutant induced by Ac insertion mutagenesis. From southern analysis of R-r complex using the R-nj probe, the structure of R-r was proposed that R-r containes the three elements, (P)(Q)(S). These elements may organize as the inversion triplication model which (S) sequence was inverted in relation to (P) and (Q). The R-sc derivated from R-mb or R-nj was cloned with R-nj probe, and molecular genetical data showed that R-sc containes tissue specific and tissue nonspecific area, and the sequencing of R-sc are progressed now.

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초고압 케이블용 반도전 재료에 미치는 가공 조제의 영향에 관한 연구 (Investigation on The Effects of Processing Aids in Semiconductive Compounds for Extra High Voltage Cables)

  • 이경원;이정희;이건주
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2002년도 추계학술대회 논문집 전기물성,응용부문
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    • pp.112-115
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    • 2002
  • The effects of processing aids(P.A.) in semicoductive compounds(S.C.) with highly loaded carbon black for extra high voltage cables were investigated. The processability of S.C. is improved as the contents of P.A. increased, however, the electrical, mechanical properties and smoothness of S.C. grew worse, especially for the S.C. which contains 5wt% of P.A., the volume resistivity after heat cycle which shows long term reliability increased about three times after 15cycles compared to the S.C. which contains no P.A. We inferred that it is caused by the action of P.A. as the insulating sites, thermal expansion of polymer matrix which leads the length between carbon blacks to shorten, and the decrease of degree of crosslinking. The change of ion contents which means cleanliness of S.C. is not occured regardless of the addition of P.A.

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